| Year |
Citation |
Score |
| 2022 |
Harrison JJEK, Passos DO, Bruhn JF, Bauman JD, Tuberty L, DeStefano JJ, Ruiz FX, Lyumkis D, Arnold E. Cryo-EM structure of the HIV-1 Pol polyprotein provides insights into virion maturation. Science Advances. 8: eabn9874. PMID 35857464 DOI: 10.1126/sciadv.abn9874 |
0.314 |
|
| 2022 |
DeStefano JJ, Iseni F, Tarbouriech N. Selection of Primer-Template Sequences That Bind with Enhanced Affinity to Vaccinia Virus E9 DNA Polymerase. Viruses. 14. PMID 35215961 DOI: 10.3390/v14020369 |
0.31 |
|
| 2021 |
Harrison JJEK, Tuske S, Das K, Ruiz FX, Bauman JD, Boyer PL, DeStefano JJ, Hughes SH, Arnold E. Crystal Structure of a Retroviral Polyprotein: Prototype Foamy Virus Protease-Reverse Transcriptase (PR-RT). Viruses. 13. PMID 34452360 DOI: 10.3390/v13081495 |
0.318 |
|
| 2020 |
Tuske S, Zheng J, Olson ED, Ruiz FX, Pascal BD, Hoang A, Bauman JD, Das K, DeStefano JJ, Musier-Forsyth K, Griffin PR, Arnold E. Integrative structural biology studies of HIV-1 reverse transcriptase binding to a high-affinity DNA aptamer. Current Research in Structural Biology. 2: 116-129. PMID 33870216 DOI: 10.1016/j.crstbi.2020.06.002 |
0.35 |
|
| 2019 |
Rose KM, Alves Ferreira-Bravo I, Li M, Craigie R, Ditzler MA, Holliger P, DeStefano JJ. Selection of 2'-Deoxy-2'-Fluoroarabino Nucleic Acid (FANA) Aptamers that Bind HIV-1 Integrase with Picomolar Affinity. Acs Chemical Biology. PMID 31560515 DOI: 10.1021/Acschembio.9B00237 |
0.517 |
|
| 2019 |
Das K, Martinez SE, DeStefano JJ, Arnold E. Structure of HIV-1 RT/dsRNA initiation complex prior to nucleotide incorporation. Proceedings of the National Academy of Sciences of the United States of America. PMID 30902895 DOI: 10.2210/Pdb6Hak/Pdb |
0.443 |
|
| 2018 |
DeStefano JJ, Alves Ferreira-Bravo I. A highly sensitive aptamer-based HIV reverse transcriptase detection assay. Journal of Virological Methods. 257: 22-28. PMID 29630943 DOI: 10.1016/J.Jviromet.2018.04.005 |
0.396 |
|
| 2018 |
Fenstermacher KJ, Achuthan V, Schneider TD, DeStefano JJ. An Evolutionary/Biochemical Connection Between Promoter- and Primer-Dependent Polymerases Revealed by Selective Evolution of Ligands by Exponential Enrichment (SELEX). Journal of Bacteriology. PMID 29339418 DOI: 10.1128/Jb.00579-17 |
0.476 |
|
| 2016 |
Achuthan V, Singh K, Sarafianos SG, DeStefano JJ. Physiological Mg2+ Conditions Significantly Alter the Inhibition of HIV-1 and HIV-2 Reverse Transcriptases by Nucleoside and Non-Nucleoside Inhibitors In Vitro. Biochemistry. PMID 27936595 DOI: 10.1021/Acs.Biochem.6B00943 |
0.353 |
|
| 2016 |
Das K, Balzarini J, Miller MT, Maguire AR, DeStefano JJ, Arnold E. Correction to Conformational States of HIV-1 Reverse Transcriptase for Nucleotide Incorporation vs Pyrophosphorolysis-Binding of Foscarnet. Acs Chemical Biology. PMID 27696816 DOI: 10.1021/Acschembio.6B00798 |
0.379 |
|
| 2016 |
Das K, Balzarini J, Miller MT, Maguire AR, DeStefano JJ, Arnold E. Conformational states of HIV-1 reverse transcriptase for nucleotide incorporation vs. pyrophosphorolysis - binding of foscarnet. Acs Chemical Biology. PMID 27192549 DOI: 10.1021/Acschembio.6B00187 |
0.462 |
|
| 2015 |
Achuthan V, DeStefano JJ. Primer Extension Reactions for the PCR- based α- complementation Assay. Bio-Protocol. 5. PMID 27500187 |
0.344 |
|
| 2015 |
Alves Ferreira-Bravo I, Cozens C, Holliger P, DeStefano JJ. Selection of 2'-deoxy-2'-fluoroarabinonucleotide (FANA) aptamers that bind HIV-1 reverse transcriptase with picomolar affinity. Nucleic Acids Research. 43: 9587-99. PMID 26476448 DOI: 10.1093/Nar/Gkv1057 |
0.487 |
|
| 2015 |
Chauhan J, Chen SE, Fenstermacher KJ, Naser-Tavakolian A, Reingewertz T, Salmo R, Lee C, Williams E, Raje M, Sundberg E, DeStefano JJ, Freire E, Fletcher S. Synthetic, structural mimetics of the β-hairpin flap of HIV-1 protease inhibit enzyme function. Bioorganic & Medicinal Chemistry. PMID 26474665 DOI: 10.1016/J.Bmc.2015.09.002 |
0.378 |
|
| 2015 |
Miller MT, Tuske S, Das K, DeStefano JJ, Arnold E. Structure of HIV-1 reverse transcriptase bound to a novel 38-mer hairpin template-primer DNA aptamer. Protein Science : a Publication of the Protein Society. PMID 26296781 DOI: 10.1002/Pro.2776 |
0.5 |
|
| 2015 |
Achuthan V, DeStefano JJ. Alternative divalent cations (Zn²⁺, Co²⁺, and Mn²⁺) are not mutagenic at conditions optimal for HIV-1 reverse transcriptase activity. Bmc Biochemistry. 16: 12. PMID 25934642 DOI: 10.1186/S12858-015-0041-X |
0.413 |
|
| 2014 |
Achuthan V, Keith BJ, Connolly BA, DeStefano JJ. Human immunodeficiency virus reverse transcriptase displays dramatically higher fidelity under physiological magnesium conditions in vitro. Journal of Virology. 88: 8514-27. PMID 24850729 DOI: 10.1128/Jvi.00752-14 |
0.39 |
|
| 2012 |
Nair GR, Dash C, Le Grice SF, DeStefano JJ. Viral reverse transcriptases show selective high affinity binding to DNA-DNA primer-templates that resemble the polypurine tract. Plos One. 7: e41712. PMID 22848574 DOI: 10.1371/Journal.Pone.0041712 |
0.514 |
|
| 2012 |
Lai YT, DeStefano JJ. DNA aptamers to human immunodeficiency virus reverse transcriptase selected by a primer-free SELEX method: characterization and comparison with other aptamers. Nucleic Acid Therapeutics. 22: 162-76. PMID 22554064 DOI: 10.1089/Nat.2011.0327 |
0.695 |
|
| 2011 |
Fenstermacher KJ, DeStefano JJ. Mechanism of HIV reverse transcriptase inhibition by zinc: formation of a highly stable enzyme-(primer-template) complex with profoundly diminished catalytic activity. The Journal of Biological Chemistry. 286: 40433-42. PMID 21953456 DOI: 10.1074/Jbc.M111.289850 |
0.332 |
|
| 2011 |
Lai YT, DeStefano JJ. A primer-free method that selects high-affinity single-stranded DNA aptamers using thermostable RNA ligase. Analytical Biochemistry. 414: 246-53. PMID 21420926 DOI: 10.1016/J.Ab.2011.03.018 |
0.675 |
|
| 2010 |
Gangaramani DR, Eden EL, Shah M, Destefano JJ. The twenty-nine amino acid C-terminal cytoplasmic domain of poliovirus 3AB is critical for nucleic acid chaperone activity. Rna Biology. 7: 820-9. PMID 21045553 DOI: 10.4161/Rna.7.6.13781 |
0.671 |
|
| 2010 |
Olimpo JT, DeStefano JJ. Duplex structural differences and not 2'-hydroxyls explain the more stable binding of HIV-reverse transcriptase to RNA-DNA versus DNA-DNA. Nucleic Acids Research. 38: 4426-35. PMID 20338878 DOI: 10.1093/Nar/Gkq169 |
0.521 |
|
| 2010 |
DeStefano JJ. Effect of reaction conditions and 3AB on the mutation rate of poliovirus RNA-dependent RNA polymerase in a alpha-complementation assay. Virus Research. 147: 53-9. PMID 19850090 DOI: 10.1016/J.Virusres.2009.10.006 |
0.452 |
|
| 2008 |
DeStefano JJ, Nair GR. Novel aptamer inhibitors of human immunodeficiency virus reverse transcriptase. Oligonucleotides. 18: 133-44. PMID 18637731 DOI: 10.1089/Oli.2008.0103 |
0.477 |
|
| 2008 |
Jacob DT, DeStefano JJ. A new role for HIV nucleocapsid protein in modulating the specificity of plus strand priming. Virology. 378: 385-96. PMID 18632127 DOI: 10.1016/J.Virol.2008.06.002 |
0.516 |
|
| 2007 |
Anthony RM, Destefano JJ. In vitro synthesis of long DNA products in reactions with HIV-RT and nucleocapsid protein. Journal of Molecular Biology. 365: 310-24. PMID 17070544 DOI: 10.1016/J.Jmb.2006.10.007 |
0.488 |
|
| 2006 |
Baird HA, Gao Y, Galetto R, Lalonde M, Anthony RM, Giacomoni V, Abreha M, Destefano JJ, Negroni M, Arts EJ. Influence of sequence identity and unique breakpoints on the frequency of intersubtype HIV-1 recombination. Retrovirology. 3: 91. PMID 17164002 DOI: 10.1186/1742-4690-3-91 |
0.392 |
|
| 2006 |
Narayanan N, Gorelick RJ, DeStefano JJ. Structure/function mapping of amino acids in the N-terminal zinc finger of the human immunodeficiency virus type 1 nucleocapsid protein: residues responsible for nucleic acid helix destabilizing activity. Biochemistry. 45: 12617-28. PMID 17029416 DOI: 10.1021/Bi060925C |
0.72 |
|
| 2006 |
Bohlayer WP, DeStefano JJ. Tighter binding of HIV reverse transcriptase to RNA-DNA versus DNA-DNA results mostly from interactions in the polymerase domain and requires just a small stretch of RNA-DNA. Biochemistry. 45: 7628-38. PMID 16768458 DOI: 10.1021/Bi051770W |
0.506 |
|
| 2006 |
DeStefano JJ, Titilope O. Poliovirus protein 3AB displays nucleic acid chaperone and helix-destabilizing activities. Journal of Virology. 80: 1662-71. PMID 16439523 DOI: 10.1128/Jvi.80.4.1662-1671.2006 |
0.536 |
|
| 2006 |
DeStefano JJ, Cristofaro JV. Selection of primer-template sequences that bind human immunodeficiency virus reverse transcriptase with high affinity. Nucleic Acids Research. 34: 130-9. PMID 16397296 DOI: 10.1093/Nar/Gkj426 |
0.782 |
|
| 2005 |
Heath MJ, Destefano JJ. A complementary single-stranded docking site is required for enhancement of strand exchange by human immunodeficiency virus nucleocapsid protein on substrates that model viral recombination. Biochemistry. 44: 3915-25. PMID 15751967 DOI: 10.1021/Bi0477945 |
0.762 |
|
| 2004 |
Derebail SS, DeStefano JJ. Mechanistic analysis of pause site-dependent and -independent recombinogenic strand transfer from structurally diverse regions of the HIV genome. The Journal of Biological Chemistry. 279: 47446-54. PMID 15342633 DOI: 10.1074/Jbc.M408927200 |
0.797 |
|
| 2003 |
Heath MJ, Derebail SS, Gorelick RJ, DeStefano JJ. Differing roles of the N- and C-terminal zinc fingers in human immunodeficiency virus nucleocapsid protein-enhanced nucleic acid annealing. The Journal of Biological Chemistry. 278: 30755-63. PMID 12783894 DOI: 10.1074/Jbc.M303819200 |
0.771 |
|
| 2003 |
Liesch GR, DeStefano JJ. Analysis of mutations made during active synthesis or extension of mismatched substrates further define the mechanism of HIV-RT mutagenesis. Biochemistry. 42: 5925-36. PMID 12741851 DOI: 10.1021/Bi026998N |
0.402 |
|
| 2003 |
Derebail SS, Heath MJ, DeStefano JJ. Evidence for the differential effects of nucleocapsid protein on strand transfer in various regions of the HIV genome. The Journal of Biological Chemistry. 278: 15702-12. PMID 12595541 DOI: 10.1074/Jbc.M211701200 |
0.793 |
|
| 2003 |
Raja A, DeStefano JJ. Interaction of HIV reverse transcriptase with structures mimicking recombination intermediates. The Journal of Biological Chemistry. 278: 10102-11. PMID 12533519 DOI: 10.1074/Jbc.M210201200 |
0.734 |
|
| 2002 |
Cristofaro JV, Rausch JW, Le Grice SF, DeStefano JJ. Mutations in the ribonuclease H active site of HIV-RT reveal a role for this site in stabilizing enzyme-primer-template binding. Biochemistry. 41: 10968-75. PMID 12206668 DOI: 10.1021/Bi025871V |
0.784 |
|
| 2001 |
DeStefano JJ, Cristofaro JV, Derebail S, Bohlayer WP, Fitzgerald-Heath MJ. Physical mapping of HIV reverse transcriptase to the 5' end of RNA primers. The Journal of Biological Chemistry. 276: 32515-21. PMID 11441011 DOI: 10.1074/Jbc.M103958200 |
0.753 |
|
| 2001 |
Rodriguez-Wells V, Plotch SJ, DeStefano JJ. Primer-dependent synthesis by poliovirus RNA-dependent RNA polymerase (3Dpol) Nucleic Acids Research. 29: 2715-2724. PMID 11433016 DOI: 10.1093/Nar/29.13.2715 |
0.441 |
|
| 2001 |
Wells VR, Plotch SJ, DeStefano JJ. Determination of the mutation rate of poliovirus RNA-dependent RNA polymerase Virus Research. 74: 119-132. PMID 11226580 DOI: 10.1016/S0168-1702(00)00256-2 |
0.43 |
|
| 2000 |
DeStefano JJ, Raja A, Cristofaro JV. In vitro strand transfer from broken RNAs results in mismatch but not frameshift mutations. Virology. 276: 7-15. PMID 11021989 DOI: 10.1006/Viro.2000.0533 |
0.791 |
|
| 2000 |
Diaz L, Cristofaro JV, DeStefano JJ. Human immunodeficiency virus reverse transcriptase base misincorporations can promote strand transfer. Archives of Virology. 145: 1117-31. PMID 10948986 DOI: 10.1007/S007050070113 |
0.803 |
|
| 1999 |
Raja A, DeStefano JJ. Kinetic analysis of the effect of HIV nucleocapsid protein (NCp) on internal strand transfer reactions. Biochemistry. 38: 5178-84. PMID 10213624 DOI: 10.1021/Bi9828019 |
0.739 |
|
| 1998 |
DeStefano J, Ghosh J, Prasad B, Raja A. High fidelity of internal strand transfer catalyzed by human immunodeficiency virus reverse transcriptase Journal of Biological Chemistry. 273: 1483-1489. PMID 9430686 DOI: 10.1074/Jbc.273.3.1483 |
0.698 |
|
| 1997 |
DeStefano JJ, Roberts B, Shriner D. The mechanism of retroviral recombination: The role of sequences proximal to the point of strand transfer Archives of Virology. 142: 1797-1812. PMID 9672638 DOI: 10.1007/S007050050198 |
0.519 |
|
| 1996 |
Diaz L, DeStefano JJ. Strand transfer is enhanced by mismatched nucleotides at the 3' primer terminus: A possible link between HIV reverse transcriptase fidelity and recombination Nucleic Acids Research. 24: 3086-3092. PMID 8760898 DOI: 10.1093/Nar/24.15.3086 |
0.551 |
|
| 1996 |
DeStefano JJ. Interaction of human immunodeficiency virus nucleocapsid protein with a structure mimicking a replication intermediate: Effects on stability, reverse transcriptase binding, and strand transfer Journal of Biological Chemistry. 271: 16350-16356. PMID 8663119 DOI: 10.1074/Jbc.271.27.16350 |
0.57 |
|
| 1995 |
DeStefano JJ. Human immunodeficiency virus nucleocapsid protein stimulates strand transfer from internal regions of heteropolymeric RNA templates Archives of Virology. 140: 1775-1789. PMID 7503678 DOI: 10.1007/Bf01384341 |
0.553 |
|
| 1995 |
Destefano JJ. The orientation of binding of human immunodeficiency virus reverse transcriptase on nucleic acid hybrids Nucleic Acids Research. 23: 3901-3908. PMID 7479034 DOI: 10.1093/Nar/23.19.3901 |
0.549 |
|
| 1994 |
DeStefano JJ. Kinetic analysiss of the catalysis of strand transfer from internal regions of heteropolymeric RNA templates by human immunodeficiency virus reverse transcriptase Journal of Molecular Biology. 243: 558-567. PMID 7525968 DOI: 10.1016/0022-2836(94)90030-2 |
0.543 |
|
| 1994 |
Destefano JJ, Mallaber LM, Fay PJ, Bambara RA. Quantitative analysis of RNA cleavage during rnadirected DNA synthesis by human immunodeficiency and avian myeloblastosis virus reverse transcriptases Nucleic Acids Research. 22: 3793-3800. PMID 7524028 DOI: 10.1093/Nar/22.18.3793 |
0.529 |
|
| 1994 |
DeStefano JJ, Wu W, Seehra J, McCoy J, Laston D, Albone E, Fay PJ, Bambara RA. Characterization of an RNase H deficient mutant of human immunodeficiency virus-1 reverse transcriptase having an aspartate to asparagine change at position 498 Bba - Gene Structure and Expression. 1219: 380-388. PMID 7522572 DOI: 10.1016/0167-4781(94)90062-0 |
0.396 |
|
| 1994 |
DeStefano JJ, Bambara RA, Fay PJ. The mechanism of human immunodeficiency virus reverse transcriptase-catalyzed strand transfer from internal regions of heteropolymeric RNA templates Journal of Biological Chemistry. 269: 161-168. PMID 7506252 |
0.467 |
|
| 1993 |
Destefano JJ, Mallaber LM, Fay PJ, Bambara RA. Determinants of the RNAse H cleavage specificity of human immunodeficiency virus reverse transcriptase Nucleic Acids Research. 21: 4330-4338. PMID 7692401 DOI: 10.1093/Nar/21.18.4330 |
0.526 |
|
| 1993 |
DeStefano JJ, Bambara RA, Fay PJ. Parameters that influence the binding of human immunodeficiency virus reverse transcriptase to nucleic acid structures Biochemistry. 32: 6908-6915. PMID 7687463 DOI: 10.1021/Bi00078A014 |
0.503 |
|
| 1992 |
Destefano JJ, Mallaber LM, Rodriguez-Rodriguez L, Fay PJ, Bambara RA. Requirements for strand transfer between internal regions of heteropolymer templates by human immunodeficiency virus reverse transcriptase Journal of Virology. 66: 6370-6378. PMID 1383563 DOI: 10.1128/Jvi.66.11.6370-6378.1992 |
0.562 |
|
| 1992 |
DeStefano JJ, Buiser RG, Mallaber LM, Fay PJ, Bambara RA. Parameters that influence processive synthesis and site-specific termination by human immunodeficiency virus reverse transcriptase on RNA and DNA templates Bba - Gene Structure and Expression. 1131: 270-280. PMID 1378301 DOI: 10.1016/0167-4781(92)90025-U |
0.537 |
|
| 1991 |
DeStefano JJ, Buiser RG, Mallaber LM, Bambara RA, Fay PJ. Human immunodeficiency virus reverse transcriptase displays a partially processive 3′ to 5′ endonuclease activity Journal of Biological Chemistry. 266: 24295-24301. PMID 1722202 |
0.356 |
|
| 1991 |
Buiser RG, Destefano JJ, Mallaber LM, Fay PJ, Bambara RA. Requirements for the catalysis of strand transfer synthesis by retroviral DNA polymerases Journal of Biological Chemistry. 266: 13103-13109. PMID 1712774 |
0.42 |
|
| 1991 |
DeStefano JJ, Buiser RG, Mallaber LM, Myers TW, Bambara RA, Fay PJ. Polymerization and RNase H activities of the reverse transcriptases from avian myeloblastosis, human immunodeficiency, and moloney murine leukemia viruses are functionally uncoupled Journal of Biological Chemistry. 266: 7423-7431. PMID 1708386 |
0.4 |
|
| 1990 |
Destefano J, Olmsted E, Panniers R, Lucas-Lenard J. The α Subunit of Eucaryotic Initiation Factor 2 Is Phosphorylated in Mengovirus-Infected Mouse L Cells Journal of Virology. 64: 4445-4453. PMID 2166823 DOI: 10.1128/Jvi.64.9.4445-4453.1990 |
0.316 |
|
| Show low-probability matches. |