Douglas I. Lin, Ph.D. - Publications

Affiliations: 
2007 University of Pennsylvania, Philadelphia, PA, United States 
Area:
Cell Biology, Molecular Biology, Oncology

56 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Posada JM, Yakirevich E, Kamat AM, Sood A, Jacob JM, Bratslavsky G, Grivas P, Spiess PE, Li R, Necchi A, Mega AE, Golijanin DJ, Pavlick D, Huang RSP, Lin D, et al. Characterizing the Genomic Landscape of the Micropapillary Subtype of Urothelial Carcinoma of the Bladder Harboring Activating Extracellular Mutations of ERBB2. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 100424. PMID 38219954 DOI: 10.1016/j.modpat.2024.100424  0.302
2020 Lin DI, Killian JK, Venstrom JM, Ramkissoon SH, Ross JS, Elvin JA. Recurrent urothelial carcinoma-like FGFR3 genomic alterations in malignant Brenner tumors of the ovary. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. PMID 33077920 DOI: 10.1038/s41379-020-00699-1  0.32
2020 Huang RSP, Li X, Haberberger J, Sokol E, Severson E, Duncan DL, Hemmerich A, Edgerly C, Ferguson NL, Williams E, Elvin J, Vergilio JA, Killian JK, Lin D, Hiemenz M, et al. Biomarkers in Breast Cancer: An Integrated Analysis of Comprehensive Genomic Profiling and PD-L1 Immunohistochemistry Biomarkers in 312 Patients with Breast Cancer. The Oncologist. PMID 32869930 DOI: 10.1634/Theoncologist.2020-0449  0.305
2020 Saglam O, Lin DI, Steele CB, Killian JK, Wenham RM. A sporadic gastric-type endocervical adenocarcinoma with endometrial involvement and bilateral ovarian metastasis, a case report. Gynecologic Oncology Reports. 32: 100572. PMID 32346591 DOI: 10.1016/J.Gore.2020.100572  0.323
2020 Lin DI, Hemmerich A, Edgerly C, Duncan D, Severson EA, Huang RSP, Ramkissoon SH, Connor YD, Shea M, Hecht JL, Ali SM, Vergilio JA, Ross JS, Elvin JA. Genomic profiling of BCOR-rearranged uterine sarcomas reveals novel gene fusion partners, frequent CDK4 amplification and CDKN2A loss. Gynecologic Oncology. PMID 32156473 DOI: 10.1016/J.Ygyno.2020.02.024  0.343
2020 Madison RW, Gupta SV, Elamin YY, Lin DI, Pal SK, Necchi A, Miller VA, Ross JS, Chung JH, Alexander BM, Schrock AB, Heymach JV, Reddy P, Ali SM. Urothelial Cancer Harbors EGFR and HER2 Amplifications and Exon 20 Insertions. Bju International. PMID 31985116 DOI: 10.1111/Bju.15006  0.353
2020 Bratslavsky G, Necchi A, Grivas P, Shapiro O, Jacob J, Elvin JA, Vergilio J, Killian K, Lin DI, Williams E, Ramkissoon SH, Severson EA, Hemmerich A, Schrock AB, Chung J, et al. Metastatic renal cell carcinoma (mRCC) in young patients: A comprehensive genomic profiling (CGP) study. Journal of Clinical Oncology. 38: 727-727. DOI: 10.1200/Jco.2020.38.6_Suppl.727  0.344
2020 Yakirevich E, Perrino C, Necchi A, Grivas P, Bratslavsky G, Shapiro O, Jacob J, Sokol E, Vergilio J, Killian K, Lin DI, Ramkissoon SH, Severson EA, Chung J, Alexander BM, et al. NF2 mutation-driven renal cell carcinomas (RCC): A comprehensive genomic profiling (CGP) study. Journal of Clinical Oncology. 38: 726-726. DOI: 10.1200/Jco.2020.38.6_Suppl.726  0.372
2020 Jacob J, Shapiro O, Necchi A, Grivas P, Sokol E, Vergilio J, Killian K, Lin DI, Williams E, Ramkissoon SH, Severson EA, Hemmerich A, Chung J, Alexander BM, McGregor K, et al. Comprehensive genomic profiling (CGP) of histologic subtypes of urethral carcinomas (UrthCa). Journal of Clinical Oncology. 38: 5087-5087. DOI: 10.1200/Jco.2020.38.6_Suppl.426  0.348
2020 Necchi A, Grivas P, Bratslavsky G, Shapiro O, Jacob J, Sokol E, Vergilio J, Killian K, Lin DI, Ramkissoon SH, Severson EA, Hemmerich A, Chung J, Alexander BM, Reddy P, et al. Comprehensive genomic profiling (CGP) in post-systemic treatment (Post) metastatic sites (MET) and pretreatment (Pre) primary tumors (PT) of metastatic prostate cancer (mPC). Journal of Clinical Oncology. 38: 175-175. DOI: 10.1200/Jco.2020.38.6_Suppl.175  0.305
2020 Ross JS, Sokol E, Vergilio J, Killian K, Lin DI, Williams E, Danziger N, Ramkissoon SH, Severson EA, Hemmerich A, Edgerly CI, Huang R, Ali SM, Madison R, Alexander BM, et al. Primary versus metastatic intrahepatic cholangiocarcinoma: A comparative comprehensive genomic profiling (CGP) study. Journal of Clinical Oncology. 38: 578-578. DOI: 10.1200/Jco.2020.38.4_Suppl.578  0.356
2020 Necchi A, Grivas P, Bratslavsky G, Shapiro O, Jacob JM, Sokol E, Killian JK, Lin DI, Ramkissoon SH, Severson EA, Huang R, Alexander BM, Venstrom J, Reddy VP, McGregor K, et al. Contrasting genomic profiles in post-systemic treatment metastatic sites (MET), pretreatment primary tumors (PT), and liquid biopsies (LB) of clinically advanced prostate cancer (PC). Journal of Clinical Oncology. 38: 5534-5534. DOI: 10.1200/Jco.2020.38.15_Suppl.5534  0.349
2020 Ross JS, Sokol E, Pavlick D, Vergilio J, Killian JK, Lin DI, Williams EA, Danziger N, Ramkissoon SH, Severson EA, Hemmerich A, Edgerly CI, Huang R, Madison R, Schrock AB, et al. Primary tumor (p-bx) versus metastatic tumor (m-bx) tissue versus liquid biopsy (lb) in intrahepatic cholangiocarcinoma (IHCC): A comparative comprehensive genomic profiling (CGP) study. Journal of Clinical Oncology. 38: 4579-4579. DOI: 10.1200/Jco.2020.38.15_Suppl.4579  0.357
2020 Killian JK, Wright C, Chan L, Danziger N, Elvin JA, Vergilio J, Lin DI, Williams EA, Ramkissoon SH, Severson EA, Hemmerich A, Duncan D, Edgerly CI, Tse JY, McGregor K, et al. Increased tumor purity and improved biomarker detection using precision needle punch enrichment of pathology specimen paraffin blocks: Method validation and implementation in a prospective clinical trial. Journal of Clinical Oncology. 38: 3622-3622. DOI: 10.1200/Jco.2020.38.15_Suppl.3622  0.313
2020 Sokol E, Danziger N, Pavlick D, Elvin JA, Vergilio J, Killian JK, Lin DI, Ramkissoon SH, Severson EA, Hemmerich A, Duncan D, Edgerly CI, Huang R, Chung J, Reddy VP, et al. Clinically aggressive malignancies associated with STK11 germline mutations (STK11GCa): A comprehensive genomic profiling (CGP) study. Journal of Clinical Oncology. 38: 3558-3558. DOI: 10.1200/Jco.2020.38.15_Suppl.3558  0.341
2020 Killian JK, Yang XR, Danziger N, Elvin JA, Vergilio J, Lin DI, Williams EA, Ramkissoon SH, Severson EA, Hemmerich A, Duncan D, Edgerly CI, Huang R, Hiemenz M, Reddy VP, et al. Differential genomic landscape of clinically advanced/metastatic chordomas (mChor) based on primary tumor site. Journal of Clinical Oncology. 38: 11521-11521. DOI: 10.1200/Jco.2020.38.15_Suppl.11521  0.347
2020 McGregor K, Sokol E, Danziger N, Pavlick D, Elvin JA, Vergilio J, Killian JK, Lin DI, Williams EA, Ramkissoon SH, Severson EA, Hemmerich A, Duncan D, Huang R, Chung J, et al. Acquired RB1 mutations in estrogen receptor-positive (ER+) clinically advanced and metastatic breast cancer (MBC). Journal of Clinical Oncology. 38: 1053-1053. DOI: 10.1200/Jco.2020.38.15_Suppl.1053  0.352
2020 Williams EA, Sokol ES, Pavlick DC, Shah N, Elvin JA, Vergilio J, Killian JK, Ngo N, Lin D, Miller VA, Ross JS. Abstract P4-06-07:PIK3CA-mutant breast phyllodes tumors show a uniformly aggressive histology and significant mutual exclusivity withMED12mutation Cancer Research. DOI: 10.1158/1538-7445.Sabcs19-P4-06-07  0.31
2019 Connor YD, Miao D, Lin DI, Hayne C, Howitt BE, Dalrymple JL, DeLeonardis KR, Hacker MR, Esselen KM, Shea M. Germline mutations of SMARCA4 in small cell carcinoma of the ovary, hypercalcemic type and in SMARCA4-deficient undifferentiated uterine sarcoma: Clinical features of a single family and comparison of large cohorts. Gynecologic Oncology. PMID 31954538 DOI: 10.1016/J.Ygyno.2019.10.031  0.365
2019 Hecht JL, Lin DI, Garrett L. Endometrioid Tubal Intraepithelial Neoplasia (E-TIN) of the Fallopian Tube: A Case Series. International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists. PMID 31855954 DOI: 10.1097/Pgp.0000000000000650  0.332
2019 Tian K, Rubadue CA, Lin DI, Veta M, Pyle ME, Irshad H, Heng YJ. Automated clear cell renal carcinoma grade classification with prognostic significance. Plos One. 14: e0222641. PMID 31581201 DOI: 10.1371/Journal.Pone.0222641  0.305
2019 Lin DI, Allen JM, Hecht JL, Killian JK, Ngo NT, Edgerly C, Severson EA, Ali SM, Erlich RL, Ramkissoon SH, Vergilio JA, Ross JS, Elvin JA. SMARCA4 inactivation defines a subset of undifferentiated uterine sarcomas with rhabdoid and small cell features and germline mutation association. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. PMID 31190001 DOI: 10.1038/S41379-019-0303-Z  0.406
2019 Suster D, Ronen S, Peterson JF, Mackinnon AC, Hes O, Suster S, Lin DI. MDM2 amplification and immunohistochemical expression in sarcomatoid renal cell carcinoma. Human Pathology. PMID 30825458 DOI: 10.1016/J.Humpath.2019.02.004  0.342
2019 Tse J, Elvin JA, Vergilio J, Killian JK, Ngo N, Lin DI, Ramkissoon S, Severson EA, Hemmerich A, Pavlick D, Ali SM, Schrock AB, Chung J, Reddy P, McGregor K, et al. Extra-mammary Paget’s disease (EMPD) of the skin: A comprehensive genomic profiling (CGP) study. Journal of Clinical Oncology. 37: 9591-9591. DOI: 10.1200/Jco.2019.37.15_Suppl.9591  0.375
2019 Jacob J, Bratslavsky G, Shapiro O, Liu N, Elvin JA, Vergilio J, Killian JK, Ngo N, Lin DI, Ramkissoon S, Severson EA, Ali SM, Chung J, Schrock AB, Reddy P, et al. Metastatic penile (mPSCC), uterine cervical (mCSCC), and skin (mSSCC) squamous cell carcinomas: A comparative genomic profiling (CGP) study. Journal of Clinical Oncology. 37: 4585-4585. DOI: 10.1200/Jco.2019.37.15_Suppl.4585  0.345
2019 Madison R, Sokol E, Schrock AB, Johnson A, Pavlick D, Elvin JA, Vergilio J, Ngo N, Killian JK, Lin DI, Ramkissoon S, Severson EA, Hemmerich A, Duncan D, Ali SM, et al. FGFR2: A pan-genomic target. Journal of Clinical Oncology. 37: 3099-3099. DOI: 10.1200/Jco.2019.37.15_Suppl.3099  0.333
2019 Ross JS, Sokol E, Albacker LA, Frampton GM, Pavlick D, Elvin JA, Vergilio J, Killian JK, Ngo N, Lin DI, Ramkissoon S, Severson EA, Ali SM, Schrock AB, Chung J, et al. Immunotherapy predictive biomarkers in metastatic breast cancer (MBC). Journal of Clinical Oncology. 37: 1023-1023. DOI: 10.1200/Jco.2019.37.15_Suppl.1023  0.314
2019 Killian JK, Pavlick DC, Sokol ES, Montesion M, Jin DX, Kaplan B, Lin D, Vergilio J-, Elvin JA, Ngo N, Severson E, Ramkissoon S, Duncan D, Edgerly C, Hemmerich A, et al. Driving solo? Investigation into collaborating mutations in SDH-deficient neoplasia Annals of Oncology. 30. DOI: 10.1093/Annonc/Mdz269.056  0.388
2019 Graziano SL, Lin D, Elvin JA, Vergilio J-, Killian JK, Ngo N, Ramkissoon S, Severson E, Hemmerich A, Duncan D, Edgerly C, Ali SM, Schrock AB, Chung J, Sokol ES, et al. SMARCA4 deficient non-small cell lung cancer (NSCLC): A comprehensive genomic profiling (CGP) study Annals of Oncology. 30. DOI: 10.1093/Annonc/Mdz260.105  0.385
2019 Ou SI, Sokol ES, Trabucco SE, Jin DX, Frampton GM, Graziano SL, Elvin JA, Vergilio J-, Killian JK, Ngo N, Lin D, Ramkissoon S, Severson E, Ali SM, Schrock AB, et al. NTRK1-3 genomic fusions in non-small cell lung cancer (NSCLC) determined by comprehensive genomic profiling Annals of Oncology. 30. DOI: 10.1093/Annonc/Mdz260.071  0.372
2019 Bratslavsky G, Sokol ES, Necchi A, Shapiro O, Jacob J, Liu N, Elvin JA, Vergilio J-, Killian JK, Ngo N, Lin D, Ramkissoon S, Severson E, Ali SM, Schrock AB, et al. Malignant non-adrenal paraganglioma (mPara) and adrenal pheochromocytoma (mPheo) a comparative comprehensive genomic profiling (CGP) study Annals of Oncology. 30. DOI: 10.1093/Annonc/Mdz245  0.365
2019 Albanell J, Casadevall D, Sokol ES, Albacker LA, Elvin JA, Vergilio J-, Killian JK, Ngo N, Lin D, Ramkissoon S, Severson E, Ali SM, Schrock AB, Chung J, Reddy P, et al. PIK3CA alterations in metastatic breast cancer (mBC) Annals of Oncology. 30. DOI: 10.1093/Annonc/Mdz242.001  0.31
2019 Ngo N, Elvin J, Vergilio J, Killian J, Lin D, Ross J. P1.14-46 Genomic Profiling of Large Cell Neuroendocrine Carcinomas of Lung: A Path Towards Individualized Treatment Options Journal of Thoracic Oncology. 14. DOI: 10.1016/J.Jtho.2019.08.1197  0.328
2018 Juckett L, Lin DI, Madison R, Patriquin C, Frampton GM, Miller VA, Ross JS, Chung J, Schrock AB, Ali SM, Elvin JA. A pan-cancer landscape analysis reveals a subset of endometrial stromal and pediatric tumors defined by internal tandem duplications of BCOR. Annals of Oncology : Official Journal of the European Society For Medical Oncology. 29: viii591. PMID 32137572 DOI: 10.1093/Annonc/Mdy299.046  0.346
2018 Ta RM, Hecht JL, Lin DI. Discordant loss of mismatch repair proteins in advanced endometrial endometrioid carcinoma compared to paired primary uterine tumors. Gynecologic Oncology. PMID 30340772 DOI: 10.1016/J.Ygyno.2018.10.012  0.371
2018 Xu J, Lin DI. Oncogenic c-terminal cyclin D1 (CCND1) mutations are enriched in endometrioid endometrial adenocarcinomas. Plos One. 13: e0199688. PMID 29969496 DOI: 10.1371/Journal.Pone.0199688  0.438
2017 Lin DI, Chudnovsky Y, Duggan B, Zajchowski D, Greenbowe J, Ross JS, Gay LM, Ali SM, Elvin JA. Comprehensive genomic profiling reveals inactivating SMARCA4 mutations and low tumor mutational burden in small cell carcinoma of the ovary, hypercalcemic-type. Gynecologic Oncology. PMID 29102090 DOI: 10.1016/J.Ygyno.2017.09.031  0.401
2017 Labidi-Galy SI, Papp E, Hallberg D, Niknafs N, Adleff V, Noe M, Bhattacharya R, Novak M, Jones S, Phallen J, Hruban CA, Hirsch MS, Lin DI, Schwartz L, Maire CL, et al. High grade serous ovarian carcinomas originate in the fallopian tube. Nature Communications. 8: 1093. PMID 29061967 DOI: 10.1038/S41467-017-00962-1  0.385
2017 Jones DH, Lin DI. Amplification of the NSD3-BRD4-CHD8 pathway in pelvic high-grade serous carcinomas of tubo-ovarian and endometrial origin. Molecular and Clinical Oncology. 7: 301-307. PMID 28781807 DOI: 10.3892/Mco.2017.1289  0.408
2017 Pal SK, Ali SM, Yakirevich E, Geynisman DM, Karam JA, Elvin JA, Frampton GM, Huang X, Lin DI, Rosenzweig M, Lipson D, Stephens PJ, Ross JS, Miller VA, Agarwal N, et al. Characterization of Clinical Cases of Advanced Papillary Renal Cell Carcinoma via Comprehensive Genomic Profiling. European Urology. PMID 28592388 DOI: 10.1016/J.Eururo.2017.05.033  0.362
2016 Lin DI, Hecht JL. Targeted Screening With Combined Age- and Morphology-Based Criteria Enriches Detection of Lynch Syndrome in Endometrial Cancer. International Journal of Surgical Pathology. PMID 26842347 DOI: 10.1177/1066896916629782  0.32
2015 Ucar D, Lin DI. Amplification of the bromodomain-containing protein 4 gene in ovarian high-grade serous carcinoma is associated with worse prognosis and survival. Molecular and Clinical Oncology. 3: 1291-1294. PMID 26807235 DOI: 10.3892/Mco.2015.622  0.413
2015 Lin DI. Improved survival associated with somatic PIK3CA mutations in copy-number low endometrioid endometrial adenocarcinoma. Oncology Letters. 10: 2743-2748. PMID 26722235 DOI: 10.3892/Ol.2015.3702  0.374
2015 Pal SK, Choueiri TK, Wang K, Khaira D, Karam JA, Van Allen E, Palma NA, Stein MN, Johnson A, Squillace R, Elvin JA, Chmielecki J, Yelensky R, Yakirevich E, Lipson D, ... Lin DI, et al. Characterization of Clinical Cases of Collecting Duct Carcinoma of the Kidney Assessed by Comprehensive Genomic Profiling. European Urology. PMID 26149668 DOI: 10.1016/J.Eururo.2015.06.019  0.317
2015 Howitt BE, Hanamornroongruang S, Lin DI, Conner JE, Schulte S, Horowitz N, Crum CP, Meserve EE. Evidence for a dualistic model of high-grade serous carcinoma: BRCA mutation status, histology, and tubal intraepithelial carcinoma. The American Journal of Surgical Pathology. 39: 287-93. PMID 25581732 DOI: 10.1097/Pas.0000000000000369  0.337
2015 Howitt BE, Hanamornroongruang S, Lin D, Conner JE, Schulte S, Garber J, Crum CP, Meserve EE. Abstract POSTER-CTRL-1208: A dualistic model for the origin of high-grade serous carcinoma: BRCA mutation status, histology and tubal intraepithelial carcinoma Clinical Cancer Research. 21. DOI: 10.1158/1557-3265.Ovcasymp14-Poster-Ctrl-1208  0.388
2014 Winham WM, Lin D, Stone PJ, Nucci MR, Quick CM. Architectural versus nuclear atypia-defined FIGO grade 2 endometrial endometrioid adenocarcinoma (EEC): a clinicopathologic comparison of 154 cases with clinical follow-up. International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists. 33: 120-6. PMID 24487465 DOI: 10.1097/Pgp.0B013E31828Bb4Ed  0.306
2011 Nguyen PL, Lin DI, Lei J, Fiorentino M, Mueller E, Weinstein MH, Pagano M, Loda M. The impact of Skp2 overexpression on recurrence-free survival following radical prostatectomy. Urologic Oncology. 29: 302-8. PMID 19450994 DOI: 10.1016/J.Urolonc.2009.03.022  0.33
2008 Nguyen PL, Lei J, Mueller E, Signoretti S, D'Amico AV, Lin D, Pagano M, Weinstein MH, Loda M. The association between overexpression of skp2 and the risk of recurrence following prostatectomy. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 26: 11052. PMID 27947642 DOI: 10.1200/Jco.2008.26.15_Suppl.11052  0.357
2008 Barbash O, Zamfirova P, Lin DI, Chen X, Yang K, Nakagawa H, Lu F, Rustgi AK, Diehl JA. Mutations in Fbx4 inhibit dimerization of the SCF(Fbx4) ligase and contribute to cyclin D1 overexpression in human cancer. Cancer Cell. 14: 68-78. PMID 18598945 DOI: 10.1016/J.Ccr.2008.05.017  0.413
2008 Lin DI, Lessie MD, Gladden AB, Bassing CH, Wagner KU, Diehl JA. Disruption of cyclin D1 nuclear export and proteolysis accelerates mammary carcinogenesis Oncogene. 27: 1231-1242. PMID 17724472 DOI: 10.1038/Sj.Onc.1210738  0.666
2007 Aggarwal P, Lessie MD, Lin DI, Pontano L, Gladden AB, Nuskey B, Goradia A, Wasik MA, Klein-Szanto AJ, Rustgi AK, Bassing CH, Diehl JA. Nuclear accumulation of cyclin D1 during S phase inhibits Cul4-dependent Cdt1 proteolysis and triggers p53-dependent DNA rereplication. Genes & Development. 21: 2908-22. PMID 18006686 DOI: 10.1101/Gad.1586007  0.678
2007 Barbash O, Lin DI, Diehl JA. SCF Fbx4/alphaB-crystallin cyclin D1 ubiquitin ligase: a license to destroy. Cell Division. 2: 2. PMID 17224055 DOI: 10.1186/1747-1028-2-2  0.376
2006 Lin DI, Barbash O, Kumar KG, Weber JD, Harper JW, Klein-Szanto AJ, Rustgi A, Fuchs SY, Diehl JA. Phosphorylation-dependent ubiquitination of cyclin D1 by the SCF(FBX4-alphaB crystallin) complex. Molecular Cell. 24: 355-66. PMID 17081987 DOI: 10.1016/J.Molcel.2006.09.007  0.37
2006 Berger R, Lin DI, Nieto M, Sicinska E, Garraway LA, Adams H, Signoretti S, Hahn WC, Loda M. Androgen-dependent regulation of Her-2/neu in prostate cancer cells. Cancer Research. 66: 5723-8. PMID 16740710 DOI: 10.1158/0008-5472.Can-05-3928  0.326
2001 Waltregny D, Leav I, Signoretti S, Soung P, Lin D, Merk F, Adams JY, Bhattacharya N, Cirenei N, Loda M. Androgen-driven prostate epithelial cell proliferation and differentiation in vivo involve the regulation of p27. Molecular Endocrinology. 15: 765-782. PMID 11328857 DOI: 10.1210/Mend.15.5.0640  0.317
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