Year |
Citation |
Score |
2024 |
Thompson AJ, Wu NC, Canales A, Kikuchi C, Zhu X, de Toro BF, Cañada FJ, Worth C, Wang S, McBride R, Peng W, Nycholat CM, Jiménez-Barbero J, Wilson IA, Paulson JC. Evolution of human H3N2 influenza virus receptor specificity has substantially expanded the receptor-binding domain site. Cell Host & Microbe. PMID 38307019 DOI: 10.1016/j.chom.2024.01.003 |
0.35 |
|
2023 |
Canales A, Sastre J, Orduña JM, Spruit CM, Pérez-Castells J, Domínguez G, Bouwman KM, van der Woude R, Cañada FJ, Nycholat CM, Paulson JC, Boons GJ, Jiménez-Barbero J, de Vries RP. Revealing the Specificity of Human H1 Influenza A Viruses to Complex -Glycans. Jacs Au. 3: 868-878. PMID 37006776 DOI: 10.1021/jacsau.2c00664 |
0.708 |
|
2022 |
Lenza MP, Atxabal U, Nycholat C, Oyenarte I, Franconetti A, Quintana JI, Delgado S, Núñez-Franco R, Garnica Marroquín CT, Coelho H, Unione L, Jiménez-Oses G, Marcelo F, Schubert M, Paulson JC, et al. Structures of the Inhibitory Receptor Siglec-8 in Complex with a High-Affinity Sialoside Analogue and a Therapeutic Antibody. Jacs Au. 3: 204-215. PMID 36711084 DOI: 10.1021/jacsau.2c00592 |
0.522 |
|
2022 |
Hardy LC, Smeekens J, Raghuwanshi D, Sarkar S, Daskhan GC, Rogers S, Nycholat C, Maleki S, Burks AW, Paulson JC, Macauley MS, Kulis MD. Targeting CD22 on Memory B Cells to Induce Tolerance to Peanut Allergens. The Journal of Allergy and Clinical Immunology. PMID 35839842 DOI: 10.1016/j.jaci.2022.06.022 |
0.439 |
|
2022 |
Harumoto T, Iwai H, Tanigawa M, Kubo T, Atsumi T, Tsutsumi K, Takashima M, Destito G, Soloff R, Tomizuka K, Nycholat C, Paulson J, Uehara K. Enhancement of Gene Knockdown on CD22-Expressing Cells by Chemically Modified Glycan Ligand-siRNA Conjugates. Acs Chemical Biology. PMID 35020348 DOI: 10.1021/acschembio.1c00652 |
0.497 |
|
2021 |
Sojitra M, Sarkar S, Maghera J, Rodrigues E, Carpenter EJ, Seth S, Ferrer Vinals D, Bennett NJ, Reddy R, Khalil A, Xue X, Bell MR, Zheng RB, Zhang P, Nycholat C, et al. Genetically encoded multivalent liquid glycan array displayed on M13 bacteriophage. Nature Chemical Biology. PMID 33958792 DOI: 10.1038/s41589-021-00788-5 |
0.611 |
|
2021 |
Duan S, Arlian BM, Nycholat CM, Wei Y, Tateno H, Smith SA, Macauley MS, Zhu Z, Bochner BS, Paulson JC. Nanoparticles Displaying Allergen and Siglec-8 Ligands Suppress IgE-FcεRI-Mediated Anaphylaxis and Desensitize Mast Cells to Subsequent Antigen Challenge. Journal of Immunology (Baltimore, Md. : 1950). 206: 2290-2300. PMID 33911007 DOI: 10.4049/jimmunol.1901212 |
0.495 |
|
2021 |
Büll C, Nason R, Sun L, Van Coillie J, Madriz Sørensen D, Moons SJ, Yang Z, Arbitman S, Fernandes SM, Furukawa S, McBride R, Nycholat CM, Adema GJ, Paulson JC, Schnaar RL, et al. Probing the binding specificities of human Siglecs by cell-based glycan arrays. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33893239 DOI: 10.1073/pnas.2026102118 |
0.545 |
|
2020 |
Wu NC, Otwinowski J, Thompson AJ, Nycholat CM, Nourmohammad A, Wilson IA. Major antigenic site B of human influenza H3N2 viruses has an evolving local fitness landscape. Nature Communications. 11: 1233. PMID 32144244 DOI: 10.1038/S41467-020-15102-5 |
0.42 |
|
2019 |
Nycholat CM, Duan S, Knuplez E, Worth C, Elich M, Yao A, O'Sullivan J, McBride R, Wei Y, Fernandes SM, Zhu Z, Schnaar RL, Bochner BS, Paulson JC. A sulfonamide sialoside analog for targeting Siglec-8 and -F on im-mune cells. Journal of the American Chemical Society. PMID 31460762 DOI: 10.1021/Jacs.9B05769 |
0.558 |
|
2019 |
Wu NC, Lv H, Thompson AJ, Wu DC, Ng WWS, Kadam RU, Lin CW, Nycholat CM, McBride R, Liang W, Paulson JC, Mok CKP, Wilson IA. Preventing an Antigenically Disruptive Mutation in Egg-Based H3N2 Seasonal Influenza Vaccines by Mutational Incompatibility. Cell Host & Microbe. PMID 31151913 DOI: 10.1016/J.Chom.2019.04.013 |
0.529 |
|
2019 |
Bednar KJ, Nycholat CM, Rao TS, Paulson JC, Fung-Leung WP, Macauley MS. Exploiting CD22 to Selectively Tolerize Autoantibody Producing B-cells in Rheumatoid Arthritis. Acs Chemical Biology. PMID 30835424 DOI: 10.1021/Acschembio.8B01018 |
0.526 |
|
2019 |
Duan S, Koziol-White CJ, Jester WF, Nycholat CM, Macauley MS, Panettieri RA, Paulson JC. CD33 recruitment inhibits IgE-mediated anaphylaxis and desensitizes mast cells to allergen. The Journal of Clinical Investigation. PMID 30645205 DOI: 10.1172/Jci125456 |
0.565 |
|
2018 |
Edgar LJ, Kawasaki N, Nycholat CM, Paulson JC. Targeted Delivery of Antigen to Activated CD169 Macrophages Induces Bias for Expansion of CD8 T Cells. Cell Chemical Biology. PMID 30393066 DOI: 10.1016/J.Chembiol.2018.10.006 |
0.723 |
|
2018 |
Wu NC, Thompson AJ, Xie J, Lin CW, Nycholat CM, Zhu X, Lerner RA, Paulson JC, Wilson IA. A complex epistatic network limits the mutational reversibility in the influenza hemagglutinin receptor-binding site. Nature Communications. 9: 1264. PMID 29593268 DOI: 10.1038/S41467-018-03663-5 |
0.583 |
|
2018 |
Sun Y, Hong S, Xie R, Huang R, Lei R, Cheng B, Sun D, Du Y, Nycholat CM, Paulson JC, Chen X. Mechanistic Investigation and Multiplexing of Liposome-Assisted Metabolic Glycan Labeling. Journal of the American Chemical Society. PMID 29446631 DOI: 10.1021/Jacs.7B10990 |
0.525 |
|
2017 |
Spiller F, Nycholat CM, Kikuchi C, Paulson JC, Macauley MS. Murine Red Blood Cells Lack Ligands for B Cell Siglecs, Allowing Strong Activation by Erythrocyte Surface Antigens. Journal of Immunology (Baltimore, Md. : 1950). PMID 29288201 DOI: 10.4049/Jimmunol.1701257 |
0.552 |
|
2017 |
Wu NC, Zost SJ, Thompson AJ, Oyen D, Nycholat CM, McBride R, Paulson JC, Hensley SE, Wilson IA. A structural explanation for the low effectiveness of the seasonal influenza H3N2 vaccine. Plos Pathogens. 13: e1006682. PMID 29059230 DOI: 10.1371/Journal.Ppat.1006682 |
0.583 |
|
2017 |
Wu NC, Xie J, Zheng T, Nycholat CM, Grande G, Paulson JC, Lerner RA, Wilson IA. Diversity of Functionally Permissive Sequences in the Receptor-Binding Site of Influenza Hemagglutinin. Cell Host & Microbe. 22: 247-248. PMID 28799910 DOI: 10.1016/J.Chom.2017.07.001 |
0.55 |
|
2017 |
Wu NC, Xie J, Zheng T, Nycholat CM, Grande G, Paulson JC, Lerner RA, Wilson IA. Diversity of Functionally Permissive Sequences in the Receptor-Binding Site of Influenza Hemagglutinin. Cell Host & Microbe. 21: 742-753.e8. PMID 28618270 DOI: 10.1016/J.Chom.2017.05.011 |
0.59 |
|
2017 |
Tzarum N, McBride R, Nycholat CM, Paulson JC, Wilson IA. Unique structural features of influenza H15 HA. Journal of Virology. PMID 28404848 DOI: 10.1128/Jvi.00046-17 |
0.536 |
|
2017 |
Yu H, Gonzalez-Gil A, Wei Y, Fernandes SM, Porell RN, Vajn K, Paulson JC, Nycholat CM, Schnaar RL. Siglec-8 and Siglec-9 binding specificities and endogenous airway ligand distributions and properties. Glycobiology. PMID 28369504 DOI: 10.1093/Glycob/Cwx026 |
0.537 |
|
2017 |
Pang L, Macauley MS, Arlian BM, Nycholat CM, Paulson JC. Encapsulating An Immunosuppressant Enhances Tolerance Induction by Siglec Engaging Tolerogenic Liposomes. Chembiochem : a European Journal of Chemical Biology. PMID 28231415 DOI: 10.1002/Cbic.201600702 |
0.54 |
|
2017 |
Guo H, de Vries E, McBride R, Dekkers J, Bouwman KM, Nycholat C, Verheije MH, Paulson JC, van Kuppeveld FJ, de Haan CA. Highly Pathogenic Influenza A(H5Nx) Viruses with Altered H5 Receptor-Binding Specificity. Emerging Infectious Diseases. 23. PMID 27869615 DOI: 10.3201/Eid2302.161072 |
0.581 |
|
2017 |
Wu NC, Thompson AJ, Oyen D, Nycholat CM, McBride R, Paulson JC, Wilson IA. A structural explanation for the low efficacy of the seasonal influenza H3N2 vaccine Plos Pathogens. DOI: 10.2210/Pdb6Aop/Pdb |
0.514 |
|
2017 |
Paulson JC, Arlian B, Duan S, Macauley M, Nycholat CM, Pang L, Srivastava A. Harnessing Siglecs to Induce Immune Tolerance Transplantation. 101: S65. DOI: 10.1097/01.Tp.0000520400.15334.Ad |
0.462 |
|
2016 |
Sommer R, Wagner S, Varrot A, Nycholat CM, Khaledi A, Häussler S, Paulson JC, Imberty A, Titz A. The virulence factor LecB varies in clinical isolates: consequences for ligand binding and drug discovery. Chemical Science. 7: 4990-5001. PMID 30155149 DOI: 10.1039/C6Sc00696E |
0.552 |
|
2015 |
Angata T, Nycholat CM, Macauley MS. Therapeutic Targeting of Siglecs using Antibody- and Glycan-Based Approaches. Trends in Pharmacological Sciences. 36: 645-60. PMID 26435210 DOI: 10.1016/J.Tips.2015.06.008 |
0.358 |
|
2014 |
Bundle DR, Costello C, Nycholat C, Lipinski T, Rennie R. Designing a Candida albicans conjugate vaccine by reverse engineering protective monoclonal antibodies Anticarbohydrate Antibodies: From Molecular Basis to Clinical Application. 2147483647: 121-145. DOI: 10.1007/978-3-7091-0870-3_5 |
0.442 |
|
2013 |
Xu R, de Vries RP, Zhu X, Nycholat CM, McBride R, Yu W, Paulson JC, Wilson IA. Preferential recognition of avian-like receptors in human influenza A H7N9 viruses. Science (New York, N.Y.). 342: 1230-5. PMID 24311689 DOI: 10.1126/Science.1243761 |
0.717 |
|
2013 |
Nycholat CM, Peng W, McBride R, Antonopoulos A, de Vries RP, Polonskaya Z, Finn MG, Dell A, Haslam SM, Paulson JC. Synthesis of biologically active N- and O-linked glycans with multisialylated poly-N-acetyllactosamine extensions using P. damsela α2-6 sialyltransferase. Journal of the American Chemical Society. 135: 18280-3. PMID 24256304 DOI: 10.1021/Ja409781C |
0.698 |
|
2013 |
Macauley MS, Pfrengle F, Rademacher C, Nycholat CM, Gale AJ, von Drygalski A, Paulson JC. Antigenic liposomes displaying CD22 ligands induce antigen-specific B cell apoptosis. The Journal of Clinical Investigation. 123: 3074-83. PMID 23722906 DOI: 10.1172/Jci69187 |
0.573 |
|
2013 |
Kawasaki N, Vela JL, Nycholat CM, Rademacher C, Khurana A, van Rooijen N, Crocker PR, Kronenberg M, Paulson JC. Targeted delivery of lipid antigen to macrophages via the CD169/sialoadhesin endocytic pathway induces robust invariant natural killer T cell activation. Proceedings of the National Academy of Sciences of the United States of America. 110: 7826-31. PMID 23610394 DOI: 10.1073/Pnas.1219888110 |
0.573 |
|
2012 |
Zhu X, McBride R, Nycholat CM, Yu W, Paulson JC, Wilson IA. Influenza virus neuraminidases with reduced enzymatic activity that avidly bind sialic Acid receptors. Journal of Virology. 86: 13371-83. PMID 23015718 DOI: 10.1128/Jvi.01426-12 |
0.572 |
|
2012 |
Nycholat CM, Rademacher C, Kawasaki N, Paulson JC. In silico-aided design of a glycan ligand of sialoadhesin for in vivo targeting of macrophages. Journal of the American Chemical Society. 134: 15696-9. PMID 22967315 DOI: 10.1021/Ja307501E |
0.56 |
|
2012 |
Bundle DR, Nycholat C, Costello C, Rennie R, Lipinski T. Design of a Candida albicans disaccharide conjugate vaccine by reverse engineering a protective monoclonal antibody. Acs Chemical Biology. 7: 1754-63. PMID 22877569 DOI: 10.1021/Cb300345E |
0.562 |
|
2012 |
Rhee JK, Baksh M, Nycholat C, Paulson JC, Kitagishi H, Finn MG. Glycan-targeted virus-like nanoparticles for photodynamic therapy. Biomacromolecules. 13: 2333-8. PMID 22827531 DOI: 10.1021/Bm300578P |
0.547 |
|
2012 |
Peng W, Pranskevich J, Nycholat C, Gilbert M, Wakarchuk W, Paulson JC, Razi N. Helicobacter pylori β1,3-N-acetylglucosaminyltransferase for versatile synthesis of type 1 and type 2 poly-LacNAcs on N-linked, O-linked and I-antigen glycans. Glycobiology. 22: 1453-64. PMID 22786570 DOI: 10.1093/Glycob/Cws101 |
0.503 |
|
2012 |
Chen WC, Kawasaki N, Nycholat CM, Han S, Pilotte J, Crocker PR, Paulson JC. Antigen delivery to macrophages using liposomal nanoparticles targeting sialoadhesin/CD169. Plos One. 7: e39039. PMID 22723922 DOI: 10.1371/Journal.Pone.0039039 |
0.564 |
|
2012 |
Xu R, Zhu X, McBride R, Nycholat CM, Yu W, Paulson JC, Wilson IA. Functional balance of the hemagglutinin and neuraminidase activities accompanies the emergence of the 2009 H1N1 influenza pandemic. Journal of Virology. 86: 9221-32. PMID 22718832 DOI: 10.1128/Jvi.00697-12 |
0.571 |
|
2012 |
Rademacher C, Bru T, McBride R, Robison E, Nycholat CM, Kremer EJ, Paulson JC. A Siglec-like sialic-acid-binding motif revealed in an adenovirus capsid protein. Glycobiology. 22: 1086-91. PMID 22522600 DOI: 10.1093/Glycob/Cws073 |
0.524 |
|
2012 |
Nycholat CM, McBride R, Ekiert DC, Xu R, Rangarajan J, Peng W, Razi N, Gilbert M, Wakarchuk W, Wilson IA, Paulson JC. Recognition of sialylated poly-N-acetyllactosamine chains on N- and O-linked glycans by human and avian influenza A virus hemagglutinins. Angewandte Chemie (International Ed. in English). 51: 4860-3. PMID 22505324 DOI: 10.1002/Anie.201200596 |
0.566 |
|
2012 |
Xu R, McBride R, Nycholat CM, Paulson JC, Wilson IA. Structural characterization of the hemagglutinin receptor specificity from the 2009 H1N1 influenza pandemic. Journal of Virology. 86: 982-90. PMID 22072785 DOI: 10.1128/Jvi.06322-11 |
0.599 |
|
2012 |
Schnaar R, Paulson JC, Macauley MS, Nycholat C, Pfrengle F, Rademacher C, Mahan A, Dionne K, Suscovich T, Alter G, Katoh T, Kiwamoto T, Brummet M, Bochner B, Tiemeyer M, et al. Program and abstracts for the 2012 Joint Meeting of the Society for Glycobiology & American Society for Matrix Biology Glycobiology. 22: 1518-1650. DOI: 10.1093/Glycob/Cws127 |
0.471 |
|
2011 |
Rhee JK, Hovlid M, Fiedler JD, Brown SD, Manzenrieder F, Kitagishi H, Nycholat C, Paulson JC, Finn MG. Colorful virus-like particles: fluorescent protein packaging by the Qβ capsid. Biomacromolecules. 12: 3977-81. PMID 21995513 DOI: 10.1021/Bm200983K |
0.503 |
|
2011 |
Zeng Y, Rademacher C, Nycholat CM, Futakawa S, Lemme K, Ernst B, Paulson JC. High affinity sialoside ligands of myelin associated glycoprotein. Bioorganic & Medicinal Chemistry Letters. 21: 5045-9. PMID 21561770 DOI: 10.1016/J.Bmcl.2011.04.068 |
0.519 |
|
2009 |
Nycholat CM, Bundle DR. Synthesis of monodeoxy and mono-O-methyl congeners of methyl beta-D-mannopyranosyl-(1-->2)-beta-D-mannopyranoside for epitope mapping of anti-Candida albicans antibodies. Carbohydrate Research. 344: 1397-411. PMID 19679227 DOI: 10.1016/j.carres.2009.07.008 |
0.431 |
|
2009 |
Nycholat CM, Bundle DR. Synthesis of monodeoxy and mono-O-methyl congeners of methyl beta-D-mannopyranosyl-(1-->2)-beta-D-mannopyranoside for epitope mapping of anti-Candida albicans antibodies. Carbohydrate Research. 344: 555-69. PMID 19249752 DOI: 10.1016/J.Carres.2008.12.011 |
0.43 |
|
2002 |
Pedras MS, Nycholat CM, Montaut S, Xu Y, Khan AQ. Chemical defenses of crucifers: elicitation and metabolism of phytoalexins and indole-3-acetonitrile in brown mustard and turnip. Phytochemistry. 59: 611-25. PMID 11867093 DOI: 10.1016/S0031-9422(02)00026-2 |
0.553 |
|
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