Eric M. Tam, Ph.D. - Publications

Affiliations: 
2005 University of British Columbia, Vancouver, Vancouver, BC, Canada 
Area:
Molecular Biology

12 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2009 Tam EM, Runyon ST, Santell L, Quan C, Yao X, Kirchhofer D, Skelton NJ, Lazarus RA. Noncompetitive inhibition of hepatocyte growth factor-dependent Met signaling by a phage-derived peptide. Journal of Molecular Biology. 385: 79-90. PMID 18973760 DOI: 10.1016/J.Jmb.2008.09.091  0.333
2008 Butler GS, Dean RA, Tam EM, Overall CM. Pharmacoproteomics of a metalloproteinase hydroxamate inhibitor in breast cancer cells: dynamics of membrane type 1 matrix metalloproteinase-mediated membrane protein shedding. Molecular and Cellular Biology. 28: 4896-914. PMID 18505826 DOI: 10.1128/Mcb.01775-07  0.706
2007 Wolf K, Wu YI, Liu Y, Geiger J, Tam E, Overall C, Stack MS, Friedl P. Multi-step pericellular proteolysis controls the transition from individual to collective cancer cell invasion. Nature Cell Biology. 9: 893-904. PMID 17618273 DOI: 10.1038/Ncb1616  0.677
2007 Iida J, Wilhelmson KL, Ng J, Lee P, Morrison C, Tam E, Overall CM, McCarthy JB. Cell surface chondroitin sulfate glycosaminoglycan in melanoma: role in the activation of pro-MMP-2 (pro-gelatinase A). The Biochemical Journal. 403: 553-63. PMID 17217338 DOI: 10.1042/Bj20061176  0.736
2004 Tam EM, Moore TR, Butler GS, Overall CM. Characterization of the distinct collagen binding, helicase and cleavage mechanisms of matrix metalloproteinase 2 and 14 (gelatinase A and MT1-MMP): the differential roles of the MMP hemopexin c domains and the MMP-2 fibronectin type II modules in collagen triple helicase activities. The Journal of Biological Chemistry. 279: 43336-44. PMID 15292230 DOI: 10.1074/Jbc.M407186200  0.737
2004 Overall CM, Tam EM, Kappelhoff R, Connor A, Ewart T, Morrison CJ, Puente X, López-Otín C, Seth A. Protease degradomics: mass spectrometry discovery of protease substrates and the CLIP-CHIP, a dedicated DNA microarray of all human proteases and inhibitors. Biological Chemistry. 385: 493-504. PMID 15255181 DOI: 10.1515/Bc.2004.058  0.702
2004 Tam EM, Morrison CJ, Wu YI, Stack MS, Overall CM. Membrane protease proteomics: Isotope-coded affinity tag MS identification of undescribed MT1-matrix metalloproteinase substrates. Proceedings of the National Academy of Sciences of the United States of America. 101: 6917-22. PMID 15118097 DOI: 10.1073/Pnas.0305862101  0.72
2004 Butler GS, Tam EM, Overall CM. The canonical methionine 392 of matrix metalloproteinase 2 (gelatinase A) is not required for catalytic efficiency or structural integrity: probing the role of the methionine-turn in the metzincin metalloprotease superfamily. The Journal of Biological Chemistry. 279: 15615-20. PMID 14732714 DOI: 10.1074/Jbc.M312727200  0.719
2002 Tam EM, Wu YI, Butler GS, Stack MS, Overall CM. Collagen binding properties of the membrane type-1 matrix metalloproteinase (MT1-MMP) hemopexin C domain. The ectodomain of the 44-kDa autocatalytic product of MT1-MMP inhibits cell invasion by disrupting native type I collagen cleavage. The Journal of Biological Chemistry. 277: 39005-14. PMID 12145314 DOI: 10.1074/Jbc.M206874200  0.737
2002 Butler GS, Sim D, Tam E, Devine D, Overall CM. Mannose-binding lectin (MBL) mutants are susceptible to matrix metalloproteinase proteolysis: potential role in human MBL deficiency. The Journal of Biological Chemistry. 277: 17511-9. PMID 11891230 DOI: 10.1074/Jbc.M201461200  0.73
2000 McQuibban GA, Gong JH, Tam EM, McCulloch CA, Clark-Lewis I, Overall CM. Inflammation dampened by gelatinase A cleavage of monocyte chemoattractant protein-3. Science (New York, N.Y.). 289: 1202-6. PMID 10947989 DOI: 10.1126/Science.289.5482.1202  0.643
1999 Overall CM, King AE, Bigg HF, McQuibban A, Atherstone J, Sam DK, Ong AD, Lau TT, Wallon UM, DeClerck YA, Tam E. Identification of the TIMP-2 binding site on the gelatinase A hemopexin C-domain by site-directed mutagenesis and the yeast two-hybrid system. Annals of the New York Academy of Sciences. 878: 747-53. PMID 10415826 DOI: 10.1111/J.1749-6632.1999.Tb07780.X  0.538
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