Muralikrishna Lella, Ph. D.

Affiliations: 
2012-2019 Department of Biological Sciences Indian Institute of Science Education and Research (IISER) Bhopal 
 2019- University of Nevada at Reno, Reno, NV, United States 
Area:
Peptide Design, Peptide Therapeutics, Quorum Sensing, Transmembrane Ion Channels
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Publications

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McBrayer DN, Ghosh U, Lella M, et al. (2022) Peptoid-Peptide Hybrid Analogs of the Enterococcus faecalis Fsr Auto-Inducing Peptide (AIP) Reveal Crucial Structure-Activity Relationships. Chembiochem : a European Journal of Chemical Biology
Oh MW, Lella M, Kuo SH, et al. (2022) Pharmacological Evaluation of Synthetic Dominant-Negative Peptides Derived from the Competence-Stimulating Peptide of . Acs Pharmacology & Translational Science. 5: 299-305
Lella M, Oh MW, Kuo SH, et al. (2022) Attenuating the Competence Regulon Using Urea-Bridged Cyclic Dominant-Negative Competence-Stimulating Peptide Analogs. Journal of Medicinal Chemistry. 65: 6826-6839
Milly TA, Buttner AR, Rieth N, et al. (2022) Optimizing CSP1 analogs for modulating quorum sensing in with bulky, hydrophobic nonproteogenic amino acid substitutions. Rsc Chemical Biology. 3: 301-311
Lella M, Tal-Gan Y. (2021) Strategies to Attenuate the Competence Regulon in . Peptide Science (Hoboken, N.J.). 113
Lella M, Mahalakshmi R. (2018) Direct Structural Annotation of Membrane Protein Aggregation Loci using Peptide-Based Reverse Mapping. Journal of Physical Chemistry Letters. 9: 2967-2971
Lella M, Mahalakshmi R. (2017) Metamorphic Proteins: Emergence of Dual Protein Folds from One Primary Sequence. Biochemistry. 56: 2971-2984
Lella M, Mahalakshmi R. (2017) Solvation driven conformational transitions in the second transmembrane domain of mycobacteriophage holin. Biopolymers. 108
Lella M, Mahalakshmi R. (2016) Engineering a Transmembrane Nanopore Ion Channel from a Membrane Breaker Peptide. Journal of Physical Chemistry Letters. 7: 2298-2303
Lella M, Kamilla S, Jain V, et al. (2016) Molecular Mechanism of Holin Transmembrane Domain I in Pore Formation and Bacterial Cell Death. Acs Chemical Biology
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