Year |
Citation |
Score |
2023 |
Sulaiman MI, Alabsi W, Szabo L, Hay M, Polt R, Largent-Milnes TM, Vanderah TW. PNA6, a Lactosyl Analogue of Angiotensin-(1-7), Reverses Pain Induced in Murine Models of Inflammation, Chemotherapy-Induced Peripheral Neuropathy, and Metastatic Bone Disease. International Journal of Molecular Sciences. 24. PMID 37834455 DOI: 10.3390/ijms241915007 |
0.789 |
|
2023 |
Thompson AL, Grenald SA, Ciccone HA, Mohty D, Smith AF, Coleman DL, Bahramnejad E, De Leon E, Kasper-Conella L, Uhrlab JL, Margolis DS, Salvemini D, Largent-Milnes TM, Vanderah TW. Morphine-induced osteolysis and hypersensitivity is mediated through toll-like receptor-4 in a murine model of metastatic breast cancer. Pain. PMID 37326644 DOI: 10.1097/j.pain.0000000000002953 |
0.792 |
|
2023 |
Liktor-Busa E, Levine AA, Palomino SM, Singh S, Wahl J, Vanderah TW, Stella N, Largent-Milnes TM. ABHD6 and MAGL control 2-AG levels in the PAG and allodynia in a CSD-induced periorbital model of headache. Frontiers in Pain Research (Lausanne, Switzerland). 4: 1171188. PMID 37287623 DOI: 10.3389/fpain.2023.1171188 |
0.743 |
|
2023 |
Wiese BM, Alvarez Reyes A, Vanderah TW, Largent-Milnes TM. The endocannabinoid system and breathing. Frontiers in Neuroscience. 17: 1126004. PMID 37144090 DOI: 10.3389/fnins.2023.1126004 |
0.735 |
|
2022 |
Vizcarra VS, Barber KR, Franca-Solomon G, Majuta L, Smith A, Langlais PR, Largent-Milnes TM, Vanderah TW, Riegel AC. Targeting 5-HT receptors and Kv7 channels in PFC to attenuate chronic neuropathic pain in rats using a spared nerve injury model. Neuroscience Letters. 789: 136864. PMID 36063980 DOI: 10.1016/j.neulet.2022.136864 |
0.766 |
|
2022 |
Bruhns RP, Sulaiman MI, Gaub M, Bae EH, Davidson Knapp RB, Larson AR, Smith A, Coleman DL, Staatz WD, Sandweiss AJ, Joseph B, Hay M, Largent-Milnes TM, Vanderah TW. Angiotensin-(1-7) improves cognitive function and reduces inflammation in mice following mild traumatic brain injury. Frontiers in Behavioral Neuroscience. 16: 903980. PMID 35990729 DOI: 10.3389/fnbeh.2022.903980 |
0.776 |
|
2022 |
Wahl JR, Vivek A, Palomino SM, Almuslim M, Cottier KE, Langlais PR, Streicher JM, Vanderah TW, Liktor-Busa E, Largent-Milnes TM. Extracellular Alterations in pH and K+ Modify the Murine Brain Endothelial Cell Total and Phospho-Proteome. Pharmaceutics. 14. PMID 35890365 DOI: 10.3390/pharmaceutics14071469 |
0.774 |
|
2022 |
Kwak EA, Pan CC, Ramonett A, Kumar S, Cruz-Flores P, Ahmed T, Ortiz HR, Lochhead JJ, Ellis NA, Mouneimne G, Georgieva TG, Lee YS, Vanderah TW, Largent-Milnes T, Mohler PJ, et al. β-spectrin as a stalk cell-intrinsic regulator of VEGF signaling. Nature Communications. 13: 1326. PMID 35288568 DOI: 10.1038/s41467-022-28933-1 |
0.766 |
|
2021 |
Wiese BM, Liktor-Busa E, Couture SA, Nikas SP, Ji L, Liu Y, Makriyannis A, Spigelman I, Vanderah TW, Largent-Milnes TM. Brain Penetrant, but not Peripherally Restricted, Synthetic Cannabinoid 1 Receptor Agonists Promote Morphine-Mediated Respiratory Depression. Cannabis and Cannabinoid Research. PMID 34935460 DOI: 10.1089/can.2021.0090 |
0.759 |
|
2021 |
Levine A, Liktor-Busa E, Lipinski AA, Couture S, Balasubramanian S, Aicher SA, Langlais PR, Vanderah TW, Largent-Milnes TM. Sex differences in the expression of the endocannabinoid system within V1M cortex and PAG of Sprague Dawley rats. Biology of Sex Differences. 12: 60. PMID 34749819 DOI: 10.1186/s13293-021-00402-2 |
0.809 |
|
2021 |
Ramonett A, Kwak EA, Ahmed T, Flores PC, Ortiz HR, Lee YS, Vanderah TW, Largent-Milnes T, Kashatus DF, Langlais PR, Mythreye K, Lee NY. Regulation of mitochondrial fission by GIPC-mediated Drp1 retrograde transport. Molecular Biology of the Cell. mbcE21060286. PMID 34705526 DOI: 10.1091/mbc.E21-06-0286 |
0.696 |
|
2021 |
Zhang H, Lipinski AA, Liktor-Busa E, Smith AF, Moutal A, Khanna R, Langlais PR, Largent-Milnes TM, Vanderah TW. The Effects of Repeated Morphine Treatment on the Endogenous Cannabinoid System in the Ventral Tegmental Area. Frontiers in Pharmacology. 12: 632757. PMID 33953672 DOI: 10.3389/fphar.2021.632757 |
0.78 |
|
2021 |
Blawn KT, Kellohen KL, Galloway EA, Wahl J, Vivek A, Verkhovsky VG, Barker NK, Cottier KE, Vallecillo TG, Langlais PR, Liktor-Busa E, Vanderah TW, Largent-Milnes TM. Sex hormones regulate NHE1 functional expression and brain endothelial proteome to control paracellular integrity of the blood endothelial barrier. Brain Research. 147448. PMID 33771519 DOI: 10.1016/j.brainres.2021.147448 |
0.758 |
|
2020 |
Wiese BM, Liktor-Busa E, Levine A, Couture SA, Nikas SP, Ji L, Liu Y, Mackie K, Makriyannis A, Largent-Milnes TM, Vanderah TW. Cannabinoid-2 Agonism with AM2301 Mitigates Morphine-Induced Respiratory Depression. Cannabis and Cannabinoid Research. PMID 33998869 DOI: 10.1089/can.2020.0076 |
0.768 |
|
2020 |
Levine A, Liktor-Busa E, Karlage KL, Giancotti L, Salvemini D, Vanderah TW, Largent-Milnes TM. DAGLα Inhibition as a Non-invasive and Translational Model of Episodic Headache. Frontiers in Pharmacology. 11: 615028. PMID 33584293 DOI: 10.3389/fphar.2020.615028 |
0.759 |
|
2020 |
Levine A, Vanderah TW, Largent-Milnes TM. An underrepresented majority: A systematic review utilizing allodynic criteria to examine the present scarcity of discrete animal models for episodic migraine. Cephalalgia : An International Journal of Headache. 333102420966984. PMID 33131303 DOI: 10.1177/0333102420966984 |
0.706 |
|
2020 |
Liktor-Busa E, Blawn KT, Kellohen KL, Wiese BM, Verkhovsky V, Wahl J, Vivek A, Palomino SM, Davis TP, Vanderah TW, Largent-Milnes TM. Functional NHE1 expression is critical to blood brain barrier integrity and sumatriptan blood to brain uptake. Plos One. 15: e0227463. PMID 32469979 DOI: 10.1371/Journal.Pone.0227463 |
0.755 |
|
2020 |
Doyle TM, Largent-Milnes TM, Chen Z, Staikopoulos V, Esposito E, Delgarno R, Fan C, Tosh DK, Cuzzocrea S, Jacobson KA, Trang T, Hutchinson MR, Bennett GJ, Vanderah TW, Salvemini D.
The Journal of Pharmacology and Experimental Therapeutics. PMID 32434943 DOI: 10.1124/Jpet.120.000004 |
0.809 |
|
2020 |
Lucarini E, Coppi E, Micheli L, Parisio C, Vona A, Cherchi F, Pugliese AM, Pedata F, Failli P, Palomino S, Wahl J, Largent-Milnes TM, Vanderah TW, Tosh DK, Jacobson KA, et al. Acute visceral pain relief mediated by A3AR agonists in rats: involvement of N-type voltage-gated calcium channels. Pain. PMID 32379223 DOI: 10.1097/J.Pain.0000000000001905 |
0.799 |
|
2020 |
Ellingson HM, Vanderah TW. Potential therapeutic treatments of cancer-induced bone pain. Current Opinion in Supportive and Palliative Care. 14: 107-111. PMID 32349095 DOI: 10.1097/SPC.0000000000000496 |
0.335 |
|
2020 |
Doyle TM, Janes K, Chen Z, Grace PM, Esposito E, Cuzzocrea S, Largent-Milnes TM, Neumann WL, Watkins LR, Spiegel S, Vanderah TW, Salvemini D. Activation of sphingosine-1-phosphate receptor subtype 1 in the central nervous system contributes to morphine-induced hyperalgesia and antinociceptive tolerance in rodents. Pain. PMID 32301840 DOI: 10.1097/J.Pain.0000000000001888 |
0.824 |
|
2020 |
Bartlett MJ, So LY, Szabò L, Skinner DP, Parent KL, Heien ML, Vanderah TW, Polt R, Sherman SJ, Falk T. Highly-selective µ-opioid receptor antagonism does not block L-DOPA-induced dyskinesia in a rodent model. Bmc Research Notes. 13: 149. PMID 32164786 DOI: 10.1186/S13104-020-04994-7 |
0.446 |
|
2020 |
Thompson AL, Grenald S, Ciccone H, BassiriRad N, Niphakis M, Cravatt B, Largent-Milnes TM, Vanderah TW. The Endocannabinoid System Alleviates Pain in a Murine Model of Cancer-Induced Bone Pain. The Journal of Pharmacology and Experimental Therapeutics. PMID 32054717 DOI: 10.1124/Jpet.119.262337 |
0.797 |
|
2020 |
Smith A, Flohrschutz A, Riegel A, Largent-Milnes T, Vanderah T. Functional Connectivity of Prelimic Prefrontal Cortex and Rostral Ventromedial Medulla for Descending Pain Modulation The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.03633 |
0.752 |
|
2019 |
Khanna R, Patwardhan A, Yang X, Li W, Cai S, Ji Y, Chew LA, Dorame A, Bellampalli SS, Schmoll RW, Gordon J, Moutal A, Vanderah TW, Porreca F, Ibrahim MM. Erratum to ‛Development and Characterization of An Injury-free Model of Functional Pain in Rats by Exposure to Red Light': The Journal of Pain 20 (2019) 1293-1306. The Journal of Pain : Official Journal of the American Pain Society. 20: 1509. PMID 31818395 DOI: 10.1016/J.Jpain.2019.11.012 |
0.55 |
|
2019 |
Zhang H, Largent-Milnes TM, Vanderah TW. Glial Neuroimmune Signaling in Opioid Reward. Brain Research Bulletin. PMID 31790721 DOI: 10.1016/J.Brainresbull.2019.11.012 |
0.788 |
|
2019 |
Moutal A, Luo S, Largent-Milnes TM, Vanderah TW, Khanna R. Cdk5-mediated CRMP2 phosphorylation is necessary and sufficient for peripheral neuropathic pain. Neurobiology of Pain (Cambridge, Mass.). 5. PMID 31080913 DOI: 10.1016/J.Ynpai.2018.07.003 |
0.783 |
|
2019 |
Chen Z, Doyle TM, Luongo L, Largent-Milnes TM, Giancotti LA, Kolar G, Squillace S, Boccella S, Walker JK, Pendleton A, Spiegel S, Neumann WL, Vanderah TW, Salvemini D. Sphingosine-1-phosphate receptor 1 activation in astrocytes contributes to neuropathic pain. Proceedings of the National Academy of Sciences of the United States of America. PMID 31068460 DOI: 10.1073/Pnas.1820466116 |
0.812 |
|
2019 |
Khanna R, Patwardhan A, Yang X, Li W, Cai S, Ji Y, Chew LA, Dorame A, Bellampalli SS, Schmoll RW, Gordon J, Moutal A, Vanderah TW, Porreca F, Ibrahim MM. Development and Characterization of An Injury-free Model of Functional Pain in Rats by Exposure to Red Light. The Journal of Pain : Official Journal of the American Pain Society. PMID 31054915 DOI: 10.1016/J.Jpain.2019.04.008 |
0.579 |
|
2019 |
Thompson AL, Largent-Milnes TM, Vanderah TW. Animal Models for the Study of Bone-Derived Pain. Methods in Molecular Biology (Clifton, N.J.). 1914: 391-407. PMID 30729479 DOI: 10.1007/978-1-4939-8997-3_23 |
0.776 |
|
2019 |
Moutal A, Dustrude ET, Largent-Milnes TM, Vanderah TW, Khanna M, Khanna R. Blocking CRMP2 SUMOylation reverses neuropathic pain. Molecular Psychiatry. 23: 2119-2121. PMID 28533518 DOI: 10.1038/Mp.2017.117 |
0.728 |
|
2018 |
Cottier KE, Galloway EA, Calabrese EC, Tome ME, Liktor-Busa E, Kim J, Davis TP, Vanderah TW, Largent-Milnes TM. Loss of Blood-Brain Barrier Integrity in a KCl-Induced Model of Episodic Headache Enhances CNS Drug Delivery. Eneuro. 5. PMID 30073201 DOI: 10.1523/ENEURO.0116-18.2018 |
0.782 |
|
2018 |
Zhang H, Lund DM, Ciccone HA, Staatz WD, Ibrahim MM, Largent-Milnes TM, Seltzman HH, Spigelman I, Vanderah TW. A peripherally restricted cannabinoid 1 receptor agonist as a novel analgesic in cancer-induced bone pain. Pain. PMID 29781960 DOI: 10.1097/J.Pain.0000000000001278 |
0.82 |
|
2018 |
Pandit V, Khan M, Zakaria ER, Largent-Milnes TM, Hamidi M, O'Keeffe T, Vanderah TW, Joseph B. Continuous Remote Ischemic Conditioning Attenuates Cognitive and Motor Deficits From Moderate Traumatic Brain Injury. The Journal of Trauma and Acute Care Surgery. PMID 29443855 DOI: 10.1097/Ta.0000000000001835 |
0.714 |
|
2018 |
Edwards KA, Havelin JJ, Mcintosh MI, Ciccone HA, Pangilinan K, Imbert I, Largent-Milnes TM, King T, Vanderah TW, Streicher JM. A Kappa Opioid Receptor Agonist Blocks Bone Cancer Pain Without Altering Bone Loss, Tumor Size, or Cancer Cell Proliferation in a Mouse Model of Cancer-Induced Bone Pain. The Journal of Pain : Official Journal of the American Pain Society. PMID 29371114 DOI: 10.1016/J.Jpain.2018.01.002 |
0.807 |
|
2018 |
Galloway EA, Cottier KE, Kim J, Vallecillo T, Davis TP, Vanderah TW, Largent-Milnes TM. Role of Sex Hormones in Regulation of Sodium‐Proton Exchanger NHE1: Implications for Migraine The Faseb Journal. 32. DOI: 10.1096/Fasebj.2018.32.1_Supplement.533.60 |
0.752 |
|
2017 |
Sandweiss AJ, Cottier KE, McIntosh MI, Dussor G, Davis TP, Vanderah TW, Largent-Milnes TM. 17-β-Estradiol induces spreading depression and pain behavior in alert female rats. Oncotarget. 8: 114109-114122. PMID 29371973 DOI: 10.18632/Oncotarget.23141 |
0.79 |
|
2017 |
Malekzadeh P, Hu J, Sandweiss AJ, Ameli N, Bierny P, Largent-Milnes TM, Vanderah TW, Shirazi F. Effect of Centruroides antivenom on reversal of methamphetamine-induced hyperkinesis and hyperthermia in rats. Journal of Pharmaceutics & Pharmacology. 5. PMID 29354652 DOI: 10.13188/2327-204X.1000020 |
0.765 |
|
2017 |
Moutal A, Wang Y, Yang X, Ji Y, Luo S, Dorame A, Bellampalli SS, Chew LA, Cai S, Dustrude ET, Keener JE, Marty MT, Vanderah TW, Khanna R. Dissecting the role of the CRMP2-Neurofibromin complex on pain behaviors. Pain. PMID 28767512 DOI: 10.1097/J.Pain.0000000000001026 |
0.373 |
|
2017 |
Sandweiss AJ, Azim A, Ibraheem K, Largent-Milnes TM, Rhee P, Vanderah TW, Joseph B. Remote Ischemic Conditioning Preserves Cognition and Motor Coordination in a Mouse Model of Traumatic Brain Injury. The Journal of Trauma and Acute Care Surgery. PMID 28609381 DOI: 10.1097/Ta.0000000000001626 |
0.762 |
|
2017 |
Grenald SA, Doyle TM, Zhang H, Slosky LM, Chen Z, Largent-Milnes TM, Spiegel S, Vanderah TW, Salvemini D. Targeting the S1P/S1PR1 axis mitigates cancer-induced bone pain and neuroinflammation. Pain. PMID 28570482 DOI: 10.1097/J.Pain.0000000000000965 |
0.82 |
|
2017 |
Sandweiss AJ, McIntosh MI, Moutal A, Davidson-Knapp R, Hu J, Giri AK, Yamamoto T, Hruby VJ, Khanna R, Largent-Milnes TM, Vanderah TW. Genetic and pharmacological antagonism of NK1 receptor prevents opiate abuse potential. Molecular Psychiatry. PMID 28485408 DOI: 10.1038/Mp.2017.102 |
0.841 |
|
2017 |
Moutal A, Li W, Wang Y, Ju W, Luo S, Cai S, François-Moutal L, Perez-Miller S, Hu J, Dustrude ET, Vanderah TW, Gokhale V, Khanna M, Khanna R. Homology-guided mutational analysis reveals the functional requirements for antinociceptive specificity of CRMP2-derived peptides. British Journal of Pharmacology. PMID 28161890 DOI: 10.1111/Bph.13737 |
0.41 |
|
2017 |
Ibrahim MM, Patwardhan A, Gilbraith KB, Moutal A, Yang X, Chew LA, Largent-Milnes T, Malan TP, Vanderah TW, Porreca F, Khanna R. Long-lasting antinociceptive effects of green light in acute and chronic pain in rats. Pain. 158: 347-360. PMID 28092651 DOI: 10.1097/J.Pain.0000000000000767 |
0.819 |
|
2017 |
Zhang H, Doyle T, Grenald S, Jacobson K, Salvemini D, Vanderah T. (192) Targeting A3 adenosine receptor in HIV-1 gp120-induced neuropathic pain The Journal of Pain. 18: S24. DOI: 10.1016/J.Jpain.2017.02.099 |
0.37 |
|
2017 |
Cottier K, Galoway E, Kim J, Vanderah T, Davis T, Largent-Milnes T. (143) Transient Decreases in Blood-Brain Barrier Integrity Correspond with Facial Allodynia Duration in a Model of Migraine with Aura The Journal of Pain. 18: S12. DOI: 10.1016/J.Jpain.2017.02.049 |
0.761 |
|
2016 |
Grenald SA, Young MA, Wang Y, Ossipov MH, Ibrahim MM, Largent-Milnes TM, Vanderah TW. Synergistic attenuation of chronic pain using mu opioid and cannabinoid receptor 2 agonists. Neuropharmacology. PMID 28007501 DOI: 10.1016/J.Neuropharm.2016.12.008 |
0.827 |
|
2016 |
Ramos-Colon CN, Lee YS, Remesic MV, Hall SM, LaVigne J, Davis P, Sandweiss AJ, McIntosh MI, Hanson J, Largent-Milnes TM, Vanderah TW, Streicher JM, Porreca F, Hruby VJ. Structure Activity Relationships of [des-Arg(7)]- Dynorphin A Analogues at the Kappa Opioid Receptor. Journal of Medicinal Chemistry. PMID 27797517 DOI: 10.1021/Acs.Jmedchem.6B01411 |
0.823 |
|
2016 |
Forte BL, Slosky LM, Zhang H, Arnold M, Staatz WD, Hay M, Largent-Milnes TM, Vanderah TW. Angiotensin-(1-7)/Mas Receptor as an Antinociceptive Agent in Cancer-Induced Bone Pain. Pain. PMID 27541850 DOI: 10.1097/J.Pain.0000000000000690 |
0.834 |
|
2016 |
Xie JY, Chew LA, Yang X, Wang Y, Qu C, Wang Y, Federici LM, Fitz SD, Ripsch MS, Due MR, Moutal A, Khanna M, White FA, Vanderah TW, Johnson PL, et al. Sustained relief of ongoing experimental neuropathic pain by a CRMP2 peptide aptamer with low abuse potential. Pain. 157: 2124-2140. PMID 27537210 DOI: 10.1097/J.Pain.0000000000000628 |
0.703 |
|
2016 |
Slosky LM, BassiriRad NM, Symons AM, Thompson M, Doyle T, Forte BL, Staatz WD, Bui L, Neumann WL, Mantyh PW, Salvemini D, Largent-Milnes TM, Vanderah TW. The Cystine/Glutamate Antiporter System xc- Drives Breast Tumor Cell Glutamate Release and Cancer-Induced Bone Pain. Pain. PMID 27482630 DOI: 10.1097/J.Pain.0000000000000681 |
0.792 |
|
2016 |
Hanlon KE, Lozano-Ondoua AN, Umaretiya PJ, Symons-Liguori AM, Chandramouli A, Moy JK, Kwass WK, Mantyh PW, Nelson MA, Vanderah TW. Modulation of breast cancer cell viability by a cannabinoid receptor 2 agonist, JWH-015, is calcium dependent. Breast Cancer (Dove Medical Press). 8: 59-71. PMID 27186076 DOI: 10.2147/BCTT.S100393 |
0.758 |
|
2016 |
Moutal A, Chew LA, Yang X, Wang Y, Yeon SK, Telemi E, Meroueh S, Park KD, Shrinivasan R, Gilbraith KB, Qu C, Xie JY, Patwardhan A, Vanderah TW, Khanna M, et al. (S)-Lacosamide inhibition of CRMP2 phosphorylation reduces postoperative and neuropathic pain behaviors through distinct classes of sensory neurons identified by constellation pharmacology. Pain. PMID 26967696 DOI: 10.1097/J.Pain.0000000000000555 |
0.678 |
|
2015 |
Deekonda S, Rankin D, Davis P, Lai J, Vanderah TW, Porecca F, Hruby VJ. Design synthesis and structure-activity relationship of 5-substituted (tetrahydronaphthalen-2yl)methyl with N-phenyl-N-(piperidin-2-yl)propionamide derivatives as opioid ligands. Bioorganic & Medicinal Chemistry. PMID 26712115 DOI: 10.1016/J.Bmc.2015.11.030 |
0.62 |
|
2015 |
Deekonda S, Cole J, Sunna S, Rankin D, Largent-Milnes TM, Davis P, BassiriRad NM, Lai J, Vanderah TW, Porecca F, Hruby VJ. Enkephalin analogues with N-phenyl-N-(piperidin-2-ylmethyl)propionamide derivatives: Synthesis and biological evaluations. Bioorganic & Medicinal Chemistry Letters. PMID 26611918 DOI: 10.1016/J.Bmcl.2015.10.081 |
0.818 |
|
2015 |
Giri AK, Apostol CR, Wang Y, Forte BL, Largent-Milnes TM, Davis P, Rankin D, Molnar G, Olson KM, Porreca F, Vanderah TW, Hruby VJ. Discovery of Novel Multifunctional Ligands with μ/δ Opioid Agonist/Neurokinin-1 (NK1) Antagonist Activities for the Treatment of Pain. Journal of Medicinal Chemistry. PMID 26465170 DOI: 10.1021/Acs.Jmedchem.5B01170 |
0.799 |
|
2015 |
Sandweiss AJ, Vanderah TW. The pharmacology of neurokinin receptors in addiction: prospects for therapy. Substance Abuse and Rehabilitation. 6: 93-102. PMID 26379454 DOI: 10.2147/Sar.S70350 |
0.756 |
|
2015 |
Slosky LM, Largent-Milnes TM, Vanderah TW. Use of Animal Models in Understanding Cancer-induced Bone Pain. Cancer Growth and Metastasis. 8: 47-62. PMID 26339191 DOI: 10.4137/CGM.S21215 |
0.814 |
|
2015 |
Deekonda S, Wugalter L, Rankin D, Largent-Milnes TM, Davis P, Wang Y, Bassirirad NM, Lai J, Kulkarni V, Vanderah TW, Porreca F, Hruby VJ. Design and synthesis of novel bivalent ligands (MOR and DOR) by conjugation of enkephalin analogues with 4-anilidopiperidine derivatives. Bioorganic & Medicinal Chemistry Letters. PMID 26323872 DOI: 10.1016/J.Bmcl.2015.07.064 |
0.82 |
|
2015 |
Deekonda S, Wugalter L, Kulkarni V, Rankin D, Largent-Milnes TM, Davis P, Bassirirad NM, Lai J, Vanderah TW, Porreca F, Hruby VJ. Discovery of 5-substituted tetrahydronaphthalen-2yl-methyl with N-phenyl-N-(piperidin-4-yl)propionamide derivatives as potent opioid receptor ligands. Bioorganic & Medicinal Chemistry. 23: 6185-94. PMID 26299827 DOI: 10.1016/J.Bmc.2015.07.071 |
0.823 |
|
2015 |
Lee YS, Hall SM, Ramos-Colon C, Remesic M, Rankin D, Vanderah TW, Porreca F, Lai J, Hruby VJ. Blockade of non-opioid excitatory effects of spinal dynorphin A at bradykinin receptors. Receptors & Clinical Investigation. 2. PMID 26221618 DOI: 10.14800/Rci.517 |
0.771 |
|
2015 |
Nair P, Yamamoto T, Cowell S, Kulkarni V, Moye S, Navratilova E, Davis P, Ma SW, Vanderah TW, Lai J, Porreca F, Hruby VJ. Discovery of tripeptide-derived multifunctional ligands possessing delta/mu opioid receptor agonist and neurokinin 1 receptor antagonist activities. Bioorganic & Medicinal Chemistry Letters. 25: 3716-20. PMID 26212775 DOI: 10.1016/J.Bmcl.2015.06.030 |
0.789 |
|
2015 |
Ford A, Castonguay A, Cottet M, Little JW, Chen Z, Symons-Liguori AM, Doyle T, Egan TM, Vanderah TW, De Konnick Y, Tosh DK, Jacobson KA, Salvemini D. Engagement of the GABA to KCC2 signaling pathway contributes to the analgesic effects of A3AR agonists in neuropathic pain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 6057-67. PMID 25878279 DOI: 10.1523/Jneurosci.4495-14.2015 |
0.426 |
|
2015 |
François-Moutal L, Wang Y, Moutal A, Cottier KE, Melemedjian OK, Yang X, Wang Y, Ju W, Largent-Milnes TM, Khanna M, Vanderah TW, Khanna R. A membrane-delimited N-myristoylated CRMP2 peptide aptamer inhibits CaV2.2 trafficking and reverses inflammatory and postoperative pain behaviors. Pain. 156: 1247-64. PMID 25782368 DOI: 10.1097/j.pain.0000000000000147 |
0.791 |
|
2015 |
Slosky LM, Vanderah TW. Therapeutic potential of peroxynitrite decomposition catalysts: a patent review. Expert Opinion On Therapeutic Patents. 25: 443-66. PMID 25576197 DOI: 10.1517/13543776.2014.1000862 |
0.751 |
|
2015 |
Dzierlenga AL, Clarke JD, Hargraves TL, Ainslie GR, Vanderah TW, Paine MF, Cherrington NJ. Mechanistic basis of altered morphine disposition in nonalcoholic steatohepatitis. The Journal of Pharmacology and Experimental Therapeutics. 352: 462-70. PMID 25512370 DOI: 10.1124/Jpet.114.220764 |
0.351 |
|
2015 |
Little JW, Ford A, Symons-Liguori AM, Chen Z, Janes K, Doyle T, Xie J, Luongo L, Tosh DK, Maione S, Bannister K, Dickenson AH, Vanderah TW, Porreca F, Jacobson KA, et al. Endogenous adenosine A3 receptor activation selectively alleviates persistent pain states. Brain : a Journal of Neurology. 138: 28-35. PMID 25414036 DOI: 10.1093/Brain/Awu330 |
0.744 |
|
2015 |
Wang Y, Francois-Moutal L, Moutal A, Cottier K, Melemedjian O, Khanna M, Vanderah T, Khanna R. (399) A membrane-delimited N-myristoylated CRMP2 peptide aptamer inhibits CaV2.2 trafficking and reverses post-operative pain behaviors The Journal of Pain. 16: S75. DOI: 10.1016/J.Jpain.2015.01.318 |
0.797 |
|
2015 |
Grenald S, Wang Y, Young M, Stark J, Hu J, Vanderah T. (368) Synergistic drug interaction between morphine and a cannabinoid receptor 2 agonist in a model of neuropathic pain The Journal of Pain. 16: S68. DOI: 10.1016/j.jpain.2015.01.287 |
0.49 |
|
2015 |
Sandweiss A, Skinner D, Vanderah T, Largent-Milnes T. (354) Estrogen induces cortical spreading depression (CSD) associated with migraine aura in awake, freely moving female rats The Journal of Pain. 16: S64. DOI: 10.1016/J.Jpain.2015.01.272 |
0.765 |
|
2015 |
Slosky L, BassiriRad N, Symons-Liguori A, Forte B, Bui L, Largent-Milnes T, Vanderah T. (277) The cystine-glutamate antiporter system xc- drives tumor cell glutamate release and cancer-induced bone pain The Journal of Pain. 16: S45. DOI: 10.1016/J.Jpain.2015.01.195 |
0.797 |
|
2015 |
Deekonda S, Wugalter L, Kulkarni V, Rankin D, Largent-Milnes TM, Davis P, Bassirirad NM, Lai J, Vanderah TW, Porreca F, Hruby VJ. Discovery of 5-substituted tetrahydronaphthalen-2yl-methyl with N-phenyl-N-(piperidin-4-yl)propionamide derivatives as potent opioid receptor ligands Bioorganic and Medicinal Chemistry. 23: 6185-6194. DOI: 10.1016/j.bmc.2015.07.071 |
0.802 |
|
2015 |
King T, Porreca F, Vanderah TW. Opioid-induced hyperalgesia and cancer pain: Effects on tumor growth and disease progression Cancer Pain: From Molecules to Suffering. |
0.341 |
|
2014 |
Grenald SA, Largent-Milnes TM, Vanderah TW. Animal models for opioid addiction drug discovery. Expert Opinion On Drug Discovery. 9: 1345-54. PMID 25307021 DOI: 10.1517/17460441.2014.966076 |
0.793 |
|
2014 |
Lee YS, Muthu D, Hall SM, Ramos-Colon C, Rankin D, Hu J, Sandweiss AJ, De Felice M, Xie JY, Vanderah TW, Porreca F, Lai J, Hruby VJ. Discovery of amphipathic dynorphin A analogues to inhibit the neuroexcitatory effects of dynorphin A through bradykinin receptors in the spinal cord. Journal of the American Chemical Society. 136: 6608-16. PMID 24742335 DOI: 10.1021/Ja501677Q |
0.826 |
|
2013 |
Podolsky AT, Sandweiss A, Hu J, Bilsky EJ, Cain JP, Kumirov VK, Lee YS, Hruby VJ, Vardanyan RS, Vanderah TW. Novel fentanyl-based dual μ/δ-opioid agonists for the treatment of acute and chronic pain. Life Sciences. 93: 1010-6. PMID 24084045 DOI: 10.1016/J.Lfs.2013.09.016 |
0.834 |
|
2013 |
Lozano-Ondoua AN, Symons-Liguori AM, Vanderah TW. Cancer-induced bone pain: Mechanisms and models. Neuroscience Letters. 557: 52-9. PMID 24076008 DOI: 10.1016/j.neulet.2013.08.003 |
0.424 |
|
2013 |
Slosky LM, Thompson BJ, Sanchez-Covarrubias L, Zhang Y, Laracuente ML, Vanderah TW, Ronaldson PT, Davis TP. Acetaminophen modulates P-glycoprotein functional expression at the blood-brain barrier by a constitutive androstane receptor-dependent mechanism. Molecular Pharmacology. 84: 774-86. PMID 24019224 DOI: 10.1124/Mol.113.086298 |
0.817 |
|
2013 |
Nair P, Yamamoto T, Largent-Milnes TM, Cowell S, Kulkarni V, Moye S, Navratilova E, Davis P, Ma SW, Vanderah TW, Lai J, Porreca F, Hruby VJ. Truncation of the peptide sequence in bifunctional ligands with mu and delta opioid receptor agonist and neurokinin 1 receptor antagonist activities. Bioorganic & Medicinal Chemistry Letters. 23: 4975-8. PMID 23899615 DOI: 10.1016/J.Bmcl.2013.06.065 |
0.817 |
|
2013 |
Largent-Milnes TM, Brookshire SW, Skinner DP, Hanlon KE, Giuvelis D, Yamamoto T, Davis P, Campos CR, Nair P, Deekonda S, Bilsky EJ, Porreca F, Hruby VJ, Vanderah TW. Building a better analgesic: multifunctional compounds that address injury-induced pathology to enhance analgesic efficacy while eliminating unwanted side effects. The Journal of Pharmacology and Experimental Therapeutics. 347: 7-19. PMID 23860305 DOI: 10.1124/Jpet.113.205245 |
0.848 |
|
2013 |
Petrov RR, Lee YS, Vardanyan RS, Liu L, Ma SW, Davis P, Lai J, Porreca F, Vanderah TW, Hruby VJ. Effect of anchoring 4-anilidopiperidines to opioid peptides. Bioorganic & Medicinal Chemistry Letters. 23: 3434-7. PMID 23623418 DOI: 10.1016/J.Bmcl.2013.03.065 |
0.69 |
|
2013 |
Lozano-Ondoua AN, Hanlon KE, Symons-Liguori AM, Largent-Milnes TM, Havelin JJ, Ferland HL, Chandramouli A, Owusu-Ankomah M, Nikolich-Zugich T, Bloom AP, Jimenez-Andrade JM, King T, Porreca F, Nelson MA, Mantyh PW, ... Vanderah TW, et al. Disease modification of breast cancer-induced bone remodeling by cannabinoid 2 receptor agonists. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 28: 92-107. PMID 22903605 DOI: 10.1002/Jbmr.1732 |
0.82 |
|
2013 |
Symons-Liguori AM, Vanderah TW. The delta opioid receptor Acs Symposium Series. 1131: 223-244. DOI: 10.1021/bk-2013-1131.ch012 |
0.324 |
|
2012 |
Edelmayer RM, Le LN, Yan J, Wei X, Nassini R, Materazzi S, Preti D, Appendino G, Geppetti P, Dodick DW, Vanderah TW, Porreca F, Dussor G. Activation of TRPA1 on dural afferents: a potential mechanism of headache pain. Pain. 153: 1949-58. PMID 22809691 DOI: 10.1016/J.Pain.2012.06.012 |
0.779 |
|
2012 |
Tumati S, Largent-Milnes TM, Keresztes AI, Yamamoto T, Vanderah TW, Roeske WR, Hruby VJ, Varga EV. Tachykinin NKâ‚ receptor antagonist co-administration attenuates opioid withdrawal-mediated spinal microglia and astrocyte activation. European Journal of Pharmacology. 684: 64-70. PMID 22724132 DOI: 10.1016/J.Ejphar.2012.03.025 |
0.822 |
|
2012 |
De Felice M, Melchiorri P, Ossipov MH, Vanderah TW, Porreca F, Negri L. Mechanisms of Bv8-induced biphasic hyperalgesia: increased excitatory transmitter release and expression. Neuroscience Letters. 521: 40-5. PMID 22641053 DOI: 10.1016/j.neulet.2012.05.055 |
0.553 |
|
2012 |
Pajouhesh H, Feng ZP, Zhang L, Pajouhesh H, Jiang X, Hendricson A, Dong H, Tringham E, Ding Y, Vanderah TW, Porreca F, Belardetti F, Zamponi GW, Mitscher LA, Snutch TP. Structure-activity relationships of trimethoxybenzyl piperazine N-type calcium channel inhibitors. Bioorganic & Medicinal Chemistry Letters. 22: 4153-8. PMID 22579422 DOI: 10.1016/J.Bmcl.2012.04.054 |
0.499 |
|
2012 |
Tumati S, Largent-Milnes TM, Keresztes A, Ren J, Roeske WR, Vanderah TW, Varga EV. Repeated morphine treatment-mediated hyperalgesia, allodynia and spinal glial activation are blocked by co-administration of a selective cannabinoid receptor type-2 agonist. Journal of Neuroimmunology. 244: 23-31. PMID 22285397 DOI: 10.1016/J.Jneuroim.2011.12.021 |
0.814 |
|
2012 |
Marshall TM, Herman DS, Largent-Milnes TM, Badghisi H, Zuber K, Holt SC, Lai J, Porreca F, Vanderah TW. Activation of descending pain-facilitatory pathways from the rostral ventromedial medulla by cholecystokinin elicits release of prostaglandin-Eâ‚‚ in the spinal cord. Pain. 153: 86-94. PMID 22030324 DOI: 10.1016/J.Pain.2011.09.021 |
0.808 |
|
2012 |
Ondoua A, Rodriquez J, Hanlon K, Havelin J, Bilsky E, Holsinger L, Booth R, Vanderah T. Multivalent cathepsin inhibitor, VBY-825, attenuates breast-cancer induced bone remodeling and pain The Journal of Pain. 13: S43. DOI: 10.1016/J.Jpain.2012.01.182 |
0.768 |
|
2011 |
Sukhtankar D, Okun A, Chandramouli A, Nelson MA, Vanderah TW, Cress AE, Porreca F, King T. Inhibition of p38-MAPK signaling pathway attenuates breast cancer induced bone pain and disease progression in a murine model of cancer-induced bone pain. Molecular Pain. 7: 81. PMID 22014040 DOI: 10.1186/1744-8069-7-81 |
0.815 |
|
2011 |
Vardanyan R, Kumirov VK, Nichol GS, Davis P, Liktor-Busa E, Rankin D, Varga E, Vanderah T, Porreca F, Lai J, Hruby VJ. Synthesis and biological evaluation of new opioid agonist and neurokinin-1 antagonist bivalent ligands. Bioorganic & Medicinal Chemistry. 19: 6135-42. PMID 21925887 DOI: 10.1016/J.Bmc.2011.08.027 |
0.673 |
|
2011 |
De Felice M, Sanoja R, Wang R, Vera-Portocarrero L, Oyarzo J, King T, Ossipov MH, Vanderah TW, Lai J, Dussor GO, Fields HL, Price TJ, Porreca F. Engagement of descending inhibition from the rostral ventromedial medulla protects against chronic neuropathic pain. Pain. 152: 2701-9. PMID 21745713 DOI: 10.1016/J.Pain.2011.06.008 |
0.786 |
|
2011 |
Fioravanti B, Kasasbeh A, Edelmayer R, Skinner DP, Hartings JA, Burklund RD, De Felice M, French ED, Dussor GO, Dodick DW, Porreca F, Vanderah TW. Evaluation of cutaneous allodynia following induction of cortical spreading depression in freely moving rats. Cephalalgia : An International Journal of Headache. 31: 1090-100. PMID 21700643 DOI: 10.1177/0333102411410609 |
0.751 |
|
2011 |
Tumati S, Roeske WR, Largent-Milnes TM, Vanderah TW, Varga EV. Intrathecal PKA-selective siRNA treatment blocks sustained morphine-mediated pain sensitization and antinociceptive tolerance in rats. Journal of Neuroscience Methods. 199: 62-8. PMID 21571003 DOI: 10.1016/J.Jneumeth.2011.04.036 |
0.821 |
|
2011 |
Hanlon KE, Herman DS, Agnes RS, Largent-Milnes TM, Kumarasinghe IR, Ma SW, Guo W, Lee YS, Ossipov MH, Hruby VJ, Lai J, Porreca F, Vanderah TW. Novel peptide ligands with dual acting pharmacophores designed for the pathophysiology of neuropathic pain. Brain Research. 1395: 1-11. PMID 21550594 DOI: 10.1016/J.Brainres.2011.04.024 |
0.849 |
|
2011 |
Stagg NJ, Mata HP, Ibrahim MM, Henriksen EJ, Porreca F, Vanderah TW, Philip Malan T. Regular exercise reverses sensory hypersensitivity in a rat neuropathic pain model: role of endogenous opioids. Anesthesiology. 114: 940-8. PMID 21386701 DOI: 10.1097/Aln.0B013E318210F880 |
0.582 |
|
2011 |
Yamamoto T, Nair P, Largent-Milnes TM, Jacobsen NE, Davis P, Ma SW, Yamamura HI, Vanderah TW, Porreca F, Lai J, Hruby VJ. Discovery of a potent and efficacious peptide derivative for δ/μ opioid agonist/neurokinin 1 antagonist activity with a 2',6'-dimethyl-L-tyrosine: in vitro, in vivo, and NMR-based structural studies. Journal of Medicinal Chemistry. 54: 2029-38. PMID 21366266 DOI: 10.1021/Jm101023R |
0.821 |
|
2011 |
Lee YS, Kulkarani V, Cowell SM, Ma SW, Davis P, Hanlon KE, Vanderah TW, Lai J, Porreca F, Vardanyan R, Hruby VJ. Development of potent μ and δ opioid agonists with high lipophilicity. Journal of Medicinal Chemistry. 54: 382-6. PMID 21128594 DOI: 10.1021/Jm100982D |
0.821 |
|
2011 |
Holsinger LJ, Ondoua-Lozano A, Rodriguez J, Hanlon K, Bilsky EJ, Havelin J, Dener JM, Booth R, Vanderah TW. Abstract A219: Efficacy of a spectrum-selective cathepsin inhibitor in a mouse model of bone cancer. Molecular Cancer Therapeutics. 10. DOI: 10.1158/1535-7163.Targ-11-A219 |
0.759 |
|
2011 |
Ondoua A, Hanlon K, Largent-Milnes T, Sukhtankar D, King T, Mantyh P, Vanderah T. CB2 receptor agonists act as a disease-modifying treatment by attenuating breast cancer-induced bone pain and improving bone health in a murine model of breast cancer metastases The Journal of Pain. 12: P51. DOI: 10.1016/J.Jpain.2011.02.207 |
0.795 |
|
2010 |
Hanlon KE, Vanderah TW. Constitutive activity at the cannabinoid CB(1) receptor and behavioral responses. Methods in Enzymology. 484: 3-30. PMID 21036224 DOI: 10.1016/B978-0-12-381298-8.00001-0 |
0.776 |
|
2010 |
Largent-Milnes TM, Yamamoto T, Nair P, Moulton JW, Hruby VJ, Lai J, Porreca F, Vanderah TW. Spinal or systemic TY005, a peptidic opioid agonist/neurokinin 1 antagonist, attenuates pain with reduced tolerance. British Journal of Pharmacology. 161: 986-1001. PMID 20977451 DOI: 10.1111/J.1476-5381.2010.00824.X |
0.854 |
|
2010 |
Tumati S, Roeske WR, Vanderah TW, Varga EV. Sustained morphine treatment augments prostaglandin E2-evoked calcitonin gene-related peptide release from primary sensory neurons in a PKA-dependent manner. European Journal of Pharmacology. 648: 95-101. PMID 20826131 DOI: 10.1016/j.ejphar.2010.08.042 |
0.413 |
|
2010 |
Tumati S, Roeske WR, Largent-Milnes T, Wang R, Vanderah TW, Varga EV. Sustained morphine-mediated pain sensitization and antinociceptive tolerance are blocked by intrathecal treatment with Raf-1-selective siRNA. British Journal of Pharmacology. 161: 51-64. PMID 20718739 DOI: 10.1111/J.1476-5381.2010.00869.X |
0.84 |
|
2010 |
Yamamoto T, Nair P, Jacobsen NE, Kulkarni V, Davis P, Ma SW, Navratilova E, Yamamura HI, Vanderah TW, Porreca F, Lai J, Hruby VJ. Biological and conformational evaluation of bifunctional compounds for opioid receptor agonists and neurokinin 1 receptor antagonists possessing two penicillamines. Journal of Medicinal Chemistry. 53: 5491-501. PMID 20617791 DOI: 10.1021/Jm100157M |
0.836 |
|
2010 |
De Felice M, Ossipov MH, Wang R, Lai J, Chichorro J, Meng I, Dodick DW, Vanderah TW, Dussor G, Porreca F. Triptan-induced latent sensitization: a possible basis for medication overuse headache. Annals of Neurology. 67: 325-37. PMID 20373344 DOI: 10.1002/Ana.21897 |
0.727 |
|
2010 |
Largent-Milnes TM, Vanderah TW. Recently patented and promising ORL-1 ligands: where have we been and where are we going? Expert Opinion On Therapeutic Patents. 20: 291-305. PMID 20180617 DOI: 10.1517/13543771003602004 |
0.817 |
|
2010 |
Lozano-Ondoua AN, Wright C, Vardanyan A, King T, Largent-Milnes TM, Nelson M, Jimenez-Andrade JM, Mantyh PW, Vanderah TW. A cannabinoid 2 receptor agonist attenuates bone cancer-induced pain and bone loss. Life Sciences. 86: 646-53. PMID 20176037 DOI: 10.1016/J.Lfs.2010.02.014 |
0.816 |
|
2010 |
Pajouhesh H, Feng ZP, Ding Y, Zhang L, Pajouhesh H, Morrison JL, Belardetti F, Tringham E, Simonson E, Vanderah TW, Porreca F, Zamponi GW, Mitscher LA, Snutch TP. Structure-activity relationships of diphenylpiperazine N-type calcium channel inhibitors. Bioorganic & Medicinal Chemistry Letters. 20: 1378-83. PMID 20117000 DOI: 10.1016/J.Bmcl.2010.01.008 |
0.477 |
|
2010 |
Vanderah TW. Delta and kappa opioid receptors as suitable drug targets for pain. The Clinical Journal of Pain. 26: S10-5. PMID 20026960 DOI: 10.1097/AJP.0b013e3181c49e3a |
0.534 |
|
2010 |
Jimenez-Andrade JM, Mantyh WG, Bloom AP, Xu H, Ferng AS, Dussor G, Vanderah TW, Mantyh PW. A phenotypically restricted set of primary afferent nerve fibers innervate the bone versus skin: therapeutic opportunity for treating skeletal pain. Bone. 46: 306-13. PMID 19766746 DOI: 10.1016/J.Bone.2009.09.013 |
0.34 |
|
2010 |
King T, Vera-Portocarrero L, Gutierrez T, Vanderah TW, Dussor G, Lai J, Fields HL, Porreca F. Erratum: Corrigendum: Unmasking the tonic-aversive state in neuropathic pain Nature Neuroscience. 13: 1033-1033. DOI: 10.1038/Nn0810-1033B |
0.688 |
|
2009 |
Yamamoto T, Nair P, Jacobsen NE, Vagner J, Kulkarni V, Davis P, Ma SW, Navratilova E, Yamamura HI, Vanderah TW, Porreca F, Lai J, Hruby VJ. Improving metabolic stability by glycosylation: bifunctional peptide derivatives that are opioid receptor agonists and neurokinin 1 receptor antagonists. Journal of Medicinal Chemistry. 52: 5164-75. PMID 20560643 DOI: 10.1021/Jm900473P |
0.804 |
|
2009 |
King T, Vera-Portocarrero L, Gutierrez T, Vanderah TW, Dussor G, Lai J, Fields HL, Porreca F. Unmasking the tonic-aversive state in neuropathic pain. Nature Neuroscience. 12: 1364-6. PMID 19783992 DOI: 10.1038/Nn.2407 |
0.701 |
|
2009 |
Yamamoto T, Nair P, Ma SW, Davis P, Yamamura HI, Vanderah TW, Porreca F, Lai J, Hruby VJ. The biological activity and metabolic stability of peptidic bifunctional compounds that are opioid receptor agonists and neurokinin-1 receptor antagonists with a cystine moiety. Bioorganic & Medicinal Chemistry. 17: 7337-43. PMID 19762245 DOI: 10.1016/J.Bmc.2009.08.035 |
0.746 |
|
2009 |
Vardanyan R, Vijay G, Nichol GS, Liu L, Kumarasinghe I, Davis P, Vanderah T, Porreca F, Lai J, Hruby VJ. Synthesis and investigations of double-pharmacophore ligands for treatment of chronic and neuropathic pain. Bioorganic & Medicinal Chemistry. 17: 5044-53. PMID 19540763 DOI: 10.1016/J.Bmc.2009.05.065 |
0.721 |
|
2009 |
Tumati S, Yamamura HI, Vanderah TW, Roeske WR, Varga EV. Sustained morphine treatment augments capsaicin-evoked calcitonin gene-related peptide release from primary sensory neurons in a protein kinase A- and Raf-1-dependent manner. The Journal of Pharmacology and Experimental Therapeutics. 330: 810-7. PMID 19491327 DOI: 10.1124/jpet.109.151704 |
0.621 |
|
2009 |
Nair P, Yamamoto T, Kulkarni V, Moye S, Navratilova E, Davis P, Largent T, Ma SW, Yamamura HI, Vanderah T, Lai J, Porreca F, Hruby VJ. Novel bifunctional peptides as opioid agonists and NK-1 antagonists. Advances in Experimental Medicine and Biology. 611: 537-8. PMID 19400302 DOI: 10.1007/978-0-387-73657-0_235 |
0.84 |
|
2009 |
Lee Y, Petrov R, Kulkarni V, Min BJ, Ma SW, Davis P, Oyarzo J, Vanderah T, Lai J, Porreca F, Vardanyan R, Hruby VJ. Development of mu/delta opioid ligands: enkephalin analogues containing 4-anilidopiperidine moiety. Advances in Experimental Medicine and Biology. 611: 517-8. PMID 19400292 DOI: 10.1007/978-0-387-73657-0_225 |
0.69 |
|
2009 |
Tumati S, Yamamura HI, St John PA, Vanderah TW, Roeske WR, Varga EV. Sustained cannabinoid agonist treatment augments CGRP release in a PKA-dependent manner. Neuroreport. 20: 815-9. PMID 19387418 DOI: 10.1097/WNR.0b013e32832be50b |
0.587 |
|
2009 |
Edelmayer RM, Vanderah TW, Majuta L, Zhang ET, Fioravanti B, De Felice M, Chichorro JG, Ossipov MH, King T, Lai J, Kori SH, Nelsen AC, Cannon KE, Heinricher MM, Porreca F. Medullary pain facilitating neurons mediate allodynia in headache-related pain. Annals of Neurology. 65: 184-93. PMID 19259966 DOI: 10.1002/Ana.21537 |
0.837 |
|
2009 |
Porreca F, Vanderah TW. Spring pain research conference 2008. Brain Research Reviews. 60: 1. PMID 19150467 DOI: 10.1016/j.brainresrev.2008.12.022 |
0.534 |
|
2009 |
Stein C, Clark JD, Oh U, Vasko MR, Wilcox GL, Overland AC, Vanderah TW, Spencer RH. Peripheral mechanisms of pain and analgesia. Brain Research Reviews. 60: 90-113. PMID 19150465 DOI: 10.1016/J.Brainresrev.2008.12.017 |
0.438 |
|
2009 |
Zhang W, Gardell S, Zhang D, Xie JY, Agnes RS, Badghisi H, Hruby VJ, Rance N, Ossipov MH, Vanderah TW, Porreca F, Lai J. Neuropathic pain is maintained by brainstem neurons co-expressing opioid and cholecystokinin receptors. Brain : a Journal of Neurology. 132: 778-87. PMID 19050032 DOI: 10.1093/Brain/Awn330 |
0.797 |
|
2009 |
Vardanyan A, Wang R, Vanderah TW, Ossipov MH, Lai J, Porreca F, King T. TRPV1 receptor in expression of opioid-induced hyperalgesia. The Journal of Pain : Official Journal of the American Pain Society. 10: 243-52. PMID 18774343 DOI: 10.1016/J.Jpain.2008.07.004 |
0.846 |
|
2008 |
Fioravanti B, Vanderah TW. The ORL-1 receptor system: are there opportunities for antagonists in pain therapy? Current Topics in Medicinal Chemistry. 8: 1442-51. PMID 18991730 DOI: 10.2174/156802608786264227 |
0.519 |
|
2008 |
Fioravanti B, De Felice M, Stucky CL, Medler KA, Luo MC, Gardell LR, Ibrahim M, Malan TP, Yamamura HI, Ossipov MH, King T, Lai J, Porreca F, Vanderah TW. Constitutive activity at the cannabinoid CB1 receptor is required for behavioral response to noxious chemical stimulation of TRPV1: antinociceptive actions of CB1 inverse agonists. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 11593-602. PMID 18987195 DOI: 10.1523/Jneurosci.3322-08.2008 |
0.82 |
|
2008 |
Tumati S, Milnes TL, Yamamura HI, Vanderah TW, Roeske WR, Varga EV. Intrathecal Raf-1-selective siRNA attenuates sustained morphine-mediated thermal hyperalgesia. European Journal of Pharmacology. 601: 207-8. PMID 18976650 DOI: 10.1016/j.ejphar.2008.10.033 |
0.648 |
|
2008 |
Yamamoto T, Nair P, Jacobsen NE, Davis P, Ma SW, Navratilova E, Moye S, Lai J, Yamamura HI, Vanderah TW, Porreca F, Hruby VJ. The importance of micelle-bound states for the bioactivities of bifunctional peptide derivatives for delta/mu opioid receptor agonists and neurokinin 1 receptor antagonists. Journal of Medicinal Chemistry. 51: 6334-47. PMID 18821747 DOI: 10.1021/Jm800389V |
0.804 |
|
2008 |
Largent-Milnes TM, Guo W, Wang HY, Burns LH, Vanderah TW. Oxycodone plus ultra-low-dose naltrexone attenuates neuropathic pain and associated mu-opioid receptor-Gs coupling. The Journal of Pain : Official Journal of the American Pain Society. 9: 700-13. PMID 18468954 DOI: 10.1016/J.Jpain.2008.03.005 |
0.807 |
|
2008 |
Wang R, King T, Ossipov MH, Rossomando AJ, Vanderah TW, Harvey P, Cariani P, Frank E, Sah DW, Porreca F. Persistent restoration of sensory function by immediate or delayed systemic artemin after dorsal root injury. Nature Neuroscience. 11: 488-96. PMID 18344995 DOI: 10.1038/Nn2069 |
0.627 |
|
2008 |
Yue X, Tumati S, Navratilova E, Strop D, St John PA, Vanderah TW, Roeske WR, Yamamura HI, Varga EV. Sustained morphine treatment augments basal CGRP release from cultured primary sensory neurons in a Raf-1 dependent manner. European Journal of Pharmacology. 584: 272-7. PMID 18328477 DOI: 10.1016/J.Ejphar.2008.02.013 |
0.743 |
|
2008 |
Vanderah TW, Largent-Milnes T, Lai J, Porreca F, Houghten RA, Menzaghi F, Wisniewski K, Stalewski J, Sueiras-Diaz J, Galyean R, Schteingart C, Junien JL, Trojnar J, Rivière PJ. Novel D-amino acid tetrapeptides produce potent antinociception by selectively acting at peripheral kappa-opioid receptors. European Journal of Pharmacology. 583: 62-72. PMID 18282565 DOI: 10.1016/J.Ejphar.2008.01.011 |
0.828 |
|
2008 |
Yamamoto T, Nair P, Vagner J, Largent-Milnes T, Davis P, Ma SW, Navratilova E, Moye S, Tumati S, Lai J, Yamamura HI, Vanderah TW, Porreca F, Hruby VJ. A structure-activity relationship study and combinatorial synthetic approach of C-terminal modified bifunctional peptides that are delta/mu opioid receptor agonists and neurokinin 1 receptor antagonists. Journal of Medicinal Chemistry. 51: 1369-76. PMID 18266313 DOI: 10.1021/Jm070332F |
0.822 |
|
2008 |
Hruby VJ, Porreca F, Yamamura HI, Tollin G, Agnes RS, Lee YS, Cai M, Alves I, Cowell S, Varga E, Davis P, Salamon Z, Roeske W, Vanderah T, Lai J. New paradigms and tools in drug design for pain and addiction Drug Addiction: From Basic Research to Therapy. 477-494. DOI: 10.1007/978-0-387-76678-2_28 |
0.452 |
|
2007 |
King T, Vardanyan A, Majuta L, Melemedjian O, Nagle R, Cress AE, Vanderah TW, Lai J, Porreca F. Morphine treatment accelerates sarcoma-induced bone pain, bone loss, and spontaneous fracture in a murine model of bone cancer. Pain. 132: 154-68. PMID 17706870 DOI: 10.1016/J.Pain.2007.06.026 |
0.84 |
|
2007 |
King SH, Mayorov AV, Balse-Srinivasan P, Hruby VJ, Vanderah TW, Wessells H. Melanocortin receptors, melanotropic peptides and penile erection. Current Topics in Medicinal Chemistry. 7: 1098-1106. PMID 17584130 DOI: 10.2174/156802607780906564 |
0.39 |
|
2007 |
Yamamoto T, Nair P, Davis P, Ma SW, Navratilova E, Moye S, Tumati S, Lai J, Vanderah TW, Yamamura HI, Porreca F, Hruby VJ. Design, synthesis, and biological evaluation of novel bifunctional C-terminal-modified peptides for delta/mu opioid receptor agonists and neurokinin-1 receptor antagonists. Journal of Medicinal Chemistry. 50: 2779-86. PMID 17516639 DOI: 10.1021/Jm061369N |
0.83 |
|
2007 |
Vanderah TW. Pathophysiology of pain. The Medical Clinics of North America. 91: 1-12. PMID 17164100 DOI: 10.1016/j.mcna.2006.10.006 |
0.422 |
|
2007 |
Vera-Portocarrero LP, Zhang ET, King T, Ossipov MH, Vanderah TW, Lai J, Porreca F. Spinal NK-1 receptor expressing neurons mediate opioid-induced hyperalgesia and antinociceptive tolerance via activation of descending pathways. Pain. 129: 35-45. PMID 17123731 DOI: 10.1016/J.Pain.2006.09.033 |
0.716 |
|
2007 |
Fioravanti B, Ibrahim M, Luo M, DeFelice M, Zhang W, Medler K, Stucky C, Malan T, Ossipov M, Lai J, Porreca F, Vanderah T. (641) The Journal of Pain. 8: S11. DOI: 10.1016/j.jpain.2007.02.052 |
0.621 |
|
2006 |
Ndungu JM, Cain JP, Davis P, Ma SW, Vanderah TW, Lai J, Porreca F, Hruby VJ. Synthesis of constrained analogues of cholecystokinin/opioid chimeric peptides. Tetrahedron Letters. 47: 2233-2236. PMID 17203138 DOI: 10.1016/J.Tetlet.2006.01.096 |
0.679 |
|
2006 |
Hruby VJ, Porreca F, Yamamura HI, Tollin G, Agnes RS, Lee YS, Cai M, Alves I, Cowell S, Varga E, Davis P, Salamon Z, Roeske W, Vanderah T, Lai J. New paradigms and tools in drug design for pain and addiction. The Aaps Journal. 8: E450-60. PMID 17025262 DOI: 10.1208/Aapsj080353 |
0.769 |
|
2006 |
King T, Rao S, Vanderah T, Chen Q, Vardanyan A, Porreca F. Differential blockade of nerve injury-induced shift in weight bearing and thermal and tactile hypersensitivity by milnacipran. The Journal of Pain : Official Journal of the American Pain Society. 7: 513-20. PMID 16814690 DOI: 10.1016/J.Jpain.2006.02.001 |
0.736 |
|
2006 |
Negus SS, Vanderah TW, Brandt MR, Bilsky EJ, Becerra L, Borsook D. Preclinical assessment of candidate analgesic drugs: recent advances and future challenges. The Journal of Pharmacology and Experimental Therapeutics. 319: 507-14. PMID 16751251 DOI: 10.1124/Jpet.106.106377 |
0.425 |
|
2006 |
Yue X, Varga EV, Stropova D, Vanderah TW, Yamamura HI, Roeske WR. Chronic morphine-mediated adenylyl cyclase superactivation is attenuated by the Raf-1 inhibitor, GW5074. European Journal of Pharmacology. 540: 57-9. PMID 16750187 DOI: 10.1016/j.ejphar.2006.04.033 |
0.616 |
|
2006 |
Porreca F, Vanderah TW, Guo W, Barth M, Dodey P, Peyrou V, Luccarini JM, Junien JL, Pruneau D. Antinociceptive pharmacology of N-[[4-(4,5-dihydro-1H-imidazol-2-yl)phenyl]methyl]-2-[2-[[(4-methoxy-2,6-dimethylphenyl) sulfonyl]methylamino]ethoxy]-N-methylacetamide, fumarate (LF22-0542), a novel nonpeptidic bradykinin B1 receptor antagonist. The Journal of Pharmacology and Experimental Therapeutics. 318: 195-205. PMID 16565167 DOI: 10.1124/jpet.105.098368 |
0.583 |
|
2006 |
Ibrahim MM, Rude ML, Stagg NJ, Mata HP, Lai J, Vanderah TW, Porreca F, Buckley NE, Makriyannis A, Malan TP. CB2 cannabinoid receptor mediation of antinociception. Pain. 122: 36-42. PMID 16563625 DOI: 10.1016/J.Pain.2005.12.018 |
0.708 |
|
2006 |
Gardell LR, King T, Ossipov MH, Rice KC, Lai J, Vanderah TW, Porreca F. Opioid receptor-mediated hyperalgesia and antinociceptive tolerance induced by sustained opiate delivery. Neuroscience Letters. 396: 44-9. PMID 16343768 DOI: 10.1016/J.Neulet.2005.11.009 |
0.849 |
|
2006 |
Ibrahim M, Rude M, Stagg N, Mata H, Lai J, Vanderah T, Porreca F, Buckley N, Makriyannis A, Malan T. CB2 cannabinoid receptor mediation of antinociception Acute Pain. 8: 142. DOI: 10.1016/j.acpain.2006.08.026 |
0.653 |
|
2005 |
King T, Ossipov MH, Vanderah TW, Porreca F, Lai J. Is paradoxical pain induced by sustained opioid exposure an underlying mechanism of opioid antinociceptive tolerance? Neuro-Signals. 14: 194-205. PMID 16215302 DOI: 10.1159/000087658 |
0.767 |
|
2005 |
Navratilova E, Eaton MC, Stropova D, Varga EV, Vanderah TW, Roeske WR, Yamamura HI. Morphine promotes phosphorylation of the human delta-opioid receptor at serine 363. European Journal of Pharmacology. 519: 212-4. PMID 16135360 DOI: 10.1016/J.Ejphar.2005.07.024 |
0.735 |
|
2005 |
King T, Gardell LR, Wang R, Vardanyan A, Ossipov MH, Malan TP, Vanderah TW, Hunt SP, Hruby VJ, Lai J, Porreca F. Role of NK-1 neurotransmission in opioid-induced hyperalgesia. Pain. 116: 276-88. PMID 15964684 DOI: 10.1016/J.Pain.2005.04.014 |
0.846 |
|
2005 |
Ossipov MH, Lai J, King T, Vanderah TW, Porreca F. Underlying mechanisms of pronociceptive consequences of prolonged morphine exposure. Biopolymers. 80: 319-24. PMID 15795927 DOI: 10.1002/Bip.20254 |
0.758 |
|
2005 |
Ibrahim MM, Porreca F, Lai J, Albrecht PJ, Rice FL, Khodorova A, Davar G, Makriyannis A, Vanderah TW, Mata HP, Malan TP. CB2 cannabinoid receptor activation produces antinociception by stimulating peripheral release of endogenous opioids. Proceedings of the National Academy of Sciences of the United States of America. 102: 3093-8. PMID 15705714 DOI: 10.1073/Pnas.0409888102 |
0.727 |
|
2005 |
Varga EV, Hosohata K, Borys D, Navratilova E, Nylen A, Vanderah TW, Porreca F, Roeske WR, Yamamura HI. Antinociception depends on the presence of G protein gamma2-subunits in brain. European Journal of Pharmacology. 508: 93-8. PMID 15680258 DOI: 10.1016/J.Ejphar.2004.11.062 |
0.748 |
|
2005 |
Xie JY, Herman DS, Stiller CO, Gardell LR, Ossipov MH, Lai J, Porreca F, Vanderah TW. Cholecystokinin in the rostral ventromedial medulla mediates opioid-induced hyperalgesia and antinociceptive tolerance. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 409-16. PMID 15647484 DOI: 10.1523/Jneurosci.4054-04.2005 |
0.85 |
|
2005 |
Gavva NR, Tamir R, Qu Y, Klionsky L, Zhang TJ, Immke D, Wang J, Zhu D, Vanderah TW, Porreca F, Doherty EM, Norman MH, Wild KD, Bannon AW, Louis JC, et al. AMG 9810 [(E)-3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo[b][1,4] dioxin-6-yl)acrylamide], a novel vanilloid receptor 1 (TRPV1) antagonist with antihyperalgesic properties. The Journal of Pharmacology and Experimental Therapeutics. 313: 474-84. PMID 15615864 DOI: 10.1124/jpet.104.079855 |
0.58 |
|
2005 |
Vera-Portocarrero L, King T, Vanderah T, Lai J, Porreca F. Ablation of NK-1 expressing cells in the spinal dorsal horn prevents the development of opioid-induced hyperalgesia and antinociceptive tolerance The Journal of Pain. 6: S17. DOI: 10.1016/J.Jpain.2005.01.065 |
0.697 |
|
2004 |
Ossipov MH, Lai J, King T, Vanderah TW, Malan TP, Hruby VJ, Porreca F. Antinociceptive and nociceptive actions of opioids. Journal of Neurobiology. 61: 126-48. PMID 15362157 DOI: 10.1002/Neu.20091 |
0.749 |
|
2004 |
Chen Q, King T, Vanderah TW, Ossipov MH, Malan TP, Lai J, Porreca F. Differential blockade of nerve injury-induced thermal and tactile hypersensitivity by systemically administered brain-penetrating and peripherally restricted local anesthetics. The Journal of Pain : Official Journal of the American Pain Society. 5: 281-9. PMID 15219260 DOI: 10.1016/J.Jpain.2004.05.002 |
0.715 |
|
2004 |
Quartilho A, Mata HP, Ibrahim MM, Vanderah TW, Ossipov MH, Lai J, Porreca F, Malan TP. Production of paradoxical sensory hypersensitivity by alpha 2-adrenoreceptor agonists. Anesthesiology. 100: 1538-44. PMID 15166576 DOI: 10.1097/00000542-200406000-00029 |
0.698 |
|
2004 |
Gavva NR, Klionsky L, Qu Y, Shi L, Tamir R, Edenson S, Zhang TJ, Viswanadhan VN, Toth A, Pearce LV, Vanderah TW, Porreca F, Blumberg PM, Lile J, Sun Y, et al. Molecular determinants of vanilloid sensitivity in TRPV1. The Journal of Biological Chemistry. 279: 20283-95. PMID 14996838 DOI: 10.1074/Jbc.M312577200 |
0.506 |
|
2004 |
Vanderah TW, Schteingart CD, Trojnar J, Junien JL, Lai J, Riviere PJ. FE200041 (D-Phe-D-Phe-D-Nle-D-Arg-NH2): A peripheral efficacious kappa opioid agonist with unprecedented selectivity. The Journal of Pharmacology and Experimental Therapeutics. 310: 326-33. PMID 14993260 DOI: 10.1124/jpet.104.065391 |
0.664 |
|
2004 |
Wang R, Guo W, Ossipov M, Vanderah T, Porreca F, Lai J. Erratum to “glial cell line-derived neurotrophic factor normalizes neurochemical changes in injured dorsal root ganglion neurons and prevents the expression of experimental neuropathic pain” Neuroscience. 126: 247. DOI: 10.1016/J.Neuroscience.2004.03.032 |
0.7 |
|
2004 |
Gavva N, Klionsky L, Qu Y, Shi L, Tamir R, Edenson S, Zhang T, Viswanadhan V, Toth A, Vanderah T, Porreca F, Blumberg P, Lile J, Sun Y, Wild K, et al. Receptors and channels The Journal of Pain. 5: S6. DOI: 10.1016/j.jpain.2004.02.561 |
0.386 |
|
2003 |
Wang R, Guo W, Ossipov MH, Vanderah TW, Porreca F, Lai J. Glial cell line-derived neurotrophic factor normalizes neurochemical changes in injured dorsal root ganglion neurons and prevents the expression of experimental neuropathic pain. Neuroscience. 121: 815-24. PMID 14568039 DOI: 10.1016/S0306-4522(03)00491-3 |
0.762 |
|
2003 |
Gardell LR, Wang R, Ehrenfels C, Ossipov MH, Rossomando AJ, Miller S, Buckley C, Cai AK, Tse A, Foley SF, Gong B, Walus L, Carmillo P, Worley D, Huang C, ... ... Vanderah TW, et al. Multiple actions of systemic artemin in experimental neuropathy. Nature Medicine. 9: 1383-9. PMID 14528299 DOI: 10.1038/Nm944 |
0.82 |
|
2003 |
Quartilho A, Mata HP, Ibrahim MM, Vanderah TW, Porreca F, Makriyannis A, Malan TP. Inhibition of inflammatory hyperalgesia by activation of peripheral CB2 cannabinoid receptors. Anesthesiology. 99: 955-60. PMID 14508331 DOI: 10.1097/00000542-200310000-00031 |
0.568 |
|
2003 |
Gardell LR, Vanderah TW, Gardell SE, Wang R, Ossipov MH, Lai J, Porreca F. Enhanced evoked excitatory transmitter release in experimental neuropathy requires descending facilitation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 8370-9. PMID 12967999 DOI: 10.1523/Jneurosci.23-23-08370.2003 |
0.811 |
|
2003 |
Ibrahim MM, Deng H, Zvonok A, Cockayne DA, Kwan J, Mata HP, Vanderah TW, Lai J, Porreca F, Makriyannis A, Malan TP. Activation of CB2 cannabinoid receptors by AM1241 inhibits experimental neuropathic pain: pain inhibition by receptors not present in the CNS. Proceedings of the National Academy of Sciences of the United States of America. 100: 10529-33. PMID 12917492 DOI: 10.1073/Pnas.1834309100 |
0.733 |
|
2003 |
Wessells H, Hruby VJ, Hackett J, Han G, Balse-Srinivasan P, Vanderah TW. MT-II induces penile erection via brain and spinal mechanisms. Annals of the New York Academy of Sciences. 994: 90-5. PMID 12851302 DOI: 10.1111/J.1749-6632.2003.Tb03166.X |
0.322 |
|
2003 |
Ossipov MH, Lai J, Vanderah TW, Porreca F. Induction of pain facilitation by sustained opioid exposure: relationship to opioid antinociceptive tolerance. Life Sciences. 73: 783-800. PMID 12801599 DOI: 10.1016/S0024-3205(03)00410-7 |
0.757 |
|
2003 |
Hruby VJ, Agnes RS, Davis P, Ma SW, Lee YS, Vanderah TW, Lai J, Porreca F. Design of novel peptide ligands which have opioid agonist activity and CCK antagonist activity for the treatment of pain. Life Sciences. 73: 699-704. PMID 12801591 DOI: 10.1016/S0024-3205(03)00390-4 |
0.718 |
|
2003 |
Wessells H, Hruby VJ, Hackett J, Han G, Balse-Srinivasan P, Vanderah TW. Ac-Nle-c[Asp-His-DPhe-Arg-Trp-Lys]-NH2 induces penile erection via brain and spinal melanocortin receptors. Neuroscience. 118: 755-62. PMID 12710982 DOI: 10.1016/S0306-4522(02)00866-7 |
0.324 |
|
2003 |
Malan TP, Ibrahim MM, Lai J, Vanderah TW, Makriyannis A, Porreca F. CB2 cannabinoid receptor agonists: pain relief without psychoactive effects? Current Opinion in Pharmacology. 3: 62-7. PMID 12550743 DOI: 10.1016/S1471-4892(02)00004-8 |
0.738 |
|
2003 |
Hosohata K, Varga EV, Alfaro-Lopez J, Tang X, Vanderah TW, Porreca F, Hruby VJ, Roeske WR, Yamamura HI. (2S,3R) beta-methyl-2',6'-dimethyltyrosine-L-tetrahydroisoquinoline-3-carboxylic acid [(2S,3R)TMT-L-Tic-OH] is a potent, selective delta-opioid receptor antagonist in mouse brain. The Journal of Pharmacology and Experimental Therapeutics. 304: 683-8. PMID 12538822 DOI: 10.1124/Jpet.102.042929 |
0.599 |
|
2002 |
Malan TP, Ibrahim MM, Vanderah TW, Makriyannis A, Porreca F. Inhibition of pain responses by activation of CB(2) cannabinoid receptors. Chemistry and Physics of Lipids. 121: 191-200. PMID 12505700 DOI: 10.1016/S0009-3084(02)00155-X |
0.616 |
|
2002 |
Gardell LR, Ossipov MH, Vanderah TW, Lai J, Porreca F. Dynorphin-independent spinal cannabinoid antinociception. Pain. 100: 243-8. PMID 12467995 DOI: 10.1016/S0304-3959(02)00173-2 |
0.831 |
|
2002 |
Gardell LR, Wang R, Burgess SE, Ossipov MH, Vanderah TW, Malan TP, Lai J, Porreca F. Sustained morphine exposure induces a spinal dynorphin-dependent enhancement of excitatory transmitter release from primary afferent fibers. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 6747-55. PMID 12151554 DOI: 10.1523/Jneurosci.22-15-06747.2002 |
0.836 |
|
2002 |
Burgess SE, Gardell LR, Ossipov MH, Malan TP, Vanderah TW, Lai J, Porreca F. Time-dependent descending facilitation from the rostral ventromedial medulla maintains, but does not initiate, neuropathic pain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 5129-36. PMID 12077208 DOI: 10.1523/Jneurosci.22-12-05129.2002 |
0.832 |
|
2001 |
Lai J, Ossipov MH, Vanderah TW, Malan TP, Porreca F. Neuropathic pain: the paradox of dynorphin. Molecular Interventions. 1: 160-7. PMID 14993349 |
0.387 |
|
2001 |
Rasband MN, Park EW, Vanderah TW, Lai J, Porreca F, Trimmer JS. Distinct potassium channels on pain-sensing neurons. Proceedings of the National Academy of Sciences of the United States of America. 98: 13373-8. PMID 11698689 DOI: 10.1073/Pnas.231376298 |
0.64 |
|
2001 |
Malan TP, Ibrahim MM, Deng H, Liu Q, Mata HP, Vanderah T, Porreca F, Makriyannis A. CB2 cannabinoid receptor-mediated peripheral antinociception. Pain. 93: 239-45. PMID 11514083 DOI: 10.1016/S0304-3959(01)00321-9 |
0.593 |
|
2001 |
Porreca F, Burgess SE, Gardell LR, Vanderah TW, Malan TP, Ossipov MH, Lappi DA, Lai J. Inhibition of neuropathic pain by selective ablation of brainstem medullary cells expressing the mu-opioid receptor. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 5281-8. PMID 11438603 DOI: 10.1523/Jneurosci.21-14-05281.2001 |
0.859 |
|
2001 |
Simoneau II, Hamza MS, Mata HP, Siegel EM, Vanderah TW, Porreca F, Makriyannis A, Malan TP. The cannabinoid agonist WIN55,212-2 suppresses opioid-induced emesis in ferrets. Anesthesiology. 94: 882-7. PMID 11388542 DOI: 10.1097/00000542-200105000-00029 |
0.598 |
|
2001 |
Vanderah TW, Ossipov MH, Lai J, Malan TP, Porreca F. Mechanisms of opioid-induced pain and antinociceptive tolerance: descending facilitation and spinal dynorphin. Pain. 92: 5-9. PMID 11323121 DOI: 10.1016/S0304-3959(01)00311-6 |
0.746 |
|
2001 |
Wang Z, Gardell LR, Ossipov MH, Vanderah TW, Brennan MB, Hochgeschwender U, Hruby VJ, Malan TP, Lai J, Porreca F. Pronociceptive actions of dynorphin maintain chronic neuropathic pain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 1779-86. PMID 11222667 DOI: 10.1523/Jneurosci.21-05-01779.2001 |
0.828 |
|
2001 |
Vanderah TW, Suenaga NM, Ossipov MH, Malan TP, Lai J, Porreca F. Tonic descending facilitation from the rostral ventromedial medulla mediates opioid-induced abnormal pain and antinociceptive tolerance. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 279-86. PMID 11150345 DOI: 10.1523/Jneurosci.21-01-00279.2001 |
0.645 |
|
2000 |
Vanderah TW, Gardell LR, Burgess SE, Ibrahim M, Dogrul A, Zhong CM, Zhang ET, Malan TP, Ossipov MH, Lai J, Porreca F. Dynorphin promotes abnormal pain and spinal opioid antinociceptive tolerance. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 7074-9. PMID 10995854 DOI: 10.1523/Jneurosci.20-18-07074.2000 |
0.842 |
|
2000 |
Hosohata K, Logan JK, Varga E, Burkey TH, Vanderah TW, Porreca F, Hruby VJ, Roeske WR, Yamamura HI. The role of the G protein gamma(2) subunit in opioid antinociception in mice. European Journal of Pharmacology. 392: R9-R11. PMID 10762674 DOI: 10.1016/S0014-2999(00)00132-1 |
0.586 |
|
2000 |
Hosohata Y, Vanderah TW, Burkey TH, Ossipov MH, Kovelowski CJ, Sora I, Uhl GR, Zhang X, Rice KC, Roeske WR, Hruby VJ, Yamamura HI, Lai J, Porreca F. delta-Opioid receptor agonists produce antinociception and [35S]GTPgammaS binding in mu receptor knockout mice. European Journal of Pharmacology. 388: 241-8. PMID 10675732 DOI: 10.1016/S0014-2999(99)00897-3 |
0.742 |
|
1998 |
Vanderah TW, Raffa RB, Lashbrook J, Burritt A, Hruby V, Porreca F. Orphanin-FQ/nociceptin: lack of anti nociceptive, hyperalgesic or allodynic effects in acute thermal or mechanical tests following intracerebroventricular or intrathecal administration to mice or rats. European Journal of Pain (London, England). 2: 267-78. PMID 15102387 DOI: 10.1016/S1090-3801(98)90023-4 |
0.555 |
|
1998 |
Vanderah TW, Raffa RB, Lashbrook J, Burritt A, Hruby V, Porreca F. Orphanin-fq/nociceptin: Lack of antinociceptive, hyperalgesic or allodynic effects in acute thermal or mechanical tests following intracerebroventricular or intrathecal administration to mice or rats European Journal of Pain. 2: 267-280. DOI: 10.1016/S1090-3801(98)90023-4 |
0.419 |
|
1998 |
Castex N, Levine B, Vanderah T, Junien J, Porreca F, Riviere P. Spinal and peripheral kappa and mu opioid receptor agonists inhibit the response to noxious colorectal distension (CRD) Gastroenterology. 114: A1134. DOI: 10.1016/S0016-5085(98)84609-X |
0.529 |
|
1997 |
Laughlin TM, Vanderah TW, Lashbrook J, Nichols ML, Ossipov M, Porreca F, Wilcox GL. Spinally administered dynorphin A produces long-lasting allodynia: involvement of NMDA but not opioid receptors. Pain. 72: 253-60. PMID 9272810 DOI: 10.1016/S0304-3959(97)00046-8 |
0.625 |
|
1997 |
Wegert S, Ossipov MH, Nichols ML, Bian D, Vanderah TW, Malan TP, Porreca F. Differential activities of intrathecal MK-801 or morphine to alter responses to thermal and mechanical stimuli in normal or nerve-injured rats. Pain. 71: 57-64. PMID 9200174 DOI: 10.1016/S0304-3959(97)03337-X |
0.662 |
|
1996 |
Vanderah TW, Laughlin T, Lashbrook JM, Nichols ML, Wilcox GL, Ossipov MH, Malan TP, Porreca F. Single intrathecal injections of dynorphin A or des-Tyr-dynorphins produce long-lasting allodynia in rats: blockade by MK-801 but not naloxone. Pain. 68: 275-81. PMID 9121815 DOI: 10.1016/S0304-3959(96)03225-3 |
0.584 |
|
1996 |
Vanderah TW, Bernstein RN, Yamamura HI, Hruby VJ, Porreca F. Enhancement of morphine antinociception by a CCKB antagonist in mice is mediated via opioid delta receptors. The Journal of Pharmacology and Experimental Therapeutics. 278: 212-9. PMID 8764354 |
0.518 |
|
1996 |
Edsall SA, Knapp RJ, Vanderah TW, Roeske WR, Consroe P, Yamamura HI. Antisense oligodeoxynucleotide treatment to the brain cannabinoid receptor inhibits antinociception. Neuroreport. 7: 593-6. PMID 8730837 DOI: 10.1097/00001756-199601310-00052 |
0.561 |
|
1996 |
Zaki PA, Bilsky EJ, Vanderah TW, Lai J, Evans CJ, Porreca F. Opioid receptor types and subtypes: the delta receptor as a model. Annual Review of Pharmacology and Toxicology. 36: 379-401. PMID 8725395 DOI: 10.1146/Annurev.Pa.36.040196.002115 |
0.708 |
|
1995 |
Vanderah TW, Bernstein RN, Lai J, Porreca F. PRODUCTION OF NALTRINDOLE-SENSITIVE ANTINOCICEPTION BY A CHOLECYSTOKININ (CCK) ANTAGONIST AND THIORPHAN: EVIDENCE FOR TONIC INHIBITION OF ENKEPHALIN RELEASE BY CCK Analgesia. 1: 813-816. DOI: 10.3727/107156995819563546 |
0.614 |
|
1994 |
Vanderah T, Takemori AE, Sultana M, Portoghese PS, Mosberg HI, Hruby VJ, Haaseth RC, Matsunaga TO, Porreca F. Interaction of [D-Pen2,D-Pen5]enkephalin and [D-Ala2,Glu4]deltorphin with delta-opioid receptor subtypes in vivo. European Journal of Pharmacology. 252: 133-7. PMID 8157053 DOI: 10.1016/0014-2999(94)90588-6 |
0.574 |
|
1994 |
Sora I, Richman J, Santoro G, Wei HB, Wang Y, Vanderah T, Horvath R, Nguyen M, Waite S, Roeske WR, Yamamura HI. The Cloning and Expression of a Human Creatine Transporter Biochemical and Biophysical Research Communications. 204: 419-427. PMID 7945388 DOI: 10.1006/bbrc.1994.2475 |
0.436 |
|
1994 |
Ossipov MH, Kovelowski CJ, Vanderah T, Porreca F. Naltrindole, an opioid δ antagonist, blocks the enhancement of morphine-antinociception induced by a CCKB antagonist in the rat Neuroscience Letters. 181: 9-12. PMID 7898778 DOI: 10.1016/0304-3940(94)90548-7 |
0.596 |
|
1994 |
Vanderah TW, Lai J, Yamamura HI, Porreca F. Antisense oligodeoxynucleotide to the CCKB receptor produces naltrindole- and [Leu5]enkephalin antiserum-sensitive enhancement of morphine antinociception. Neuroreport. 5: 2601-5. PMID 7696612 DOI: 10.1097/00001756-199412000-00049 |
0.763 |
|
1993 |
Mattia A, Vanderah T, Raffa RB, Vaught JL, Tallarida RJ, Porreca F. Characterization of the unusual antinociceptive profile of tramadol in mice Drug Development Research. 28: 176-182. DOI: 10.1002/ddr.430280208 |
0.554 |
|
1992 |
Vanderah TW, Wild KD, Takemori AE, Sultana M, Portoghese PS, Bowen WD, Mosberg HI, Porreca F. Mediation of swim-stress antinociception by the opioid delta 2 receptor in the mouse. The Journal of Pharmacology and Experimental Therapeutics. 262: 190-7. PMID 1320682 |
0.305 |
|
1991 |
Mattia A, Vanderah T, Mosberg HI, Omnaas JR, Bowen WD, Porreca F. Pharmacological characterization of [D-Ala2,Leu5,Ser6]enkephalin (DALES): antinociceptive actions at the δnon-complexed-opioid receptor European Journal of Pharmacology. 192: 371-375. PMID 1647317 DOI: 10.1016/0014-2999(91)90227-H |
0.582 |
|
1991 |
Wild KD, Vanderah T, Mosberg HI, Porreca F. Opioid δ receptor subtypes are associated with different potassium channels European Journal of Pharmacology. 193: 135-136. PMID 1646729 DOI: 10.1016/0014-2999(91)90215-C |
0.464 |
|
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