Roberto Ciccocioppo - Publications

Affiliations: 
University of Camerino, Italy 
Area:
ADDICTION

230 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Petrella M, Borruto AM, Curti L, Domi A, Domi E, Xu L, Barbier E, Ilari A, Heilig M, Weiss F, Mannaioni G, Masi A, Ciccocioppo R. Pharmacological blockage of NOP receptors decreases ventral tegmental area dopamine neuronal activity through GABA receptor-mediated mechanism. Neuropharmacology. 248: 109866. PMID 38364970 DOI: 10.1016/j.neuropharm.2024.109866  0.668
2023 Kallupi M, Ciccocioppo R. Cue-induced reinstatement of seeking behavior in male rats is independent from the rewarding value of the primary reinforcer: Effect of mGluR5 blockade. Neuropharmacology. 240: 109694. PMID 37659439 DOI: 10.1016/j.neuropharm.2023.109694  0.745
2023 Khom S, Borgonetti V, Vozella V, Kirson D, Rodriguez L, Gandhi P, Bianchi PC, Snyder A, Vlkolinsky R, Bajo M, Oleata CS, Ciccocioppo R, Roberto M. Glucocorticoid receptors regulate central amygdala GABAergic synapses in Marchigian-Sardinian alcohol-preferring rats. Neurobiology of Stress. 25: 100547. PMID 37547774 DOI: 10.1016/j.ynstr.2023.100547  0.612
2023 Lunerti V, Shen Q, Li H, Benvenuti F, Soverchia L, Narendran R, Weiss F, Cannella N, Ciccocioppo R. Cebranopadol, a novel long-acting opioid agonist with low abuse liability, to treat opioid use disorder: Preclinical evidence of efficacy. Biorxiv : the Preprint Server For Biology. PMID 37546836 DOI: 10.1101/2023.07.21.550008  0.604
2023 Vozella V, Cruz B, Feldman HC, Bullard R, Bianchi PC, Natividad LA, Cravatt BF, Zorrilla EP, Ciccocioppo R, Roberto M. Sexually dimorphic effects of monoacylglycerol lipase inhibitor MJN110 on stress-related behaviors and drinking in Marchigian Sardinian alcohol-preferring rats. British Journal of Pharmacology. PMID 37488777 DOI: 10.1111/bph.16197  0.529
2023 Haass-Koffler CL, Magill M, Cannella N, Brown JC, Aoun EG, Cioe PA, Sinha R, Swift RM, Ciccocioppo R, Leggio L. Mifepristone as a pharmacological intervention for stress-induced alcohol craving: A human laboratory study. Addiction Biology. 28: e13288. PMID 37369125 DOI: 10.1111/adb.13288  0.365
2023 Tollefson S, Stoughton C, Himes ML, McKinney KE, Mason S, Ciccocioppo R, Narendran R. Imaging Nociceptin Opioid Peptide Receptors in Alcohol Use Disorder With [C]NOP-1A and Positron Emission Tomography: Findings From a Second Cohort. Biological Psychiatry. PMID 36906499 DOI: 10.1016/j.biopsych.2022.12.022  0.309
2023 Haass-Koffler CL, Magill M, Cannella N, Brown JC, Aoun EG, Cioe PA, Sinha R, Swift RM, Ciccocioppo R, Leggio L. Mifepristone as a pharmacological intervention for stress-Induced alcohol craving: a translational crossover randomized trial. Medrxiv : the Preprint Server For Health Sciences. PMID 36711869 DOI: 10.1101/2023.01.02.23284122  0.385
2022 Curley DE, Vasaturo-Kolodner TR, Cannella N, Ciccocioppo R, Haass-Koffler CL. Yohimbine as a pharmacological probe for alcohol research: a systematic review of rodent and human studies. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 35760866 DOI: 10.1038/s41386-022-01363-9  0.303
2022 Pérez-Ramírez Ú, López-Madrona VJ, Pérez-Segura A, Pallarés V, Moreno A, Ciccocioppo R, Hyytiä P, Sommer WH, Moratal D, Canals S. Brain Network Allostasis after Chronic Alcohol Drinking Is Characterized by Functional Dedifferentiation and Narrowing. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 35437279 DOI: 10.1523/JNEUROSCI.0389-21.2022  0.329
2021 Ubaldi M, Cannella N, Borruto AM, Petrella M, Micioni Di Bonaventura MV, Soverchia L, Stopponi S, Weiss F, Cifani C, Ciccocioppo R. Role of Nociceptin/Orphanin FQ-NOP Receptor System in the Regulation of Stress-Related Disorders. International Journal of Molecular Sciences. 22. PMID 34884757 DOI: 10.3390/ijms222312956  0.614
2021 Domi A, Lunerti V, Petrella M, Domi E, Borruto AM, Ubaldi M, Weiss F, Ciccocioppo R. Genetic Deletion or Pharmacological Blockade of Nociceptin/Orphanin FQ Receptors in the Ventral Tegmental Area Attenuates Nicotine-Motivated Behaviour. British Journal of Pharmacology. PMID 34854073 DOI: 10.1111/bph.15762  0.636
2021 Borruto AM, Fotio Y, Stopponi S, Petrella M, De Carlo S, Domi A, Ubaldi M, Weiss F, Ciccocioppo R. NOP receptor antagonism attenuates reinstatement of alcohol-seeking through modulation of the mesolimbic circuitry in male and female alcohol-preferring rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 34285372 DOI: 10.1038/s41386-021-01096-1  0.851
2021 Fotio Y, Sasso O, Ciccocioppo R, Piomelli D. . The Journal of Pharmacology and Experimental Therapeutics. PMID 33986036 DOI: 10.1124/jpet.121.000674  0.766
2021 Benvenuti F, Cannella N, Stopponi S, Soverchia L, Ubaldi M, Lunerti V, Vozella V, Cruz B, Roberto M, Ciccocioppo R. Effect of Glucocorticoid Receptor Antagonism on Alcohol Self-Administration in Genetically-Selected Marchigian Sardinian Alcohol-Preferring and Non-Preferring Wistar Rats. International Journal of Molecular Sciences. 22. PMID 33920737 DOI: 10.3390/ijms22084184  0.613
2021 Vozella V, Cruz B, Natividad LA, Benvenuti F, Cannella N, Edwards S, Zorrilla EP, Ciccocioppo R, Roberto M. Glucocorticoid Receptor Antagonist Mifepristone Does Not Alter Innate Anxiety-Like Behavior in Genetically-Selected Marchigian Sardinian (msP) Rats. International Journal of Molecular Sciences. 22. PMID 33803557 DOI: 10.3390/ijms22063095  0.566
2021 Caputi FF, Stopponi S, Rullo L, Palmisano M, Ubaldi M, Candeletti S, Ciccocioppo R, Romualdi P. Dysregulation of Nociceptin/Orphanin FQ and Dynorphin Systems in the Extended Amygdala of Alcohol Preferring Marchigian Sardinian (msP) Rats. International Journal of Molecular Sciences. 22. PMID 33671048 DOI: 10.3390/ijms22052448  0.464
2021 Borruto AM, Stopponi S, Li H, Weiss F, Roberto M, Ciccocioppo R. Genetically Selected Alcohol-Preferring msP Rats to Study Alcohol Use Disorder: Anything Lost in Translation? Neuropharmacology. 108446. PMID 33476639 DOI: 10.1016/j.neuropharm.2020.108446  0.741
2021 Stopponi S, Fotio Y, Cifani C, Li H, Haass-Koffler CL, Cannella N, Demopulos G, Gaitanaris G, Ciccocioppo R. Andrographis paniculata and Its Main Bioactive Ingredient Andrographolide Decrease Alcohol Drinking and Seeking in Rats Through Activation of Nuclear PPARγ Pathway. Alcohol and Alcoholism (Oxford, Oxfordshire). PMID 33401299 DOI: 10.1093/alcalc/agaa136  0.785
2020 Natividad LA, Steinman MQ, McGinn MA, Sureshchandra S, Kerr TM, Ciccocioppo R, Messaoudi I, Edwards S, Roberto M. Impaired hypothalamic feedback dysregulates brain glucocorticoid signaling in genetically-selected Marchigian Sardinian alcohol-preferring rats. Addiction Biology. e12978. PMID 33142367 DOI: 10.1111/adb.12978  0.568
2020 Fotio Y, Ciccocioppo R, Piomelli D. N-acylethanolamine acid amidase (NAAA) inhibition decreases the motivation for alcohol in Marchigian Sardinian alcohol-preferring rats. Psychopharmacology. PMID 33037452 DOI: 10.1007/s00213-020-05678-7  0.808
2020 Pallarés V, Dudek M, Moreno A, Pérez-Ramírez Ú, Moratal D, Haaranen M, Ciccocioppo R, Sommer WH, Canals S, Hyytiä P. Neuroimaging reveals functionally distinct neuronal networks associated with high-level alcohol consumption in two genetic rat models. Behavioural Pharmacology. PMID 32925226 DOI: 10.1097/Fbp.0000000000000582  0.494
2020 Domi E, Domi A, Ubaldi M, Somaini L, Demopulos G, Gaitanaris G, Ciccocioppo R. Further evidence for the involvement of the PPARγ system on alcohol intake and sensitivity in rodents. Psychopharmacology. PMID 32676772 DOI: 10.1007/S00213-020-05586-W  0.518
2020 De Santis S, Cosa-Linan A, Garcia-Hernandez R, Dmytrenko L, Vargova L, Vorisek I, Stopponi S, Bach P, Kirsch P, Kiefer F, Ciccocioppo R, Sykova E, Moratal D, Sommer WH, Canals S. Chronic alcohol consumption alters extracellular space geometry and transmitter diffusion in the brain. Science Advances. 6: eaba0154. PMID 32637601 DOI: 10.1126/Sciadv.Aba0154  0.468
2020 Fotio Y, Borruto AM, Benvenuti F, Demopulos G, Gaitanaris G, Roberto M, Ciccocioppo R. Activation of peroxisome proliferator-activated receptor γ reduces alcohol drinking and seeking by modulating multiple mesocorticolimbic regions in rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 32610339 DOI: 10.1038/S41386-020-0754-4  0.84
2020 Haass-Koffler CL, Cannella N, Ciccocioppo R. Translational dynamics of alcohol tolerance of preclinical models and human laboratory studies. Experimental and Clinical Psychopharmacology. PMID 32212746 DOI: 10.1037/Pha0000366  0.454
2020 Ciccocioppo R, Borruto AM, Benvenuti F, Petrella M, Soverchia L, Cannella N, Roberto M, Weiss F. The Nociceptin/Orphanin Fq Nop Receptor System as a Therapeutic Target for the Treatment of Substance Use and Stress Related Disorders: Preclinical Evidence Biological Psychiatry. 87: S80. DOI: 10.1016/J.Biopsych.2020.02.227  0.673
2019 Bilel S, Tirri M, Arfè R, Stopponi S, Soverchia L, Ciccocioppo R, Frisoni P, Strano-Rossi S, Miliano C, De-Giorgio F, Serpelloni G, Fantinati A, De Luca MA, Neri M, Marti M. Pharmacological and Behavioral Effects of the Synthetic Cannabinoid AKB48 in Rats. Frontiers in Neuroscience. 13: 1163. PMID 31736697 DOI: 10.3389/Fnins.2019.01163  0.398
2019 Borruto AM, Fotio Y, Stopponi S, Brunori G, Petrella M, Caputi FF, Romualdi P, Candeletti S, Narendran R, Rorick-Kehn LM, Ubaldi M, Weiss F, Ciccocioppo R. NOP receptor antagonism reduces alcohol drinking in male and female rats through mechanisms involving the central amygdala and ventral tegmental area. British Journal of Pharmacology. PMID 31713848 DOI: 10.1111/Bph.14915  0.852
2019 Flanigan M, Tollefson S, Himes ML, Jordan R, Roach K, Stoughton C, Lopresti B, Mason NS, Ciccocioppo R, Narendran R. Acute Elevations in Cortisol Increase the In Vivo Binding of [C]NOP-1A to Nociceptin Receptors: A Novel Imaging Paradigm to Study the Interaction Between Stress- and Antistress-Regulating Neuropeptides. Biological Psychiatry. PMID 31706582 DOI: 10.1016/J.Biopsych.2019.09.013  0.319
2019 Domi E, Caputi FF, Romualdi P, Domi A, Scuppa G, Candeletti S, Atkins A, Heilig M, Demopulos G, Gaitanaris G, Ciccocioppo R, Ubaldi M. Activation of PPARγ attenuates the expression of physical and affective nicotine withdrawal symptoms through mechanisms involving amygdala and hippocampus neurotransmission. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 31685649 DOI: 10.1523/Jneurosci.1922-19.2019  0.554
2019 Brunori G, Weger M, Schoch J, Targowska-Duda K, Barnes M, Borruto AM, Rorick-Kehn LM, Zaveri NT, Pintar JE, Ciccocioppo R, Toll L, Cippitelli A. NOP receptor antagonists decrease alcohol drinking in the dark in C57BL/6J mice. Alcoholism, Clinical and Experimental Research. PMID 31386211 DOI: 10.1111/Acer.14165  0.514
2019 Fotio Y, Aboufares El Alaoui A, Borruto AM, Acciarini S, Giordano A, Ciccocioppo R. Efficacy of a Combination of N-Palmitoylethanolamide, Beta-Caryophyllene, Carnosic Acid, and Myrrh Extract on Chronic Neuropathic Pain: A Preclinical Study. Frontiers in Pharmacology. 10: 711. PMID 31316381 DOI: 10.3389/Fphar.2019.00711  0.727
2019 Cannella N, Ubaldi M, Masi A, Bramucci M, Roberto M, Bifone A, Ciccocioppo R. Building better strategies to develop new medications in Alcohol Use Disorder: Learning from past success and failure to shape a brighter future. Neuroscience and Biobehavioral Reviews. PMID 31112713 DOI: 10.1016/J.Neubiorev.2019.05.014  0.568
2019 Narendran R, Tollefson S, Himes ML, Paris J, Lopresti B, Ciccocioppo R, Mason NS. Nociceptin Receptors Upregulated in Cocaine Use Disorder: A Positron Emission Tomography Imaging Study Using [C]NOP-1A. The American Journal of Psychiatry. appiajp201918081007. PMID 31055968 DOI: 10.1176/Appi.Ajp.2019.18081007  0.436
2019 Li H, Scuppa G, Shen Q, Masi A, Nasuti C, Cannella N, Ciccocioppo R. NOP Receptor Agonist Ro 64-6198 Decreases Escalation of Cocaine Self-Administration in Rats Genetically Selected for Alcohol Preference. Frontiers in Psychiatry. 10: 176. PMID 30984046 DOI: 10.3389/Fpsyt.2019.00176  0.474
2019 Ciccocioppo R, Borruto AM, Domi A, Teshima K, Cannella N, Weiss F. NOP-Related Mechanisms in Substance Use Disorders. Handbook of Experimental Pharmacology. PMID 30968214 DOI: 10.1007/164_2019_209  0.71
2019 De Santis S, Bach P, Pérez-Cervera L, Cosa-Linan A, Weil G, Vollstädt-Klein S, Hermann D, Kiefer F, Kirsch P, Ciccocioppo R, Sommer WH, Canals S. Microstructural White Matter Alterations in Men With Alcohol Use Disorder and Rats With Excessive Alcohol Consumption During Early Abstinence. Jama Psychiatry. PMID 30942831 DOI: 10.1001/Jamapsychiatry.2019.0318  0.462
2019 Domi A, Stopponi S, Domi E, Ciccocioppo R, Cannella N. Sub-dimensions of Alcohol Use Disorder in Alcohol Preferring and Non-preferring Rats, a Comparative Study. Frontiers in Behavioral Neuroscience. 13: 3. PMID 30760988 DOI: 10.3389/Fnbeh.2019.00003  0.517
2018 Caputi FF, Rullo L, Acquas E, Ciccocioppo R, Candeletti S, Romualdi P. Evidence of a PPARγ-mediated mechanism in the ability of Withania somnifera to attenuate tolerance to the antinociceptive effects of morphine. Pharmacological Research. 139: 422-430. PMID 30503841 DOI: 10.1016/J.Phrs.2018.11.033  0.358
2018 Bifone A, Gozzi A, Cippitelli A, Matzeu A, Domi E, Li H, Scuppa G, Cannella N, Ubaldi M, Weiss F, Ciccocioppo R. phMRI, neurochemical and behavioral responses to psychostimulants distinguishing genetically selected alcohol-preferring from genetically heterogenous rats. Addiction Biology. PMID 30328656 DOI: 10.1111/Adb.12671  0.848
2018 Jones JD, Bisaga A, Metz VE, Manubay JM, Mogali S, Ciccocioppo R, Madera G, Doernberg M, Comer SD. The PPARγ Agonist Pioglitazone Fails to Alter the Abuse Potential of Heroin, But Does Reduce Heroin Craving and Anxiety. Journal of Psychoactive Drugs. 1-12. PMID 30204554 DOI: 10.1080/02791072.2018.1508789  0.342
2018 Alen F, Decara J, Brunori G, You ZB, Bühler KM, López-Moreno JA, Cippitelli A, Pavon J, Suárez J, Gardner EL, de la Torre R, Ciccocioppo R, Serrano A, de Fonseca FR. PPARα/CB1 receptor dual ligands as a novel therapy for alcohol use disorder: evaluation of a novel oleic acid conjugate in preclinical rat models. Biochemical Pharmacology. PMID 30195735 DOI: 10.1016/J.Bcp.2018.09.008  0.532
2018 Logrip ML, Walker JR, Ayanwuyi LO, Sabino V, Ciccocioppo R, Koob GF, Zorrilla EP. Evaluation of Alcohol Preference and Drinking in msP Rats Bearing aPromoter Polymorphism. Frontiers in Psychiatry. 9: 28. PMID 29497387 DOI: 10.3389/Fpsyt.2018.00028  0.613
2018 Micheli L, Lucarini E, Corti F, Ciccocioppo R, Calò G, Rizzi A, Ghelardini C, Di Cesare Mannelli L. Involvement of the N/OFQ-NOP system in rat morphine antinociceptive tolerance: are astrocytes the crossroad? European Journal of Pharmacology. PMID 29378191 DOI: 10.1016/J.Ejphar.2018.01.039  0.364
2017 Ruggeri B, Macare C, Stopponi S, Jia T, Carvalho FM, Robert G, Banaschewski T, Bokde ALW, Bromberg U, Büchel C, Cattrell A, Conrod PJ, Desrivières S, Flor H, Frouin V, ... ... Ciccocioppo R, et al. Methylation of OPRL1 mediates the effect of psychosocial stress on binge drinking in adolescents. Journal of Child Psychology and Psychiatry, and Allied Disciplines. PMID 29197086 DOI: 10.1111/Jcpp.12843  0.393
2017 Shen Q, Deng Y, Ciccocioppo R, Cannella N. Cebranopadol, a Mixed Opioid Agonist, Reduces Cocaine Self-administration through Nociceptin Opioid and Mu Opioid Receptors. Frontiers in Psychiatry. 8: 234. PMID 29180970 DOI: 10.3389/Fpsyt.2017.00234  0.402
2017 Hansson AC, Koopmann A, Uhrig S, Bühler S, Domi E, Kiessling E, Ciccocioppo R, Froemke RC, Grinevich V, Kiefer F, Sommer WH, Vollstädt-Klein S, Spanagel R. Oxytocin Reduces Alcohol Cue-Reactivity in Alcohol Dependent Rats and Humans. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 29090683 DOI: 10.1038/Npp.2017.257  0.54
2017 Stopponi S, Fotio Y, Domi A, Borruto AM, Natividad L, Roberto M, Ciccocioppo R, Cannella N. Inhibition of fatty acid amide hydrolase in the central amygdala alleviates co-morbid expression of innate anxiety and excessive alcohol intake. Addiction Biology. PMID 29071769 DOI: 10.1111/Adb.12573  0.834
2017 Perez-Ramirez U, Diaz-Parra A, Ciccocioppo R, Canals S, Moratal D. Brain functional connectivity alterations in a rat model of excessive alcohol drinking: A resting-state network analysis. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 2017: 3016-3019. PMID 29060533 DOI: 10.1109/EMBC.2017.8037492  0.318
2017 Jones JD, Comer SD, Metz VE, Manubay JM, Mogali S, Ciccocioppo R, Martinez S, Mumtaz M, Bisaga A. Pioglitazone, a PPARγ agonist, reduces nicotine craving in humans, with marginal effects on abuse potential. Pharmacology, Biochemistry, and Behavior. PMID 29020601 DOI: 10.1016/J.Pbb.2017.10.002  0.301
2017 Micioni Di Bonaventura MV, Ubaldi M, Giusepponi ME, Rice KC, Massi M, Ciccocioppo R, Cifani C. Hypothalamic CRF1 receptor mechanisms are not sufficient to account for binge-like palatable food consumption in female rats. The International Journal of Eating Disorders. PMID 28833350 DOI: 10.1002/Eat.22767  0.417
2017 Narendran R, Ciccocioppo R, Lopresti B, Paris J, Himes ML, Mason NS. Nociceptin Receptors in Alcohol Use Disorders: A Positron Emission Tomography Study Using [(11)C]NOP-1A. Biological Psychiatry. PMID 28711193 DOI: 10.1016/J.Biopsych.2017.05.019  0.451
2017 Kirson D, Oleata CS, Parsons LH, Ciccocioppo R, Roberto M. CB1 and ethanol effects on glutamatergic transmission in the central amygdala of male and female msP and Wistar rats. Addiction Biology. PMID 28656627 DOI: 10.1111/Adb.12525  0.746
2017 Kallupi M, Shen Q, de Guglielmo G, Yasuda D, Journigan VB, Zaveri NT, Ciccocioppo R. Buprenorphine requires concomitant activation of NOP and MOP receptors to reduce cocaine consumption. Addiction Biology. PMID 28635181 DOI: 10.1111/Adb.12513  0.705
2017 Egervari G, Ciccocioppo R, Jentsch JD, Hurd YL. Shaping vulnerability to addiction - the contribution of behavior, neural circuits and molecular mechanisms. Neuroscience and Biobehavioral Reviews. PMID 28571877 DOI: 10.1016/J.Neubiorev.2017.05.019  0.312
2017 Natividad LA, Buczynski MW, Herman MA, Kirson D, Oleata CS, Irimia C, Polis I, Ciccocioppo R, Roberto M, Parsons LH. Constitutive Increases in Amygdalar Corticotropin-Releasing Factor and Fatty Acid Amide Hydrolase Drive an Anxious Phenotype. Biological Psychiatry. PMID 28209423 DOI: 10.1016/J.Biopsych.2017.01.005  0.704
2017 Cippitelli A, Domi E, Ubaldi M, Douglas JC, Li HW, Demopulos G, Gaitanaris G, Roberto M, Drew PD, Kane CJ, Ciccocioppo R. Protection against alcohol-induced neuronal and cognitive damage by the PPARγ receptor agonist pioglitazone. Brain, Behavior, and Immunity. PMID 28167117 DOI: 10.1016/J.Bbi.2017.02.001  0.622
2017 Ciccocioppo R, Casarola F, Borruto A, Domi A, Yannick F, Cannella N, Weiss F. S11-1NOVEL FINDINGS ON NOCICEPTIN RECEPTOR SYSTEM AS A TREATMENT TARGET FOR ALCOHOLISM Alcohol and Alcoholism. 52: i4-i30. DOI: 10.1093/Alcalc/Agx075.38  0.658
2017 Di Bonaventura MVM, Ubaldi M, Giusepponi ME, Rice KC, Massi M, Ciccocioppo R, Cifani C. Extra-hypothalamic CRF-1 receptor mechanisms in frustration stress-induced binge-like palatable food consumption in female rats Alcohol. 60: 239. DOI: 10.1016/J.Alcohol.2017.02.336  0.412
2017 Fotio Y, Ciccocioppo R. Activation of PPARγ modulates the mesolimbic dopamine transmission and attenuates alcohol drinking in alcohol-preferring rats Alcohol. 60: 238. DOI: 10.1016/J.Alcohol.2017.02.332  0.8
2017 Borruto A, Stopponi S, Mondaini M, Ubaldi M, Ciccocioppo R. A novel NOP receptor antagonist decreases alcohol behavior in Marchigian Sardinian alcohol-preferring (msP) rats Alcohol. 60: 233-234. DOI: 10.1016/J.Alcohol.2017.02.314  0.528
2017 Gaitanaris G, Demopulos G, Ciccocioppo R. Phosphodiesterase type 7 inhibition: A novel mechanism for reduction of alcohol drinking and relapse to alcohol seeking Alcohol. 60: 210. DOI: 10.1016/J.Alcohol.2017.02.214  0.442
2016 Domi E, Uhrig S, Soverchia L, Spanagel R, Hansson AC, Barbier E, Heilig M, Ciccocioppo R, Ubaldi M. Genetic deletion of neuronal PPARγ enhances the emotional response to acute stress and exacerbates anxiety: An effect reversed by rescue of amygdala PPARγ function. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 27810934 DOI: 10.1523/Jneurosci.4127-15.2016  0.503
2016 de Guglielmo G, Kallupi M, Scuppa G, Demopulos G, Gaitanaris G, Ciccocioppo R. Pioglitazone attenuates the opioid withdrawal and vulnerability to relapse to heroin seeking in rodents. Psychopharmacology. PMID 27714428 DOI: 10.1007/S00213-016-4452-1  0.689
2016 Kallupi M, Scuppa G, de Guglielmo G, Calò G, Weiss F, Statnick MA, Rorick-Kehn LM, Ciccocioppo R. Genetic Deletion of the Nociceptin/Orphanin FQ Receptor in the Rat Confers Resilience to the Development of Drug Addiction. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 27562376 DOI: 10.1038/Npp.2016.171  0.814
2016 Galesi FL, Ayanwuyi LO, Mijares MG, Cippitelli A, Cannella N, Ciccocioppo R, Ubaldi M. Role of Hypothalamic-Pituitary-Adrenal axis and Corticotropin-Releasing Factor stress system on cue-induced relapse to alcohol seeking. European Journal of Pharmacology. PMID 27316790 DOI: 10.1016/J.Ejphar.2016.06.020  0.489
2016 Cosa A, Moreno A, Pacheco-Torres J, Ciccocioppo R, Hyytiä P, Sommer WH, Moratal D, Canals S. Multi-modal MRI classifiers identify excessive alcohol consumption and treatment effects in the brain. Addiction Biology. PMID 27273582 DOI: 10.1111/Adb.12418  0.449
2016 Cannella N, Kallupi M, Li HW, Stopponi S, Cifani C, Ciccocioppo R, Ubaldi M. Neuropeptide S differently modulates alcohol-related behaviors in alcohol-preferring and non-preferring rats. Psychopharmacology. PMID 27235017 DOI: 10.1007/S00213-016-4333-7  0.766
2016 Rorick-Kehn LM, Ciccocioppo R, Wong CJ, Witkin JM, Martinez-Grau MA, Stopponi S, Adams BL, Katner JS, Perry KW, Toledo MA, Diaz N, Lafuente C, Jiménez A, Benito A, Pedregal C, et al. A Novel, Orally Bioavailable Nociceptin Receptor Antagonist, LY2940094, Reduces Ethanol Self-Administration and Ethanol Seeking in Animal Models. Alcoholism, Clinical and Experimental Research. PMID 27084498 DOI: 10.1111/Acer.13052  0.675
2016 Ubaldi M, Cannella N, Ciccocioppo R. Emerging targets for addiction neuropharmacology: From mechanisms to therapeutics. Progress in Brain Research. 224: 251-84. PMID 26822362 DOI: 10.1016/Bs.Pbr.2015.07.018  0.319
2015 Herman MA, Varodayan FP, Oleata CS, Luu G, Kirson D, Heilig M, Ciccocioppo R, Roberto M. Glutamatergic transmission in the central nucleus of the amygdala is selectively altered in Marchigian Sardinian alcohol-preferring rats: Alcohol and CRF effects. Neuropharmacology. 102: 21-31. PMID 26519902 DOI: 10.1016/J.Neuropharm.2015.10.027  0.708
2015 Jones JD, Sullivan MA, Manubay JM, Mogali S, Metz VE, Ciccocioppo R, Comer SD. TEMPORARY REMOVAL: The effects of pioglitazone, a PPARγ receptor agonist, on the abuse liability of oxycodone among nondependent opioid users. Physiology & Behavior. PMID 26455893 DOI: 10.1016/J.Physbeh.2015.10.006  0.357
2015 Pucci M, Micioni Di Bonaventura MV, Giusepponi ME, Romano A, Filaferro M, Maccarrone M, Ciccocioppo R, Cifani C, D'Addario C. Epigenetic regulation of nociceptin/orphanin FQ and corticotropin-releasing factor system genes in frustration stress-induced binge-like palatable food consumption. Addiction Biology. PMID 26387568 DOI: 10.1111/Adb.12303  0.371
2015 Scuppa G, Cippitelli A, Toll L, Ciccocioppo R, Ubaldi M. Varenicline decreases nicotine but not alcohol self-administration in genetically selected Marchigian Sardinian alcohol-preferring (msP) rats. Drug and Alcohol Dependence. 156: 126-32. PMID 26383997 DOI: 10.1016/J.Drugalcdep.2015.09.002  0.483
2015 Ayanwuyi LO, Stopponi S, Ubaldi M, Cippitelli A, Nasuti C, Damadzic R, Heilig M, Schank J, Cheng K, Rice KC, Ciccocioppo R. Neurokinin 1 receptor blockade in the medial amygdala attenuates alcohol drinking in rats with innate anxiety but not in wistar rats. British Journal of Pharmacology. PMID 26275374 DOI: 10.1111/Bph.13280  0.617
2015 Ubaldi M, Giordano A, Severi I, Li H, Kallupi M, de Guglielmo G, Ruggeri B, Stopponi S, Ciccocioppo R, Cannella N. Activation of Hypocretin-1/Orexin-A Neurons Projecting to the Bed Nucleus of the Stria Terminalis and Paraventricular Nucleus Is Critical for Reinstatement of Alcohol Seeking by Neuropeptide S. Biological Psychiatry. PMID 26055195 DOI: 10.1016/J.Biopsych.2015.04.021  0.728
2015 Bilbao A, Serrano A, Cippitelli A, Pavón FJ, Giuffrida A, Suárez J, García-Marchena N, Baixeras E, Gómez de Heras R, Orio L, Alén F, Ciccocioppo R, Cravatt BF, Parsons LH, Piomelli D, et al. Role of the satiety factor oleoylethanolamide in alcoholism. Addiction Biology. PMID 26037332 DOI: 10.1111/Adb.12276  0.748
2015 Micheli L, Di Cesare Mannelli L, Guerrini R, Trapella C, Zanardelli M, Ciccocioppo R, Rizzi A, Ghelardini C, Calò G. Acute and subchronic antinociceptive effects of nociceptin/orphanin FQ receptor agonists infused by intrathecal route in rats. European Journal of Pharmacology. 754: 73-81. PMID 25704616 DOI: 10.1016/J.Ejphar.2015.02.020  0.363
2015 de Guglielmo G, Melis M, De Luca MA, Kallupi M, Li HW, Niswender K, Giordano A, Senzacqua M, Somaini L, Cippitelli A, Gaitanaris G, Demopulos G, Damadzic R, Tapocik J, Heilig M, ... Ciccocioppo R, et al. PPARc activation attenuates opioid consumption and modulates mesolimbic dopamine transmission. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 40: 1052. PMID 25668637 DOI: 10.1038/Npp.2014.305  0.745
2015 de Guglielmo G, Melis M, De Luca MA, Kallupi M, Li HW, Niswender K, Giordano A, Senzacqua M, Somaini L, Cippitelli A, Gaitanaris G, Demopulos G, Damadzic R, Tapocik J, Heilig M, ... Ciccocioppo R, et al. PPARγ activation attenuates opioid consumption and modulates mesolimbic dopamine transmission. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 40: 927-37. PMID 25311134 DOI: 10.1038/npp.2014.268  0.729
2015 Cippitelli A, Ayanwuyi LO, Barbier E, Domi E, Lerma-Cabrera JM, Carvajal F, Scuppa G, Li H, Ubaldi M, Heilig M, Roberto M, Ciccocioppo R. Polymorphism in the corticotropin-releasing factor receptor 1 (CRF1-R) gene plays a role in shaping the high anxious phenotype of Marchigian Sardinian alcohol-preferring (msP) rats. Psychopharmacology. 232: 1083-93. PMID 25260340 DOI: 10.1007/S00213-014-3743-7  0.71
2015 de Guglielmo G, Martin-Fardon R, Teshima K, Ciccocioppo R, Weiss F. MT-7716, a potent NOP receptor agonist, preferentially reduces ethanol seeking and reinforcement in post-dependent rats. Addiction Biology. 20: 643-51. PMID 24930632 DOI: 10.1111/Adb.12157  0.744
2014 Ghazal P, Corsi M, Roth A, Faggioni F, Corti C, Merlo Pick E, Pucciarelli S, Ciccocioppo R, Ubaldi M. Paradoxical response to the sedative effects of diazepam and alcohol in C57BL/6J mice lacking the neuropeptide S receptor. Peptides. 61: 107-13. PMID 25240770 DOI: 10.1016/J.Peptides.2014.09.010  0.409
2014 Micioni Di Bonaventura MV, Ciccocioppo R, Romano A, Bossert JM, Rice KC, Ubaldi M, St Laurent R, Gaetani S, Massi M, Shaham Y, Cifani C. Role of bed nucleus of the stria terminalis corticotrophin-releasing factor receptors in frustration stress-induced binge-like palatable food consumption in female rats with a history of food restriction. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 11316-24. PMID 25143612 DOI: 10.1523/Jneurosci.1854-14.2014  0.396
2014 de Guglielmo G, Kallupi M, Scuppa G, Stopponi S, Demopulos G, Gaitanaris G, Ciccocioppo R. Analgesic tolerance to morphine is regulated by PPARγ. British Journal of Pharmacology. 171: 5407-16. PMID 25048682 DOI: 10.1111/Bph.12851  0.663
2014 Ciccocioppo R, Stopponi S, Economidou D, Kuriyama M, Kinoshita H, Heilig M, Roberto M, Weiss F, Teshima K. Chronic treatment with novel brain-penetrating selective NOP receptor agonist MT-7716 reduces alcohol drinking and seeking in the rat. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 2601-10. PMID 24863033 DOI: 10.1038/Npp.2014.113  0.814
2014 Kallupi M, Oleata CS, Luu G, Teshima K, Ciccocioppo R, Roberto M. MT-7716, a novel selective nonpeptidergic NOP receptor agonist, effectively blocks ethanol-induced increase in GABAergic transmission in the rat central amygdala. Frontiers in Integrative Neuroscience. 8: 18. PMID 24600360 DOI: 10.3389/Fnint.2014.00018  0.788
2014 Stopponi S, Soverchia L, Ubaldi M, Cippitelli A, Serpelloni G, Ciccocioppo R. Chronic THC during adolescence increases the vulnerability to stress-induced relapse to heroin seeking in adult rats. European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology. 24: 1037-45. PMID 24412506 DOI: 10.1016/J.Euroneuro.2013.12.012  0.409
2014 Ciccocioppo R, de Guglielmo G, Hansson AC, Ubaldi M, Kallupi M, Cruz MT, Oleata CS, Heilig M, Roberto M. Restraint stress alters nociceptin/orphanin FQ and CRF systems in the rat central amygdala: significance for anxiety-like behaviors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 363-72. PMID 24403138 DOI: 10.1523/Jneurosci.2400-13.2014  0.778
2014 Witkin JM, Statnick MA, Rorick-Kehn LM, Pintar JE, Ansonoff M, Chen Y, Tucker RC, Ciccocioppo R. The biology of Nociceptin/Orphanin FQ (N/OFQ) related to obesity, stress, anxiety, mood, and drug dependence. Pharmacology & Therapeutics. 141: 283-99. PMID 24189487 DOI: 10.1016/J.Pharmthera.2013.10.011  0.398
2014 Ciccocioppo R, Li H, de Guglielmo G, Ubaldi M, Soverchia L, Caffino L, Fumagalli F, Demopulos G, Gaitanaris G. SY40-2 * PHOSPHODIESTERASE TYPE 7: A NOVEL TARGET FOR SMOKING CESSATION -PRECLINICAL EVIDENCE- Alcohol and Alcoholism. 49: i34-i34. DOI: 10.1093/Alcalc/Agu052.166  0.366
2014 Nasuti C, Bello FD, Pigini M, Ciccocioppo R, Ubaldi M. Effects of allyphenyline on chronic alcohol intoxication model Alcohol. 48: 188-188. DOI: 10.1016/J.Alcohol.2014.01.003  0.425
2013 Thorsell A, Tapocik JD, Liu K, Zook M, Bell L, Flanigan M, Patnaik S, Marugan J, Damadzic R, Dehdashti SJ, Schwandt ML, Southall N, Austin CP, Eskay R, Ciccocioppo R, et al. A novel brain penetrant NPS receptor antagonist, NCGC00185684, blocks alcohol-induced ERK-phosphorylation in the central amygdala and decreases operant alcohol self-administration in rats. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 10132-42. PMID 23761908 DOI: 10.1523/Jneurosci.4742-12.2013  0.664
2013 Ghazal P, Ciccocioppo R, Ubaldi M. Morphine dependence is associated with changes in neuropeptide S receptor expression and function in rat brain. Peptides. 46: 6-12. PMID 23684726 DOI: 10.1016/J.Peptides.2013.05.001  0.402
2013 Ubaldi M, Bifone A, Ciccocioppo R. Translational approach to develop novel medications on alcohol addiction: focus on neuropeptides. Current Opinion in Neurobiology. 23: 684-91. PMID 23648086 DOI: 10.1016/J.Conb.2013.04.009  0.45
2013 Ayanwuyi LO, Carvajal F, Lerma-Cabrera JM, Domi E, Björk K, Ubaldi M, Heilig M, Roberto M, Ciccocioppo R, Cippitelli A. Role of a genetic polymorphism in the corticotropin-releasing factor receptor 1 gene in alcohol drinking and seeking behaviors of marchigian sardinian alcohol-preferring rats. Frontiers in Psychiatry. 4: 23. PMID 23630503 DOI: 10.3389/Fpsyt.2013.00023  0.738
2013 Stopponi S, de Guglielmo G, Somaini L, Cippitelli A, Cannella N, Kallupi M, Ubaldi M, Heilig M, Demopulos G, Gaitanaris G, Ciccocioppo R. Activation of PPARγ by pioglitazone potentiates the effects of naltrexone on alcohol drinking and relapse in msP rats. Alcoholism, Clinical and Experimental Research. 37: 1351-60. PMID 23550625 DOI: 10.1111/Acer.12091  0.801
2013 Micioni Di Bonaventura MV, Ubaldi M, Liberati S, Ciccocioppo R, Massi M, Cifani C. Caloric restriction increases the sensitivity to the hyperphagic effect of nociceptin/orphanin FQ limiting its ability to reduce binge eating in female rats. Psychopharmacology. 228: 53-63. PMID 23455592 DOI: 10.1007/S00213-013-3013-0  0.388
2013 Gozzi A, Agosta F, Massi M, Ciccocioppo R, Bifone A. Reduced limbic metabolism and fronto-cortical volume in rats vulnerable to alcohol addiction. Neuroimage. 69: 112-9. PMID 23261637 DOI: 10.1016/J.Neuroimage.2012.12.015  0.5
2013 Herman MA, Kallupi M, Luu G, Oleata CS, Heilig M, Koob GF, Ciccocioppo R, Roberto M. Enhanced GABAergic transmission in the central nucleus of the amygdala of genetically selected Marchigian Sardinian rats: alcohol and CRF effects. Neuropharmacology. 67: 337-48. PMID 23220399 DOI: 10.1016/J.Neuropharm.2012.11.026  0.834
2013 Nasuti C, Carloni M, Fedeli D, Gabbianelli R, Di Stefano A, Serafina CL, Silva I, Domingues V, Ciccocioppo R. Effects of early life permethrin exposure on spatial working memory and on monoamine levels in different brain areas of pre-senescent rats. Toxicology. 303: 162-8. PMID 23174539 DOI: 10.1016/J.Tox.2012.09.016  0.354
2013 Kallupi M, de Guglielmo G, Cannella N, Li HW, Caló G, Guerrini R, Ubaldi M, Renger JJ, Uebele VN, Ciccocioppo R. Hypothalamic neuropeptide S receptor blockade decreases discriminative cue-induced reinstatement of cocaine seeking in the rat. Psychopharmacology. 226: 347-55. PMID 23149909 DOI: 10.1007/S00213-012-2910-Y  0.704
2013 Cannella N, Kallupi M, Ruggeri B, Ciccocioppo R, Ubaldi M. The role of the neuropeptide S system in addiction: focus on its interaction with the CRF and hypocretin/orexin neurotransmission. Progress in Neurobiology. 100: 48-59. PMID 23041581 DOI: 10.1016/J.Pneurobio.2012.09.005  0.663
2013 Aujla H, Cannarsa R, Romualdi P, Ciccocioppo R, Martin-Fardon R, Weiss F. Modification of anxiety-like behaviors by nociceptin/orphanin FQ (N/OFQ) and time-dependent changes in N/OFQ-NOP gene expression following ethanol withdrawal. Addiction Biology. 18: 467-79. PMID 22804785 DOI: 10.1111/J.1369-1600.2012.00466.X  0.821
2013 de Guglielmo G, Cippitelli A, Somaini L, Gerra G, Li H, Stopponi S, Ubaldi M, Kallupi M, Ciccocioppo R. Pregabalin reduces cocaine self-administration and relapse to cocaine seeking in the rat. Addiction Biology. 18: 644-53. PMID 22734646 DOI: 10.1111/J.1369-1600.2012.00468.X  0.717
2013 Ciccocioppo R. Genetically selected alcohol preferring rats to model human alcoholism. Current Topics in Behavioral Neurosciences. 13: 251-69. PMID 22328453 DOI: 10.1007/7854_2012_199  0.477
2013 Bonaventura MMD, Ubaldi M, Rice K, Massi M, Ciccocioppo R, Cifani C. P.1.h.028 Selective antagonism at CRF1 receptor as a novel pharmacological treatment for binge-type eating disorders European Neuropsychopharmacology. 23. DOI: 10.1016/S0924-977X(13)70404-8  0.3
2013 Canals S, Moreno A, Pallarés V, Pacheco-Torres J, Moratal D, Cruz FDl, Fernández B, Ciccocioppo R, Hyytiä P, Sommer W. S.14.02 Testing the effect of alcohol intake and naltrexone treatment on brain networks using combined rsMRI/MEMRI in rats European Neuropsychopharmacology. 23. DOI: 10.1016/S0924-977X(13)70180-9  0.445
2013 Kallupi M, Ciccocioppo R. Preclinical Animal Studies: Cocaine Biological Research On Addiction. 121-127. DOI: 10.1016/B978-0-12-398335-0.00013-3  0.63
2012 Schank JR, Ryabinin AE, Giardino WJ, Ciccocioppo R, Heilig M. Stress-related neuropeptides and addictive behaviors: beyond the usual suspects. Neuron. 76: 192-208. PMID 23040815 DOI: 10.1016/J.Neuron.2012.09.026  0.531
2012 Karlsson C, Zook M, Ciccocioppo R, Gehlert DR, Thorsell A, Heilig M, Cippitelli A. Melanin-concentrating hormone receptor 1 (MCH1-R) antagonism: reduced appetite for calories and suppression of addictive-like behaviors. Pharmacology, Biochemistry, and Behavior. 102: 400-6. PMID 22705492 DOI: 10.1016/J.Pbb.2012.06.010  0.584
2012 Piccoli L, Micioni Di Bonaventura MV, Cifani C, Costantini VJ, Massagrande M, Montanari D, Martinelli P, Antolini M, Ciccocioppo R, Massi M, Merlo-Pich E, Di Fabio R, Corsi M. Role of orexin-1 receptor mechanisms on compulsive food consumption in a model of binge eating in female rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 37: 1999-2011. PMID 22569505 DOI: 10.1038/Npp.2012.48  0.392
2012 Cippitelli A, Damadzic R, Singley E, Thorsell A, Ciccocioppo R, Eskay RL, Heilig M. Pharmacological blockade of corticotropin-releasing hormone receptor 1 (CRH1R) reduces voluntary consumption of high alcohol concentrations in non-dependent Wistar rats. Pharmacology, Biochemistry, and Behavior. 100: 522-9. PMID 22036774 DOI: 10.1016/J.Pbb.2011.10.016  0.662
2012 Stopponi S, Somaini L, Cippitelli A, de Guglielmo G, Kallupi M, Cannella N, Gerra G, Massi M, Ciccocioppo R. Pregabalin reduces alcohol drinking and relapse to alcohol seeking in the rat. Psychopharmacology. 220: 87-96. PMID 21887495 DOI: 10.1007/S00213-011-2457-3  0.76
2011 Cippitelli A, Astarita G, Duranti A, Caprioli G, Ubaldi M, Stopponi S, Kallupi M, Sagratini G, Rodrìguez de Fonseca F, Piomelli D, Ciccocioppo R. Endocannabinoid regulation of acute and protracted nicotine withdrawal: effect of FAAH inhibition. Plos One. 6: e28142. PMID 22140525 DOI: 10.1371/Journal.Pone.0028142  0.727
2011 Somaini L, Donnini C, Raggi MA, Amore M, Ciccocioppo R, Saracino MA, Kalluppi M, Malagoli M, Gerra ML, Gerra G. Promising medications for cocaine dependence treatment. Recent Patents On Cns Drug Discovery. 6: 146-60. PMID 21599628 DOI: 10.2174/157488911795933893  0.338
2011 Stopponi S, Somaini L, Cippitelli A, Cannella N, Braconi S, Kallupi M, Ruggeri B, Heilig M, Demopulos G, Gaitanaris G, Massi M, Ciccocioppo R. Activation of nuclear PPARγ receptors by the antidiabetic agent pioglitazone suppresses alcohol drinking and relapse to alcohol seeking. Biological Psychiatry. 69: 642-9. PMID 21276964 DOI: 10.1016/J.Biopsych.2010.12.010  0.805
2011 Economidou D, Cippitelli A, Stopponi S, Braconi S, Clementi S, Ubaldi M, Martin-Fardon R, Weiss F, Massi M, Ciccocioppo R. Activation of brain NOP receptors attenuates acute and protracted alcohol withdrawal symptoms in the rat. Alcoholism, Clinical and Experimental Research. 35: 747-55. PMID 21223310 DOI: 10.1111/J.1530-0277.2010.01392.X  0.725
2011 Micioni Di B M, Cifani C, Rice K, Ciccocioppo R, Massi M. Effect of the CRF-1 receptor antagonist R121919 on binge eating Appetite. 57: S30. DOI: 10.1016/J.Appet.2011.05.230  0.33
2011 Cifani C, Corsi M, Montanari D, Ciccocioppo R, Massi M, Merlo-Pich E, Piccoli L. Effect of the orexin receptors antagonists in an animal model of binge eating Appetite. 57. DOI: 10.1016/J.Appet.2011.05.229  0.361
2011 Cifani C, Micioni Di B M, Ubaldi M, Ciccocioppo R, Massi M. Cycles of food restriction increase the orexigenic effect of nociceptin/orphanin FQ (N/OFQ) and neuropeptide Y (NPY) in female rats Appetite. 57: S10. DOI: 10.1016/J.Appet.2011.05.146  0.331
2011 Cippitelli A, Cannella N, Braconi S, Duranti A, Tontini A, Bilbao A, DeFonseca FR, Piomelli D, Ciccocioppo R. Erratum to: Increase of brain endocannabinoid anandamide levels by FAAH inhibition and alcohol abuse behaviours in the rat Psychopharmacology. 216: 151-151. DOI: 10.1007/S00213-011-2333-1  0.571
2010 Kallupi M, Cannella N, Economidou D, Ubaldi M, Ruggeri B, Weiss F, Massi M, Marugan J, Heilig M, Bonnavion P, de Lecea L, Ciccocioppo R. Neuropeptide S facilitates cue-induced relapse to cocaine seeking through activation of the hypothalamic hypocretin system. Proceedings of the National Academy of Sciences of the United States of America. 107: 19567-72. PMID 20974945 DOI: 10.1073/Pnas.1004100107  0.792
2010 Cifani C, Micioni Di B MV, Vitale G, Ruggieri V, Ciccocioppo R, Massi M. Effect of salidroside, active principle of Rhodiola rosea extract, on binge eating. Physiology & Behavior. 101: 555-62. PMID 20837037 DOI: 10.1016/J.Physbeh.2010.09.006  0.324
2010 Ruzza C, Rizzi A, Trapella C, Pela' M, Camarda V, Ruggieri V, Filaferro M, Cifani C, Reinscheid RK, Vitale G, Ciccocioppo R, Salvadori S, Guerrini R, Calo' G. Further studies on the pharmacological profile of the neuropeptide S receptor antagonist SHA 68. Peptides. 31: 915-25. PMID 20172007 DOI: 10.1016/J.Peptides.2010.02.012  0.367
2010 Braconi S, Sidhpura N, Aujla H, Martin-Fardon R, Weiss F, Ciccocioppo R. Revisiting intragastric ethanol intubation as a dependence induction method for studies of ethanol reward and motivation in rats. Alcoholism, Clinical and Experimental Research. 34: 538-44. PMID 20028350 DOI: 10.1111/J.1530-0277.2009.01119.X  0.8
2010 Martin-Fardon R, Zorrilla EP, Ciccocioppo R, Weiss F. Role of innate and drug-induced dysregulation of brain stress and arousal systems in addiction: Focus on corticotropin-releasing factor, nociceptin/orphanin FQ, and orexin/hypocretin. Brain Research. 1314: 145-61. PMID 20026088 DOI: 10.1016/J.Brainres.2009.12.027  0.616
2010 Ruggeri B, Braconi S, Cannella N, Kallupi M, Soverchia L, Ciccocioppo R, Ubaldi M. Neuropeptide S receptor gene expression in alcohol withdrawal and protracted abstinence in postdependent rats. Alcoholism, Clinical and Experimental Research. 34: 90-7. PMID 19860802 DOI: 10.1111/J.1530-0277.2009.01070.X  0.765
2010 Gerra G, Zaimovic A, Gerra ML, Ciccocioppo R, Cippitelli A, Serpelloni G, Somaini L. Pharmacology and toxicology of Cannabis derivatives and endocannabinoid agonists. Recent Patents On Cns Drug Discovery. 5: 46-52. PMID 19832688 DOI: 10.2174/157488910789753521  0.339
2010 DB MM, Cifani C, Ciccocioppo R, Massi M. Influence of the ovarian cycle on binge eating evoked in female rats by stress and food restrictions Appetite. 54: 663. DOI: 10.1016/J.Appet.2010.04.137  0.361
2009 Ciccocioppo R, Gehlert DR, Ryabinin A, Kaur S, Cippitelli A, Thorsell A, Lê AD, Hipskind PA, Hamdouchi C, Lu J, Hembre EJ, Cramer J, Song M, McKinzie D, Morin M, et al. Stress-related neuropeptides and alcoholism: CRH, NPY, and beyond. Alcohol (Fayetteville, N.Y.). 43: 491-8. PMID 19913192 DOI: 10.1016/J.Alcohol.2009.08.003  0.794
2009 Fedeli A, Braconi S, Economidou D, Cannella N, Kallupi M, Guerrini R, Calò G, Cifani C, Massi M, Ciccocioppo R. The paraventricular nucleus of the hypothalamus is a neuroanatomical substrate for the inhibition of palatable food intake by neuropeptide S. The European Journal of Neuroscience. 30: 1594-602. PMID 19821837 DOI: 10.1111/J.1460-9568.2009.06948.X  0.706
2009 Fonareva I, Spangler E, Cannella N, Sabino V, Cottone P, Ciccocioppo R, Zorrilla EP, Ryabinin AE. Increased perioculomotor urocortin 1 immunoreactivity in genetically selected alcohol preferring rats. Alcoholism, Clinical and Experimental Research. 33: 1956-65. PMID 19673740 DOI: 10.1111/J.1530-0277.2009.01033.X  0.485
2009 Cifani C, Zanoncelli A, Tessari M, Righetti C, Di Francesco C, Ciccocioppo R, Massi M, Melotto S. Pre-exposure to environmental cues predictive of food availability elicits hypothalamic-pituitary-adrenal axis activation and increases operant responding for food in female rats. Addiction Biology. 14: 397-407. PMID 19413564 DOI: 10.1111/J.1369-1600.2009.00152.X  0.341
2009 Cannella N, Economidou D, Kallupi M, Stopponi S, Heilig M, Massi M, Ciccocioppo R. Persistent increase of alcohol-seeking evoked by neuropeptide S: an effect mediated by the hypothalamic hypocretin system. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 2125-34. PMID 19322167 DOI: 10.1038/Npp.2009.37  0.794
2009 Cifani C, Polidori C, Melotto S, Ciccocioppo R, Massi M. A preclinical model of binge eating elicited by yo-yo dieting and stressful exposure to food: effect of sibutramine, fluoxetine, topiramate, and midazolam. Psychopharmacology. 204: 113-25. PMID 19125237 DOI: 10.1007/S00213-008-1442-Y  0.319
2008 Cippitelli A, Cannella N, Braconi S, Duranti A, Tontini A, Bilbao A, Defonseca FR, Piomelli D, Ciccocioppo R. Increase of brain endocannabinoid anandamide levels by FAAH inhibition and alcohol abuse behaviours in the rat. Psychopharmacology. 198: 449-60. PMID 18446329 DOI: 10.1007/S00213-008-1104-0  0.685
2008 Economidou D, Hansson AC, Weiss F, Terasmaa A, Sommer WH, Cippitelli A, Fedeli A, Martin-Fardon R, Massi M, Ciccocioppo R, Heilig M. Dysregulation of nociceptin/orphanin FQ activity in the amygdala is linked to excessive alcohol drinking in the rat. Biological Psychiatry. 64: 211-8. PMID 18367152 DOI: 10.1016/J.Biopsych.2008.02.004  0.779
2008 Martin-Fardon R, Ciccocioppo R, Aujla H, Weiss F. The dorsal subiculum mediates the acquisition of conditioned reinstatement of cocaine-seeking. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 33: 1827-34. PMID 17957218 DOI: 10.1038/Sj.Npp.1301589  0.79
2008 Cifani C, Polidori C, Ciccocioppo R, Massi M. A reliable model of binge eating in rats Appetite. 51: 358. DOI: 10.1016/J.Appet.2008.04.056  0.334
2007 Cippitelli A, Bilbao A, Gorriti MA, Navarro M, Massi M, Piomelli D, Ciccocioppo R, Rodríguez de Fonseca F. The anandamide transport inhibitor AM404 reduces ethanol self-administration. The European Journal of Neuroscience. 26: 476-86. PMID 17650118 DOI: 10.1111/J.1460-9568.2007.05665.X  0.674
2007 Economidou D, Mattioli L, Ubaldi M, Lourdusamy A, Soverchia L, Hardiman G, Campolongo P, Cuomo V, Ciccocioppo R. Role of cannabinoidergic mechanisms in ethanol self-administration and ethanol seeking in rat adult offspring following perinatal exposure to Delta9-tetrahydrocannabinol. Toxicology and Applied Pharmacology. 223: 73-85. PMID 17618662 DOI: 10.1016/J.Taap.2007.05.008  0.53
2007 Campolongo P, Trezza V, Cassano T, Gaetani S, Morgese MG, Ubaldi M, Soverchia L, Antonelli T, Ferraro L, Massi M, Ciccocioppo R, Cuomo V. Perinatal exposure to delta-9-tetrahydrocannabinol causes enduring cognitive deficits associated with alteration of cortical gene expression and neurotransmission in rats. Addiction Biology. 12: 485-95. PMID 17578508 DOI: 10.1111/J.1369-1600.2007.00074.X  0.306
2007 Hansson AC, Cippitelli A, Sommer WH, Ciccocioppo R, Heilig M. Region-specific down-regulation of Crhr1 gene expression in alcohol-preferring msP rats following ad lib access to alcohol. Addiction Biology. 12: 30-4. PMID 17407495 DOI: 10.1111/J.1369-1600.2007.00050.X  0.641
2007 Gehlert DR, Cippitelli A, Thorsell A, Lê AD, Hipskind PA, Hamdouchi C, Lu J, Hembre EJ, Cramer J, Song M, McKinzie D, Morin M, Ciccocioppo R, Heilig M. 3-(4-Chloro-2-morpholin-4-yl-thiazol-5-yl)-8-(1-ethylpropyl)-2,6-dimethyl-imidazo[1,2-b]pyridazine: a novel brain-penetrant, orally available corticotropin-releasing factor receptor 1 antagonist with efficacy in animal models of alcoholism. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 2718-26. PMID 17344409 DOI: 10.1523/Jneurosci.4985-06.2007  0.667
2007 Rizzi A, Gavioli EC, Marzola G, Spagnolo B, Zucchini S, Ciccocioppo R, Trapella C, Regoli D, Calò G. Pharmacological characterization of the nociceptin/orphanin FQ receptor antagonist SB-612111 [(-)-cis-1-methyl-7-[[4-(2,6-dichlorophenyl)piperidin-1-yl]methyl]-6,7,8,9-tetrahydro-5H-benzocyclohepten-5-ol]: in vivo studies. The Journal of Pharmacology and Experimental Therapeutics. 321: 968-74. PMID 17329551 DOI: 10.1124/Jpet.106.116780  0.374
2007 Ciccocioppo R, Economidou D, Rimondini R, Sommer W, Massi M, Heilig M. Buprenorphine reduces alcohol drinking through activation of the nociceptin/orphanin FQ-NOP receptor system. Biological Psychiatry. 61: 4-12. PMID 16533497 DOI: 10.1016/J.Biopsych.2006.01.006  0.677
2007 Ciccocioppo R, Heilig M. Reply Biological Psychiatry. 62: 702. DOI: 10.1016/j.biopsych.2007.02.013  0.314
2007 Massi M, Fedeli A, Economidou D, Braconi S, Cippitelli A, Ciccocioppo R. Interactions between neuropeptide S and corticotropin releasing factor in the control of palatable food intake in rats. Appetite. 49: 311. DOI: 10.1016/J.Appet.2007.03.131  0.336
2006 Economidou D, Fedeli A, Fardon RM, Weiss F, Massi M, Ciccocioppo R. Effect of novel nociceptin/orphanin FQ-NOP receptor ligands on ethanol drinking in alcohol-preferring msP rats. Peptides. 27: 3299-306. PMID 17097763 DOI: 10.1016/J.Peptides.2006.09.007  0.729
2006 Fedeli A, Policani F, Ubaldi M, Cippitelli A, Massi M, Ciccocioppo R. Activation of the nociceptin/orphanin FQ system is unable to reverse CRF2 receptor mediated anorexia in the rat. Peptides. 27: 3284-91. PMID 17050037 DOI: 10.1016/J.Peptides.2006.09.001  0.401
2006 Hansson AC, Cippitelli A, Sommer WH, Fedeli A, Björk K, Soverchia L, Terasmaa A, Massi M, Heilig M, Ciccocioppo R. Variation at the rat Crhr1 locus and sensitivity to relapse into alcohol seeking induced by environmental stress. Proceedings of the National Academy of Sciences of the United States of America. 103: 15236-41. PMID 17015825 DOI: 10.1073/Pnas.0604419103  0.654
2006 Ciccocioppo R, Economidou D, Cippitelli A, Cucculelli M, Ubaldi M, Soverchia L, Lourdusamy A, Massi M. Genetically selected Marchigian Sardinian alcohol-preferring (msP) rats: an animal model to study the neurobiology of alcoholism. Addiction Biology. 11: 339-55. PMID 16961763 DOI: 10.1111/J.1369-1600.2006.00032.X  0.558
2006 Ciccocioppo R, Hyytia P. The genetic of alcoholism: learning from 50 years of research. Addiction Biology. 11: 193-4. PMID 16961757 DOI: 10.1111/J.1369-1600.2006.00028.X  0.354
2006 Economidou D, Policani F, Angellotti T, Massi M, Terada T, Ciccocioppo R. Effect of novel NOP receptor ligands on food intake in rats. Peptides. 27: 775-83. PMID 16483692 DOI: 10.1016/J.Peptides.2005.08.014  0.408
2006 Economidou D, Mattioli L, Cifani C, Perfumi M, Massi M, Cuomo V, Trabace L, Ciccocioppo R. Effect of the cannabinoid CB1 receptor antagonist SR-141716A on ethanol self-administration and ethanol-seeking behaviour in rats. Psychopharmacology. 183: 394-403. PMID 16261315 DOI: 10.1007/S00213-005-0199-9  0.506
2005 Perfumi M, Mattioli L, Forti L, Massi M, Ciccocioppo R. Effect of Hypericum perforatum CO2 extract on the motivational properties of ethanol in alcohol-preferring rats. Alcohol and Alcoholism (Oxford, Oxfordshire). 40: 291-6. PMID 15870093 DOI: 10.1093/Alcalc/Agh133  0.48
2005 Cippitelli A, Bilbao A, Hansson AC, del Arco I, Sommer W, Heilig M, Massi M, Bermúdez-Silva FJ, Navarro M, Ciccocioppo R, de Fonseca FR. Cannabinoid CB1 receptor antagonism reduces conditioned reinstatement of ethanol-seeking behavior in rats. The European Journal of Neuroscience. 21: 2243-51. PMID 15869521 DOI: 10.1111/J.1460-9568.2005.04056.X  0.695
2005 Bachteler D, Economidou D, Danysz W, Ciccocioppo R, Spanagel R. The effects of acamprosate and neramexane on cue-induced reinstatement of ethanol-seeking behavior in rat. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 30: 1104-10. PMID 15668725 DOI: 10.1038/Sj.Npp.1300657  0.497
2005 Cippitelli A, Soverchia L, Massi M, Ciccocioppo R. A131 Footshock Stress-Induced Alcohol Relapse: Comparison Between Genetically Selected Alcohol-Preferring Rats And Nonselected Wistars Behavioural Pharmacology. 16. DOI: 10.1097/00008877-200509001-00204  0.481
2005 Economidou D, Maurizio M, Ciccocioppo R. O8 LONG-LASTING RELAPSE VULNERABILITY BY STIMULI PREDICTIVE OF ALCOHOL AVAILABILITY IS INDEPENDENT OF ITS REINFORCING VALUE Behavioural Pharmacology. 16: S20-S21. DOI: 10.1097/00008877-200509001-00065  0.363
2004 Ciccocioppo R, Cippitelli A, Economidou D, Fedeli A, Massi M. Nociceptin/orphanin FQ acts as a functional antagonist of corticotropin-releasing factor to inhibit its anorectic effect. Physiology & Behavior. 82: 63-8. PMID 15234592 DOI: 10.1016/J.Physbeh.2004.04.035  0.39
2004 Ciccocioppo R, Martin-Fardon R, Weiss F. Stimuli associated with a single cocaine experience elicit long-lasting cocaine-seeking. Nature Neuroscience. 7: 495-6. PMID 15048121 DOI: 10.1038/Nn1219  0.607
2004 Ciccocioppo R, Economidou D, Fedeli A, Angeletti S, Weiss F, Heilig M, Massi M. Attenuation of ethanol self-administration and of conditioned reinstatement of alcohol-seeking behaviour by the antiopioid peptide nociceptin/orphanin FQ in alcohol-preferring rats. Psychopharmacology. 172: 170-8. PMID 14624331 DOI: 10.1007/S00213-003-1645-1  0.822
2004 Fedeli A, Policani F, Economidou D, Ciccocioppo R, Massi M. P25 FOOD INTAKE INHIBITION BY SELECTIVE CRF2 RECEPTORS STIMULATION IS BLOCKED BY THE NOCICEPTIN/ORPHANIN FQ ANALOGUE RO 64???6198 Behavioural Pharmacology. 15: A15. DOI: 10.1097/00008877-200409000-00065  0.313
2004 Economidou D, Fedeli A, Cippitelli A, Ubaldi M, Massi M, Ciccocioppo R. P23 GENETIC FACTORS, BUT NOT THE REINFORCING PROPERTIES OF ETHANOL, INFLUENCE CONDITIONED REINSTATEMENT OF ALCOHOL-SEEKING IN RATS Behavioural Pharmacology. 15: A15. DOI: 10.1097/00008877-200409000-00063  0.494
2004 Ciccocioppo R, Cippitelli A, Soverchia L, Ubaldi M, Heilig M, Sommer W, Arlinde C, Hansson A, Hyytia P, Fonseca Fd, Massi M. P13 FUNCTIONAL GENOMICS FOR TARGET GENE IDENTIFICATION IN ANIMAL MODELS OF ALCOHOL ABUSE: THE ROLE OF THE CANNABINOID CB1 RECEPTOR SYSTEM Behavioural Pharmacology. 15: A11-A12. DOI: 10.1097/00008877-200409000-00053  0.576
2004 Ciccocioppo R, Massi M. THE NOCICEPTIN/ORPHANIN FQ-NOP RECEPTOR SYSTEM: A POTENTIAL TARGET FOR TREATMENT OF ALCOHOL ADDICTION. Alcoholism: Clinical & Experimental Research. 28: 57A. DOI: 10.1097/00000374-200408002-00304  0.353
2004 Fedeli A, Hansson A, Heilig M, Economidou D, Massi M, Ciccocioppo R. THE NOCICEPTIN/ORPHANIN FQ SYSTEM IS DIFFERENTIALLY REGULATED IN GENETICALLY SELECTED ALCOHOL PREFERRING MSP COMPARED TO WISTAR RATS. Alcoholism: Clinical & Experimental Research. 28: 17A. DOI: 10.1097/00000374-200408002-00064  0.616
2004 Mattioli L, Economidou D, Perfumi M, Ciccocioppo R, Massi M. THE CB1 RECEPTOR ANTAGONIST SR-141716 REDUCES VULNERABILITY TO ETHANOL ABUSE: EFFECT OF PERINATAL EXPOSURE TO THC AND ALCOHOL. Alcoholism: Clinical & Experimental Research. 28: 17A. DOI: 10.1097/00000374-200408002-00063  0.51
2004 Bachteler D, Economidou D, Ciccocioppo R, Spanagel R. ACAMPROSATE, BUT NOT NERAMEXANE, REDUCES CUE-INDUCED REINSTATEMENT OF ETHANOL-SEEKING BEHAVIOR. Alcoholism: Clinical & Experimental Research. 28: 15A. DOI: 10.1097/00000374-200408002-00052  0.379
2003 Perfumi M, Santoni M, Cippitelli A, Ciccocioppo R, Froldi R, Massi M. Hypericum perforatum CO2 extract and opioid receptor antagonists act synergistically to reduce ethanol intake in alcohol-preferring rats. Alcoholism, Clinical and Experimental Research. 27: 1554-62. PMID 14574225 DOI: 10.1097/01.Alc.0000092062.60924.56  0.475
2003 Ciccocioppo R, Fedeli A, Economidou D, Policani F, Weiss F, Massi M. The bed nucleus is a neuroanatomical substrate for the anorectic effect of corticotropin-releasing factor and for its reversal by nociceptin/orphanin FQ. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 9445-51. PMID 14561874 DOI: 10.1523/Jneurosci.23-28-09445.2003  0.639
2003 Ciccocioppo R, Economidou D, Fedeli A, Massi M. The nociceptin/orphanin FQ/NOP receptor system as a target for treatment of alcohol abuse: a review of recent work in alcohol-preferring rats. Physiology & Behavior. 79: 121-8. PMID 12818717 DOI: 10.1016/S0031-9384(03)00112-4  0.576
2003 Ciccocioppo R, Lin D, Martin-Fardon R, Weiss F. Reinstatement of ethanol-seeking behavior by drug cues following single versus multiple ethanol intoxication in the rat: effects of naltrexone. Psychopharmacology. 168: 208-15. PMID 12664190 DOI: 10.1007/S00213-002-1380-Z  0.667
2003 Koob GF, Roberts AJ, Kieffer BL, Heyser CJ, Katner SN, Ciccocioppo R, Weiss F. Animal models of motivation for drinking in rodents with a focus on opioid receptor neuropharmacology. Recent Developments in Alcoholism : An Official Publication of the American Medical Society On Alcoholism, the Research Society On Alcoholism, and the National Council On Alcoholism. 16: 263-81. PMID 12638642  0.811
2002 Fedeli A, Ciccocioppo R, Economidou D, Angeletti S, Massi M. Autoradiographic analysis of 5-hydroxytryptamine 5-HT2A binding sites in the rat brain after chronic intragastric ethanol treatments. Research Communications in Molecular Pathology and Pharmacology. 112: 113-27. PMID 15080502  0.649
2002 Perfumi M, Santoni M, Ciccocioppo R, Massi M. Blockade of gamma-aminobutyric acid receptors does not modify the inhibiton of ethanol intake induced by Hypericum perforatum in rats. Alcohol and Alcoholism (Oxford, Oxfordshire). 37: 540-6. PMID 12414544 DOI: 10.1093/Alcalc/37.6.540  0.431
2002 Ciccocioppo R, Martin-Fardon R, Weiss F. Effect of selective blockade of mu(1) or delta opioid receptors on reinstatement of alcohol-seeking behavior by drug-associated stimuli in rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 27: 391-9. PMID 12225696 DOI: 10.1016/S0893-133X(02)00302-0  0.702
2002 Ciccocioppo R, Antonelli L, Biondini M, Perfumi M, Pompei P, Massi M. Memory impairment following combined exposure to delta(9)-tetrahydrocannabinol and ethanol in rats. European Journal of Pharmacology. 449: 245-52. PMID 12167466 DOI: 10.1016/S0014-2999(02)01999-4  0.446
2002 Rizzi A, Salis MB, Ciccocioppo R, Marzola G, Bigoni R, Guerrini R, Massi M, Madeddu P, Salvadori S, Regoli D, Calo' G. Pharmacological characterisation of [(pX)Phe4]nociceptin(1-13)NH2 analogues. 2. In vivo studies. Naunyn-Schmiedeberg's Archives of Pharmacology. 365: 450-6. PMID 12070758 DOI: 10.1007/S00210-002-0549-7  0.341
2002 Ciccocioppo R, Biondini M, Antonelli L, Wichmann J, Jenck F, Massi M. Reversal of stress- and CRF-induced anorexia in rats by the synthetic nociceptin/orphanin FQ receptor agonist, Ro 64-6198. Psychopharmacology. 161: 113-9. PMID 11981590 DOI: 10.1007/S00213-002-1020-7  0.432
2002 Ciccocioppo R, Polidori C, Antonelli L, Salvadori S, Guerrini R, Massi M. Pharmacological characterization of the nociceptin receptor which mediates reduction of alcohol drinking in rats. Peptides. 23: 117-25. PMID 11814626 DOI: 10.1016/S0196-9781(01)00587-3  0.547
2001 Ciccocioppo R, Angeletti S, Weiss F. Long-lasting resistance to extinction of response reinstatement induced by ethanol-related stimuli: role of genetic ethanol preference. Alcoholism, Clinical and Experimental Research. 25: 1414-9. PMID 11696659 DOI: 10.1111/J.1530-0277.2001.Tb02141.X  0.762
2001 Weiss F, Martin-Fardon R, Ciccocioppo R, Kerr TM, Smith DL, Ben-Shahar O. Enduring resistance to extinction of cocaine-seeking behavior induced by drug-related cues. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 25: 361-72. PMID 11522464 DOI: 10.1016/S0893-133X(01)00238-X  0.74
2001 Weiss F, Ciccocioppo R, Parsons LH, Katner S, Liu X, Zorrilla EP, Valdez GR, Ben-Shahar O, Angeletti S, Richter RR. Compulsive drug-seeking behavior and relapse. Neuroadaptation, stress, and conditioning factors. Annals of the New York Academy of Sciences. 937: 1-26. PMID 11458532 DOI: 10.1111/J.1749-6632.2001.Tb03556.X  0.805
2001 Perfumi M, Panocka I, Ciccocioppo R, Vitali D, Froldi R, Massi M. Effects of a methanolic extract and a hyperforin-enriched CO2 extract of Hypericum perforatum on alcohol intake in rats. Alcohol and Alcoholism (Oxford, Oxfordshire). 36: 199-206. PMID 11373255 DOI: 10.1093/Alcalc/36.3.199  0.457
2001 Ciccocioppo R, Martin-Fardon R, Weiss F, Massi M. Nociceptin/orphanin FQ inhibits stress- and CRF-induced anorexia in rats. Neuroreport. 12: 1145-9. PMID 11338181 DOI: 10.1097/00001756-200105080-00019  0.65
2001 Ciccocioppo R, Sanna PP, Weiss F. Cocaine-predictive stimulus induces drug-seeking behavior and neural activation in limbic brain regions after multiple months of abstinence: reversal by D(1) antagonists. Proceedings of the National Academy of Sciences of the United States of America. 98: 1976-81. PMID 11172061 DOI: 10.1073/Pnas.98.4.1976  0.616
2000 Ciccocioppo R, Angeletti S, Panocka I, Massi M. Nociceptin/orphanin FQ and drugs of abuse. Peptides. 21: 1071-80. PMID 10998542 DOI: 10.1016/S0196-9781(00)00245-X  0.718
2000 Ciccocioppo R, Angeletti S, Sanna PP, Weiss F, Massi M. Effect of nociceptin/orphanin FQ on the rewarding properties of morphine. European Journal of Pharmacology. 404: 153-9. PMID 10980274 DOI: 10.1016/S0014-2999(00)00590-2  0.731
2000 Polidori C, Calo G, Ciccocioppo R, Guerrini R, Regoli D, Massi M. Pharmacological characterization of the nociceptin receptor mediating hyperphagia: identification of a selective antagonist. Psychopharmacology. 148: 430-7. PMID 10928317 DOI: 10.1007/S002130050073  0.407
2000 Martin-Fardon R, Ciccocioppo R, Massi M, Weiss F. Nociceptin prevents stress-induced ethanol- but not cocaine-seeking behavior in rats. Neuroreport. 11: 1939-43. PMID 10884047 DOI: 10.1097/00001756-200006260-00026  0.694
2000 Panocka I, Perfumi M, Angeletti S, Ciccocioppo R, Massi M. Effects of Hypericum perforatum extract on ethanol intake, and on behavioral despair: a search for the neurochemical systems involved. Pharmacology, Biochemistry, and Behavior. 66: 105-11. PMID 10837849 DOI: 10.1016/S0091-3057(00)00193-3  0.686
2000 Polidori C, Ciccocioppo R, Regoli D, Massi M. Neuropeptide Y receptor(s) mediating feeding in the rat: characterization with antagonists. Peptides. 21: 29-35. PMID 10704716 DOI: 10.1016/S0196-9781(99)00170-9  0.405
2000 Panocka I, Perfumi M, Angeletti S, Ciccocioppo R, Massi M. Effects of Hypericum perforatum extract on ethanol intake, and on behavioral despair - A search for the neurochemical systems involved Pharmacology Biochemistry and Behavior. 66: 105-111. DOI: 10.1016/S0091-3057(00)00193-3  0.568
1999 Ciccocioppo R, Angeletti S, Chhada M, Perfumi M, Froldi R, Massi M. Conditioned taste aversion induced by ethanol in alcohol-preferring rats: influence of the method of ethanol administration. Pharmacology, Biochemistry, and Behavior. 64: 563-6. PMID 10548272 DOI: 10.1016/S0091-3057(99)00104-5  0.688
1999 Perfumi M, Ciccocioppo R, Angeletti S, Cucculelli M, Massi M. Effects of Hypericum perforatum extraction on alcohol intake in Marchigian Sardinian alcohol-preferring rats. Alcohol and Alcoholism (Oxford, Oxfordshire). 34: 690-8. PMID 10528811 DOI: 10.1093/Alcalc/34.5.690  0.691
1999 Ciccocioppo R, Angeletti S, Colombo G, Gessa G, Massi M. Autoradiographic analysis of 5-HT2A binding sites in the brain of Sardinian alcohol-preferring and nonpreferring rats. European Journal of Pharmacology. 373: 13-9. PMID 10408247 DOI: 10.1016/S0014-2999(99)00239-3  0.618
1999 Ciccocioppo R, Panocka I, Froldi R, Colombo G, Gessa GL, Massi M. Antidepressant-like effect of ethanol revealed in the forced swimming test in Sardinian alcohol-preferring rats. Psychopharmacology. 144: 151-7. PMID 10394996 DOI: 10.1007/S002130050988  0.502
1999 Ciccocioppo R, Panocka I, Froldi R, Quitadamo E, Massi M. Ethanol induces conditioned place preference in genetically selected alcohol-preferring rats. Psychopharmacology. 141: 235-41. PMID 10027504 DOI: 10.1007/S002130050830  0.487
1999 Ciccocioppo R, Panocka I, Polidori C, Regoli D, Massi M. Effect of nociceptin on alcohol intake in alcohol-preferring rats. Psychopharmacology. 141: 220-4. PMID 9952048 DOI: 10.1007/S002130050828  0.509
1998 Polidori C, Recchi S, Venturi F, Ciccocioppo R, Massi M. Application of taste reactivity to study the mechanism of alcohol intake inhibition by the tachykinin aminosenktide. Peptides. 19: 1557-64. PMID 9864063 DOI: 10.1016/S0196-9781(98)00112-0  0.538
1998 Ciccocioppo R, Panocka I, Polidori C, Froldi R, Angeletti S, Massi M. Mechanism of action for reduction of ethanol intake in rats by the tachykinin NK-3 receptor agonist aminosenktide. Pharmacology, Biochemistry, and Behavior. 61: 459-64. PMID 9802842 DOI: 10.1016/S0091-3057(98)00090-2  0.723
1998 Polidori C, Ciccocioppo R, Nisato D, Cazaubon C, Massi M. Evaluation of the ability of irbesartan to cross the blood-brain barrier following acute intragastric treatment. European Journal of Pharmacology. 352: 15-21. PMID 9718262 DOI: 10.1016/S0014-2999(98)00329-X  0.354
1998 Ciccocioppo R, Ge J, Barnes NM, Cooper SJ. Central 5-HT3 receptors in P and in AA alcohol-preferring rats: An autoradiographic study. Brain Research Bulletin. 46: 311-5. PMID 9671260 DOI: 10.1016/S0361-9230(98)00016-1  0.463
1998 Panocka I, Ciccocioppo R, Polidori C, Angeletti S, De Caro G, Massi M. Sensitivity of brain sites to the inhibitory effect on alcohol intake of the tachykinin aminosenktide. Peptides. 19: 897-905. PMID 9663456 DOI: 10.1016/S0196-9781(98)00038-2  0.696
1998 Pompei P, Angeletti S, Ciccocioppo R, Colombo G, Gessa GL, Massi M. Preprotachykinin-A gene expression in the forebrain of Sardinian alcohol-preferring and -nonpreferring rats. Brain Research. Molecular Brain Research. 56: 277-80. PMID 9602150 DOI: 10.1016/S0169-328X(98)00043-6  0.685
1998 Polidori C, Ciccocioppo R, De Caro G, Massi M. Further evidence that central tachykinin NK-1 receptors mediate the inhibitory effect of tachykinins on angiotensin-induced drinking in rats. Peptides. 19: 149-55. PMID 9437747 DOI: 10.1016/S0196-9781(97)00252-0  0.44
1997 Ciccocioppo R, Panocka I, Polidori C, Dourish CT, Massi M. Blockade of pre- and post-synaptic 5-HT1A receptors does not modify the effect of fluoxetine or 5-hydroxytryptophan on ethanol and food intake in rats. Psychopharmacology. 134: 55-63. PMID 9399367 DOI: 10.1007/S002130050425  0.42
1997 Ciccocioppo R, Panocka I, Polidori C, De Caro G, Regoli D, Massi M. Stimulation of tachykinin NK-3 receptors in the nucleus basalis magnocellularis reduces alcohol intake in rats. Peptides. 18: 1349-55. PMID 9392836 DOI: 10.1016/S0196-9781(97)00189-7  0.532
1997 Ciccocioppo R, Ge J, Barnes NM, Cooper SJ. Autoradiographic mapping of brain 5-HT2A binding sites in P and in AA alcohol-preferring rats. Brain Research Bulletin. 44: 33-7. PMID 9288829 DOI: 10.1016/S0361-9230(96)00379-6  0.409
1997 Polidori C, Panocka I, Ciccocioppo R, Broccardo M, Improta G, Regoli D, Massi M. Further evidence that the tachykinin PG-KII is a potent agonist at central NK-3, but not NK-1, receptors. Peptides. 18: 825-33. PMID 9285931 DOI: 10.1016/S0196-9781(97)00022-3  0.473
1997 Pompei P, Angeletti S, Polidori C, Ciccocioppo R, De Caro G, Massi M. Regulation of preprotachykinin-A mRNA in genetic hypertensive and normotensive rats. Brain Research. Molecular Brain Research. 47: 78-86. PMID 9221904 DOI: 10.1016/S0169-328X(97)00053-3  0.6
1996 Panocka I, Ciccocioppo R, Polidori C, Romagnoli S, Froldi R, Massi M. Possible mechanism of action for the attenuation of ethanol intake induced by ritanserin in rats. Psychopharmacology. 128: 181-90. PMID 8956379 DOI: 10.1007/S002130050123  0.445
1996 Polidori C, Pompei P, Ciccocioppo R, de Caro G, Massi M. Effects of the selective tachykinin NK3 receptor agonist NH2-senktide on intraoral intake and taste reactivity responses elicited by NaCl in sodium-replete rats. Regulatory Peptides. 66: 101-4. PMID 8899901 DOI: 10.1016/0167-0115(96)00057-2  0.365
1995 Panocka I, Ciccocioppo R, Polidori C, Pompei P, Massi M. The 5-HT4 receptor antagonist, GR113808, reduces ethanol intake in alcohol-preferring rats. Pharmacology, Biochemistry, and Behavior. 52: 255-9. PMID 8577787 DOI: 10.1016/0091-3057(95)00078-B  0.49
1995 Ciccocioppo R, Panocka I, Pompei P, Polidori C, de Caro G, Massi M. Subcutaneous injections of the tachykinin senktide reduce alcohol intake in alcohol-preferring rats. Peptides. 16: 533-7. PMID 7544465 DOI: 10.1016/0196-9781(94)00219-V  0.487
1995 Ciccocioppo R, Panocka I, Stefanini E, Gessa GL, Massi M. Low responsiveness to agents evoking 5-HT2 receptor-mediated behaviors in Sardinian alcohol-preferring rats. Pharmacology, Biochemistry, and Behavior. 51: 21-7. PMID 7542392 DOI: 10.1016/0091-3057(94)00322-A  0.428
1995 Polidori C, Ciccocioppo R, Pompei P, Cirillo R, Massi M. The selective angiotensin AT1 receptor antagonist LR-B/081 potently inhibits drinking induced by central injection of angiotensin II in rats. European Journal of Pharmacology. 277: 223-8. PMID 7493612 DOI: 10.1016/0014-2999(95)00079-Z  0.397
1995 Panocka I, Ciccocioppo R, Mosca M, Polidori C, Massi M. Effects of the dopamine D1 receptor antagonist SCH 39166 on the ingestive behaviour of alcohol-preferring rats. Psychopharmacology. 120: 227-35. PMID 7480557 DOI: 10.1007/Bf02246198  0.474
1995 Massi M, Panocka I, Ciccocioppo R, Polidori C, Pompei P. Further evidence that 5-HT4 receptor antagonists suppress alcohol intake in rats Pharmacological Research. 31: 35. DOI: 10.1016/1043-6618(95)86400-8  0.462
1994 Ciccocioppo R, Polidori C, Pompei P, de Caro G, Massi M. Inhibition of isotonic sodium chloride intake in the rat by selective tachykinin agonists. Pharmacology, Biochemistry, and Behavior. 47: 609-15. PMID 8208781 DOI: 10.1016/0091-3057(94)90166-X  0.395
1994 Polidori C, Ciccocioppo R, Epstein AN, de Caro G, Massi M. Effect of tachykinins on the need-free sodium intake of female rats: a continuous intracerebroventricular infusion study. Physiology & Behavior. 56: 877-82. PMID 7529926 DOI: 10.1016/0031-9384(94)90318-2  0.355
1994 Ciccocioppo R, Panocka I, Pompei P, De Caro G, Massi M. Selective agonists at NK3 tachykinin receptors inhibit alcohol intake in Sardinian alcohol-preferring rats. Brain Research Bulletin. 33: 71-7. PMID 7506113 DOI: 10.1016/0361-9230(94)90050-7  0.516
1993 Panocka I, Ciccocioppo R, Polidori C, Massi M. The nucleus accumbens is a site of action for the inhibitory effect of ritanserin on ethanol intake in rats. Pharmacology, Biochemistry, and Behavior. 46: 857-62. PMID 8309966 DOI: 10.1016/0091-3057(93)90213-D  0.45
1993 Panocka I, Ciccocioppo R, Pompei P, Massi M. 5-HT2 receptor antagonists do not reduce ethanol preference in Sardinian alcohol-preferring (sP) rats. Pharmacology, Biochemistry, and Behavior. 46: 853-6. PMID 7508629 DOI: 10.1016/0091-3057(93)90212-C  0.456
1992 Ciccocioppo R, Pompei P, Polidori C, Massi M, de Caro G. Inhibitory effect of the NK-3 selective agonist NH2-Senktide on the need-free salt intake of the rat Neuropeptides. 22: 14. DOI: 10.1016/0143-4179(92)90374-6  0.367
1991 Massi M, Polidori C, Perfumi M, Ciccocioppo R, De Caro G, Bacciarelli C, Manzini S. Effect of capsaicin neonatal treatment on the salt intake of the adult rat. Pharmacology, Biochemistry, and Behavior. 40: 163-8. PMID 1685783 DOI: 10.1016/0091-3057(91)90338-3  0.373
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