Robert W. Schnepp, Ph.D. - Publications

Affiliations: 
2006 University of Pennsylvania, Philadelphia, PA, United States 
Area:
Molecular Biology, Cell Biology

27 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Shahab SW, Roggeveen CM, Sun J, Kunhiraman H, McSwain LF, Juraschka K, Kumar SA, Saulnier O, Taylor MD, Schniederjan M, Schnepp RW, MacDonald TJ, Kenney AM. The LIN28B-let-7-PBK pathway is essential for group 3 medulloblastoma tumor growth and survival. Molecular Oncology. PMID 37341142 DOI: 10.1002/1878-0261.13477  0.317
2021 Shields CE, Potlapalli S, Cuya-Smith SM, Chappell SK, Chen D, Martinez D, Pogoriler J, Rathi KS, Patel SA, Oristian KM, Linardic CM, Maris JM, Haynes KA, Schnepp RW. Epigenetic regulator BMI1 promotes alveolar rhabdomyosarcoma proliferation and constitutes a novel therapeutic target. Molecular Oncology. PMID 33523558 DOI: 10.1002/1878-0261.12914  0.344
2020 Shim J, Lee JY, Jonus HC, Arnold A, Schnepp RW, Janssen KM, Maximov V, Goldsmith KC. YAP-mediated repression of HRK regulates tumor growth, therapy response, and survival under tumor environmental stress in neuroblastoma. Cancer Research. PMID 32900773 DOI: 10.1158/0008-5472.CAN-20-0025  0.36
2015 Schnepp RW, Khurana P, Attiyeh EF, Raman P, Chodosh SE, Oldridge DA, Gagliardi ME, Conkrite KL, Asgharzadeh S, Seeger RC, Madison BB, Rustgi AK, Maris JM, Diskin SJ. A LIN28B-RAN-AURKA Signaling Network Promotes Neuroblastoma Tumorigenesis. Cancer Cell. 28: 599-609. PMID 26481147 DOI: 10.1016/J.Ccell.2015.09.012  0.382
2015 Healy JR, Schnepp RW, Hart LS, Raman P, Danielson L, Russell M, Khurana P, Gagliardi M, Kinsey RM, Wyce A, Barbash O, Tummino PJ, Chesler L, Maris JM. Abstract B34: Antitumor activity and sensitivity evaluation of novel BET inhibitors in neuroblastoma Molecular Cancer Research. 13. DOI: 10.1158/1557-3125.Myc15-B34  0.448
2015 Schnepp RW, Khurana P, Attiyeh EF, Chodosh S, Raman P, Oldridge DA, Gagliardi ME, Conkrite K, Asgharzadeh S, Seeger RC, Madison B, Rustgi A, Maris JM, Diskin SJ. Abstract 4734: A LIN28B/RAN/AURKA signaling network promotes neuroblastoma tumorigenesis Cancer Research. 75: 4734-4734. DOI: 10.1158/1538-7445.Am2015-4734  0.46
2014 Schnepp R, Hart L, Raman P, Danielson L, Gagliardi M, Kinsey R, Wyce A, Barbash O, Tummino P, Chesler L, Maris J. Abstract B75: Defining the antitumor activity and sensitivity profiles of BET inhibitors in neuroblastoma Cancer Research. 74. DOI: 10.1158/1538-7445.Pedcan-B75  0.435
2013 Rader J, Russell MR, Hart LS, Nakazawa MS, Belcastro LT, Martinez D, Li Y, Carpenter EL, Attiyeh EF, Diskin SJ, Kim S, Parasuraman S, Caponigro G, Schnepp RW, Wood AC, et al. Dual CDK4/CDK6 inhibition induces cell-cycle arrest and senescence in neuroblastoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 6173-82. PMID 24045179 DOI: 10.1158/1078-0432.Ccr-13-1675  0.362
2013 Schnepp RW, Maris JM. Targeting MYCN: a good BET for improving neuroblastoma therapy? Cancer Discovery. 3: 255-7. PMID 23475876 DOI: 10.1158/2159-8290.Cd-13-0018  0.315
2013 Schnepp RW, Attiyeh EF, Gagliardi ME, Chodosh S, Maris JM, Diskin SJ. Abstract 3809: The role ofLIN28BandRANin promoting neuroblastoma tumorigenesis. Cancer Research. 73: 3809-3809. DOI: 10.1158/1538-7445.Am2013-3809  0.327
2013 Rader J, Hart L, Russell M, Nakazawa M, Belcastro L, Martinez D, Carpenter E, Kim S, Parasuraman S, Caponigro G, Schnepp R, Wood A, Pawel B, Watson D, Warren P, et al. Abstract 2744: CDK4/CDK6 inhibition is potently active in a definable subset of human neuroblastomas. Cancer Research. 73: 2744-2744. DOI: 10.1158/1538-7445.Am2013-2744  0.421
2012 Diskin SJ, Capasso M, Schnepp RW, Cole KA, Attiyeh EF, Hou C, Diamond M, Carpenter EL, Winter C, Lee H, Jagannathan J, Latorre V, Iolascon A, Hakonarson H, Devoto M, et al. Common variation at 6q16 within HACE1 and LIN28B influences susceptibility to neuroblastoma. Nature Genetics. 44: 1126-30. PMID 22941191 DOI: 10.1038/Ng.2387  0.312
2012 Bosse KR, Diskin SJ, Cole KA, Wood AC, Schnepp RW, Norris G, Nguyen le B, Jagannathan J, Laquaglia M, Winter C, Diamond M, Hou C, Attiyeh EF, Mosse YP, Pineros V, et al. Common variation at BARD1 results in the expression of an oncogenic isoform that influences neuroblastoma susceptibility and oncogenicity. Cancer Research. 72: 2068-78. PMID 22350409 DOI: 10.1158/0008-5472.Can-11-3703  0.395
2012 Diskin SJ, Capasso M, Latorre V, Schnepp R, Attiyeh EF, Diamond M, Hou C, Carpenter EL, Lee H, Cole KA, Asgharzadeh S, Hakonarson H, Devoto M, Maris JM. Abstract 4871: New neuroblastoma susceptibility loci at 6q21 withinHACE1andLIN28B Cancer Research. 72: 4871-4871. DOI: 10.1158/1538-7445.Am2012-4871  0.404
2011 Wang K, Diskin SJ, Zhang H, Attiyeh EF, Winter C, Hou C, Schnepp RW, Diamond M, Bosse K, Mayes PA, Glessner J, Kim C, Frackelton E, Garris M, Wang Q, et al. Integrative genomics identifies LMO1 as a neuroblastoma oncogene. Nature. 469: 216-20. PMID 21124317 DOI: 10.1038/Nature09609  0.377
2007 La P, Yang Y, Karnik SK, Silva AC, Schnepp RW, Kim SK, Hua X. Menin-mediated caspase 8 expression in suppressing multiple endocrine neoplasia type 1. The Journal of Biological Chemistry. 282: 31332-40. PMID 17766243 DOI: 10.1074/Jbc.M609555200  0.598
2006 Schnepp RW, Chen YX, Wang H, Cash T, Silva A, Diehl JA, Brown E, Hua X. Mutation of tumor suppressor gene Men1 acutely enhances proliferation of pancreatic islet cells. Cancer Research. 66: 5707-15. PMID 16740708 DOI: 10.1158/0008-5472.Can-05-4518  0.601
2006 La P, Desmond A, Hou Z, Silva AC, Schnepp RW, Hua X. Tumor suppressor menin: the essential role of nuclear localization signal domains in coordinating gene expression. Oncogene. 25: 3537-46. PMID 16449969 DOI: 10.1038/Sj.Onc.1209400  0.635
2005 Milne TA, Hughes CM, Lloyd R, Yang Z, Rozenblatt-Rosen O, Dou Y, Schnepp RW, Krankel C, Livolsi VA, Gibbs D, Hua X, Roeder RG, Meyerson M, Hess JL. Menin and MLL cooperatively regulate expression of cyclin-dependent kinase inhibitors. Proceedings of the National Academy of Sciences of the United States of America. 102: 749-54. PMID 15640349 DOI: 10.1073/Pnas.0408836102  0.633
2004 Schnepp RW, Hou Z, Wang H, Petersen C, Silva A, Masai H, Hua X. Functional interaction between tumor suppressor menin and activator of S-phase kinase. Cancer Research. 64: 6791-6. PMID 15374998 DOI: 10.1158/0008-5472.Can-04-0724  0.617
2004 La P, Silva AC, Hou Z, Wang H, Schnepp RW, Yan N, Shi Y, Hua X. Direct binding of DNA by tumor suppressor menin. The Journal of Biological Chemistry. 279: 49045-54. PMID 15331604 DOI: 10.1074/Jbc.M409358200  0.565
2004 La P, Schnepp RW, D Petersen C, C Silva A, Hua X. Tumor suppressor menin regulates expression of insulin-like growth factor binding protein 2. Endocrinology. 145: 3443-50. PMID 15044367 DOI: 10.1210/En.2004-0124  0.65
2004 Schnepp RW, Mao H, Sykes SM, Zong WX, Silva A, La P, Hua X. Menin induces apoptosis in murine embryonic fibroblasts. The Journal of Biological Chemistry. 279: 10685-91. PMID 14688275 DOI: 10.1074/Jbc.M308073200  0.598
2003 Jin S, Mao H, Schnepp RW, Sykes SM, Silva AC, D'Andrea AD, Hua X. Menin associates with FANCD2, a protein involved in repair of DNA damage. Cancer Research. 63: 4204-10. PMID 12874027  0.544
2003 Schnepp R, Hua X. A tumor-suppressing duo: TGFbeta and activin modulate a similar transcriptome. Cancer Biology & Therapy. 2: 171-2. PMID 12750557 DOI: 10.4161/Cbt.2.2.334  0.547
2003 La P, Morgan TA, Sykes SM, Mao H, Schnepp RW, Petersen CD, Hua X. Fusion proteins of retinoid receptors antagonize TGF-beta-induced growth inhibition of lung epithelial cells. Oncogene. 22: 198-210. PMID 12527889 DOI: 10.1038/Sj.Onc.1206100  0.528
2002 Chen F, Kook H, Milewski R, Gitler AD, Lu MM, Li J, Nazarian R, Schnepp R, Jen K, Biben C, Runke G, Mackay JP, Novotny J, Schwartz RJ, Harvey RP, et al. Hop is an unusual homeobox gene that modulates cardiac development. Cell. 110: 713-23. PMID 12297045 DOI: 10.1016/S0092-8674(02)00932-7  0.358
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