| Year |
Citation |
Score |
| 2020 |
Hood VL, Paterson C, Law AJ. PI3Kinase-p110δ Overexpression Impairs Dendritic Morphogenesis and Increases Dendritic Spine Density. Frontiers in Molecular Neuroscience. 13: 29. PMID 32180704 DOI: 10.3389/Fnmol.2020.00029 |
0.4 |
|
| 2020 |
Paterson C, Cumming B, Law AJ. Temporal Dynam ics of the Neuregulin-ErbB Network in the Murine Prefrontal Cortex across the Lifespan. Cerebral Cortex (New York, N.Y. : 1991). PMID 31897479 DOI: 10.1093/Cercor/Bhz312 |
0.381 |
|
| 2019 |
Howell KR, Law AJ. Neurodevelopmental concepts of schizophrenia in the genome-wide association era: AKT/mTOR signaling as a pathological mediator of genetic and environmental programming during development. Schizophrenia Research. PMID 31522868 DOI: 10.1016/J.Schres.2019.08.036 |
0.433 |
|
| 2019 |
Pacheco A, Berger R, Freedman R, Law AJ. A VNTR Regulates miR-137 Expression Through Novel Alternative Splicing and Contributes to Risk for Schizophrenia. Scientific Reports. 9: 11793. PMID 31409837 DOI: 10.1038/S41598-019-48141-0 |
0.301 |
|
| 2019 |
Hood VL, Berger R, Freedman R, Law AJ. Transcription of PIK3CD in human brain and schizophrenia: Regulation by pro inflammatory cytokines. Human Molecular Genetics. PMID 31211828 DOI: 10.1093/Hmg/Ddz144 |
0.437 |
|
| 2018 |
Deakin IH, Godlewska BR, Walker MA, Huang GJ, Schwab MH, Nave KA, Law AJ, Harrison PJ. Altered hippocampal gene expression and structure in transgenic mice overexpressing neuregulin 1 (Nrg1) type I. Translational Psychiatry. 8: 229. PMID 30348978 DOI: 10.1038/S41398-018-0288-2 |
0.525 |
|
| 2018 |
Paterson C, Law AJ. Toward Better Strategies for Understanding Disrupted Cortical Excitatory/Inhibitory Balance in Schizophrenia. Biological Psychiatry. 83: 632-634. PMID 29559094 DOI: 10.1016/J.Biopsych.2018.02.014 |
0.46 |
|
| 2017 |
Howell KR, Floyd K, Law AJ. PKBγ/AKT3 loss-of-function causes learning and memory deficits and deregulation of AKT/mTORC2 signaling: Relevance for schizophrenia. Plos One. 12: e0175993. PMID 28467426 DOI: 10.1371/Journal.Pone.0175993 |
0.44 |
|
| 2017 |
Law A. 725. Behavioral, Neurophysiological and Synaptic Impairment in a Transgenic Neuregulin1 (NRG1-IV) Murine Schizophrenia Model Biological Psychiatry. 81. DOI: 10.1016/J.Biopsych.2017.02.792 |
0.437 |
|
| 2017 |
Fregoso V, Paterson C, Law A. 515. Effects of PIK3CD Over-Expression on Neuronal Morphology: Implications for Schizophrenia Biological Psychiatry. 81. DOI: 10.1016/J.Biopsych.2017.02.1123 |
0.459 |
|
| 2016 |
Paterson C, Wang Y, Hyde TM, Weinberger DR, Kleinman JE, Law AJ. Temporal, Diagnostic, and Tissue-Specific Regulation of NRG3 Isoform Expression in Human Brain Development and Affective Disorders. The American Journal of Psychiatry. appiajp201616060721. PMID 27771971 DOI: 10.1176/Appi.Ajp.2016.16060721 |
0.501 |
|
| 2016 |
Papaleo F, Yang F, Paterson C, Palumbo S, Carr GV, Wang Y, Floyd K, Huang W, Thomas CJ, Chen J, Weinberger DR, Law AJ. Behavioral, Neurophysiological, and Synaptic Impairment in a Transgenic Neuregulin1 (NRG1-IV) Murine Schizophrenia Model. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 4859-75. PMID 27122041 DOI: 10.1523/Jneurosci.4632-15.2016 |
0.53 |
|
| 2015 |
Jenkins AK, Paterson C, Wang Y, Hyde TM, Kleinman JE, Law AJ. Neurexin 1 (NRXN1) splice isoform expression during human neocortical development and aging. Molecular Psychiatry. PMID 26216298 DOI: 10.1038/Mp.2015.107 |
0.468 |
|
| 2014 |
Paterson C, Law AJ. Transient overexposure of neuregulin 3 during early postnatal development impacts selective behaviors in adulthood. Plos One. 9: e104172. PMID 25093331 DOI: 10.1371/Journal.Pone.0104172 |
0.494 |
|
| 2014 |
Law AJ. Genetic mouse models of neuregulin 1: gene dosage effects, isoform-specific functions, and relevance to schizophrenia. Biological Psychiatry. 76: 89-90. PMID 24948382 DOI: 10.1016/J.Biopsych.2014.05.016 |
0.465 |
|
| 2014 |
Paterson C, Wang Y, Kleinman JE, Law AJ. Effects of schizophrenia risk variation in the NRG1 gene on NRG1-IV splicing during fetal and early postnatal human neocortical development. The American Journal of Psychiatry. 171: 979-89. PMID 24935406 DOI: 10.1176/Appi.Ajp.2014.13111518 |
0.522 |
|
| 2014 |
Morita Y, Callicott JH, Testa LR, Mighdoll MI, Dickinson D, Chen Q, Tao R, Lipska BK, Kolachana B, Law AJ, Ye T, Straub RE, Weinberger DR, Kleinman JE, Hyde TM. Characteristics of the cation cotransporter NKCC1 in human brain: alternate transcripts, expression in development, and potential relationships to brain function and schizophrenia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 4929-40. PMID 24695712 DOI: 10.1523/Jneurosci.1423-13.2014 |
0.501 |
|
| 2014 |
Jenkins A, Apud JA, Zhang F, Decot H, Weinberger DR, Law AJ. Identification of candidate single-nucleotide polymorphisms in NRXN1 related to antipsychotic treatment response in patients with schizophrenia. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 2170-8. PMID 24633560 DOI: 10.1038/Npp.2014.65 |
0.472 |
|
| 2014 |
Tost H, Callicott JH, Rasetti R, Vakkalanka R, Mattay VS, Weinberger DR, Law AJ. Effects of neuregulin 3 genotype on human prefrontal cortex physiology. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 1051-6. PMID 24431462 DOI: 10.1523/Jneurosci.3496-13.2014 |
0.464 |
|
| 2014 |
Gothelf D, Law AJ, Frisch A, Chen J, Zarchi O, Michaelovsky E, Ren-Patterson R, Lipska BK, Carmel M, Kolachana B, Weizman A, Weinberger DR. Biological effects of COMT haplotypes and psychosis risk in 22q11.2 deletion syndrome. Biological Psychiatry. 75: 406-13. PMID 23992923 DOI: 10.1016/J.Biopsych.2013.07.021 |
0.35 |
|
| 2014 |
Law AJ. NRG1/ErbB4 and the PI3K/AKT pathway: Novel therapeutic options for schizophrenia Schizophrenia Research. 160: e10-e11. DOI: 10.1016/J.Schres.2014.09.076 |
0.431 |
|
| 2012 |
Law AJ, Wang Y, Sei Y, O'Donnell P, Piantadosi P, Papaleo F, Straub RE, Huang W, Thomas CJ, Vakkalanka R, Besterman AD, Lipska BK, Hyde TM, Harrison PJ, Kleinman JE, et al. Neuregulin 1-ErbB4-PI3K signaling in schizophrenia and phosphoinositide 3-kinase-p110δ inhibition as a potential therapeutic strategy. Proceedings of the National Academy of Sciences of the United States of America. 109: 12165-70. PMID 22689948 DOI: 10.1073/Pnas.1206118109 |
0.602 |
|
| 2012 |
Deakin IH, Nissen W, Law AJ, Lane T, Kanso R, Schwab MH, Nave KA, Lamsa KP, Paulsen O, Bannerman DM, Harrison PJ. Transgenic overexpression of the type I isoform of neuregulin 1 affects working memory and hippocampal oscillations but not long-term potentiation. Cerebral Cortex (New York, N.Y. : 1991). 22: 1520-9. PMID 21878485 DOI: 10.1093/Cercor/Bhr223 |
0.502 |
|
| 2011 |
Marder SR, Roth B, Sullivan PF, Scolnick EM, Nestler EJ, Geyer MA, Welnberger DR, Karayiorgou M, Guidotti A, Gingrich J, Akbarian S, Buchanan RW, Lieberman JA, Conn PJ, Haggarty SJ, ... Law AJ, et al. Advancing drug discovery for schizophrenia. Annals of the New York Academy of Sciences. 1236: 30-43. PMID 22032400 DOI: 10.1111/J.1749-6632.2011.06216.X |
0.442 |
|
| 2011 |
Marenco S, Geramita M, van der Veen JW, Barnett AS, Kolachana B, Shen J, Weinberger DR, Law AJ. Genetic association of ErbB4 and human cortical GABA levels in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 11628-32. PMID 21832192 DOI: 10.1523/Jneurosci.1529-11.2011 |
0.401 |
|
| 2011 |
Hyde TM, Lipska BK, Ali T, Mathew SV, Law AJ, Metitiri OE, Straub RE, Ye T, Colantuoni C, Herman MM, Bigelow LB, Weinberger DR, Kleinman JE. Expression of GABA signaling molecules KCC2, NKCC1, and GAD1 in cortical development and schizophrenia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 11088-95. PMID 21795557 DOI: 10.1523/Jneurosci.1234-11.2011 |
0.497 |
|
| 2011 |
Kleinman JE, Law AJ, Lipska BK, Hyde TM, Ellis JK, Harrison PJ, Weinberger DR. Genetic neuropathology of schizophrenia: new approaches to an old question and new uses for postmortem human brains. Biological Psychiatry. 69: 140-5. PMID 21183009 DOI: 10.1016/J.Biopsych.2010.10.032 |
0.605 |
|
| 2010 |
Nicodemus KK, Law AJ, Radulescu E, Luna A, Kolachana B, Vakkalanka R, Rujescu D, Giegling I, Straub RE, McGee K, Gold B, Dean M, Muglia P, Callicott JH, Tan HY, et al. Biological validation of increased schizophrenia risk with NRG1, ERBB4, and AKT1 epistasis via functional neuroimaging in healthy controls. Archives of General Psychiatry. 67: 991-1001. PMID 20921115 DOI: 10.1001/Archgenpsychiatry.2010.117 |
0.458 |
|
| 2010 |
Tan W, Dean M, Law AJ. Molecular cloning and characterization of the human ErbB4 gene: identification of novel splice isoforms in the developing and adult brain. Plos One. 5: e12924. PMID 20886074 DOI: 10.1371/Journal.Pone.0012924 |
0.41 |
|
| 2010 |
Kao WT, Wang Y, Kleinman JE, Lipska BK, Hyde TM, Weinberger DR, Law AJ. Common genetic variation in Neuregulin 3 (NRG3) influences risk for schizophrenia and impacts NRG3 expression in human brain. Proceedings of the National Academy of Sciences of the United States of America. 107: 15619-24. PMID 20713722 DOI: 10.1073/Pnas.1005410107 |
0.551 |
|
| 2010 |
Arabadzisz D, Diaz-Heijtz R, Knuesel I, Weber E, Pilloud S, Dettling AC, Feldon J, Law AJ, Harrison PJ, Pryce CR. Primate early life stress leads to long-term mild hippocampal decreases in corticosteroid receptor expression. Biological Psychiatry. 67: 1106-9. PMID 20132928 DOI: 10.1016/J.Biopsych.2009.12.016 |
0.47 |
|
| 2010 |
Law A. Erbb4 And Pi3Kcd And Are Interacting Biological And Genetic Factors That Regulate Nrg1-Mediated Pi3K Signaling And Risk For Schizophrenia Schizophrenia Research. 117: 105-106. DOI: 10.1016/J.Schres.2010.02.009 |
0.416 |
|
| 2009 |
Deakin IH, Law AJ, Oliver PL, Schwab MH, Nave KA, Harrison PJ, Bannerman DM. Behavioural characterization of neuregulin 1 type I overexpressing transgenic mice. Neuroreport. 20: 1523-8. PMID 19829162 DOI: 10.1097/Wnr.0B013E328330F6E7 |
0.506 |
|
| 2009 |
Nicodemus KK, Law AJ, Luna A, Vakkalanka R, Straub RE, Kleinman JE, Weinberger DR. A 5' promoter region SNP in NRG1 is associated with schizophrenia risk and type III isoform expression. Molecular Psychiatry. 14: 741-3. PMID 19626024 DOI: 10.1038/Mp.2008.150 |
0.518 |
|
| 2009 |
Law AJ, Pei Q, Feldon J, Pryce CR, Harrison PJ. Gene expression in the anterior cingulate cortex and amygdala of adolescent marmoset monkeys following parental separations in infancy. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 12: 761-72. PMID 19102816 DOI: 10.1017/S1461145708009723 |
0.484 |
|
| 2009 |
Law AJ, Pei Q, Walker M, Gordon-Andrews H, Weickert CS, Feldon J, Pryce CR, Harrison PJ. Early parental deprivation in the marmoset monkey produces long-term changes in hippocampal expression of genes involved in synaptic plasticity and implicated in mood disorder. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 1381-94. PMID 18615010 DOI: 10.1038/Npp.2008.106 |
0.521 |
|
| 2008 |
Chong VZ, Thompson M, Beltaifa S, Webster MJ, Law AJ, Weickert CS. Elevated neuregulin-1 and ErbB4 protein in the prefrontal cortex of schizophrenic patients. Schizophrenia Research. 100: 270-80. PMID 18243664 DOI: 10.1016/J.Schres.2007.12.474 |
0.458 |
|
| 2007 |
Mathew SV, Law AJ, Lipska BK, Dávila-García MI, Zamora ED, Mitkus SN, Vakkalanka R, Straub RE, Weinberger DR, Kleinman JE, Hyde TM. Alpha7 nicotinic acetylcholine receptor mRNA expression and binding in postmortem human brain are associated with genetic variation in neuregulin 1. Human Molecular Genetics. 16: 2921-32. PMID 17884806 DOI: 10.1093/Hmg/Ddm253 |
0.44 |
|
| 2007 |
Tan W, Wang Y, Gold B, Chen J, Dean M, Harrison PJ, Weinberger DR, Law AJ. Molecular cloning of a brain-specific, developmentally regulated neuregulin 1 (NRG1) isoform and identification of a functional promoter variant associated with schizophrenia. The Journal of Biological Chemistry. 282: 24343-51. PMID 17565985 DOI: 10.1074/Jbc.M702953200 |
0.571 |
|
| 2007 |
Law AJ, Kleinman JE, Weinberger DR, Weickert CS. Disease-associated intronic variants in the ErbB4 gene are related to altered ErbB4 splice-variant expression in the brain in schizophrenia. Human Molecular Genetics. 16: 129-41. PMID 17164265 DOI: 10.1093/Hmg/Ddl449 |
0.506 |
|
| 2006 |
Law AJ, Lipska BK, Weickert CS, Hyde TM, Straub RE, Hashimoto R, Harrison PJ, Kleinman JE, Weinberger DR. Neuregulin 1 transcripts are differentially expressed in schizophrenia and regulated by 5' SNPs associated with the disease. Proceedings of the National Academy of Sciences of the United States of America. 103: 6747-52. PMID 16618933 DOI: 10.1073/Pnas.0602002103 |
0.576 |
|
| 2006 |
Harrison PJ, Law AJ. Neuregulin 1 and schizophrenia: genetics, gene expression, and neurobiology. Biological Psychiatry. 60: 132-40. PMID 16442083 DOI: 10.1016/J.Biopsych.2005.11.002 |
0.611 |
|
| 2005 |
LAW AJ, WEICKERT CS, HYDE TM, KLEINMAN JE, HARRISON PJ. Dr. Law and Colleagues Reply American Journal of Psychiatry. 162: 1389-a-1390. DOI: 10.1176/Appi.Ajp.162.7.1389-A |
0.334 |
|
| 2004 |
Law AJ, Weickert CS, Hyde TM, Kleinman JE, Harrison PJ. Reduced spinophilin but not microtubule-associated protein 2 expression in the hippocampal formation in schizophrenia and mood disorders: molecular evidence for a pathology of dendritic spines. The American Journal of Psychiatry. 161: 1848-55. PMID 15465982 DOI: 10.1176/Ajp.161.10.1848 |
0.587 |
|
| 2004 |
Law AJ, Shannon Weickert C, Hyde TM, Kleinman JE, Harrison PJ. Neuregulin-1 (NRG-1) mRNA and protein in the adult human brain. Neuroscience. 127: 125-36. PMID 15219675 DOI: 10.1016/J.Neuroscience.2004.04.026 |
0.533 |
|
| 2004 |
Law AJ, Hutchinson LJ, Burnet PW, Harrison PJ. Antipsychotics increase microtubule-associated protein 2 mRNA but not spinophilin mRNA in rat hippocampus and cortex. Journal of Neuroscience Research. 76: 376-82. PMID 15079866 DOI: 10.1002/Jnr.20092 |
0.552 |
|
| 2003 |
Law AJ, Weickert CS, Webster MJ, Herman MM, Kleinman JE, Harrison PJ. Changes in NMDA receptor subunit mRNAs and cyclophilin mRNA during development of the human hippocampus. Annals of the New York Academy of Sciences. 1003: 426-30. PMID 14684479 DOI: 10.1196/Annals.1300.043 |
0.433 |
|
| 2003 |
Harrison PJ, Law AJ, Eastwood SL. Glutamate receptors and transporters in the hippocampus in schizophrenia. Annals of the New York Academy of Sciences. 1003: 94-101. PMID 14684437 DOI: 10.1196/Annals.1300.006 |
0.582 |
|
| 2003 |
Law AJ, Harrison PJ. The distribution and morphology of prefrontal cortex pyramidal neurons identified using anti-neurofilament antibodies SMI32, N200 and FNP7. Normative data and a comparison in subjects with schizophrenia, bipolar disorder or major depression. Journal of Psychiatric Research. 37: 487-99. PMID 14563380 DOI: 10.1016/S0022-3956(03)00075-X |
0.491 |
|
| 2003 |
Law AJ, Weickert CS, Webster MJ, Herman MM, Kleinman JE, Harrison PJ. Expression of NMDA receptor NR1, NR2A and NR2B subunit mRNAs during development of the human hippocampal formation. The European Journal of Neuroscience. 18: 1197-205. PMID 12956718 DOI: 10.1046/J.1460-9568.2003.02850.X |
0.499 |
|
| 2003 |
Law A. Schizophrenia, IV: neuregulin-1 in the human brain The American Journal of Psychiatry. 160: 1392. PMID 12900297 DOI: 10.1176/Appi.Ajp.160.8.1392 |
0.472 |
|
| 2003 |
Eastwood SL, Law AJ, Everall IP, Harrison PJ. The axonal chemorepellant semaphorin 3A is increased in the cerebellum in schizophrenia and may contribute to its synaptic pathology. Molecular Psychiatry. 8: 148-55. PMID 12610647 DOI: 10.1038/Sj.Mp.4001233 |
0.603 |
|
| 2003 |
Law A, Shannon-Weickert C, Hyde T, Kleinman J, Harrison P. Does synaptic pathology in schizophrenia involve a selective dendritic spine deficit? A study of spinophilin and MAP2 gene expression in the hippocampus Schizophrenia Research. 60: 72-73. DOI: 10.1016/S0920-9964(03)80601-1 |
0.561 |
|
| 2002 |
Deakin J, Toro C, Law A. Glutamate system gene expression in schizophrenia European Psychiatry. 17: 24. DOI: 10.1016/S0924-9338(02)80111-0 |
0.389 |
|
| 2001 |
Law AJ, Deakin JF. Asymmetrical reductions of hippocampal NMDAR1 glutamate receptor mRNA in the psychoses. Neuroreport. 12: 2971-4. PMID 11588613 DOI: 10.1097/00001756-200109170-00043 |
0.485 |
|
| 2000 |
Law A, Deakin J. N-methyl-d-aspartate receptor subunit 1 in the human hippocampus: Evidence for a loss of asymmetrical gene expression in schizophrenia Schizophrenia Research. 41: 109. DOI: 10.1016/S0920-9964(00)90561-9 |
0.35 |
|
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