| Year |
Citation |
Score |
| 2023 |
Alreja AB, Linden SB, Lee HR, Chao KL, Herzberg O, Nelson DC. Understanding the Molecular Basis for Homodimer Formation of the Pneumococcal Endolysin Cpl-1. Acs Infectious Diseases. PMID 37126660 DOI: 10.1021/acsinfecdis.2c00627 |
0.301 |
|
| 2021 |
Harhala M, Gembara K, Miernikiewicz P, Owczarek B, Kaźmierczak Z, Majewska J, Nelson DC, Dąbrowska K. DNA Dye Sytox Green in Detection of Bacteriolytic Activity: High Speed, Precision and Sensitivity Demonstrated With Endolysins. Frontiers in Microbiology. 12: 752282. PMID 34759903 DOI: 10.3389/fmicb.2021.752282 |
0.301 |
|
| 2020 |
Vander Elst N, Linden SB, Lavigne R, Meyer E, Briers Y, Nelson DC. Characterization of the Bacteriophage-Derived Endolysins PlySs2 and PlySs9 with In Vitro Lytic Activity against Bovine Mastitis . Antibiotics (Basel, Switzerland). 9. PMID 32961696 DOI: 10.3390/Antibiotics9090621 |
0.375 |
|
| 2020 |
Greenfield J, Shang X, Luo H, Zhou Y, Linden SB, Heselpoth RD, Leiman PG, Nelson DC, Herzberg O. Structure and function of bacteriophage CBA120 ORF211 (TSP2), the determinant of phage specificity towards E. coli O157:H7. Scientific Reports. 10: 15402. PMID 32958885 DOI: 10.1038/S41598-020-72373-0 |
0.361 |
|
| 2019 |
Yang H, Luo D, Etobayeva I, Li X, Gong Y, Wang S, Li Q, Xu P, Yin W, He J, Nelson DC, Wei H. Linker editing of pneumococcal lysin ClyJ conveys improved bactericidal activity. Antimicrobial Agents and Chemotherapy. PMID 31767724 DOI: 10.1128/Aac.01610-19 |
0.378 |
|
| 2019 |
Swift SM, Etobayeva IV, Reid KP, Waters JJ, Oakley BB, Donovan DM, Nelson DC. Characterization of LysBC17, a Lytic Endopeptidase from . Antibiotics (Basel, Switzerland). 8. PMID 31546935 DOI: 10.3390/Antibiotics8030155 |
0.41 |
|
| 2019 |
Shang X, Nelson DC. Contributions of Net Charge on the PlyC Endolysin CHAP Domain. Antibiotics (Basel, Switzerland). 8. PMID 31142020 DOI: 10.3390/Antibiotics8020070 |
0.35 |
|
| 2019 |
Greenfield J, Shang X, Luo H, Zhou Y, Heselpoth RD, Nelson DC, Herzberg O. Structure and tailspike glycosidase machinery of ORF212 from E. coli O157:H7 phage CBA120 (TSP3). Scientific Reports. 9: 7349. PMID 31089181 DOI: 10.1038/S41598-019-43748-9 |
0.364 |
|
| 2019 |
Schuch R, Pelzek AJ, Nelson DC, Fischetti VA. The PlyB Endolysin of Bacteriophage vB_BanS_Bcp1 Exhibits Broad-Spectrum Bactericidal Activity against Isolates. Applied and Environmental Microbiology. PMID 30850428 DOI: 10.1128/Aem.00003-19 |
0.426 |
|
| 2019 |
Yang H, Gong Y, Zhang H, Etobayeva I, Miernikiewicz P, Luo D, Li X, Zhang X, Dabrowska K, Nelson DC, He J, Wei H. ClyJ, a novel pneumococcal chimeric lysin with a CHAP catalytic domain. Antimicrobial Agents and Chemotherapy. PMID 30642930 DOI: 10.1128/Aac.02043-18 |
0.394 |
|
| 2018 |
Etobayeva I, Linden SB, Alem F, Harb L, Rizkalla L, Mosier PD, Johnson AA, Temple L, Hakami RM, Nelson DC. Discovery and Biochemical Characterization of PlyP56, PlyN74, and PlyTB40- Specific Endolysins. Viruses. 10. PMID 29883383 DOI: 10.3390/V10050276 |
0.4 |
|
| 2018 |
Zhuang X, Yang X, Altieri AS, Nelson DC, Pal U. Borrelia burgdorferi surface-located Lmp1 protein processed into region-specific polypeptides that are critical for microbial persistence. Cellular Microbiology. e12855. PMID 29749010 DOI: 10.1111/Cmi.12855 |
0.349 |
|
| 2018 |
Scholte CM, Nelson DC, Garcia M, Linden SB, Elsasser TH, Kahl S, Qu Y, Moyes KM. Short communication: Recombinant bacteriophage endolysin PlyC is nontoxic and does not alter blood neutrophil oxidative response in lactating dairy cows. Journal of Dairy Science. PMID 29729914 DOI: 10.3168/Jds.2017-13908 |
0.313 |
|
| 2016 |
Yang H, Bi Y, Shang X, Wang M, Linden SB, Li Y, Li Y, Nelson DC, Wei H. Anti-biofilm activities of a novel chimeolysin against S. mutans in physiological and cariogenic conditions. Antimicrobial Agents and Chemotherapy. PMID 27736755 DOI: 10.1128/Aac.01872-16 |
0.34 |
|
| 2016 |
Becker SC, Roach DR, Chauhan VS, Shen Y, Foster-Frey J, Powell AM, Bauchan G, Lease RA, Mohammadi H, Harty WJ, Simmons C, Schmelcher M, Camp M, Dong S, Baker JR, ... ... Nelson DC, et al. Triple-acting Lytic Enzyme Treatment of Drug-Resistant and Intracellular Staphylococcus aureus. Scientific Reports. 6: 25063. PMID 27121552 DOI: 10.1038/Srep25063 |
0.4 |
|
| 2016 |
Shen Y, Barros M, Vennemann T, Gallagher DT, Yin Y, Linden SB, Heselpoth RD, Spencer DJ, Donovan DM, Moult J, Fischetti VA, Heinrich F, Lösche M, Nelson DC. A bacteriophage endolysin that eliminates intracellular streptococci. Elife. 5. PMID 26978792 DOI: 10.7554/Elife.13152 |
0.308 |
|
| 2015 |
Yang H, Linden SB, Wang J, Yu J, Nelson DC, Wei H. A chimeolysin with extended-spectrum streptococcal host range found by an induced lysis-based rapid screening method. Scientific Reports. 5: 17257. PMID 26607832 DOI: 10.1038/Srep17257 |
0.326 |
|
| 2015 |
Yang X, Lin YP, Heselpoth RD, Buyuktanir O, Qin J, Kung F, Nelson DC, Leong JM, Pal U. Middle region of the Borrelia burgdorferi surface-located protein 1 (Lmp1) interacts with host chondroitin-6-sulfate and independently facilitates infection. Cellular Microbiology. PMID 26247174 DOI: 10.1111/Cmi.12487 |
0.352 |
|
| 2015 |
Heselpoth RD, Yin Y, Moult J, Nelson DC. Increasing the stability of the bacteriophage endolysin PlyC using rationale-based FoldX computational modeling. Protein Engineering, Design & Selection : Peds. 28: 85-92. PMID 25740429 DOI: 10.1093/Protein/Gzv004 |
0.321 |
|
| 2015 |
Schmelcher M, Shen Y, Nelson DC, Eugster MR, Eichenseher F, Hanke DC, Loessner MJ, Dong S, Pritchard DG, Lee JC, Becker SC, Foster-Frey J, Donovan DM. Evolutionarily distinct bacteriophage endolysins featuring conserved peptidoglycan cleavage sites protect mice from MRSA infection. The Journal of Antimicrobial Chemotherapy. 70: 1453-65. PMID 25630640 DOI: 10.1093/Jac/Dku552 |
0.378 |
|
| 2015 |
Heselpoth RD, Owens JM, Nelson DC. Quantitative analysis of the thermal stability of the gamma phage endolysin PlyG: a biophysical and kinetic approach to assaying therapeutic potential. Virology. 477: 125-32. PMID 25432575 DOI: 10.1016/J.Virol.2014.11.003 |
0.309 |
|
| 2015 |
Linden SB, Zhang H, Heselpoth RD, Shen Y, Schmelcher M, Eichenseher F, Nelson DC. Biochemical and biophysical characterization of PlyGRCS, a bacteriophage endolysin active against methicillin-resistant Staphylococcus aureus. Applied Microbiology and Biotechnology. 99: 741-52. PMID 25038926 DOI: 10.1007/S00253-014-5930-1 |
0.438 |
|
| 2014 |
Swift SM, Hudgens JW, Heselpoth RD, Bales PM, Nelson DC. Characterization of AlgMsp, an alginate lyase from Microbulbifer sp. 6532A. Plos One. 9: e112939. PMID 25409178 DOI: 10.1371/Journal.Pone.0112939 |
0.345 |
|
| 2014 |
Swift SM, Nelson DC. Complete Genome Sequence of Staphylococcus aureus Phage GRCS. Genome Announcements. 2. PMID 24723702 DOI: 10.1128/Genomea.00209-14 |
0.302 |
|
| 2014 |
Chen C, Bales P, Greenfield J, Heselpoth RD, Nelson DC, Herzberg O. Crystal structure of ORF210 from E. coli O157:H1 phage CBA120 (TSP1), a putative tailspike protein. Plos One. 9: e93156. PMID 24671238 DOI: 10.1371/Journal.Pone.0093156 |
0.361 |
|
| 2013 |
Wang M, Shen Y, Turko IV, Nelson DC, Li S. Determining carbapenemase activity with 18O labeling and targeted mass spectrometry. Analytical Chemistry. 85: 11014-9. PMID 24131330 DOI: 10.1021/Ac402627K |
0.359 |
|
| 2013 |
Bales PM, Renke EM, May SL, Shen Y, Nelson DC. Purification and Characterization of Biofilm-Associated EPS Exopolysaccharides from ESKAPE Organisms and Other Pathogens. Plos One. 8: e67950. PMID 23805330 DOI: 10.1371/Journal.Pone.0067950 |
0.327 |
|
| 2013 |
Shen Y, Köller T, Kreikemeyer B, Nelson DC. Rapid degradation of Streptococcus pyogenes biofilms by PlyC, a bacteriophage-encoded endolysin. The Journal of Antimicrobial Chemotherapy. 68: 1818-24. PMID 23557924 DOI: 10.1093/Jac/Dkt104 |
0.317 |
|
| 2012 |
Heselpoth RD, Nelson DC. A new screening method for the directed evolution of thermostable bacteriolytic enzymes Journal of Visualized Experiments : Jove. PMID 23169108 DOI: 10.3791/4216 |
0.39 |
|
| 2012 |
McGowan S, Buckle AM, Mitchell MS, Hoopes JT, Gallagher DT, Heselpoth RD, Shen Y, Reboul CF, Law RHP, Fischetti VA, Whisstock JC, Nelson DC. X-ray crystal structure of the streptococcal specific phage lysin PlyC Proceedings of the National Academy of Sciences of the United States of America. 109: 12752-12757. PMID 22807482 DOI: 10.1073/Pnas.1208424109 |
0.387 |
|
| 2012 |
Nelson DC, Schmelcher M, Rodriguez-Rubio L, Klumpp J, Pritchard DG, Dong S, Donovan DM. Endolysins as antimicrobials. Advances in Virus Research. 83: 299-365. PMID 22748813 DOI: 10.1016/B978-0-12-394438-2.00007-4 |
0.438 |
|
| 2011 |
Nelson DC, Garbe J, Collin M. Cysteine proteinase SpeB from Streptococcus pyogenes-A potent modifier of immunologically important host and bacterial proteins Biological Chemistry. 392: 1077-1088. PMID 22050223 DOI: 10.1515/Bc.2011.208 |
0.399 |
|
| 2010 |
Mitchell GJ, Nelson DC, Weitz JS. Quantifying enzymatic lysis: estimating the combined effects of chemistry, physiology and physics. Physical Biology. 7: 046002. PMID 20921589 DOI: 10.1088/1478-3975/7/4/046002 |
0.367 |
|
| 2009 |
Hoopes JT, Stark CJ, Kim HA, Sussman DJ, Donovan DM, Nelson DC. Use of a bacteriophage lysin, PlyC, as an enzyme disinfectant against Streptococcus equi. Applied and Environmental Microbiology. 75: 1388-94. PMID 19139235 DOI: 10.1128/Aem.02195-08 |
0.377 |
|
| 2009 |
Schuch R, Fischetti VA, Nelson DC. A genetic screen to identify bacteriophage lysins Methods in Molecular Biology (Clifton, N.J.). 502: 307-319. PMID 19082564 DOI: 10.1007/978-1-60327-565-1_18 |
0.376 |
|
| 2008 |
Johnson BT, Shaw LN, Nelson DC, Mayo JA. Extracellular proteolytic activities expressed by Bacillus pumilus isolated from endodontic and periodontal lesions. Journal of Medical Microbiology. 57: 643-51. PMID 18436599 DOI: 10.1099/Jmm.0.47754-0 |
0.352 |
|
| 2008 |
Celia LK, Nelson D, Kerr DE. Characterization of a bacteriophage lysin (Ply700) from Streptococcus uberis. Veterinary Microbiology. 130: 107-117. PMID 18242012 DOI: 10.1016/J.Vetmic.2007.12.004 |
0.405 |
|
| 2008 |
Köller T, Nelson D, Nakata M, Kreutzer M, Fischetti VA, Glocker MO, Podbielski A, Kreikemeyer B. PlyC, a novel bacteriophage lysin for compartment-dependent proteomics of group A streptococci. Proteomics. 8: 140-148. PMID 18095374 DOI: 10.1002/Pmic.200700001 |
0.357 |
|
| 2007 |
Porter CJ, Schuch R, Pelzek AJ, Buckle AM, McGowan S, Wilce MC, Rossjohn J, Russell R, Nelson D, Fischetti VA, Whisstock JC. The 1.6 A crystal structure of the catalytic domain of PlyB, a bacteriophage lysin active against Bacillus anthracis. Journal of Molecular Biology. 366: 540-50. PMID 17182056 DOI: 10.1016/J.Jmb.2006.11.056 |
0.374 |
|
| 2006 |
Fischetti VA, Nelson D, Schuch R. Reinventing phage therapy: are the parts greater than the sum? Nature Biotechnology. 24: 1508-1511. PMID 17160051 DOI: 10.1038/Nbt1206-1508 |
0.31 |
|
| 2006 |
Nelson D, Schuch R, Chahales P, Zhu S, Fischetti VA. PlyC: a multimeric bacteriophage lysin. Proceedings of the National Academy of Sciences of the United States of America. 103: 10765-70. PMID 16818874 DOI: 10.1073/Pnas.0604521103 |
0.422 |
|
| 2006 |
Yoong P, Schuch R, Nelson D, Fischetti VA. PlyPH, a Bacteriolytic Enzyme with a Broad pH Range of Activity and Lytic Action against Bacillus anthracis Journal of Bacteriology. 188: 2711-2714. PMID 16547060 DOI: 10.1128/Jb.188.7.2711-2714.2006 |
0.349 |
|
| 2005 |
Cheng Q, Nelson D, Zhu S, Fischetti VA. Removal of group B streptococci colonizing the vagina and oropharynx of mice with a bacteriophage lytic enzyme. Antimicrobial Agents and Chemotherapy. 49: 111-7. PMID 15616283 DOI: 10.1128/Aac.49.1.111-117.2005 |
0.418 |
|
| 2004 |
Yoong P, Schuch R, Nelson D, Fischetti VA. Identification of a Broadly Active Phage Lytic Enzyme with Lethal Activity against Antibiotic-Resistant Enterococcus faecalis and Enterococcus faecium Journal of Bacteriology. 186: 4808-4812. PMID 15231813 DOI: 10.1128/Jb.186.14.4808-4812.2004 |
0.384 |
|
| 2003 |
Nelson D, Schuch R, Zhu S, Tscherne DM, Fischetti VA. Genomic sequence of C1, the first streptococcal phage. Journal of Bacteriology. 185: 3325-32. PMID 12754230 DOI: 10.1128/Jb.185.11.3325-3332.2003 |
0.334 |
|
| 2002 |
Schuch R, Nelson D, Fischetti VA. A bacteriolytic agent that detects and kills Bacillus anthracis. Nature. 418: 884-889. PMID 12192412 DOI: 10.1038/Nature01026 |
0.317 |
|
| 2002 |
Goldstein JM, Nelson D, Kordula T, Mayo JA, Travis J. Extracellular arginine aminopeptidase from Streptococcus gordonii FSS2. Infection and Immunity. 70: 836-43. PMID 11796618 DOI: 10.1128/Iai.70.2.836-843.2002 |
0.376 |
|
| 2001 |
Loeffler JM, Nelson D, Fischetti VA. Rapid Killing of Streptococcus pneumoniae with a Bacteriophage Cell Wall Hydrolase Science. 294: 2170-2172. PMID 11739958 DOI: 10.1126/Science.1066869 |
0.374 |
|
| 2001 |
Nelson D, Goldstein JM, Boatright K, Harty DW, Cook SL, Hickman PJ, Potempa J, Travis J, Mayo JA. pH-regulated secretion of a glyceraldehyde-3-phosphate dehydrogenase from Streptococcus gordonii FSS2: purification, characterization, and cloning of the gene encoding this enzyme. Journal of Dental Research. 80: 371-7. PMID 11269731 DOI: 10.1177/00220345010800011301 |
0.323 |
|
| 2001 |
Nelson D, Loomis L, Fischetti VA. Prevention and elimination of upper respiratory colonization of mice by group A streptococci by using a bacteriophage lytic enzyme Proceedings of the National Academy of Sciences of the United States of America. 98: 4107-4112. PMID 11259652 DOI: 10.1073/Pnas.061038398 |
0.378 |
|
| 2000 |
Banbula A, Bugno M, Goldstein J, Yen J, Nelson D, Travis J, Potempa J. Emerging family of proline-specific peptidases of Porphyromonas gingivalis: purification and characterization of serine dipeptidyl peptidase, a structural and functional homologue of mammalian prolyl dipeptidyl peptidase IV. Infection and Immunity. 68: 1176-82. PMID 10678923 DOI: 10.1128/Iai.68.3.1176-1182.2000 |
0.349 |
|
| 1999 |
Nelson D, Potempa J, Kordula T, Travis J. Purification and characterization of a novel cysteine proteinase (periodontain) from Porphyromonas gingivalis. Evidence for a role in the inactivation of human alpha1-proteinase inhibitor. The Journal of Biological Chemistry. 274: 12245-51. PMID 10212191 DOI: 10.1074/Jbc.274.18.12245 |
0.326 |
|
| 1999 |
Banbula A, Mak P, Bugno M, Silberring J, Dubin A, Nelson D, Travis J, Potempa J. Prolyl tripeptidyl peptidase from Porphyromonas gingivalis. A novel enzyme with possible pathological implications for the development of periodontitis. The Journal of Biological Chemistry. 274: 9246-52. PMID 10092598 DOI: 10.1074/Jbc.274.14.9246 |
0.394 |
|
| 1998 |
Potempa J, Mikolajczyk-Pawlinska J, Brassell D, Nelson D, Thøgersen IB, Enghild JJ, Travis J. Comparative properties of two cysteine proteinases (gingipains R), the products of two related but individual genes of Porphyromonas gingivalis. The Journal of Biological Chemistry. 273: 21648-57. PMID 9705298 DOI: 10.1074/Jbc.273.34.21648 |
0.344 |
|
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