| Year |
Citation |
Score |
| 2020 |
Apostol CR, Hay M, Polt R. Glycopeptide drugs: A pharmacological dimension between “Small Molecules” and “Biologics” Peptides. 131: 170369. PMID 32673700 DOI: 10.1016/J.Peptides.2020.170369 |
0.361 |
|
| 2020 |
Bartlett MJ, So LY, Szabò L, Skinner DP, Parent KL, Heien ML, Vanderah TW, Polt R, Sherman SJ, Falk T. Highly-selective µ-opioid receptor antagonism does not block L-DOPA-induced dyskinesia in a rodent model. Bmc Research Notes. 13: 149. PMID 32164786 DOI: 10.1186/S13104-020-04994-7 |
0.333 |
|
| 2020 |
Burgess GE, Polt R, Rice KC, Jutkiewicz EM. Characterization of Delta Opioid Receptor Activity of MMP2200, a Mixed Efficacy Mu and Delta Opioid Receptor Agonist The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.05714 |
0.304 |
|
| 2017 |
Palos Pacheco R, Eismin RJ, Coss CS, Wang H, Maier RM, Polt R, Pemberton JE. Synthesis and Characterization of Four Diastereomers of Monorhamnolipids. Journal of the American Chemical Society. PMID 28301722 DOI: 10.1021/Jacs.7B00427 |
0.753 |
|
| 2016 |
Szabó LZ, Hanrahan DJ, Jones EM, Martin E, Pemberton JE, Polt R. Preparation of S-glycoside surfactants and cysteine thioglycosides using minimally competent Lewis acid catalysis. Carbohydrate Research. 422: 1-4. PMID 26795078 DOI: 10.1016/J.Carres.2015.12.008 |
0.333 |
|
| 2015 |
Jones EM, Polt R. CNS active O-linked glycopeptides. Frontiers in Chemistry. 3: 40. PMID 26157795 DOI: 10.3389/Fchem.2015.00040 |
0.375 |
|
| 2015 |
Lefever M, Li Y, Anglin B, Muthu D, Giuvelis D, Lowery JJ, Knapp BI, Bidlack JM, Bilsky EJ, Polt R. Structural Requirements for CNS Active Opioid Glycopeptides. Journal of Medicinal Chemistry. 58: 5728-41. PMID 26125201 DOI: 10.1021/Acs.Jmedchem.5B00014 |
0.78 |
|
| 2015 |
Stevenson GW, Luginbuhl A, Dunbar C, LaVigne J, Dutra J, Atherton P, Bell B, Cone K, Giuvelis D, Polt R, Streicher JM, Bilsky EJ. The mixed-action delta/mu opioid agonist MMP-2200 does not produce conditioned place preference but does maintain drug self-administration in rats, and induces in vitro markers of tolerance and dependence. Pharmacology, Biochemistry, and Behavior. 132: 49-55. PMID 25735493 DOI: 10.1016/J.Pbb.2015.02.022 |
0.302 |
|
| 2014 |
Li Y, St Louis L, Knapp BI, Muthu D, Anglin B, Giuvelis D, Bidlack JM, Bilsky EJ, Polt R. Can amphipathic helices influence the CNS antinociceptive activity of glycopeptides related to β-endorphin? Journal of Medicinal Chemistry. 57: 2237-46. PMID 24576160 DOI: 10.1021/Jm400879W |
0.793 |
|
| 2013 |
Wang H, Coss CS, Mudalige A, Polt RL, Pemberton JE. A PM-IRRAS investigation of monorhamnolipid orientation at the air-water interface. Langmuir : the Acs Journal of Surfaces and Colloids. 29: 4441-50. PMID 23406083 DOI: 10.1021/La3051725 |
0.749 |
|
| 2012 |
Mabrouk OS, Falk T, Sherman SJ, Kennedy RT, Polt R. CNS penetration of the opioid glycopeptide MMP-2200: a microdialysis study. Neuroscience Letters. 531: 99-103. PMID 23127847 DOI: 10.1016/J.Neulet.2012.10.029 |
0.364 |
|
| 2012 |
Lefever MR, Szabò LZ, Anglin B, Ferracane M, Hogan J, Cooney L, Polt R. Glycosylation of α-amino acids by sugar acetate donors with InBr3. Minimally competent Lewis acids. Carbohydrate Research. 351: 121-5. PMID 22342206 DOI: 10.1016/J.Carres.2012.01.008 |
0.77 |
|
| 2012 |
Li Y, Lefever MR, Muthu D, Bidlack JM, Bilsky EJ, Polt R. Opioid glycopeptide analgesics derived from endogenous enkephalins and endorphins. Future Medicinal Chemistry. 4: 205-26. PMID 22300099 DOI: 10.4155/Fmc.11.195 |
0.768 |
|
| 2012 |
Coss C, Carrocci T, Maier RM, Pemberton JE, Polt R. Minimally competent lewis acid catalysts: Indium(III) and bismuth(III) salts produce rhamnosides (=6-deoxymannosides) in high yield and purity Helvetica Chimica Acta. 95: 2652-2659. DOI: 10.1002/Hlca.201200528 |
0.763 |
|
| 2011 |
Yue X, Falk T, Zuniga LA, Szabò L, Porreca F, Polt R, Sherman SJ. Effects of the novel glycopeptide opioid agonist MMP-2200 in preclinical models of Parkinson's disease. Brain Research. 1413: 72-83. PMID 21840512 DOI: 10.1016/J.Brainres.2011.07.038 |
0.306 |
|
| 2011 |
Yeomans L, Muthu D, Lowery JJ, Martinez HN, Abrell L, Lin G, Strom K, Knapp BI, Bidlack JM, Bilsky EJ, Polt R. Phosphorylation of enkephalins: NMR and CD studies in aqueous and membrane-mimicking environments. Chemical Biology & Drug Design. 78: 749-56. PMID 21801311 DOI: 10.1111/J.1747-0285.2011.01203.X |
0.398 |
|
| 2011 |
Lowery JJ, Raymond TJ, Giuvelis D, Bidlack JM, Polt R, Bilsky EJ. In vivo characterization of MMP-2200, a mixed δ/μ opioid agonist, in mice. The Journal of Pharmacology and Experimental Therapeutics. 336: 767-78. PMID 21118955 DOI: 10.1124/Jpet.110.172866 |
0.329 |
|
| 2010 |
Keyari CM, Polt R, Nichol GS. (S)-Methyl 2-{(S)-2-[bis-(4-meth-oxy-phen-yl)methyl-idene-amino]-3-hy-droxy-propanamido}-3-methyl-butano-ate. Acta Crystallographica. Section E, Structure Reports Online. 67: o13-4. PMID 21522640 DOI: 10.1107/S1600536810049032 |
0.77 |
|
| 2010 |
Keyari CM, Polt R. Serine and threonine Schiff base esters react with β-anomeric peracetates in the presence of BF3·Et2O to produce β-glycosides Journal of Carbohydrate Chemistry. 29: 181-206. DOI: 10.1080/07328303.2010.508295 |
0.77 |
|
| 2010 |
SAMES D, POLT R. ChemInform Abstract: Piperidine Triols via Enantioselective Alkylation and Osmylation of Alanine Schiff Base Esters. Cheminform. 26: no-no. DOI: 10.1002/CHIN.199540222 |
0.542 |
|
| 2009 |
Keyari CM, Knapp BI, Bidlack JM, Lowey J, Bilsky EJ, Polt R. Glycosyl-enkephalins: synthesis and binding at the mu, delta & kappa opioid receptors. Antinociception in mice. Advances in Experimental Medicine and Biology. 611: 495-6. PMID 19400281 DOI: 10.1007/978-0-387-73657-0_214 |
0.774 |
|
| 2008 |
Do Carmo GP, Polt R, Bilsky EJ, Rice KC, Negus SS. Behavioral pharmacology of the mu/delta opioid glycopeptide MMP2200 in rhesus monkeys. The Journal of Pharmacology and Experimental Therapeutics. 326: 939-48. PMID 18511649 DOI: 10.1124/Jpet.108.138180 |
0.307 |
|
| 2007 |
Lowery JJ, Yeomans L, Keyari CM, Davis P, Porreca F, Knapp BI, Bidlack JM, Bilsky EJ, Polt R. Glycosylation improves the central effects of DAMGO. Chemical Biology & Drug Design. 69: 41-7. PMID 17313456 DOI: 10.1111/J.1747-0285.2007.00462.X |
0.792 |
|
| 2005 |
Dhanasekaran M, Polt R. New prospects for glycopeptide based analgesia: glycoside-induced penetration of the blood-brain barrier. Current Drug Delivery. 2: 59-73. PMID 16305409 DOI: 10.2174/1567201052772843 |
0.378 |
|
| 2005 |
Polt R, Dhanasekaran M, Keyari CM. Glycosylated neuropeptides: a new vista for neuropsychopharmacology? Medicinal Research Reviews. 25: 557-85. PMID 16075406 DOI: 10.1002/Med.20039 |
0.787 |
|
| 2005 |
Dhanasekaran M, Palian MM, Alves I, Yeomans L, Keyari CM, Davis P, Bilsky EJ, Egleton RD, Yamamura HI, Jacobsen NE, Tollin G, Hruby VJ, Porreca F, Polt R. Glycopeptides related to beta-endorphin adopt helical amphipathic conformations in the presence of lipid bilayers. Journal of the American Chemical Society. 127: 5435-48. PMID 15826181 DOI: 10.1021/Ja0432158 |
0.757 |
|
| 2005 |
Egleton RD, Bilsky EJ, Tollin G, Dhanasekaran M, Lowery J, Alves I, Davis P, Porreca F, Yamamura HI, Yeomans L, Keyari CM, Polt R. Biousian glycopeptides penetrate the blood-brain barrier Tetrahedron Asymmetry. 16: 65-75. DOI: 10.1016/J.Tetasy.2004.11.038 |
0.793 |
|
| 2004 |
Elmagbari NO, Egleton RD, Palian MM, Lowery JJ, Schmid WR, Davis P, Navratilova E, Dhanasekaran M, Keyari CM, Yamamura HI, Porreca F, Hruby VJ, Polt R, Bilsky EJ. Antinociceptive structure-activity studies with enkephalin-based opioid glycopeptides. The Journal of Pharmacology and Experimental Therapeutics. 311: 290-7. PMID 15166257 DOI: 10.1124/Jpet.104.069393 |
0.78 |
|
| 2004 |
Slavish JP, Friel DK, Oland LA, Polt R. New PDMP analogues inhibit process outgrowth in an insect cell line. Bioorganic & Medicinal Chemistry Letters. 14: 1487-90. PMID 15006387 DOI: 10.1016/J.Bmcl.2004.01.013 |
0.732 |
|
| 2003 |
Palian MM, Boguslavsky VI, O'Brien DF, Polt R. Glycopeptide-membrane interactions: glycosyl enkephalin analogues adopt turn conformations by NMR and CD in amphipathic media. Journal of the American Chemical Society. 125: 5823-31. PMID 12733923 DOI: 10.1021/Ja0268635 |
0.798 |
|
| 2003 |
Polt R, Kelly BD, Dangel BD, Tadikonda UB, Ross RE, Raitsimring AM, Astashkin AV. Optically active 4- and 5-coordinate transition metal complexes of bifurcated dipeptide Schiff bases. Inorganic Chemistry. 42: 566-74. PMID 12693240 DOI: 10.1021/Ic025996O |
0.702 |
|
| 2001 |
Egleton RD, Mitchell SA, Huber JD, Palian MM, Polt R, Davis TP. Improved blood-brain barrier penetration and enhanced analgesia of an opioid peptide by glycosylation. The Journal of Pharmacology and Experimental Therapeutics. 299: 967-72. PMID 11714884 |
0.786 |
|
| 2001 |
Palian MM, Polt R. Lipo alpha-amino-beta-hydroxy acids and O-linked glycosides: building blocks for ceramyl and glycosphingoyl peptides. The Journal of Organic Chemistry. 66: 7178-83. PMID 11597248 DOI: 10.1021/Jo015844V |
0.778 |
|
| 2001 |
Palian MM, Jacobsen NE, Polt R. O-Linked glycopeptides retain helicity in water. The Journal of Peptide Research : Official Journal of the American Peptide Society. 58: 180-9. PMID 11532077 DOI: 10.1034/J.1399-3011.2001.00906.X |
0.785 |
|
| 2001 |
Mitchell SA, Pratt MR, Hruby VJ, Polt R. Solid-phase synthesis of O-linked glycopeptide analogues of enkephalin Journal of Organic Chemistry. 66: 2327-2342. PMID 11281773 DOI: 10.1021/Jo005712M |
0.399 |
|
| 2001 |
Polt R, Palian MM. Glycopeptide analgesics Drugs of the Future. 26: 561-576. DOI: 10.1358/dof.2001.026.06.668342 |
0.765 |
|
| 2000 |
Egleton RD, Mitchell SA, Huber JD, Janders J, Stropova D, Polt R, Yamamura HI, Hruby VJ, Davis TP. Improved bioavailability to the brain of glycosylated Met-enkephalin analogs. Brain Research. 881: 37-46. PMID 11033091 DOI: 10.1016/S0006-8993(00)02794-3 |
0.393 |
|
| 2000 |
Dangel BD, Polt R. Catalysis by amino acid-derived tetracoordinate complexes: enantioselective addition of dialkylzincs to aliphatic and aromatic aldehydes. Organic Letters. 2: 3003-6. PMID 10986093 DOI: 10.1021/Ol0063151 |
0.769 |
|
| 2000 |
Bilsky EJ, Egleton RD, Mitchell SA, Palian MM, Davis P, Huber JD, Jones H, Yamamura HI, Janders J, Davis TP, Porreca F, Hruby VJ, Polt R. Enkephalin glycopeptide analogues produce analgesia with reduced dependence liability. Journal of Medicinal Chemistry. 43: 2586-90. PMID 10891118 DOI: 10.1021/Jm000077Y |
0.792 |
|
| 2000 |
Kriss CT, Lou BS, Szabò LZ, Mitchell SA, Hruby VJ, Polt R. Enkephalin-based drug design: Conformational analysis of O-linked glycopeptides by NMR and molecular modeling Tetrahedron Asymmetry. 11: 9-25. DOI: 10.1016/S0957-4166(99)00544-3 |
0.381 |
|
| 1999 |
Polt R, Sames D, Chruma J. Glycosidase inhibitors: Synthesis of enantiomerically pure aza-sugars from Schiff base amino esters via tandem reduction-alkenylation and osmylation Journal of Organic Chemistry. 64: 6147-6158. DOI: 10.1021/Jo9820115 |
0.757 |
|
| 1998 |
Mitchell SA, Oates BD, Razavi H, Polt R. Glycosyltransferase inhibitors: Synthesis of D-threo-PDMP, L-threo- PDMP, and other brain glucosylceramide synthase inhibitors from D- or L- serine Journal of Organic Chemistry. 63: 8837-8842. DOI: 10.1021/Jo980951J |
0.326 |
|
| 1998 |
Razavi H, Polt R. Syntheses of iminolyxitols via tandem reduction-alkenylation of O'Donnell's Schiff bases Tetrahedron Letters. 39: 3371-3374. DOI: 10.1016/S0040-4039(98)00495-X |
0.351 |
|
| 1997 |
Dangel B, Clarke M, Haley J, Sames D, Polt R. Amino acid-derived ligands for transition metals: Catalysis via a minimalist interpretation of a metalloprotein Journal of the American Chemical Society. 119: 10865-10866. DOI: 10.1021/Ja972135J |
0.767 |
|
| 1997 |
Chruma JJ, Sames D, Polt R. General method for the synthesis of N-methyl amino acids and N-alkyl amino esters from O'Donnell's Schiff bases Tetrahedron Letters. 38: 5085-5086. DOI: 10.1016/S0040-4039(97)01132-5 |
0.762 |
|
| 1995 |
Szabó L, Ramza J, Langdon C, Polt R. Stereoselective synthesis of O-serinyl/threoninyl-2-acetamido-2-deoxy-α- or β-glycosides Carbohydrate Research. 274: 11-28. PMID 7585702 DOI: 10.1016/0008-6215(95)00016-M |
0.338 |
|
| 1995 |
Sames D, Polt R. Piperidine Triols via Enantioselective Alkylation and Osmylation of Alanine Schiff Base Esters Synlett. 1995: 552-554. DOI: 10.1055/S-1995-5282 |
0.592 |
|
| 1995 |
Sames D, Liu Y, DeYoung L, Polt R. Preparation of monosilyl acetals from esters via iBu2AlH reduction and trapping with N-(trimethylsilyl)imidazole. Addition of allyltrimethylsilane to yield homoallylic alcohols or ethers Journal of Organic Chemistry. 60: 2153-2159. DOI: 10.1021/Jo00112A039 |
0.552 |
|
| 1994 |
Polt R, Porreca F, Szabò LZ, Bilsky EJ, Davis P, Abbruscato TJ, Davis TP, Harvath R, Yamamura HI, Hruby VJ. Glycopeptide enkephalin analogues produce analgesia in mice: evidence for penetration of the blood-brain barrier. Proceedings of the National Academy of Sciences of the United States of America. 91: 7114-8. PMID 8041755 DOI: 10.1073/Pnas.91.15.7114 |
0.373 |
|
| 1994 |
Sames D, Polt R. An enantioselective synthesis of N-methylfucosamine via tandem C-C/C-O bond formation Journal of Organic Chemistry. 59: 4596-4601. DOI: 10.1021/Jo00095A039 |
0.597 |
|
| 1994 |
Hruby VJ, Misicka A, Lipkowski AW, Haaseth R, Bartosz H, Qian X, Collins N, Meyer JP, Szabo L, Polt R, Porreca F, Davis T, Yamamura HI. New opioid compounds in analgesia Regulatory Peptides. 53: S71-S72. DOI: 10.1016/0167-0115(94)90246-1 |
0.359 |
|
| 1993 |
Peterson MA, Polt R. N-diphenylmethylene-protected glycosyl acceptors. Selective β-O-glycosylation to form lactosyl-threo-ceramides Journal of Organic Chemistry. 58: 4309-4314. DOI: 10.1021/Jo00068A028 |
0.311 |
|
| 1992 |
Polt R, Peterson MA, Deyoung L. Aluminoxy acetals from α-amino esters: Chirality transfer via sequential addition of hydride and C-nucleophiles. 2-Amino alcohols and sphingosines Journal of Organic Chemistry. 57: 5469-5480. DOI: 10.1021/Jo00046A032 |
0.319 |
|
| 1992 |
Polt R, Szabo L, Treiberg J, Li Y, Hruby VJ. General methods for .alpha.- or .beta.-O-Ser/Thr glycosides and glycopeptides. Solid-phase synthesis of O-glycosyl cyclic enkephalin analogs Journal of the American Chemical Society. 114: 10249-10258. DOI: 10.1021/Ja00052A022 |
0.355 |
|
| 1992 |
Polt R, Li Y, Fernando Q, Rivera M. A synthetic method for unsymmetrical disulfides of cysteine: the bis-cysteine disulfide of meso-2,3-dimercaptosuccinic acid. Tetrahedron Letters. 33: 2961-2964. DOI: 10.1016/S0040-4039(00)79572-4 |
0.32 |
|
| 1990 |
Polt R, Peterson MA. β-Amino alcohols from amino acids: Chelation control via schiff bases Tetrahedron Letters. 31: 4985-4986. DOI: 10.1016/S0040-4039(00)97784-0 |
0.321 |
|
| 1989 |
Polt R, Seebach D. Stereoselective alkylation of glycine units in dipeptide derivatives. "Chirality transfer" via a pivalaldehyde N,N-acetal center Journal of the American Chemical Society. 111: 2622-2632. DOI: 10.1021/Ja00189A042 |
0.419 |
|
| 1988 |
Stork G, Polt RL, Li Y, Houk KN. Theoretical studies of the lithiation of enamines Journal of the American Chemical Society. 110: 8360-8367. DOI: 10.1021/Ja00233A013 |
0.443 |
|
| 1987 |
Polt R, Seebach D. Alkylation of Imidazolidinone Dipeptide Derivatives: Preparation of Enantiomerically Pure Di- and Tripeptides by ?Chirality Transfer?via a Pivalaldehyde N,N-Acetal Center. Preliminary Communication Helvetica Chimica Acta. 70: 1930-1936. DOI: 10.1002/Hlca.19870700727 |
0.438 |
|
| 1986 |
Stork G, Shiner CS, Cheng CW, Polt RL. Deprotonation of chelating enamines. Direct formation of β-lithio enamines Journal of the American Chemical Society. 108: 304-305. DOI: 10.1021/Ja00262A025 |
0.476 |
|
| 1986 |
Stork G, Shiner CS, Cheng CW, Polt RL. Deprotonation of chelating enamines. Direct formation of .beta.-lithio enamines Journal of the American Chemical Society. 108: 304-305. DOI: 10.1021/ja00262a025 |
0.402 |
|
| 1985 |
O'Donnell MJ, Bennett WD, Polt RL. Preparation of an electrophilic glycine cation equivalent and its reaction with heteroatom nucleophiles Tetrahedron Letters. 26: 695-698. DOI: 10.1016/S0040-4039(00)89111-X |
0.306 |
|
| 1985 |
O'DONNELL MJ, BENNETT WD, POLT RL, FALMAGNE J. ChemInform Abstract: Preparation of an Electrophilic Glycine Cation Equivalent and Its Reaction with Heteroatom Nucleophiles. The Synthesis of Amino Acids by Reaction of an Electrophilic Glycine Cation Equivalent with Carbon Nucleophiles. Chemischer Informationsdienst. 16. DOI: 10.1002/Chin.198525356 |
0.303 |
|
| 1984 |
Polt RL, Stork G, Carpenter GB, Williard PG. X-ray crystal structure of N-(2-lithiocyclohexenyl)-N,N′,N′-trimethyl-1,3-propanediamine: A pentavalent lithium? Journal of the American Chemical Society. 106: 4276-4277. DOI: 10.1002/Chin.198445057 |
0.605 |
|
| 1982 |
O'Donnell MJ, Polt RL. A mild and efficient route to Schiff base derivatives of amino acids Journal of Organic Chemistry. 47: 2663-2666. DOI: 10.1002/Chin.198251347 |
0.33 |
|
| Low-probability matches (unlikely to be authored by this person) |
| 1988 |
O'Donnell MJ, Bennett WD, Bruder WA, Jacobsen WN, Knuth K, LeClef B, Polt RL, Bordwell FG, Mrozack SR, Cripe TA. Acidities of glycine Schiff bases and alkylation of their conjugate bases Journal of the American Chemical Society. 110: 8520-8525. DOI: 10.1021/Ja00233A031 |
0.299 |
|
| 2018 |
Flores AJ, Bartlett MJ, Root BK, Parent KL, Heien ML, Porreca F, Polt R, Sherman SJ, Falk T. The combination of the opioid glycopeptide MMP-2200 and a NMDA receptor antagonist reduced l-DOPA-induced dyskinesia and MMP-2200 by itself reduced dopamine receptor 2-like agonist-induced dyskinesia. Neuropharmacology. 141: 260-271. PMID 30201210 DOI: 10.1016/J.Neuropharm.2018.09.005 |
0.296 |
|
| 2016 |
Kegel LL, Szabó LZ, Polt R, Pemberton JE. Alkyl melibioside and alkyl cellobioside surfactants: Effect of sugar headgroup and alkyl chain length on performance Green Chemistry. 18: 4446-4460. DOI: 10.1039/C6Gc00436A |
0.295 |
|
| 1993 |
Wijayaratne T, Collins N, Li Y, Bruck MA, Polt R. β-Alkoxy Schiff base–oxazolidine tautomerism: solid-state structure of N-diphenylmethylene-L-threonine methyl ester Acta Crystallographica Section B Structural Science. 49: 316-320. DOI: 10.1107/S0108768192007778 |
0.287 |
|
| 1991 |
Polt R, Wijayarathe T. Erythrose sesqui-acetals as electrophiles. 2-Deoxy-C-nucleosides from D-glucose Tetrahedron Letters. 32: 4831-4834. DOI: 10.1016/S0040-4039(00)93472-5 |
0.287 |
|
| 2020 |
Stevenson GW, Giuvelis D, Cormier J, Cone K, Atherton P, Krivitsky R, Warner E, St Laurent B, Dutra J, Bidlack JM, Szabò L, Polt R, Bilsky EJ. Behavioral pharmacology of the mixed-action delta-selective opioid receptor agonist BBI-11008: studies on acute, inflammatory and neuropathic pain, respiration, and drug self-administration. Psychopharmacology. PMID 31912192 DOI: 10.1007/S00213-019-05449-Z |
0.282 |
|
| 2004 |
Abeytunga DT, Glick JJ, Gibson NJ, Oland LA, Somogyi A, Wysocki VH, Polt R. Presence of unsaturated sphingomyelins and changes in their composition during the life cycle of the moth Manduca sexta. Journal of Lipid Research. 45: 1221-31. PMID 15102888 DOI: 10.1194/Jlr.M300392-Jlr200 |
0.282 |
|
| 1994 |
Szabó L, Polt R. Stereoselective synthesis of β-d-glycopyranosyl-l-serinate or -threoninate derivatives with an unusual migration Carbohydrate Research. 258: 293-297. PMID 8039183 DOI: 10.1016/0008-6215(94)84096-2 |
0.28 |
|
| 2000 |
Razavi H, Polt R. Asymmetric syntheses of (-)-8-epi-swainsonine triacetate and (+)-1,2-di-epi-swainsonine. Carbonyl addition thwarted by an unprecedented aza-pinacol rearrangement Journal of Organic Chemistry. 65: 5693-5706. PMID 10970313 DOI: 10.1021/Jo000527U |
0.278 |
|
| 2019 |
Hay M, Polt R, Heien ML, Vanderah TW, Largen-Milnes TM, Rodgers KE, Falk T, Bartlett MJ, Doyle K, Konhilas J. A Novel Angiotensin-(1-7)-glycosylated Mas Receptor Agonist for Treating Vascular Cognitive Impairment and Inflammation Related Memory Dysfunction. The Journal of Pharmacology and Experimental Therapeutics. PMID 30709867 DOI: 10.1124/Jpet.118.254854 |
0.267 |
|
| 2018 |
Hogan DE, Tian F, Malm SW, Olivares C, Palos Pacheco R, Simonich MT, Hunjan AS, Tanguay RL, Klimecki WT, Polt R, Pemberton JE, Curry JE, Maier RM. Biodegradability and toxicity of monorhamnolipid biosurfactant diastereomers. Journal of Hazardous Materials. 364: 600-607. PMID 30390580 DOI: 10.1016/J.Jhazmat.2018.10.050 |
0.264 |
|
| 2007 |
Jalbout AF, Abrell L, Adamowicz L, Polt R, Apponi AJ, Ziurys LM. Sugar synthesis from a gas-phase formose reaction. Astrobiology. 7: 433-42. PMID 17630839 DOI: 10.1089/Ast.2006.0083 |
0.255 |
|
| 1992 |
Peterson MA, Polt R. E-1-Lithio-1-Alkenes in Hydrocarbon Solvent Synthetic Communications. 22: 477-480. DOI: 10.1080/00397919208055426 |
0.254 |
|
| 2020 |
Marciniak A, Camp SM, Garcia JGN, Polt R. Docking Studies of Fingolimod and S1P Agonists. Frontiers in Pharmacology. 11: 247. PMID 32210822 DOI: 10.3389/Fphar.2020.00247 |
0.244 |
|
| 2008 |
Abeytunga DTU, Oland L, Somogyi A, Polt R. Structural studies on the neutral glycosphingolipids of Manduca sexta Bioorganic Chemistry. 36: 70-76. PMID 18023840 DOI: 10.1016/J.Bioorg.2007.10.002 |
0.243 |
|
| 2000 |
Polt R. Lipid Synthesis and Manufacture Edited by Frank D. Gunstone (Professor Emeritus, University of St. Andrews, Dundee, Scotland). CRC Press: Boca Raton. 1999. xv + 472 pp. $135.00. ISBN 0-8493-9737-5. Journal of the American Chemical Society. 122: 3985-3985. DOI: 10.1021/Ja995685L |
0.243 |
|
| 2020 |
Bartlett MJ, Mabrouk OS, Szabò L, Flores AJ, Parent KL, Bidlack JM, Heien ML, Kennedy RT, Polt R, Sherman SJ, Falk T. The Delta-Specific Opioid Glycopeptide BBI-11008: CNS Penetration and Behavioral Analysis in a Preclinical Model of Levodopa-Induced Dyskinesia. International Journal of Molecular Sciences. 22. PMID 33374986 DOI: 10.3390/ijms22010020 |
0.242 |
|
| 2006 |
Halfen DT, Apponi AJ, Woolf N, Polt R, Ziurys LM. A systematic study of glycolaldehyde in sagittarius B2(N) at 2 and 3 mm: Criteria for detecting large interstellar molecules Astrophysical Journal. 639: 237-245. DOI: 10.1086/499225 |
0.241 |
|
| 1995 |
Hruby VJ, Davis T, Polt R, Porreca F, O’Brien D, Yamamura H, Bartosz H, Szabo L, Gillespie T, Williams S, Misicka A, Lipkowski A, Qian X, Li G, Patel D, et al. DESIGN AND SYNTHESIS OF PEPTIDE LIGANDS WITH UNIQUE BIOCHEMICAL AND BIOLOGICAL PROFILES AT OPIOID RECEPTORS THAT CROSS THE BLOOD BRAIN BARRIER Analgesia. 1: 469-472. DOI: 10.3727/107156995819562961 |
0.24 |
|
| 2018 |
Marciniak A, Camp SM, Garcia JGN, Polt R. An update on sphingosine-1-phosphate receptor 1 modulators. Bioorganic & Medicinal Chemistry Letters. PMID 30409535 DOI: 10.1016/J.Bmcl.2018.10.042 |
0.235 |
|
| 2020 |
Camp SM, Marciniak A, Chiang ET, Garcia AN, Bittman R, Polt R, Perez RG, Dudek SM, Garcia JGN. Sphingosine-1-phosphate receptor-independent lung endothelial cell barrier disruption induced by FTY720 regioisomers. Pulmonary Circulation. 10. PMID 32095229 DOI: 10.1177/2045894020905521 |
0.23 |
|
| 1991 |
Szabò L, Li Y, Polt R. O-glycopeptides: a simple β-stereoselective glycosidation of serine and threonine via a favorable hydrogen bonding pattern Tetrahedron Letters. 32: 585-588. DOI: 10.1016/S0040-4039(00)74833-7 |
0.23 |
|
| 2021 |
Alabsi W, Acosta MF, Al-Obeidi FA, Hay M, Polt R, Mansour HM. Synthesis, Physicochemical Characterization, In Vitro 2D/3D Human Cell Culture, and In Vitro Aerosol Dispersion Performance of Advanced Spray Dried and Co-Spray Dried Angiotensin (1-7) Peptide and PNA5 with Trehalose as Microparticles/Nanoparticles for Targeted Respiratory Delivery as Dry Powder Inhalers. Pharmaceutics. 13. PMID 34452239 DOI: 10.3390/pharmaceutics13081278 |
0.229 |
|
| 2023 |
Szabó LZ, Tanguturi P, Goodman HJ, Sprőber S, Liu C, Al-Obeidi F, Bartlett MJ, Falk T, Kumirov VK, Heien ML, Streicher JM, Polt R. Structure-Based Design of Glycosylated Oxytocin Analogues with Improved Selectivity and Antinociceptive Activity. Acs Medicinal Chemistry Letters. 14: 163-170. PMID 36793431 DOI: 10.1021/acsmedchemlett.2c00455 |
0.226 |
|
| 2010 |
Palian MM, Polt R. ChemInform Abstract: Lipo α-Amino-β-hydroxy Acids and O-Linked Glycosides: Building Blocks for Ceramyl and Glycosphingoyl Peptides. Cheminform. 33: no-no. DOI: 10.1002/CHIN.200210207 |
0.215 |
|
| 1993 |
Weber SJ, Abbruscato TJ, Brownson EA, Lipkowski AW, Polt R, Misicka A, Haaseth RC, Bartosz H, Hruby VJ, Davis TP. Assessment of an in vitro blood-brain barrier model using several [Met5]enkephalin opioid analogs. The Journal of Pharmacology and Experimental Therapeutics. 266: 1649-55. PMID 8371162 |
0.215 |
|
| 1982 |
O'DONNELL MJ, POLT RL. ChemInform Abstract: A MILD AND EFFICIENT ROUTE TO SCHIFF BASE DERIVATIVES OF AMINO ACIDS Chemischer Informationsdienst. 13. DOI: 10.1002/chin.198251347 |
0.2 |
|
| 1982 |
O'Donnell MJ, Polt RL. A mild and efficient route to Schiff base derivatives of amino acids The Journal of Organic Chemistry. 47: 2663-2666. DOI: 10.1021/jo00134a030 |
0.197 |
|
| 2022 |
Apostol CR, Bernard K, Tanguturi P, Molnar G, Bartlett MJ, Szabò L, Liu C, Ortiz JB, Saber M, Giordano KR, Green TRF, Melvin J, Morrison HW, Madhavan L, Rowe RK, ... ... Polt R, et al. Design and Synthesis of Brain Penetrant Glycopeptide Analogues of PACAP With Neuroprotective Potential for Traumatic Brain Injury and Parkinsonism. Frontiers in Drug Discovery. 1. PMID 35237767 DOI: 10.3389/fddsv.2021.818003 |
0.195 |
|
| 1989 |
O'DONNELL MJ, BENNETT WD, BRUDER WA, JACOBSEN WN, KNUTH K, LECLEF B, POLT RL, BORDWELL FG, MROZACK SR, CRIPE TA. ChemInform Abstract: Acidities of Glycine Schiff Bases and Alkylation of Their Conjugate Bases. Cheminform. 20. DOI: 10.1002/chin.198912054 |
0.193 |
|
| 1996 |
Polt RL, Szabo L, Ramza J. [New chemical method for synthesis of O-linked glycopeptides]. PostȩPy Higieny I Medycyny DośWiadczalnej. 50: 493-503. PMID 9072765 |
0.191 |
|
| 1988 |
O'Donnell MJ, Bennett WD, Bruder WA, Jacobsen WN, Knuth K, LeClef B, Polt RL, Bordwell FG, Mrozack SR, Cripe TA. Acidities of glycine Schiff bases and alkylation of their conjugate bases Journal of the American Chemical Society. 110: 8520-8525. DOI: 10.1021/ja00233a031 |
0.19 |
|
| 2022 |
Alabsi W, Eedara BB, Encinas-Basurto D, Polt R, Mansour HM. Nose-to-Brain Delivery of Therapeutic Peptides as Nasal Aerosols. Pharmaceutics. 14. PMID 36145618 DOI: 10.3390/pharmaceutics14091870 |
0.186 |
|
| 2000 |
Polt RL. ChemInform Abstract: Benzophenone Schiff Bases of α-Amino Acid Esters as Electrophiles. Addition of Grignard Reagents and Alkyllithiums to Produce threo Amino Alcohols and Amino Polyols Cheminform. 31: no-no. DOI: 10.1002/chin.200039279 |
0.186 |
|
| 2020 |
Hogan DE, Tian F, Malm SW, Kegel LL, Szabó LZ, Hunjan AS, Pemberton JE, Klimecki WT, Polt R, Maier RM. Biodegradability and Toxicity of Cellobiosides and Melibiosides Journal of Surfactants and Detergents. 23: 715-724. DOI: 10.1002/Jsde.12421 |
0.185 |
|
| 2008 |
Polt R. Endoglycosidases: Biochemistry, Biotechnology, Application Edited by Masahiko Endo (Hirosaki University, Aomori, Japan), Sumihiro Hase (Osaka University, Osaka, Japan), Kenji Yamamoto (Kyoto University, Kyoto, Japan), and Keiichi Takagaki (Hirosaki University School of Medicine, Aomori, Japan). Kodansha Ltd: Tokyo and Springer: Berlin, Heidelberg, New York. 2006. xvi + 255 pp. $169.00. ISBN 4-06-212192-2 (Kodansha) and 3-540-34494-2 (Springer). Journal of the American Chemical Society. 130: 2878-2879. DOI: 10.1021/Ja076925X |
0.179 |
|
| 2021 |
Apostol CR, Tanguturi P, Szabò LZ, Varela D, Gilmartin T, Streicher JM, Polt R. Synthesis and In Vitro Characterization of Glycopeptide Drug Candidates Related to PACAP. Molecules (Basel, Switzerland). 26. PMID 34443519 DOI: 10.3390/molecules26164932 |
0.177 |
|
| 2022 |
Encinas-Basurto D, Konhilas JP, Polt R, Hay M, Mansour HM. Glycosylated Ang-(1-7) MasR Agonist Peptide Poly Lactic-co-Glycolic Acid (PLGA) Nanoparticles and Microparticles in Cognitive Impairment: Design, Particle Preparation, Physicochemical Characterization, and In Vitro Release. Pharmaceutics. 14. PMID 35335963 DOI: 10.3390/pharmaceutics14030587 |
0.16 |
|
| 2021 |
Eedara BB, Alabsi W, Encinas-Basurto D, Polt R, Mansour HM. Spray-Dried Inhalable Powder Formulations of Therapeutic Proteins and Peptides. Aaps Pharmscitech. 22: 185. PMID 34143327 DOI: 10.1208/s12249-021-02043-5 |
0.148 |
|
| 2020 |
Hogan DE, Tian F, Malm SW, Kegel LL, Szabo LZ, Hunjan AS, Pemberton JE, Klimecki WT, Polt R, Maier RM. Biodegradability and Toxicity of Cellobiosides and Melibiosides. Journal of Surfactants and Detergents. 23: 715-724. PMID 34305390 DOI: 10.1002/jsde.12421 |
0.142 |
|
| 1989 |
Polt R, Seebach D. Stereoselective alkylation of glycine units in dipeptide derivatives: "Chirality transfer" via a pivalaldehyde N,N-acetal center Journal of the American Chemical Society. 111: 2622-2632. |
0.138 |
|
| 2010 |
Kriss CT, Lou B, Szabo LZ, Mitchell SA, Hruby VJ, Polt R. ChemInform Abstract: Enkephalin-Based Drug Design: Conformational Analysis of O-Linked Glycopeptides by NMR and Molecular Modeling. Cheminform. 31: no-no. DOI: 10.1002/CHIN.200024186 |
0.132 |
|
| 2010 |
POLT R, SZABO L, TREIBERG J, LI Y, HRUBY VJ. ChemInform Abstract: General Methods for α- or β-O-Ser/Thr Glycosides and Glycopeptides. Solid-Phase Synthesis of O-Glycosyl Cyclic Enkephalin Analogues. Cheminform. 24: no-no. DOI: 10.1002/CHIN.199317239 |
0.131 |
|
| 1993 |
Maiorino RM, Aposhian MM, Xu ZF, Li Y, Polt RL, Aposhian HV. Determination and metabolism of dithiol chelating agents. XV. The meso-2,3-dimercaptosuccinic acid-cysteine (1:2) mixed disulfide, a major urinary metabolite of DMSA in the human, increases the urinary excretion of lead in the rat. The Journal of Pharmacology and Experimental Therapeutics. 267: 1221-6. PMID 8263783 |
0.13 |
|
| 1992 |
Polt R, Szabó L, Treiberg J, Li Y, Hruby VJ. General methods for α- Or β-O-Ser/Thr glycosides and glycopeptides. Solid-phase synthesis of O-glycosyl cyclic enkephalin analogues Journal of the American Chemical Society. 114: 10249-10258. |
0.129 |
|
| 2023 |
Hoyer-Kimura C, Hay M, Konhilas JP, Morrison HW, Methajit M, Strom J, Polt R, Salcedo V, Fricks JP, Kalya A, Pires PW. PNA5, A Novel Mas Receptor Agonist, Improves Neurovascular and Blood-Brain-Barrier Function in a Mouse Model of Vascular Cognitive Impairment and Dementia. Aging and Disease. PMID 37815905 DOI: 10.14336/AD.2023.0928 |
0.112 |
|
| 2021 |
Collins KL, Younis US, Tanyaratsrisakul S, Polt R, Hay M, Mansour HM, Ledford JG. Angiotensin-(1-7) Peptide Hormone Reduces Inflammation and Pathogen Burden during Infection in Mice. Pharmaceutics. 13. PMID 34683907 DOI: 10.3390/pharmaceutics13101614 |
0.104 |
|
| 2016 |
Jones EM, Polt R. ChemInform Abstract: CNS Active O-Linked Glycopeptides Cheminform. 47. DOI: 10.1002/chin.201603213 |
0.102 |
|
| 2023 |
Sulaiman MI, Alabsi W, Szabo L, Hay M, Polt R, Largent-Milnes TM, Vanderah TW. PNA6, a Lactosyl Analogue of Angiotensin-(1-7), Reverses Pain Induced in Murine Models of Inflammation, Chemotherapy-Induced Peripheral Neuropathy, and Metastatic Bone Disease. International Journal of Molecular Sciences. 24. PMID 37834455 DOI: 10.3390/ijms241915007 |
0.098 |
|
| 2021 |
Hoyer-Kimura C, Konhilas JP, Mansour HM, Polt R, Doyle KP, Billheimer D, Hay M. Neurofilament light: a possible prognostic biomarker for treatment of vascular contributions to cognitive impairment and dementia. Journal of Neuroinflammation. 18: 236. PMID 34654436 DOI: 10.1186/s12974-021-02281-1 |
0.079 |
|
| 2020 |
Camp SM, Marciniak A, Chiang ET, Garcia AN, Bittman R, Polt R, Perez RG, Dudek SM, Garcia JGN. Sphingosine-1-phosphate receptor-independent lung endothelial cell barrier disruption induced by FTY720 regioisomers. Pulmonary Circulation. 10. PMID 32096779 DOI: 10.1177/2045894020905521 |
0.078 |
|
| 2020 |
Alabsi W, Al-Obeidi FA, Polt R, Mansour HM. Organic Solution Advanced Spray-Dried Microparticulate/Nanoparticulate Dry Powders of Lactomorphin for Respiratory Delivery: Physicochemical Characterization, In Vitro Aerosol Dispersion, and Cellular Studies. Pharmaceutics. 13. PMID 33375607 DOI: 10.3390/pharmaceutics13010026 |
0.076 |
|
| 1989 |
STORK G, POLT RL, LI Y, HOUK KN. ChemInform Abstract: Theoretical Studies of the Lithiation of Enamines. Cheminform. 20. DOI: 10.1002/chin.198912048 |
0.056 |
|
| 2021 |
Eedara BB, Alabsi W, Encinas-Basurto D, Polt R, Ledford JG, Mansour HM. Inhalation Delivery for the Treatment and Prevention of COVID-19 Infection. Pharmaceutics. 13. PMID 34371768 DOI: 10.3390/pharmaceutics13071077 |
0.039 |
|
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