Joshua M. Stuart, Ph.D. - Publications

Affiliations: 
2004 Stanford University, Palo Alto, CA 
Area:
Biostatistics Biology, Molecular Biology, Biomedical Engineering

116 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Sundaram L, Kumar A, Zatzman M, Salcedo A, Ravindra N, Shams S, Louie BH, Bagdatli ST, Myers MA, Sarmashghi S, Choi HY, Choi WY, Yost KE, Zhao Y, Granja JM, ... ... Stuart JM, et al. Single-cell chromatin accessibility reveals malignant regulatory programs in primary human cancers. Science (New York, N.Y.). 385: eadk9217. PMID 39236169 DOI: 10.1126/science.adk9217  0.376
2021 Uzunangelov V, Wong CK, Stuart JM. Accurate cancer phenotype prediction with AKLIMATE, a stacked kernel learner integrating multimodal genomic data and pathway knowledge. Plos Computational Biology. 17: e1008878. PMID 33861732 DOI: 10.1371/journal.pcbi.1008878  0.41
2020 Guan X, Sun D, Lu E, Urrutia JA, Reiter RE, Rettig M, Evans CP, Lara P, Gleave M, Beer TM, Thomas GV, Huang J, Aggarwal RR, Quigley DA, Foye A, ... ... Stuart JM, et al. Copy Number Loss of 17q22 Is Associated with Enzalutamide Resistance and Poor Prognosis in Metastatic Castration-Resistant Prostate Cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 32727885 DOI: 10.1158/1078-0432.Ccr-19-2303  0.341
2020 Rheinbay E, Nielsen MM, Abascal F, Wala JA, Shapira O, Tiao G, Hornshøj H, Hess JM, Juul RI, Lin Z, Feuerbach L, Sabarinathan R, Madsen T, Kim J, Mularoni L, ... ... Stuart JM, et al. Analyses of non-coding somatic drivers in 2,658 cancer whole genomes. Nature. 578: 102-111. PMID 32025015 DOI: 10.1038/s41586-020-1965-x  0.316
2020 Salcedo A, Tarabichi M, Espiritu SMG, Deshwar AG, David M, Wilson NM, Dentro S, Wintersinger JA, Liu LY, Ko M, Sivanandan S, Zhang H, Zhu K, Ou Yang TH, Chilton JM, ... ... Stuart JM, et al. A community effort to create standards for evaluating tumor subclonal reconstruction. Nature Biotechnology. 38: 97-107. PMID 31919445 DOI: 10.1038/S41587-019-0364-Z  0.346
2020 Haan D, Tao R, Friedl V, Anastopoulos IN, Wong CK, Weinstein AS, Stuart JM. Using Transcriptional Signatures to Find Cancer Drivers with LURE. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 25: 343-354. PMID 31797609  0.373
2019 Ding H, Blair A, Yang Y, Stuart JM. Biological process activity transformation of single cell gene expression for cross-species alignment. Nature Communications. 10: 4899. PMID 31653878 DOI: 10.1038/S41467-019-12924-W  0.309
2019 Ellrott K, Buchanan A, Creason A, Mason M, Schaffter T, Hoff B, Eddy J, Chilton JM, Yu T, Stuart JM, Saez-Rodriguez J, Stolovitzky G, Boutros PC, Guinney J. Reproducible biomedical benchmarking in the cloud: lessons from crowd-sourced data challenges. Genome Biology. 20: 195. PMID 31506093 DOI: 10.1186/S13059-019-1794-0  0.307
2019 Graim K, Friedl V, Houlahan KE, Stuart JM. PLATYPUS: A Multiple-View Learning Predictive Framework for Cancer Drug Sensitivity Prediction. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 24: 136-147. PMID 30864317  0.728
2018 Newton Y, Rassekh SR, Deyell RJ, Shen Y, Jones MR, Dunham C, Yip S, Leelakumari S, Zhu J, McColl D, Swatloski T, Salama SR, Ng T, Hendson G, Lee AF, ... ... Stuart JM, et al. Comparative RNA-Sequencing Analysis Benefits a Pediatric Patient With Relapsed Cancer. Jco Precision Oncology. 2. PMID 31372595 DOI: 10.1200/PO.17.00198  0.307
2018 Lee AY, Ewing AD, Ellrott K, Hu Y, Houlahan KE, Bare JC, Espiritu SMG, Huang V, Dang K, Chong Z, Caloian C, Yamaguchi TN, Kellen MR, Chen K, ... ... Stuart JM, et al. Combining accurate tumor genome simulation with crowdsourcing to benchmark somatic structural variant detection. Genome Biology. 19: 188. PMID 30400818 DOI: 10.1186/S13059-018-1539-5  0.376
2018 Quigley DA, Dang HX, Zhao SG, Lloyd P, Aggarwal R, Alumkal JJ, Foye A, Kothari V, Perry MD, Bailey AM, Playdle D, Barnard TJ, Zhang L, Zhang J, Youngren JF, ... ... Stuart JM, et al. Genomic Hallmarks and Structural Variation in Metastatic Prostate Cancer. Cell. 175: 889. PMID 30340047 DOI: 10.1016/J.Cell.2018.10.019  0.366
2018 Bailey MH, Tokheim C, Porta-Pardo E, Sengupta S, Bertrand D, Weerasinghe A, Colaprico A, Wendl MC, Kim J, Reardon B, Kwok-Shing Ng P, Jeong KJ, Cao S, Wang Z, Gao J, ... ... Stuart J, et al. Comprehensive Characterization of Cancer Driver Genes and Mutations. Cell. 174: 1034-1035. PMID 30096302 DOI: 10.1016/J.Cell.2018.07.034  0.359
2018 Quigley DA, Dang HX, Zhao SG, Lloyd P, Aggarwal R, Alumkal JJ, Foye A, Kothari V, Perry MD, Bailey AM, Playdle D, Barnard TJ, Zhang L, Zhang J, Youngren JF, ... ... Stuart JM, et al. Genomic Hallmarks and Structural Variation in Metastatic Prostate Cancer. Cell. PMID 30033370 DOI: 10.1016/J.Cell.2018.06.039  0.41
2018 Bailey MH, Tokheim C, Porta-Pardo E, Sengupta S, Bertrand D, Weerasinghe A, Colaprico A, Wendl MC, Kim J, Reardon B, Ng PK, Jeong KJ, Cao S, Wang Z, Gao J, ... ... Stuart J, et al. Comprehensive Characterization of Cancer Driver Genes and Mutations. Cell. 173: 371-385.e18. PMID 29625053 DOI: 10.1016/J.Cell.2018.02.060  0.33
2018 Malta TM, Sokolov A, Gentles AJ, Burzykowski T, Poisson L, Weinstein JN, Kamińska B, Huelsken J, Omberg L, Gevaert O, Colaprico A, Czerwińska P, Mazurek S, Mishra L, Heyn H, ... ... Stuart JM, et al. Machine Learning Identifies Stemness Features Associated with Oncogenic Dedifferentiation. Cell. 173: 338-354.e15. PMID 29625051 DOI: 10.1016/J.Cell.2018.03.034  0.352
2018 Ding L, Bailey MH, Porta-Pardo E, Thorsson V, Colaprico A, Bertrand D, Gibbs DL, Weerasinghe A, Huang KL, Tokheim C, Cortés-Ciriano I, Jayasinghe R, Chen F, Yu L, Sun S, ... ... Stuart JM, et al. Perspective on Oncogenic Processes at the End of the Beginning of Cancer Genomics. Cell. 173: 305-320.e10. PMID 29625049 DOI: 10.1016/J.Cell.2018.03.033  0.412
2018 Hoadley KA, Yau C, Hinoue T, Wolf DM, Lazar AJ, Drill E, Shen R, Taylor AM, Cherniack AD, Thorsson V, Akbani R, Bowlby R, Wong CK, Wiznerowicz M, Sanchez-Vega F, ... ... Stuart JM, et al. Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer. Cell. 173: 291-304.e6. PMID 29625048 DOI: 10.1016/J.Cell.2018.03.022  0.399
2018 Sendorek DH, Caloian C, Ellrott K, Bare JC, Yamaguchi TN, Ewing AD, Houlahan KE, Norman TC, Margolin AA, Stuart JM, Boutros PC. Germline contamination and leakage in whole genome somatic single nucleotide variant detection. Bmc Bioinformatics. 19: 28. PMID 29385983 DOI: 10.1186/S12859-018-2046-0  0.391
2018 Malta TM, Sokolov A, Gentles AJ, Burzykowski T, Poisson L, Weinstein J, Kamińska B, Huelsken J, Omberg L, Gevaert O, Colaprico A, Czerwińska P, Mazurek S, Mishra L, Heyn H, ... ... Stuart JM, et al. Abstract LB-373: Comprehensive analysis of cancer stemness Cancer Research. 78. DOI: 10.1158/1538-7445.Am2018-Lb-373  0.419
2017 Carlin DE, Paull EO, Graim K, Wong CK, Bivol A, Ryabinin P, Ellrott K, Sokolov A, Stuart JM. Prophetic Granger Causality to infer gene regulatory networks. Plos One. 12: e0170340. PMID 29211761 DOI: 10.1371/Journal.Pone.0170340  0.74
2017 Newton Y, Novak AM, Swatloski T, McColl DC, Chopra S, Graim K, Weinstein AS, Baertsch R, Salama SR, Ellrott K, Chopra M, Goldstein TC, Haussler D, Morozova O, Stuart JM. TumorMap: Exploring the Molecular Similarities of Cancer Samples in an Interactive Portal. Cancer Research. 77: e111-e114. PMID 29092953 DOI: 10.1158/0008-5472.Can-17-0580  0.738
2017 Niepel M, Hafner M, Duan Q, Wang Z, Paull EO, Chung M, Lu X, Stuart JM, Golub TR, Subramanian A, Ma'ayan A, Sorger PK. Common and cell-type specific responses to anti-cancer drugs revealed by high throughput transcript profiling. Nature Communications. 8: 1186. PMID 29084964 DOI: 10.1038/S41467-017-01383-W  0.334
2017 Gönen M, Weir BA, Cowley GS, Vazquez F, Guan Y, Jaiswal A, Karasuyama M, Uzunangelov V, Wang T, Tsherniak A, Howell S, Marbach D, Hoff B, Norman TC, Airola A, ... ... Stuart JM, et al. A Community Challenge for Inferring Genetic Predictors of Gene Essentialities through Analysis of a Functional Screen of Cancer Cell Lines. Cell Systems. PMID 28988802 DOI: 10.1016/J.Cels.2017.09.004  0.746
2017 Farshidfar F, Zheng S, Gingras MC, Newton Y, Shih J, Robertson AG, Hinoue T, Hoadley KA, Gibb EA, Roszik J, Covington KR, Wu CC, Shinbrot E, Stransky N, Hegde A, ... ... Stuart JM, et al. Integrative Genomic Analysis of Cholangiocarcinoma Identifies Distinct IDH-Mutant Molecular Profiles. Cell Reports. 19: 2878-2880. PMID 28658632 DOI: 10.1016/J.Celrep.2017.06.008  0.329
2017 Graim K, Liu TT, Achrol AS, Paull EO, Newton Y, Chang SD, Harsh GR, Cordero SP, Rubin DL, Stuart JM. Revealing cancer subtypes with higher-order correlations applied to imaging and omics data. Bmc Medical Genomics. 10: 20. PMID 28359308 DOI: 10.1186/S12920-017-0256-3  0.739
2017 Morozova O, Newton Y, Shah AT, Beale H, Lam DL, Vivian J, Bjork I, Goldstein T, Stuart J, Salama S, Sweet-Cordero EA, Haussler D. Abstract 4890: A pan-cancer analysis framework for incorporating gene expression information into clinical interpretation of pediatric cancer genomic data Cancer Research. 77: 4890-4890. DOI: 10.1158/1538-7445.Am2017-4890  0.397
2017 Beale H, Lam DL, Vivian J, Newton Y, Shah AT, Bjork I, Goldstein T, Brooks AN, Stuart J, Salama S, Sweet-Cordero EA, Haussler D, Morozova O. Abstract 2466: Identifying confidently measured genes in single pediatric cancer patient samples using RNA sequencing Cancer Research. 77: 2466-2466. DOI: 10.1158/1538-7445.Am2017-2466  0.304
2016 Aggarwal R, Beer TM, Gleave M, Stuart JM, Rettig M, Evans CP, Youngren J, Alumkal JJ, Huang J, Thomas G, Witte O, Small EJ. Targeting Adaptive Pathways in Metastatic Treatment-Resistant Prostate Cancer: Update on the Stand Up 2 Cancer/Prostate Cancer Foundation-Supported West Coast Prostate Cancer Dream Team. European Urology Focus. 2: 469-471. PMID 28723508 DOI: 10.1016/J.Euf.2016.10.011  0.387
2016 Cordero P, Stuart JM. TRACING CO-REGULATORY NETWORK DYNAMICS IN NOISY, SINGLE-CELL TRANSCRIPTOME TRAJECTORIES. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 22: 576-587. PMID 27897008 DOI: 10.1142/9789813207813_0053  0.314
2016 Drake JM, Paull EO, Graham NA, Lee JK, Smith BA, Titz B, Stoyanova T, Faltermeier CM, Uzunangelov V, Carlin DE, Fleming DT, Wong CK, Newton Y, Sudha S, Vashisht AA, ... ... Stuart JM, et al. Phosphoproteome Integration Reveals Patient-Specific Networks in Prostate Cancer. Cell. PMID 27499020 DOI: 10.1016/J.Cell.2016.07.007  0.447
2016 Waltman PH, Guo J, Reistetter EN, Purvine S, Ansong CK, van Baren MJ, Wong CH, Wei CL, Smith RD, Callister SJ, Stuart JM, Worden AZ. Identifying Aspects of the Post-Transcriptional Program Governing the Proteome of the Green Alga Micromonas pusilla. Plos One. 11: e0155839. PMID 27434306 DOI: 10.1371/Journal.Pone.0155839  0.32
2016 Si H, Lu H, Yang X, Mattox A, Jang M, Bian Y, Sano E, Viadiu H, Yan B, Yau C, Ng S, Lee SK, Romano RA, Davis S, Walker RL, ... ... Stuart JM, et al. TNF-α modulates genome-wide redistribution of ΔNp63α/TAp73 and NF-κB cREL interactive binding on TP53 and AP-1 motifs to promote an oncogenic gene program in squamous cancer. Oncogene. PMID 27132513 DOI: 10.1038/Onc.2016.112  0.393
2016 Lee JK, Phillips JW, Smith BA, Park JW, Stoyanova T, McCaffrey EF, Baertsch R, Sokolov A, Meyerowitz JG, Mathis C, Cheng D, Stuart JM, Shokat KM, Gustafson WC, Huang J, et al. N-Myc Drives Neuroendocrine Prostate Cancer Initiated from Human Prostate Epithelial Cells. Cancer Cell. 29: 536-47. PMID 27050099 DOI: 10.1016/J.Ccell.2016.03.001  0.317
2016 Sokolov A, Carlin DE, Paull EO, Baertsch R, Stuart JM. Pathway-Based Genomics Prediction using Generalized Elastic Net. Plos Computational Biology. 12: e1004790. PMID 26960204 DOI: 10.1371/Journal.Pcbi.1004790  0.441
2016 Hill SM, Heiser LM, Cokelaer T, Unger M, Nesser NK, Carlin DE, Zhang Y, Sokolov A, Paull EO, Wong CK, Graim K, Bivol A, Wang H, Zhu F, Afsari B, ... ... Stuart JM, et al. Inferring causal molecular networks: empirical assessment through a community-based effort. Nature Methods. PMID 26901648 DOI: 10.1038/Nmeth.3773  0.719
2016 Liu TT, Achrol AS, Mitchell LA, Du WA, Loya JJ, Rodriguez SA, Feroze A, Westbroek EM, Yeom KW, Stuart JM, Chang SD, Harsh GR, Rubin DL. Computational Identification of Tumor Anatomic Location Associated with Survival in 2 Large Cohorts of Human Primary Glioblastomas. Ajnr. American Journal of Neuroradiology. PMID 26744442 DOI: 10.3174/Ajnr.A4631  0.313
2016 Aggarwal RR, Youngren J, Sokolov A, Huang J, Thomas GV, True LD, Foye A, Alumkal JJ, Ryan CJ, Beer TM, Evans CP, Gleave M, Rettig M, Stuart JM, Lara P, et al. Persistence of AR signaling in small cell neuroendocrine prostate cancer (SCNC) and intermediate atypical carcinoma (IAC): Results from the SU2C/PCF/AACR West Coast Prostate Cancer Dream Team (WCDT). Journal of Clinical Oncology. 34: 5045-5045. DOI: 10.1200/Jco.2016.34.15_Suppl.5045  0.328
2016 Morozova O, Newton Y, Cline M, Yip S, Rao A, Stuart J, Goldstein T, Salama S, Deyell R, Rassekh SR, Haussler D. Abstract PR14: Harnessing the power of big data to advance pediatric cancer care Cancer Research. 76. DOI: 10.1158/1538-7445.Pedca15-Pr14  0.34
2016 Newton Y, Novak A, Swatlowski T, Chopra S, Salama S, Morozova O, Haussler D, Stuart J. Abstract LB-290: UCSC TumorMap: Exploring cancer signatures on an interactive dynamic landscape Cancer Research. 76. DOI: 10.1158/1538-7445.Am2016-Lb-290  0.48
2016 Drake JM, Paull EO, Graham NA, Lee JK, Smith BA, Stoyanova T, Faltermeier CM, Carlin DE, Vashisht A, Huang J, Wohlschlegel JA, Graeber TG, Witte ON, Stuart JM. Abstract 3882: Patient-specific druggable networks in lethal prostate cancer through proteome-guided multi-omic integration Cancer Research. 76: 3882-3882. DOI: 10.1158/1538-7445.Am2016-3882  0.448
2016 Weinstein JN, Lerner SP, Kwiatkowski DJ, Getz G, Kim J, Al-ahmadie HA, Cherniack AD, Guo G, Akbani R, Hoadley KA, Kim WY, Robertson G, Mungall AJ, Hinoue T, Laird PW, ... ... Stuart JM, et al. Abstract 128: Comprehensive molecular characterization of 412 muscle-invasive urothelial bladder carcinomas: final analysis of The Cancer Genome Atlas (TCGA) project Cancer Research. 76: 128-128. DOI: 10.1158/1538-7445.Am2016-128  0.438
2015 Smith BA, Sokolov A, Uzunangelov V, Baertsch R, Newton Y, Graim K, Mathis C, Cheng D, Stuart JM, Witte ON. A basal stem cell signature identifies aggressive prostate cancer phenotypes. Proceedings of the National Academy of Sciences of the United States of America. PMID 26460041 DOI: 10.1073/Pnas.1518007112  0.731
2015 Paten B, Diekhans M, Druker BJ, Friend S, Guinney J, Gassner N, Guttman M, James Kent W, Mantey P, Margolin AA, Massie M, Novak AM, Nothaft F, Pachter L, Patterson D, ... ... Stuart JM, et al. The NIH BD2K center for big data in translational genomics. Journal of the American Medical Informatics Association : Jamia. PMID 26174866 DOI: 10.1093/Jamia/Ocv047  0.338
2015 Creixell P, Reimand J, Haider S, Wu G, Shibata T, Vazquez M, Mustonen V, Gonzalez-Perez A, Pearson J, Sander C, Raphael BJ, Marks DS, Ouellette BFF, Valencia A, Bader GD, ... ... Stuart JM, et al. Pathway and network analysis of cancer genomes. Nature Methods. 12: 615-621. PMID 26125594 DOI: 10.1038/Nmeth.3440  0.375
2015 Ewing AD, Houlahan KE, Hu Y, Ellrott K, Caloian C, Yamaguchi TN, Bare JC, P'ng C, Waggott D, Sabelnykova VY, Kellen MR, Norman TC, Haussler D, Friend SH, ... ... Stuart JM, et al. Combining tumor genome simulation with crowdsourcing to benchmark somatic single-nucleotide-variant detection. Nature Methods. PMID 25984700 DOI: 10.1038/Nmeth.3407  0.385
2015 Youngren JF, Foye A, Thomas G, Stuart JM, Goldstein T, Robert B, Bivol A, Sokolov A, Ryan CJ, Pourmand N, Beer TM, Evans CP, Lara P, Gleave ME, Chi KN, et al. Abstract A12: Identification of pathways associated with abiraterone resistance in metastatic castration resistant prostate cancer: Preliminary results from the SU2C/AACR West Coast Prostate Cancer Dream Team Clinical Cancer Research. 21. DOI: 10.1158/1557-3265.Pms14-A12  0.415
2015 Lee JK, Smith BA, Phillips JW, Park J, Stoyanova TI, Baertsch R, Sokolov A, Mathis C, Cheng D, Stuart JM, Huang J, Witte ON. Abstract A28: N-Myc drives small cell neuroendocrine cancer initiated from human prostate basal cells Molecular Cancer Research. 13. DOI: 10.1158/1557-3125.Myc15-A28  0.359
2015 Uzunangelov V, Paull E, Chopra S, Carlin D, Bivol A, Ellrott K, Graim K, Newton Y, Ng S, Sokolov A, Stuart J. Abstract PR10: Multiple Pathway Learning accurately predicts gene essentiality in the Cancer Cell Line Encyclopedia Cancer Research. 75. DOI: 10.1158/1538-7445.Transcagen-Pr10  0.498
2015 Graim K, Newton Y, Bivol A, Sokolov A, Ellrott K, Baertsch R, Stuart J. Abstract A2-64: A signature catalog to classify tumor mixtures: Application to recognition of metastatic disease in prostate cancer Cancer Research. 75. DOI: 10.1158/1538-7445.Transcagen-A2-64  0.428
2015 Baertsch R, Wong C, Youngren J, Stuart J, Small E, Goldstein T. Abstract A1-46: Using Medbook Workbench to create evidence streams to guide medical decisions Cancer Research. 75. DOI: 10.1158/1538-7445.Transcagen-A1-46  0.36
2015 Uzunangelov V, Paull E, Chopra S, Carlin D, Bivol A, Ellrott K, Graim K, Newton Y, Ng S, Sokolov A, Stuart J. Abstract PR02: Multiple Pathway Learning accurately predicts gene essentiality in the Cancer Cell Line Encyclopedia Cancer Research. 75. DOI: 10.1158/1538-7445.Compsysbio-Pr02  0.494
2015 Ng S, Benz C, Haussler D, Stuart JM. Abstract B1-38: PARADIGM-SHIFT: Predicts the functional impact of ‘driver modules’ in multiple cancers using pathway impact analysis Cancer Research. 75. DOI: 10.1158/1538-7445.Compsysbio-B1-38  0.47
2015 Morozova O, Newton Y, Cline M, Zhu J, Learned K, Stuart J, Salama S, Arceci R, Haussler D. Abstract LB-212: Treehouse Childhood Cancer Project: a resource for sharing and multiple cohort analysis of pediatric cancer genomics data Cancer Research. 75. DOI: 10.1158/1538-7445.Am2015-Lb-212  0.347
2015 Woodward J, King C, Coleman D, Lisac R, Schwartzman J, Wang N, Gleave M, Gray J, Thomas G, Beer TM, Hook KV, Baertsch R, Goldstein T, Stuart J, Gao L, et al. Abstract 731: Integrative genomic analysis to identify emergent enzalutamide resistance mechanisms in castration-resistant prostate cancer Cancer Research. 75: 731-731. DOI: 10.1158/1538-7445.Am2015-731  0.32
2015 Weinstein JN, Kim J, Creighton CJ, Akbani R, Hoadley KA, Kim WY, Morgan MB, Hinoue T, Cherniack A, Su X, Mungall AJ, Ryan MC, Bajorin DF, Rosenberg JE, Czerniak B, ... ... Stuart JM, et al. Abstract 2969: Progress in The Cancer Genome Atlas bladder cancer project Cancer Research. 75: 2969-2969. DOI: 10.1158/1538-7445.Am2015-2969  0.334
2014 Small EJ, Youngren J, Alumkal J, Evans C, Ryan CJ, Lara P, Beer T, Witte O, Baertsch R, Stuart J. 760PDNEUROENDOCRINE PROSTATE CANCER (NEPC) IN PATIENTS (PTS) WITH METASTATIC CASTRATION RESISTANT PROSTATE CANCER (MCRPC) RESISTANT TO ABIRATERONE (ABI) OR ENZALUTAMIDE (ENZ): PRELIMINARY RESULTS FROM THE SU2C/PCF/AACR WEST COAST PROSTATE CANCER DREAM TEAM (WCDT). Annals of Oncology : Official Journal of the European Society For Medical Oncology. 25: iv258. PMID 28172078 DOI: 10.1093/Annonc/Mdu336.8  0.373
2014 Radenbaugh AJ, Ma S, Ewing A, Stuart JM, Collisson EA, Zhu J, Haussler D. RADIA: RNA and DNA integrated analysis for somatic mutation detection Plos One. 9. PMID 25405470 DOI: 10.1371/Journal.Pone.0111516  0.329
2014 Boutros PC, Margolin AA, Stuart JM, Califano A, Stolovitzky G. Toward better benchmarking: challenge-based methods assessment in cancer genomics. Genome Biology. 15: 462. PMID 25314947 DOI: 10.1186/S13059-014-0462-7  0.394
2014 Hoadley KA, Yau C, Wolf DM, Cherniack AD, Tamborero D, Ng S, Leiserson MD, Niu B, McLellan MD, Uzunangelov V, Zhang J, Kandoth C, Akbani R, Shen H, Omberg L, ... ... Stuart JM, et al. Multiplatform analysis of 12 cancer types reveals molecular classification within and across tissues of origin. Cell. 158: 929-44. PMID 25109877 DOI: 10.1016/J.Cell.2014.06.049  0.453
2014 Yuan Y, Van Allen EM, Omberg L, Wagle N, Amin-Mansour A, Sokolov A, Byers LA, Xu Y, Hess KR, Diao L, Han L, Huang X, Lawrence MS, Weinstein JN, Stuart JM, et al. Assessing the clinical utility of cancer genomic and proteomic data across tumor types. Nature Biotechnology. 32: 644-52. PMID 24952901 DOI: 10.1038/Nbt.2940  0.36
2014 Boutros PC, Ewing AD, Ellrott K, Norman TC, Dang KK, Hu Y, Kellen MR, Suver C, Bare JC, Stein LD, Spellman PT, Stolovitzky G, Friend SH, Margolin AA, Stuart JM. Global optimization of somatic variant identification in cancer genomes with a global community challenge. Nature Genetics. 46: 318-9. PMID 24675517 DOI: 10.1038/Ng.2932  0.351
2014 Small EJ, Youngren J, Beer TM, Ryan CJ, Thomas G, Pourmand N, Reiter RE, Alumkal JJ, Stuart JM, Evans CP, Gleave ME, Chi KN, Toschi A, Foye A, Lara P, et al. The molecular and pathway characterization of patients with metastatic castration resistant prostate cancer (mCRPC) refractory to therapy with abiraterone acetate or enzalutamide: Preliminary results from the SU2C/PCF/AACR West Coast Prostate Cancer Dream Team (WCDT). Journal of Clinical Oncology. 32: 79-79. DOI: 10.1200/Jco.2014.32.4_Suppl.79  0.378
2014 Weinstein JN, Kim J, Creighton CJ, Akbani R, Hoadley KA, Kim WY, Morgan MB, Hinoue T, Rosenberg JE, Bajorin DF, Hansel DE, Al-Ahmadie H, Gordenin D, Stuart JM, Robertson G, et al. Comprehensive molecular profiling of urothelial bladder cancer at the DNA, RNA, and protein levels: A TCGA project. Journal of Clinical Oncology. 32: 4509-4509. DOI: 10.1200/Jco.2014.32.15_Suppl.4509  0.417
2014 Bivol A, Baertsch R, Sokolov A, Paull E, Newton Y, Goldstein TC, Foye A, Pourmand N, Youngren J, Parulkar R, Lopez A, de Vere White R, Alumkal JJ, Toschi A, Beer TM, ... ... Stuart JM, et al. Pathway-based signature analysis of RNA-seq data to reveal new targetable avenues for metastatic castration-resistant prostate cancer (mCRPC) patients (pts): Preliminary results from the SU2C/PCF/AACR West Coast Prostate Cancer Dream Team (WCDT). Journal of Clinical Oncology. 32: 11078-11078. DOI: 10.1200/Jco.2014.32.15_Suppl.11078  0.359
2014 Weinstein JN, Kim J, Creighton CJ, Akbani R, Hoadley KA, Kim WY, Morgan MB, Hinoue T, Cherniack A, Su X, Mungall AJ, Ryan MC, Rosenberg JE, Bajorin DF, Czerniak B, ... ... Stuart JM, et al. Abstract 987: Comprehensive characterization of urothelial bladder cancer: a TCGA Project update Cancer Research. 74: 987-987. DOI: 10.1158/1538-7445.Am2014-987  0.421
2014 Bivol A, Graim K, Paull E, Carlin D, Baertsch R, Sokolov A, Stuart J. Abstract 4177: Identification of pathways relevant for metastatic site prediction in prostate cancer Cancer Research. 74: 4177-4177. DOI: 10.1158/1538-7445.Am2014-4177  0.327
2014 Wolf DM, Fan C, Hoadley KA, Yau C, Sokolov A, Stuart J, Perou C, Veer Lv'. Abstract 360: Thousands of published cancer signatures and pathways can be collapsed into a handful of non-redundant gene programs: a TCGA pan-cancer analysis Cancer Research. 74: 360-360. DOI: 10.1158/1538-7445.Am2014-360  0.347
2013 Omberg L, Ellrott K, Yuan Y, Kandoth C, Wong C, Kellen MR, Friend SH, Stuart J, Liang H, Margolin AA. Enabling transparent and collaborative computational analysis of 12 tumor types within The Cancer Genome Atlas. Nature Genetics. 45: 1121-6. PMID 24071850 DOI: 10.1038/Ng.2761  0.305
2013 Weinstein JN, Collisson EA, Mills GB, Shaw KR, Ozenberger BA, Ellrott K, Shmulevich I, Sander C, Stuart JM. The Cancer Genome Atlas Pan-Cancer analysis project. Nature Genetics. 45: 1113-20. PMID 24071849 DOI: 10.1038/Ng.2764  0.441
2013 Paull EO, Carlin DE, Niepel M, Sorger PK, Haussler D, Stuart JM. Discovering causal pathways linking genomic events to transcriptional states using Tied Diffusion Through Interacting Events (TieDIE). Bioinformatics (Oxford, England). 29: 2757-64. PMID 23986566 DOI: 10.1093/Bioinformatics/Btt471  0.465
2013 Gonzalez-Perez A, Mustonen V, Reva B, Ritchie GR, Creixell P, Karchin R, Vazquez M, Fink JL, Kassahn KS, Pearson JV, Bader GD, Boutros PC, Muthuswamy L, Ouellette BF, Reimand J, ... ... Stuart JM, et al. Computational approaches to identify functional genetic variants in cancer genomes. Nature Methods. 10: 723-9. PMID 23900255 DOI: 10.1038/Nmeth.2562  0.303
2013 Wong CK, Vaske CJ, Ng S, Sanborn JZ, Benz SC, Haussler D, Stuart JM. The UCSC Interaction Browser: multidimensional data views in pathway context. Nucleic Acids Research. 41: W218-24. PMID 23748957 DOI: 10.1093/Nar/Gkt473  0.42
2013 Goldstein TC, Paull EO, Ellis MJ, Stuart JM. Molecular pathways: extracting medical knowledge from high-throughput genomic data. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 3114-20. PMID 23430023 DOI: 10.1158/1078-0432.Ccr-12-2093  0.435
2013 Goldman M, Craft B, Swatloski T, Ellrott K, Cline M, Diekhans M, Ma S, Wilks C, Stuart J, Haussler D, Zhu J. The UCSC Cancer Genomics Browser: update 2013. Nucleic Acids Research. 41: D949-54. PMID 23109555 DOI: 10.1093/Nar/Gks1008  0.453
2013 Febbo PG, Goldstein TC, Baertsch R, Youngren J, Newton Y, Bivol A, Small EJ, Stuart JM. Identification of polo-like kinase 1 (PLK1) in aggressive prostate cancer by paradigm analysis. Journal of Clinical Oncology. 31: 5006-5006. DOI: 10.1200/Jco.2013.31.15_Suppl.5006  0.457
2013 Heiser LM, Shaw CA, Wang NJ, Grasso C, Anur P, Ng S, Goldstein T, Spellman PT, Stuart J, Osborne K, Gray J, Schiff R. Abstract 5238: Acquired therapeutic resistance is mediated by deregulation of multiple pathways. Cancer Research. 73: 5238-5238. DOI: 10.1158/1538-7445.Am2013-5238  0.363
2012 Ng S, Collisson EA, Sokolov A, Goldstein T, Gonzalez-Perez A, Lopez-Bigas N, Benz C, Haussler D, Stuart JM. PARADIGM-SHIFT predicts the function of mutations in multiple cancers using pathway impact analysis. Bioinformatics (Oxford, England). 28: i640-i646. PMID 22962493 DOI: 10.1093/Bioinformatics/Bts402  0.465
2012 Ellis MJ, Ding L, Shen D, Luo J, Suman VJ, Wallis JW, Van Tine BA, Hoog J, Goiffon RJ, Goldstein TC, Ng S, Lin L, Crowder R, Snider J, Ballman K, ... ... Stuart JM, et al. Whole-genome analysis informs breast cancer response to aromatase inhibition. Nature. 486: 353-60. PMID 22722193 DOI: 10.1038/Nature11143  0.394
2012 Heiser LM, Sadanandam A, Kuo WL, Benz SC, Goldstein TC, Ng S, Gibb WJ, Wang NJ, Ziyad S, Tong F, Bayani N, Hu Z, Billig JI, Dueregger A, Lewis S, ... ... Stuart JM, et al. Subtype and pathway specific responses to anticancer compounds in breast cancer. Proceedings of the National Academy of Sciences of the United States of America. 109: 2724-9. PMID 22003129 DOI: 10.1073/Pnas.1018854108  0.369
2012 Ellis MJ, Ding L, Shen D, Luo J, Suman VJ, Goiffon RJ, Wallis JW, Goldstein TC, Chen K, Allred DC, Leitch AM, Olson JA, Ota DM, Watson M, Piwnica-Worms D, ... ... Stuart JM, et al. Whole genome sequencing to characterize luminal-type breast cancer. Journal of Clinical Oncology. 30: 503-503. DOI: 10.1200/Jco.2012.30.15_Suppl.503  0.38
2012 Stuart J. Pathway-based analysis of mutation impact Bmc Proceedings. 6: 1-1. DOI: 10.1186/1753-6561-6-S6-O3  0.397
2012 Szeto CW, Sokolov A, Benz S, Stuart J, Haussler D. Abstract 5085: TopModel: An online resource for predictive models in cancer Cancer Research. 72: 5085-5085. DOI: 10.1158/1538-7445.Am2012-5085  0.472
2012 Ng S, Thusberg J, Benz S, Vaske C, Ellrott K, Zhu J, Yau C, Collisson E, Mooney S, Benz C, Haussler D, Stuart J. Abstract 2985: Predicting the impact of mutations in cancer using an integrated pathway approach Cancer Research. 72: 2985-2985. DOI: 10.1158/1538-7445.Am2012-2985  0.399
2011 Koeva M, Forsberg EC, Stuart JM. Computational integration of homolog and pathway gene module expression reveals general stemness signatures. Plos One. 6: e18968. PMID 21559491 DOI: 10.1371/Journal.Pone.0018968  0.339
2011 Tamble CM, St. Onge RP, Giaever G, Nislow C, Williams AG, Stuart JM, Lokey RS. The synthetic genetic interaction network reveals small molecules that target specific pathways in Sacchromyces cerevisiae Molecular Biosystems. 7: 2019-2030. PMID 21487606 DOI: 10.1039/C0Mb00298D  0.362
2011 Sanborn JZ, Benz SC, Craft B, Szeto C, Kober KM, Meyer L, Vaske CJ, Goldman M, Smith KE, Kuhn RM, Karolchik D, Kent WJ, Stuart JM, Haussler D, Zhu J. The UCSC Cancer Genomics Browser: update 2011. Nucleic Acids Research. 39: D951-9. PMID 21059681 DOI: 10.1093/Nar/Gkq1113  0.438
2011 Radenbaugh A, Sanborn JZ, Zerbino D, Wilks C, Stuart JM, Haussler D. Abstract 59: Identification of RNA editing events in cancer using high-throughput sequencing data Cancer Research. 71: 59-59. DOI: 10.1158/1538-7445.Am2011-59  0.377
2011 Zhu J, Sanborn JZ, Benz SC, Craft B, Szeto C, Kober KM, Goldman M, Meyer L, Vaske C, Collisson E, Stuart J, Haussler D. Abstract 4985: The UCSC Cancer Genomics Browser Cancer Research. 71: 4985-4985. DOI: 10.1158/1538-7445.Am2011-4985  0.447
2011 Ng S, Vaske C, Benz S, Durbin J, Szeto C, Heiser L, Wang N, Korkola J, Bayani N, Spellman P, Gray JW, Haussler D, Stuart J. Abstract 49: Constructing pathway based predictors of cancer clinical outcome Cancer Research. 71: 49-49. DOI: 10.1158/1538-7445.Am2011-49  0.483
2011 Szeto CW, Zhu J, Durbin J, Benz S, Vaske C, Stuart J, Haussler D. Abstract 43: Using matrix factorization to discover clinically-relevant molecular signatures across cancers Cancer Research. 71: 43-43. DOI: 10.1158/1538-7445.Am2011-43  0.439
2011 Stuart JM. Abstract CN07-04: Patient-specific pathway analysis using PARADIGM identifies key activities in multiple cancers. Molecular Cancer Therapeutics. 10. DOI: 10.1158/1535-7163.Targ-11-Cn07-04  0.462
2011 Yau C, Benz S, Sanborn J, Stuart J, Haussler D, Benz C. PD03-04: SuperPathway Analyses of Luminal and Basaloid Breast Cancers from the Cancer Genome Atlas (TCGA) Program. Cancer Research. 71. DOI: 10.1158/0008-5472.Sabcs11-Pd03-04  0.386
2011 Wolf D, Yau C, Benz S, Vaske C, Stuart J, Roy R, Olshen A, Boudreau A, Haussler D, Gray J, Spellman P, Davis S, Hylton N, Veer LV, Esserman L. P1-06-09: Patient-Specific Integrative Pathway Analysis Using PARADIGM Identifies Key Activities in I-SPY 1 Breast Cancer Patients (CALGB 150007/150012; ACRIN 6657). Cancer Research. 71. DOI: 10.1158/0008-5472.Sabcs11-P1-06-09  0.436
2010 House CD, Vaske CJ, Schwartz AM, Obias V, Frank B, Luu T, Sarvazyan N, Irby R, Strausberg RL, Hales TG, Stuart JM, Lee NH. Voltage-gated Na+ channel SCN5A is a key regulator of a gene transcriptional network that controls colon cancer invasion. Cancer Research. 70: 6957-67. PMID 20651255 DOI: 10.1158/0008-5472.Can-10-1169  0.432
2010 Vaske CJ, Benz SC, Sanborn JZ, Earl D, Szeto C, Zhu J, Haussler D, Stuart JM. Inference of patient-specific pathway activities from multi-dimensional cancer genomics data using PARADIGM. Bioinformatics (Oxford, England). 26: i237-45. PMID 20529912 DOI: 10.1093/Bioinformatics/Btq182  0.496
2010 Wang BD, Kline CL, Pastor DM, Olson TL, Frank B, Luu T, Sharma AK, Robertson G, Weirauch MT, Patierno SR, Stuart JM, Irby RB, Lee NH. Prostate apoptosis response protein 4 sensitizes human colon cancer cells to chemotherapeutic 5-FU through mediation of an NF kappaB and microRNA network. Molecular Cancer. 9: 98. PMID 20433755 DOI: 10.1186/1476-4598-9-98  0.404
2010 Hudson TJ, Anderson W, Artez A, Barker AD, Bell C, Bernabé RR, Bhan MK, Calvo F, Eerola I, Gerhard DS, Guttmacher A, Guyer M, Hemsley FM, Jennings JL, ... ... Stuart JM, et al. International network of cancer genome projects. Nature. 464: 993-8. PMID 20393554 DOI: 10.1038/Nature08987  0.425
2010 Forsberg EC, Passegué E, Prohaska SS, Wagers AJ, Koeva M, Stuart JM, Weissman IL. Molecular signatures of quiescent, mobilized and leukemia-initiating hematopoietic stem cells. Plos One. 5: e8785. PMID 20098702 DOI: 10.1371/Journal.Pone.0008785  0.325
2010 Benz SC, Vaske C, Ng S, Sanborn JZ, Zhu J, Haussler D, Stuart J. Abstract 4905: Patient-specific pathway analysis using PARADIGM identifies key activities in multiple cancers Cancer Research. 71: 4905-4905. DOI: 10.1158/1538-7445.Am2011-4905  0.484
2010 House C, Vaske C, Schwartz A, Obias V, Sarvazyan N, Hales T, Stuart J, Lee N. Abstract 5292: Role of voltage-gated Na+ channels in the metastatic potential of colon cancer cells Cancer Research. 70: 5292-5292. DOI: 10.1158/1538-7445.Am10-5292  0.382
2010 Christopher S, Benz S, Vaske C, Sanborn JZ, Zhu J, Stuart J, Haussler D. Abstract 2001: Non-negative matrix factorization (NMF) as a clinical classifier: An example with chemotherapy response in ovarian cancer Cancer Research. 70: 2001-2001. DOI: 10.1158/1538-7445.Am10-2001  0.386
2009 Vaske CJ, House C, Luu T, Frank B, Yeang CH, Lee NH, Stuart JM. A factor graph nested effects model to identify networks from genetic perturbations. Plos Computational Biology. 5: e1000274. PMID 19180177 DOI: 10.1371/Journal.Pcbi.1000274  0.44
2009 Cozen AE, Weirauch MT, Pollard KS, Bernick DL, Stuart JM, Lowe TM. Transcriptional map of respiratory versatility in the hyperthermophilic crenarchaeon Pyrobaculum aerophilum Journal of Bacteriology. 191: 782-794. PMID 19047344 DOI: 10.1128/Jb.00965-08  0.364
2009 Koeva M, Forsberg EC, Stuart JM. Core stemness mechanisms revealed through homology Bmc Bioinformatics. 10: O4. DOI: 10.1186/1471-2105-10-S13-O4  0.337
2008 Weirauch MT, Wong CK, Byrne AB, Stuart JM. Information-based methods for predicting gene function from systematic gene knock-downs. Bmc Bioinformatics. 9: 463. PMID 18959798 DOI: 10.1186/1471-2105-9-463  0.411
2007 Salomonis N, Hanspers K, Zambon AC, Vranizan K, Lawlor SC, Dahlquist KD, Doniger SW, Stuart J, Conklin BR, Pico AR. GenMAPP 2: new features and resources for pathway analysis. Bmc Bioinformatics. 8: 217. PMID 17588266 DOI: 10.1186/1471-2105-8-217  0.394
2007 Hu Z, Ng DM, Yamada T, Chen C, Kawashima S, Mellor J, Linghu B, Kanehisa M, Stuart JM, DeLisi C. VisANT 3.0: new modules for pathway visualization, editing, prediction and construction. Nucleic Acids Research. 35: W625-32. PMID 17586824 DOI: 10.1093/Nar/Gkm295  0.364
2007 Hu Z, Mellor J, Wu J, Kanehisa M, Stuart JM, DeLisi C. Towards zoomable multidimensional maps of the cell. Nature Biotechnology. 25: 547-54. PMID 17483841 DOI: 10.1038/Nbt1304  0.371
2007 Chen C, Weirauch MT, Powell CC, Zambon AC, Stuart JM. A search engine to identify pathway genes from expression data on multiple organisms. Bmc Systems Biology. 1: 20. PMID 17477880 DOI: 10.1186/1752-0509-1-20  0.395
2006 Park CS, Gong R, Stuart J, Tang S. Molecular network and chromosomal clustering of genes involved in synaptic plasticity in the hippocampus. Journal of Biological Chemistry. 281: 30195-30211. PMID 16873368 DOI: 10.1074/Jbc.M605876200  0.308
2003 Stuart JM, Segal E, Koller D, Kim SK. A gene-coexpression network for global discovery of conserved genetic modules. Science (New York, N.Y.). 302: 249-55. PMID 12934013 DOI: 10.1126/Science.1087447  0.574
2003 Owen AB, Stuart J, Mach K, Villeneuve AM, Kim S. A gene recommender algorithm to identify coexpressed genes in C. elegans. Genome Research. 13: 1828-37. PMID 12902378 DOI: 10.1101/Gr.1125403  0.504
2002 Roy PJ, Stuart JM, Lund J, Kim SK. Chromosomal clustering of muscle-expressed genes in Caenorhabditis elegans. Nature. 418: 975-9. PMID 12214599 DOI: 10.1038/Nature01012  0.512
2002 Hewett M, Oliver DE, Rubin DL, Easton KL, Stuart JM, Altman RB, Klein TE. PharmGKB: the Pharmacogenetics Knowledge Base. Nucleic Acids Research. 30: 163-5. PMID 11752281 DOI: 10.1093/Nar/30.1.163  0.318
2001 Kim SK, Lund J, Kiraly M, Duke K, Jiang M, Stuart JM, Eizinger A, Wylie BN, Davidson GS. A gene expression map for Caenorhabditis elegans. Science (New York, N.Y.). 293: 2087-92. PMID 11557892 DOI: 10.1126/Science.1061603  0.557
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