Michael Shtutman

Affiliations: 
University of South Carolina, Columbia, SC 
Area:
COPI complex, cell-cell adhesion, focal adhesion, wnt signaling, L1CAM, tetraspanins, cancer biology
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"Michael Shtutman"

Parents

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Alexander D. Bershadsky post-doc 1997-2002
Avri B. Ze'ev post-doc 1997-2002
Benjamin Geiger research scientist 1999-2002
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Publications

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McDermott M, Györffy B, Chumanevich A, et al. (2016) Abstract P5-04-07: CDK8 protein complex as a potential biomarker and therapeutic target in breast cancer Cancer Research. 76
Oliver DJ, Chaparala A, Okafor E, et al. (2014) Identification of cancer-specific COPI inhibitors and their associated apoptotic cell death pathways Cancer Research. 74
Levina E, Chen M, Carkner R, et al. (2012) Paracrine Hedgehog increases the steroidogenic potential of prostate stromal cells in a Gli-dependent manner. The Prostate. 72: 817-24
Shtutman M, Baig M, Levina E, et al. (2011) Tumor-specific silencing of COPZ2 gene encoding coatomer protein complex subunit ζ 2 renders tumor cells dependent on its paralogous gene COPZ1. Proceedings of the National Academy of Sciences of the United States of America. 108: 12449-54
Tanner MJ, Welliver RC, Chen M, et al. (2011) Effects of androgen receptor and androgen on gene expression in prostate stromal fibroblasts and paracrine signaling to prostate cancer cells. Plos One. 6: e16027
Chen M, Feuerstein MA, Levina E, et al. (2010) Hedgehog/Gli supports androgen signaling in androgen deprived and androgen independent prostate cancer cells. Molecular Cancer. 9: 89
Shtutman M, Maliyekkel A, Shao Y, et al. (2010) Function-based gene identification using enzymatically generated normalized shRNA library and massive parallel sequencing. Proceedings of the National Academy of Sciences of the United States of America. 107: 7377-82
Demidenko ZN, Shtutman M, Blagosklonny MV. (2009) Pharmacologic inhibition of MEK and PI-3K converges on the mTOR/S6 pathway to decelerate cellular senescence. Cell Cycle (Georgetown, Tex.). 8: 1896-900
Shtutman M, Chausovsky A, Prager-Khoutorsky M, et al. (2008) Signaling function of alpha-catenin in microtubule regulation. Cell Cycle (Georgetown, Tex.). 7: 2377-83
Yates KE, Korbel GA, Shtutman M, et al. (2008) Repression of the SUMO-specific protease Senp1 induces p53-dependent premature senescence in normal human fibroblasts. Aging Cell. 7: 609-21
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