James J. Champoux - Publications

Affiliations: 
University of Washington, Seattle, Seattle, WA 
Area:
Microbiology Biology, Molecular Biology

104 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2011 Interthal H, Champoux JJ. Effects of DNA and protein size on substrate cleavage by human tyrosyl-DNA phosphodiesterase 1. The Biochemical Journal. 436: 559-66. PMID 21463258 DOI: 10.1042/Bj20101841  0.572
2010 Schultz SJ, Zhang M, Champoux JJ. Multiple nucleotide preferences determine cleavage-site recognition by the HIV-1 and M-MuLV RNases H. Journal of Molecular Biology. 397: 161-78. PMID 20122939 DOI: 10.1016/J.Jmb.2010.01.059  0.455
2009 Schultz SJ, Zhang M, Champoux JJ. Preferred sequences within a defined cleavage window specify DNA 3' end-directed cleavages by retroviral RNases H. The Journal of Biological Chemistry. 284: 32225-38. PMID 19778906 DOI: 10.1074/Jbc.M109.043158  0.6
2009 Yang Z, Champoux JJ. Assays for the preferential binding of human topoisomerase I to supercoiled DNA. Methods in Molecular Biology (Clifton, N.J.). 582: 49-57. PMID 19763941 DOI: 10.1007/978-1-60761-340-4_5  0.578
2009 Yang Z, Carey JF, Champoux JJ. Mutational analysis of the preferential binding of human topoisomerase I to supercoiled DNA. The Febs Journal. 276: 5906-19. PMID 19740104 DOI: 10.1111/J.1742-4658.2009.07270.X  0.587
2009 Champoux JJ, Schultz SJ. Ribonuclease H: properties, substrate specificity and roles in retroviral reverse transcription. The Febs Journal. 276: 1506-16. PMID 19228195 DOI: 10.1111/J.1742-4658.2009.06909.X  0.63
2008 Kim H, Cardellina JH, Akee R, Champoux JJ, Stivers JT. Arylstibonic acids: novel inhibitors and activators of human topoisomerase IB. Bioorganic Chemistry. 36: 190-7. PMID 18508107 DOI: 10.1016/J.Bioorg.2008.04.001  0.529
2008 Schultz SJ, Champoux JJ. RNase H activity: structure, specificity, and function in reverse transcription. Virus Research. 134: 86-103. PMID 18261820 DOI: 10.1016/J.Virusres.2007.12.007  0.49
2007 Hirano R, Interthal H, Huang C, Nakamura T, Deguchi K, Choi K, Bhattacharjee MB, Arimura K, Umehara F, Izumo S, Northrop JL, Salih MA, Inoue K, Armstrong DL, Champoux JJ, et al. Spinocerebellar ataxia with axonal neuropathy: consequence of a Tdp1 recessive neomorphic mutation? The Embo Journal. 26: 4732-43. PMID 17948061 DOI: 10.1038/Sj.Emboj.7601885  0.456
2007 Paulson BA, Zhang M, Schultz SJ, Champoux JJ. Substitution of alanine for tyrosine-64 in the fingers subdomain of M-MuLV reverse transcriptase impairs strand displacement synthesis and blocks viral replication in vivo. Virology. 366: 361-76. PMID 17532359 DOI: 10.1016/J.Virol.2007.04.028  0.577
2006 Davies DR, Mushtaq A, Interthal H, Champoux JJ, Hol WG. The structure of the transition state of the heterodimeric topoisomerase I of Leishmania donovani as a vanadate complex with nicked DNA. Journal of Molecular Biology. 357: 1202-10. PMID 16487540 DOI: 10.1016/J.Jmb.2006.01.022  0.592
2006 Lanciault C, Champoux JJ. Pausing during reverse transcription increases the rate of retroviral recombination. Journal of Virology. 80: 2483-94. PMID 16474155 DOI: 10.1128/Jvi.80.5.2483-2494.2006  0.764
2006 Schultz SJ, Zhang M, Champoux JJ. Sequence, distance, and accessibility are determinants of 5'-end-directed cleavages by retroviral RNases H. The Journal of Biological Chemistry. 281: 1943-55. PMID 16306040 DOI: 10.1074/Jbc.M510504200  0.488
2005 Interthal H, Chen HJ, Champoux JJ. Human Tdp1 cleaves a broad spectrum of substrates, including phosphoamide linkages. The Journal of Biological Chemistry. 280: 36518-28. PMID 16141202 DOI: 10.1074/Jbc.M508898200  0.618
2005 Interthal H, Chen HJ, Kehl-Fie TE, Zotzmann J, Leppard JB, Champoux JJ. SCAN1 mutant Tdp1 accumulates the enzyme--DNA intermediate and causes camptothecin hypersensitivity. The Embo Journal. 24: 2224-33. PMID 15920477 DOI: 10.1038/Sj.Emboj.7600694  0.553
2005 Leppard JB, Champoux JJ. Human DNA topoisomerase I: relaxation, roles, and damage control. Chromosoma. 114: 75-85. PMID 15830206 DOI: 10.1007/S00412-005-0345-5  0.602
2005 Lanciault C, Champoux JJ. Effects of unpaired nucleotides within HIV-1 genomic secondary structures on pausing and strand transfer. The Journal of Biological Chemistry. 280: 2413-23. PMID 15542863 DOI: 10.1074/Jbc.M410718200  0.737
2004 Schultz SJ, Zhang M, Champoux JJ. Recognition of internal cleavage sites by retroviral RNases H. Journal of Molecular Biology. 344: 635-52. PMID 15533434 DOI: 10.1016/J.Jmb.2004.09.081  0.526
2004 Winshell J, Paulson BA, Buelow BD, Champoux JJ. Requirements for DNA unpairing during displacement synthesis by HIV-1 reverse transcriptase. The Journal of Biological Chemistry. 279: 52924-33. PMID 15465813 DOI: 10.1074/Jbc.M409134200  0.619
2004 Lanciault C, Champoux JJ. Single unpaired nucleotides facilitate HIV-1 reverse transcriptase displacement synthesis through duplex RNA. The Journal of Biological Chemistry. 279: 32252-61. PMID 15169769 DOI: 10.1074/Jbc.M404117200  0.729
2004 Davies DR, Interthal H, Champoux JJ, Hol WG. Explorations of peptide and oligonucleotide binding sites of tyrosyl-DNA phosphodiesterase using vanadate complexes. Journal of Medicinal Chemistry. 47: 829-37. PMID 14761185 DOI: 10.1021/Jm030487X  0.488
2004 Interthal H, Quigley PM, Hol WG, Champoux JJ. The role of lysine 532 in the catalytic mechanism of human topoisomerase I. The Journal of Biological Chemistry. 279: 2984-92. PMID 14594810 DOI: 10.1074/Jbc.M309959200  0.454
2003 Roy R, Trowbridge P, Yang Z, Champoux JJ, Simmons DT. The cap region of topoisomerase I binds to sites near both ends of simian virus 40 T antigen. Journal of Virology. 77: 9809-16. PMID 12941889 DOI: 10.1128/Jvi.77.18.9809-9816.2003  0.41
2003 Carey JF, Schultz SJ, Sisson L, Fazzio TG, Champoux JJ. DNA relaxation by human topoisomerase I occurs in the closed clamp conformation of the protein. Proceedings of the National Academy of Sciences of the United States of America. 100: 5640-5. PMID 12711735 DOI: 10.1073/Pnas.1031537100  0.61
2003 Schultz SJ, Zhang M, Champoux JJ. Specific cleavages by RNase H facilitate initiation of plus-strand RNA synthesis by Moloney murine leukemia virus. Journal of Virology. 77: 5275-85. PMID 12692229 DOI: 10.1128/Jvi.77.9.5275-5285.2003  0.62
2003 Davies DR, Interthal H, Champoux JJ, Hol WG. Crystal structure of a transition state mimic for Tdp1 assembled from vanadate, DNA, and a topoisomerase I-derived peptide. Chemistry & Biology. 10: 139-47. PMID 12618186 DOI: 10.1016/S1074-5521(03)00021-8  0.57
2002 Davies DR, Interthal H, Champoux JJ, Hol WG. Insights into substrate binding and catalytic mechanism of human tyrosyl-DNA phosphodiesterase (Tdp1) from vanadate and tungstate-inhibited structures. Journal of Molecular Biology. 324: 917-32. PMID 12470949 DOI: 10.1016/S0022-2836(02)01154-3  0.589
2002 Champoux JJ. Type IA DNA topoisomerases: strictly one step at a time. Proceedings of the National Academy of Sciences of the United States of America. 99: 11998-2000. PMID 12221296 DOI: 10.1073/Pnas.202483499  0.608
2002 Yang Z, Champoux JJ. Reconstitution of enzymatic activity by the association of the cap and catalytic domains of human topoisomerase I. The Journal of Biological Chemistry. 277: 30815-23. PMID 12077150 DOI: 10.1074/Jbc.M205302200  0.587
2002 Champoux JJ. A first view of the structure of a type IA topoisomerase with bound DNA. Trends in Pharmacological Sciences. 23: 199-201. PMID 12007989 DOI: 10.1016/S0165-6147(02)01997-1  0.554
2002 Davies DR, Interthal H, Champoux JJ, Hol WG. The crystal structure of human tyrosyl-DNA phosphodiesterase, Tdp1. Structure (London, England : 1993). 10: 237-48. PMID 11839309 DOI: 10.1016/S0969-2126(02)00707-4  0.589
2001 Interthal H, Pouliot JJ, Champoux JJ. The tyrosyl-DNA phosphodiesterase Tdp1 is a member of the phospholipase D superfamily Proceedings of the National Academy of Sciences of the United States of America. 98: 12009-12014. PMID 11572945 DOI: 10.1073/Pnas.211429198  0.514
2001 Champoux JJ. DNA topoisomerases: Structure, function, and mechanism Annual Review of Biochemistry. 70: 369-413. PMID 11395412 DOI: 10.1146/Annurev.Biochem.70.1.369  0.609
2001 Winshell J, Champoux JJ. Structural alterations in the DNA ahead of the primer terminus during displacement synthesis by reverse transcriptases Journal of Molecular Biology. 306: 931-943. PMID 11237609 DOI: 10.1006/Jmbi.2001.4439  0.664
2001 Champoux JJ. DNA topoisomerase I-mediated nicking of circular duplex DNA Methods in Molecular Biology (Clifton, N.J.). 95: 81-87. PMID 11089222 DOI: 10.1385/1-59259-057-8:81  0.573
2001 Stewart L, Champoux JJ. Assaying DNA topoisomerase I relaxation activity Methods in Molecular Biology (Clifton, N.J.). 95: 1-11. PMID 11089214 DOI: 10.1385/1-59259-057-8:1  0.532
2001 Yang Z, Champoux JJ. The role of histidine 632 in catalysis by human topoisomerase I Journal of Biological Chemistry. 276: 677-685. PMID 11024057 DOI: 10.1074/Jbc.M007593200  0.339
2000 Champoux JJ. Structure-based analysis of the effects of camptothecin on the activities of human topoisomerase I Annals of the New York Academy of Sciences. 922: 56-64. PMID 11193925 DOI: 10.1111/J.1749-6632.2000.Tb07025.X  0.544
2000 Schultz SJ, Zhang M, Kelleher CD, Champoux JJ. Analysis of plus-strand primer selection, removal, and reutilization by retroviral reverse transcriptases Journal of Biological Chemistry. 275: 32299-32309. PMID 10913435 DOI: 10.1074/Jbc.M000021200  0.637
2000 Redinbo MR, Champoux JJ, Hol WG. Novel insights into catalytic mechanism from a crystal structure of human topoisomerase I in complex with DNA. Biochemistry. 39: 6832-40. PMID 10841763 DOI: 10.1021/Bi992690T  0.607
2000 Ireton GC, Stewart L, Parker LH, Champoux JJ. Expression of human topoisomerase I with a partial deletion of the linker region yields monomeric and dimeric enzymes that respond differently to camptothecin Journal of Biological Chemistry. 275: 25820-25830. PMID 10827183 DOI: 10.1074/Jbc.M002144200  0.395
2000 Kelleher CD, Champoux JJ. RNA degradation and primer selection by Moloney murine leukemia virus reverse transcriptase contribute to the accuracy of plus strand initiation Journal of Biological Chemistry. 275: 13061-13070. PMID 10777611 DOI: 10.1074/Jbc.275.17.13061  0.536
1999 Stewart L, Champoux JJ. Purification of baculovirus-expressed human DNA topoisomerase I Methods in Molecular Biology (Clifton, N.J.). 94: 223-234. PMID 12844878 DOI: 10.1385/1-59259-259-7:223  0.487
1999 Schultz SJ, Zhang M, Kelleher CD, Champoux JJ. Polypurine tract primer generation and utilization by moloney murine leukemia virus reverse transcriptase Journal of Biological Chemistry. 274: 34547-34555. PMID 10574917 DOI: 10.1074/Jbc.274.49.34547  0.605
1999 Stewart L, Ireton GC, Champoux JJ. A functional linker in human topoisomerase I is required for maximum sensitivity to camptothecin in a DNA relaxation assay Journal of Biological Chemistry. 274: 32950-32960. PMID 10551862 DOI: 10.1074/Jbc.274.46.32950  0.492
1999 Redinbo MR, Stewart L, Champoux JJ, Hol WG. Structural flexibility in human topoisomerase I revealed in multiple non-isomorphous crystal structures. Journal of Molecular Biology. 292: 685-96. PMID 10497031 DOI: 10.1006/Jmbi.1999.3065  0.423
1999 Redinbo MR, Champoux JJ, Hol WG. Structural insights into the function of type IB topoisomerases. Current Opinion in Structural Biology. 9: 29-36. PMID 10047584 DOI: 10.1016/S0959-440X(99)80005-0  0.508
1999 Samejima K, Svingen PA, Basi GS, Kottke T, Mesner PW, Stewart L, Durrieu F, Poirier GG, Alnemri ES, Champoux JJ, Kaufmann SH, Earnshaw WC. Caspase-mediated cleavage of DNA topoisomerase I at unconventional sites during apoptosis. The Journal of Biological Chemistry. 274: 4335-40. PMID 9933635 DOI: 10.1074/Jbc.274.7.4335  0.377
1998 Whiting SH, Champoux JJ. Properties of strand displacement synthesis by Moloney murine leukemia virus reverse transcriptase: Mechanistic implications Journal of Molecular Biology. 278: 559-577. PMID 9600839 DOI: 10.1006/Jmbi.1998.1720  0.534
1998 Champoux JJ. Domains of human topoisomerase I and associated functions Progress in Nucleic Acid Research and Molecular Biology. 60: 111-132. PMID 9594573 DOI: 10.1016/S0079-6603(08)60891-0  0.408
1998 Kelleher CD, Champoux JJ. Characterization of RNA strand displacement synthesis by moloney murine leukemia virus reverse transcriptase Journal of Biological Chemistry. 273: 9976-9986. PMID 9545343 DOI: 10.1074/Jbc.273.16.9976  0.55
1998 Stewart L, Redinbo MR, Qiu X, Hol WG, Champoux JJ. A model for the mechanism of human topoisomerase I. Science (New York, N.Y.). 279: 1534-41. PMID 9488652 DOI: 10.1126/Science.279.5356.1534  0.563
1998 Redinbo MR, Stewart L, Kuhn P, Champoux JJ, Hol WG. Crystal structures of human topoisomerase I in covalent and noncovalent complexes with DNA. Science (New York, N.Y.). 279: 1504-13. PMID 9488644 DOI: 10.1126/Science.279.5356.1504  0.598
1997 Stewart L, Ireton GC, Champoux JJ. Reconstitution of human topoisomerase I by fragment complementation Journal of Molecular Biology. 269: 355-372. PMID 9199405 DOI: 10.1006/Jmbi.1997.1056  0.438
1996 Schultz SJ, Champoux JJ. RNase H domain of Moloney murine leukemia virus reverse transcriptase retains activity but requires the polymerase domain for specificity Journal of Virology. 70: 8630-8638. PMID 8970988  0.42
1996 Stewart L, Ireton GC, Champoux JJ. The domain organization of human topoisomerase I Journal of Biological Chemistry. 271: 7602-7608. PMID 8631794 DOI: 10.1074/Jbc.271.13.7602  0.469
1996 Stewart L, Ireton GC, Parker LH, Madden KR, Champoux JJ. Biochemical and biophysical analyses of recombinant forms of human topoisomerase I Journal of Biological Chemistry. 271: 7593-7601. PMID 8631793 DOI: 10.1074/Jbc.271.13.7593  0.354
1995 Schultz SJ, Whiting SH, Champoux JJ. Cleavage specificities of Moloney murine leukemia virus RNase H implicated in the second strand transfer during reverse transcription Journal of Biological Chemistry. 270: 24135-24145. PMID 7592616 DOI: 10.1074/Jbc.270.41.24135  0.604
1995 Madden KR, Stewart L, Champoux JJ. Preferential binding of human topoisomerase I to superhelical DNA Embo Journal. 14: 5399-5409. PMID 7489729 DOI: 10.1002/J.1460-2075.1995.Tb00224.X  0.599
1994 Champoux JJ. Mechanism of catalysis by eukaryotic DNA topoisomerase I Advances in Pharmacology (San Diego, Calif.). 29: 71-82. PMID 7826865 DOI: 10.1016/S1054-3589(08)60540-2  0.475
1994 Whiting SH, Champoux JJ. Strand displacement synthesis capability of Moloney murine leukemia virus reverse transcriptase Journal of Virology. 68: 4747-4758. PMID 7518525 DOI: 10.1128/Jvi.68.8.4747-4758.1994  0.613
1994 Randolph CA, Champoux JJ. The use of DNA and RNA oligonucleotides in hybrid structures with longer polynucleotide chains to probe the structural requirements for Moloney murine leukemia virus plus strand priming Journal of Biological Chemistry. 269: 19207-19215. PMID 7518453  0.603
1993 Randolph CA, Champoux JJ. The Majority of Simian Immunodeficiency Virus/Mne Circle Junctions Result from Ligation of Unintegrated Viral DNA Ends That Are Aberrant for Integration Virology. 194: 851-854. PMID 8503190 DOI: 10.1006/Viro.1993.1329  0.497
1993 Merino A, Madden KR, Lane WS, Champoux JJ, Reinberg D. DNA topoisomerase I is involved in both repression and activation of transcription Nature. 365: 227-232. PMID 8396729 DOI: 10.1038/365227A0  0.438
1993 Parker LH, Champoux JJ. Analysis of the biased distribution of topoisomerase I break sites on replicating simian virus 40 DNA. Journal of Molecular Biology. 231: 6-18. PMID 8388476 DOI: 10.1006/Jmbi.1993.1252  0.574
1993 Salazar M, Champoux JJ, Reid BR. Sugar conformations at hybrid duplex junctions in HIV-1 and Okazaki fragments. Biochemistry. 32: 739-44. PMID 8380708 DOI: 10.1021/Bi00054A002  0.611
1993 Pullen KA, Rattray AJ, Champoux JJ. The sequence features important for plus strand priming by human immunodeficiency virus type 1 reverse transcriptase. The Journal of Biological Chemistry. 268: 6221-7. PMID 7681062  0.359
1992 Pullen KA, Ishimoto LK, Champoux JJ. Incomplete removal of the RNA primer for minus-strand DNA synthesis by human immunodeficiency virus type 1 reverse transcriptase. Journal of Virology. 66: 367-73. PMID 1370087  0.548
1992 Champoux JJ. Topoisomerase I is preferentially associated with normal SV40 replicative intermediates, but is associated with both replicating and nonreplicating SV40 DNAs which are deficient in histones Nucleic Acids Research. 20: 3347-3352. PMID 1321412 DOI: 10.1093/Nar/20.13.3347  0.588
1990 Krogstad PA, Champoux JJ. Sequence-specific binding of DNA by the moloney murine leukemia virus integrase protein Journal of Virology. 64: 2796-2801. PMID 2186176  0.47
1989 Porter SE, Champoux JJ. The basis for camptothecin enhancement of DNA breakage by eukaryotic topoisomerase I. Nucleic Acids Research. 17: 8521-32. PMID 2555774 DOI: 10.1093/Nar/17.21.8521  0.507
1989 Porter SE, Champoux JJ. Mapping in vivo topoisomerase I sites on simian virus 40 DNA: asymmetric distribution of sites on replicating molecules. Molecular and Cellular Biology. 9: 541-50. PMID 2540421  0.437
1989 Champoux JJ, Aronoff R. The effects of camptothecin on the reaction and the specificity of the wheat germ type I topoisomerase Journal of Biological Chemistry. 264: 1010-1015. PMID 2536012  0.314
1989 Rattray AJ, Champoux JJ. Plus-strand priming by Moloney murine leukemia virus. The sequence features important for cleavage by RNase H Journal of Molecular Biology. 208: 445-456. PMID 2477553 DOI: 10.1016/0022-2836(89)90508-1  0.546
1988 Champoux JJ. Topoisomerase I is preferentially associated with isolated replicating simian virus 40 molecules after treatment of infected cells with camptothecin Journal of Virology. 62: 3675-3683. PMID 2843668 DOI: 10.1128/Jvi.62.10.3675-3683.1988  0.564
1987 Rattray AJ, Champoux JJ. The role of Moloney murine leukemia virus RNase H activity in the formation of plus-strand primers Journal of Virology. 61: 2843-2851. PMID 3039172 DOI: 10.1128/Jvi.61.9.2843-2851.1987  0.58
1986 McCoubrey WK, Champoux JJ. The role of single-strand breaks in the catenation reaction catalyzed by the rat type I topoisomerase Journal of Biological Chemistry. 261: 5130-5137. PMID 3007492  0.47
1985 Bullock P, Champoux JJ, Botchan M. Association of crossover points with topoisomerase I cleavage sites: A model for nonhomologous recombination Science. 230: 954-958. PMID 2997924 DOI: 10.1126/Science.2997924  0.513
1984 Been MD, Burgess RR, Champoux JJ. DNA strand breakage by wheat germ type 1 topoisomerase Bba - Gene Structure and Expression. 782: 304-312. PMID 6329302 DOI: 10.1016/0167-4781(84)90066-6  0.612
1984 Been MD, Burgess RR, Champoux JJ. Nucleotide sequence preference at rat liver and wheat germ type 1 DNA topoisomerase breakage sites in duplex SV40 DNA Nucleic Acids Research. 12: 3097-3114. PMID 6326051 DOI: 10.1093/Nar/12.7.3097  0.531
1984 Finston WI, Champoux JJ. RNA-primed initiation of moloney murine leukemia virus plus strands by reverse transcriptase in vitro Journal of Virology. 51: 26-33. PMID 6202882  0.487
1984 Champoux JJ, Gilboa E, Baltimore D. Mechanism of RNA primer removal by the RNase H activity of avian myeloblastosis virus reverse transcriptase Journal of Virology. 49: 686-691. PMID 6199510 DOI: 10.1128/Jvi.49.3.686-691.1984  0.598
1984 Champoux JJ, McCoubrey WK, Been MD. DNA structural features that lead to strand breakage by eukaryotic type-I topoisomerase Cold Spring Harbor Symposia On Quantitative Biology. 435-442. PMID 6099251 DOI: 10.1101/Sqb.1984.049.01.049  0.535
1984 Been MD, Champoux JJ. Breakage of single-stranded DNA by eukaryotic type 1 topoisomerase occurs only at regions with the potential for base-pairing Journal of Molecular Biology. 180: 515-531. PMID 6098684 DOI: 10.1016/0022-2836(84)90025-1  0.618
1983 Been MD, Champoux JJ. Cutting of M13mp7 phage DNA and excision of cloned single-stranded sequences by restriction endonucleases Methods in Enzymology. 90-98. PMID 6310344 DOI: 10.1016/0076-6879(83)01007-1  0.512
1983 Brewer BJ, Martin SR, Champoux JJ. A cellular single-stranded DNA-dependent ATPase associated with simian virus 40 chromatin Journal of Biological Chemistry. 258: 4496-4502. PMID 6131894  0.542
1981 McConaughy BL, Young LS, Champoux JJ. The effect of salt on the binding of the eucaryotic DNA nicking-closing enzyme to DNA and chromatin Bba Section Nucleic Acids and Protein Synthesis. 655: 1-8. PMID 6266479 DOI: 10.1016/0005-2787(81)90059-9  0.541
1981 Been MD, Champoux JJ. DNA breakage and closure by rat liver type 1 topoisomerase: separation of the half-reactions by using a single-stranded DNA substrate Proceedings of the National Academy of Sciences of the United States of America. 78: 2883-2887. PMID 6265921 DOI: 10.1073/Pnas.78.5.2883  0.57
1981 Champoux JJ. DNA is linked to the rat liver DNA nicking-closing enzyme by a phosphodiester bond to tyrosine Journal of Biological Chemistry. 256: 4805-4809. PMID 6262303  0.463
1980 Been MD, Champoux JJ. Breakage of single-stranded DNA by rat liver nicking-closing enzyme with the formation of a DNA-enzyme complex Nucleic Acids Research. 8: 6129-6142. PMID 6258163 DOI: 10.1093/Nar/8.24.6129  0.594
1979 Champoux JJ, Young LS, Been MD. Studies on the regulation and specificity of the DNA-untwisting enzyme Cold Spring Harbor Symposia On Quantitative Biology. 43: 53-58. PMID 225116 DOI: 10.1101/Sqb.1979.043.01.009  0.543
1978 Champoux JJ. Proteins that affect DNA conformation Annual Review of Biochemistry. 47: 449-479. PMID 209728 DOI: 10.1146/Annurev.Bi.47.070178.002313  0.591
1978 Young LS, Champoux JJ. Interaction of the DNA untwisting enzyme with the SV40 nucleoprotein complex Nucleic Acids Research. 5: 623-635. PMID 204912 DOI: 10.1093/Nar/5.2.623  0.571
1978 Champoux JJ. Mechanism of the reaction catalyzed by the DNA untwisting enzyme: Attachment of the enzyme to 3′-terminus of the nicked DNA Journal of Molecular Biology. 118: 441-446. PMID 204790 DOI: 10.1016/0022-2836(78)90238-3  0.584
1978 Durnford JM, Champoux JJ. The DNA untwisting enzyme from Saccharomyces cerevisiae. Partial purification and characterization Journal of Biological Chemistry. 253: 1086-1089. PMID 203580  0.478
1977 Heffron F, Bedinger P, Champoux JJ, Falkow S. Deletions affecting the transposition of an antibiotic resistance gene Proceedings of the National Academy of Sciences of the United States of America. 74: 702-706. PMID 322140 DOI: 10.1073/Pnas.74.2.702  0.367
1977 Champoux JJ. Renaturation of complementary single-stranded DNA circles: complete rewinding facilitated by the DNA untwisting enzyme Proceedings of the National Academy of Sciences of the United States of America. 74: 5328-5332. PMID 202951  0.545
1977 Champoux JJ. Strand breakage by the DNA untwisting enzyme results in covalent attachment of the enzyme to DNA Proceedings of the National Academy of Sciences of the United States of America. 74: 3800-3804. PMID 198805 DOI: 10.1073/Pnas.74.9.3800  0.569
1976 Champoux JJ. Evidence for an intermediate with a single strand break in the reaction catalyzed by the DNA untwisting enzyme Proceedings of the National Academy of Sciences of the United States of America. 73: 3488-3491. PMID 1068461 DOI: 10.1073/Pnas.73.10.3488  0.576
1976 Champoux JJ, McConaughy BL. Purification and characterization of the DNA untwisting enzyme from rat liver Biochemistry. 15: 4638-4642. PMID 184821 DOI: 10.1021/Bi00666A014  0.485
1975 Champoux JJ, McConaughy BL. Priming of superhelical SV40 DNA by Escherichia coli RNA polymerase for in vitro DNA synthesis Biochemistry. 14: 307-316. PMID 164202 DOI: 10.1021/Bi00673A017  0.617
1974 Roman A, Champoux JJ, Dulbecco R. Characterization of the replicative intermediates of polyoma virus. Virology. 57: 147-60. PMID 4131952 DOI: 10.1016/0042-6822(74)90116-0  0.503
1972 Champoux JJ, Hogness DS. The topography of lambda DNA: polyriboguanylic acid binding sites and base composition. Journal of Molecular Biology. 71: 383-405. PMID 4635990 DOI: 10.1016/0022-2836(72)90358-0  0.397
1972 Champoux JJ, Dulbecco R. An activity from mammalian cells that untwists superhelical DNA--a possible swivel for DNA replication (polyoma-ethidium bromide-mouse-embryo cells-dye binding assay). Proceedings of the National Academy of Sciences of the United States of America. 69: 143-6. PMID 4333036 DOI: 10.1073/Pnas.69.1.143  0.622
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