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David B. Buckley, Ph.D. - Publications

Affiliations: 
2007 Pharmacology, Toxicology & Therapeutics University of Kansas, Lawrence, KS, United States 
Area:
Toxicology, Pharmacology
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17 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Tweedie D, Kenny JR, Ramsden D, Buckley D, Dallas S, Fung C, Mohutsky M, Einolf HJ, Chen L, Dekeyser J, Fitzgerald M, Goosen T, Siu YA, Walsky R, Zhang G, et al. Recommendations for in vitro CYP3A4 mRNA data analysis for drug-drug interaction risk assessment from the IQ Induction working group Drug Metabolism and Pharmacokinetics. 34: S44. DOI: 10.1016/J.Dmpk.2018.09.159  0.309
2018 Kenny JR, Ramsden D, Buckley DB, Dallas S, Fung C, Mohutsky M, Einolf HJ, Chen L, Dekeyser JG, Fitzgerald M, Goosen TC, Siu YA, Walsky RL, Zhang G, Tweedie D, et al. Considerations from the IQ Induction Working Group in Response to Drug-Drug Interaction Guidances from Regulatory Agencies: Focus on CYP3A4 mRNA in vitro response thresholds, variability, and clinical relevance. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 29959133 DOI: 10.1124/Dmd.118.081927  0.349
2018 Kazmi F, Yerino P, McCoy C, Parkinson A, Buckley DB, Ogilvie BW. An assessment of the in vitro inhibition of cytochrome P450 enzymes (CYP), UDP-glucuronsyltransferases (UGT) and transporters by phosphodiester- or phosphorothioate-linked oligonucleotides. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 29735754 DOI: 10.1124/Dmd.118.081729  0.307
2017 Hariparsad N, Ramsden D, Palamanda J, Dekeyser JG, Fahmi OA, Kenny JR, Einolf H, Mohutsky M, Pardon M, Siu AY, Chen L, Sinz M, Jones B, Walsky R, Dallas S, ... ... Buckley D, et al. Considerations from the IQ Induction Working Group in Response to Drug-Drug Interaction Guidances from Regulatory Agencies: Focus on Down-regulation, CYP2C Induction and CYP2B6 Positive Control. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 28646080 DOI: 10.1124/Dmd.116.074567  0.309
2015 Vermeer LM, Isringhausen CD, Ogilvie BW, Buckley DB. Evaluation of Ketoconazole and its Alternative Clinical CYP3A4/5 Inhibitors as Inhibitors of Drug Transporters: The In Vitro Effects of Ketoconazole, Ritonavir, Clarithromycin and Itraconazole on 13 Clinically-Relevant Drug Transporters. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 26668209 DOI: 10.1124/Dmd.115.067744  0.336
2015 Czerwiński M, Kazmi F, Parkinson A, Buckley DB. Anti-CD28 monoclonal antibody-stimulated cytokines released from blood suppress CYP1A2, CYP2B6, and CYP3A4 in human hepatocytes in vitro. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 43: 42-52. PMID 25326287 DOI: 10.1124/Dmd.114.060186  0.337
2014 Kazmi F, Haupt LJ, Horkman JR, Smith BD, Buckley DB, Wachter EA, Singer JM. In vitro inhibition of human liver cytochrome P450 (CYP) and UDP-glucuronosyltransferase (UGT) enzymes by rose bengal: system-dependent effects on inhibitory potential. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 44: 606-14. PMID 24405273 DOI: 10.3109/00498254.2013.878814  0.334
2013 More VR, Cheng Q, Donepudi AC, Buckley DB, Lu ZJ, Cherrington NJ, Slitt AL. Alcohol cirrhosis alters nuclear receptor and drug transporter expression in human liver. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 41: 1148-55. PMID 23462698 DOI: 10.1124/Dmd.112.049676  0.407
2013 Kazmi F, Hensley T, Pope C, Funk RS, Loewen GJ, Buckley DB, Parkinson A. Lysosomal sequestration (trapping) of lipophilic amine (cationic amphiphilic) drugs in immortalized human hepatocytes (Fa2N-4 cells). Drug Metabolism and Disposition: the Biological Fate of Chemicals. 41: 897-905. PMID 23378628 DOI: 10.1124/Dmd.112.050054  0.308
2011 Ogilvie BW, Yerino P, Kazmi F, Buckley DB, Rostami-Hodjegan A, Paris BL, Toren P, Parkinson A. The proton pump inhibitor, omeprazole, but not lansoprazole or pantoprazole, is a metabolism-dependent inhibitor of CYP2C19: implications for coadministration with clopidogrel. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 39: 2020-33. PMID 21795468 DOI: 10.1124/Dmd.111.041293  0.303
2010 Parkinson A, Kazmi F, Buckley DB, Yerino P, Ogilvie BW, Paris BL. System-dependent outcomes during the evaluation of drug candidates as inhibitors of cytochrome P450 (CYP) and uridine diphosphate glucuronosyltransferase (UGT) enzymes: human hepatocytes versus liver microsomes versus recombinant enzymes. Drug Metabolism and Pharmacokinetics. 25: 16-27. PMID 20208386 DOI: 10.2133/Dmpk.25.16  0.36
2009 Li Y, Buckley D, Wang S, Klaassen CD, Zhong XB. Genetic polymorphisms in the TATA box and upstream phenobarbital-responsive enhancer module of the UGT1A1 promoter have combined effects on UDP-glucuronosyltransferase 1A1 transcription mediated by constitutive androstane receptor, pregnane X receptor, or glucocorticoid receptor in human liver. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 37: 1978-86. PMID 19541828 DOI: 10.1124/Dmd.109.027409  0.451
2009 Reisman SA, Buckley DB, Tanaka Y, Klaassen CD. CDDO-Im protects from acetaminophen hepatotoxicity through induction of Nrf2-dependent genes. Toxicology and Applied Pharmacology. 236: 109-14. PMID 19371629 DOI: 10.1016/J.Taap.2008.12.024  0.616
2009 Buckley DB, Klaassen CD. Induction of mouse UDP-glucuronosyltransferase mRNA expression in liver and intestine by activators of aryl-hydrocarbon receptor, constitutive androstane receptor, pregnane X receptor, peroxisome proliferator-activated receptor alpha, and nuclear factor erythroid 2-related factor 2. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 37: 847-56. PMID 19144771 DOI: 10.1124/Dmd.108.024190  0.539
2009 Buckley DB, Klaassen CD. Mechanism of gender-divergent UDP-glucuronosyltransferase mRNA expression in mouse liver and kidney. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 37: 834-40. PMID 19131521 DOI: 10.1124/Dmd.108.024224  0.552
2007 Cheng X, Buckley D, Klaassen CD. Regulation of hepatic bile acid transporters Ntcp and Bsep expression. Biochemical Pharmacology. 74: 1665-76. PMID 17897632 DOI: 10.1016/J.Bcp.2007.08.014  0.639
2007 Buckley DB, Klaassen CD. Tissue- and gender-specific mRNA expression of UDP-glucuronosyltransferases (UGTs) in mice. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 35: 121-7. PMID 17050650 DOI: 10.1124/Dmd.106.012070  0.551
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