Tatjana C Jakobs - Publications

Affiliations: 
Harvard Medical School - Massachusetts Eye and Ear 
Area:
Visual system, glaucoma, retinal ganglion cells, astrocytes

35 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Zhu Y, Wang R, Pappas AC, Seifert P, Savol A, Sadreyev RI, Sun D, Jakobs TC. Astrocytes in the Optic Nerve Are Heterogeneous in Their Reactivity to Glaucomatous Injury. Cells. 12. PMID 37681863 DOI: 10.3390/cells12172131  0.675
2023 Li S, Jakobs TC. Vitamin C protects retinal ganglion cells via SPP1 in glaucoma and after optic nerve damage. Life Science Alliance. 6. PMID 37160307 DOI: 10.26508/lsa.202301976  0.302
2023 Waxman S, Quinn M, Donahue C, Falo LD, Sun D, Jakobs TC, Sigal IA. Individual astrocyte morphology in the collagenous lamina cribrosa revealed by multicolor DiOlistic labeling. Experimental Eye Research. 230: 109458. PMID 36965593 DOI: 10.1016/j.exer.2023.109458  0.65
2022 Hu B, Huang Y, Jakobs TC, Kang Q, Lv Z, Liu W, Wang R. Viability of mitochondria-labeled retinal ganglion cells in organotypic retinal explant cultures by two methods. Experimental Eye Research. 109311. PMID 36403849 DOI: 10.1016/j.exer.2022.109311  0.411
2022 Tan Z, Guo Y, Shrestha M, Sun D, Gregory-Ksander M, Jakobs TC. Microglia depletion exacerbates retinal ganglion cell loss in a mouse model of glaucoma. Experimental Eye Research. 225: 109273. PMID 36206859 DOI: 10.1016/j.exer.2022.109273  0.687
2018 Zhu Y, Pappas AC, Wang R, Seifert P, Sun D, Jakobs TC. Ultrastructural Morphology of the Optic Nerve Head in Aged and Glaucomatous Mice. Investigative Ophthalmology & Visual Science. 59: 3984-3996. PMID 30098187 DOI: 10.1167/Iovs.18-23885  0.628
2018 Choi HJ, Wang R, Jakobs TC. Single-Cell Dissociation and Characterization in the Murine Retina and Optic Nerve. Methods in Molecular Biology (Clifton, N.J.). 1695: 311-334. PMID 29190033 DOI: 10.1007/978-1-4939-7407-8_21  0.489
2017 Sun D, Moore S, Jakobs TC. Optic nerve astrocyte reactivity protects function in experimental glaucoma and other nerve injuries. The Journal of Experimental Medicine. PMID 28416649 DOI: 10.1084/Jem.20160412  0.662
2017 Tamm ER, Ethier CR, Burgoyne C, Ethier CR, Tamm ER, Stowell C, Dowling JE, Downs C, Ellisman MH, Fisher S, Fortune B, Fruttiger M, Jakobs T, Lewis G, et al. Biological aspects of axonal damage in glaucoma: A brief review. Experimental Eye Research. PMID 28223179 DOI: 10.1016/J.Exer.2017.02.006  0.665
2017 Wang R, Seifert P, Jakobs TC. Astrocytes in the Optic Nerve Head of Glaucomatous Mice Display a Characteristic Reactive Phenotype. Investigative Ophthalmology & Visual Science. 58: 924-932. PMID 28170536 DOI: 10.1167/Iovs.16-20571  0.523
2017 Jakobs TC. Ex Vivo Imaging of the Murine Optic Nerve Head. Investigative Ophthalmology & Visual Science. 58: 734. PMID 28152143 DOI: 10.1167/Iovs.17-21422  0.396
2016 Gao S, Jakobs TC. Mice Homozygous for a Deletion in the Glaucoma Susceptibility Locus INK4 Show Increased Vulnerability of Retinal Ganglion Cells to Elevated Intraocular Pressure. The American Journal of Pathology. PMID 26883755 DOI: 10.1016/J.Ajpath.2015.11.026  0.398
2015 Berry RH, Qu J, John SW, Howell GR, Jakobs TC. Synapse Loss and Dendrite Remodeling in a Mouse Model of Glaucoma. Plos One. 10: e0144341. PMID 26637126 DOI: 10.1371/Journal.Pone.0144341  0.465
2015 Choi HJ, Sun D, Jakobs TC. Astrocytes in the optic nerve head express putative mechanosensitive channels. Molecular Vision. 21: 749-66. PMID 26236150  0.613
2015 Choi HJ, Sun D, Jakobs TC. Isolation of intact astrocytes from the optic nerve head of adult mice. Experimental Eye Research. 137: 103-10. PMID 26093274 DOI: 10.1016/J.Exer.2015.06.014  0.704
2015 Choi HJ, Sun D, Jakobs TC. Isolation of intact astrocytes from the optic nerve head of adult mice Experimental Eye Research. 137: 103-110. DOI: 10.1016/j.exer.2015.06.014  0.606
2014 Jakobs TC. Differential gene expression in glaucoma. Cold Spring Harbor Perspectives in Medicine. 4: a020636. PMID 24985133 DOI: 10.1101/Cshperspect.A020636  0.342
2013 Qu J, Jakobs TC. The Time Course of Gene Expression during Reactive Gliosis in the Optic Nerve. Plos One. 8: e67094. PMID 23826199 DOI: 10.1371/Journal.Pone.0067094  0.496
2013 Sun D, Qu J, Jakobs TC. Reversible reactivity by optic nerve astrocytes. Glia. 61: 1218-35. PMID 23650091 DOI: 10.1002/Glia.22507  0.684
2013 Lye-Barthel M, Sun D, Jakobs TC. Morphology of astrocytes in a glaucomatous optic nerve. Investigative Ophthalmology & Visual Science. 54: 909-17. PMID 23322566 DOI: 10.1167/Iovs.12-10109  0.693
2012 Sun D, Jakobs TC. Structural remodeling of astrocytes in the injured CNS. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. 18: 567-88. PMID 21982954 DOI: 10.1177/1073858411423441  0.636
2011 Koizumi A, Jakobs TC, Masland RH. Regular mosaic of synaptic contacts among three retinal neurons. The Journal of Comparative Neurology. 519: 341-57. PMID 21165978 DOI: 10.1002/Cne.22522  0.701
2010 Sun D, Lye-Barthel M, Masland RH, Jakobs TC. Structural remodeling of fibrous astrocytes after axonal injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 14008-19. PMID 20962222 DOI: 10.1523/Jneurosci.3605-10.2010  0.726
2010 Alt C, Biss DP, Tajouri N, Jakobs TC, Lin CP. An adaptive-optics scanning laser ophthalmoscope for imaging murine retinal microstructure Progress in Biomedical Optics and Imaging - Proceedings of Spie. 7550. DOI: 10.1117/12.840583  0.424
2009 Sun D, Lye-Barthel M, Masland RH, Jakobs TC. The morphology and spatial arrangement of astrocytes in the optic nerve head of the mouse. The Journal of Comparative Neurology. 516: 1-19. PMID 19562764 DOI: 10.1002/Cne.22058  0.753
2008 Jakobs TC, Koizumi A, Masland RH. The spatial distribution of glutamatergic inputs to dendrites of retinal ganglion cells. The Journal of Comparative Neurology. 510: 221-36. PMID 18623177 DOI: 10.1002/Cne.21795  0.658
2007 Lye MH, Jakobs TC, Masland RH, Koizumi A. Organotypic culture of adult rabbit retina. Journal of Visualized Experiments : Jove. 190. PMID 18978996 DOI: 10.3791/190  0.691
2007 Howell GR, Libby RT, Jakobs TC, Smith RS, Phalan FC, Barter JW, Barbay JM, Marchant JK, Mahesh N, Porciatti V, Whitmore AV, Masland RH, John SW. Axons of retinal ganglion cells are insulted in the optic nerve early in DBA/2J glaucoma. The Journal of Cell Biology. 179: 1523-37. PMID 18158332 DOI: 10.1083/Jcb.200706181  0.689
2007 Jakobs TC, Ben Y, Masland RH. Expression of mRNA for glutamate receptor subunits distinguishes the major classes of retinal neurons, but is less specific for individual cell types. Molecular Vision. 13: 933-48. PMID 17653033  0.578
2007 Koizumi A, Zeck G, Ben Y, Masland RH, Jakobs TC. Organotypic culture of physiologically functional adult mammalian retinas. Plos One. 2: e221. PMID 17311097 DOI: 10.1371/Journal.Pone.0000221  0.72
2006 Enoki R, Jakobs TC, Koizumi A. Horizontal slice preparation of the retina. Journal of Visualized Experiments : Jove. 108. PMID 18704185 DOI: 10.3791/108  0.582
2005 Jakobs TC, Libby RT, Ben Y, John SW, Masland RH. Retinal ganglion cell degeneration is topological but not cell type specific in DBA/2J mice. The Journal of Cell Biology. 171: 313-25. PMID 16247030 DOI: 10.1083/Jcb.200506099  0.71
2005 Lin B, Jakobs TC, Masland RH. Different functional types of bipolar cells use different gap-junctional proteins. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 6696-701. PMID 16014731 DOI: 10.1523/Jneurosci.1894-05.2005  0.652
2004 Koizumi A, Jakobs TC, Masland RH. Inward rectifying currents stabilize the membrane potential in dendrites of mouse amacrine cells: patch-clamp recordings and single-cell RT-PCR. Molecular Vision. 10: 328-40. PMID 15152185  0.632
2003 Jakobs TC, Ben Y, Masland RH. CD15 immunoreactive amacrine cells in the mouse retina. The Journal of Comparative Neurology. 465: 361-71. PMID 12966561 DOI: 10.1002/Cne.10845  0.615
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