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Benjamin S. Freedman, Ph.D. - Publications

Affiliations: 
2009 University of California, Berkeley, Berkeley, CA, United States 
Area:
Mitotic spindle assembly and function in Xenopus laevis
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30 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Liu E, Radmanesh B, Chung BH, Donnan MD, Yi D, Dadi A, Smith KD, Himmelfarb J, Li M, Freedman BS, Lin J. Profiling Nephropathy Risk Variants in Genome-Edited Kidney Organoids with Single-Cell Transcriptomics. Kidney360. 1: 203-215. PMID 32656538 DOI: 10.34067/Kid.0000422019  0.353
2020 Luciani A, Freedman BS. Induced pluripotent stem cells provide mega insights into kidney disease. Kidney International. 98: 54-57. PMID 32571490 DOI: 10.1016/J.Kint.2020.04.033  0.362
2020 Refaeli I, Hughes MR, Wong AK, Bissonnette MLZ, Roskelley CD, Wayne Vogl A, Barbour SJ, Freedman BS, McNagny KM. Distinct Functional Requirements for Podocalyxin in Immature and Mature Podocytes Reveal Mechanisms of Human Kidney Disease. Scientific Reports. 10: 9419. PMID 32523052 DOI: 10.1038/S41598-020-64907-3  0.344
2020 Barabino A, Flamier A, Hanna R, Héon E, Freedman BS, Bernier G. Deregulation of Neuro-Developmental Genes and Primary Cilium Cytoskeleton Anomalies in iPSC Retinal Sheets from Human Syndromic Ciliopathies. Stem Cell Reports. PMID 32160518 DOI: 10.1016/J.Stemcr.2020.02.005  0.332
2019 Nam SA, Seo E, Kim JW, Kim HW, Kim HL, Kim K, Kim TM, Ju JH, Gomez IG, Uchimura K, Humphreys BD, Yang CW, Lee JY, Kim J, Cho DW, ... Freedman BS, et al. Graft immaturity and safety concerns in transplanted human kidney organoids. Experimental & Molecular Medicine. 51: 145. PMID 31776328 DOI: 10.1038/S12276-019-0336-X  0.36
2019 Cruz NM, Freedman BS. Differentiation of human kidney organoids from pluripotent stem cells. Methods in Cell Biology. 153: 133-150. PMID 31395376 DOI: 10.1016/Bs.Mcb.2019.05.003  0.397
2019 Kaverina NV, Eng DG, Freedman BS, Kutz JN, Chozinski TJ, Vaughan JC, Miner JH, Pippin JW, Shankland SJ. Dual lineage tracing shows that glomerular parietal epithelial cells can transdifferentiate toward the adult podocyte fate. Kidney International. PMID 31200942 DOI: 10.1016/J.Kint.2019.03.014  0.326
2019 Freedman BS. Producing Purer Podocytes. Journal of the American Society of Nephrology : Jasn. PMID 30635374 DOI: 10.1681/Asn.2018101045  0.342
2019 Harder JL, Menon R, Otto EA, Zhou J, Eddy S, Wys NL, O'Connor C, Luo J, Nair V, Cebrian C, Spence JR, Bitzer M, Troyanskaya OG, Hodgin JB, Wiggins RC, ... Freedman BS, et al. Organoid single cell profiling identifies a transcriptional signature of glomerular disease. Jci Insight. 4. PMID 30626756 DOI: 10.1172/Jci.Insight.122697  0.392
2018 Freedman BS. Better Being Single? Omics Improves Kidney Organoids. Nephron. 141: 1-5. PMID 30554217 DOI: 10.1159/000496009  0.369
2018 Czerniecki SM, Cruz NM, Harder JL, Menon R, Annis J, Otto EA, Gulieva RE, Islas LV, Kim YK, Tran LM, Martins TJ, Pippin JW, Fu H, Kretzler M, Shankland SJ, ... ... Freedman BS, et al. High-Throughput Screening Enhances Kidney Organoid Differentiation from Human Pluripotent Stem Cells and Enables Automated Multidimensional Phenotyping. Cell Stem Cell. PMID 29779890 DOI: 10.1016/J.Stem.2018.04.022  0.328
2018 Cruz NM, Freedman BS. CRISPR Gene Editing in the Kidney. American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation. PMID 29606501 DOI: 10.1053/J.Ajkd.2018.02.347  0.37
2018 Eng DG, Kaverina NV, Schneider RRS, Freedman BS, Gross KW, Miner JH, Pippin JW, Shankland SJ. Detection of renin lineage cell transdifferentiation to podocytes in the kidney glomerulus with dual lineage tracing. Kidney International. PMID 29580637 DOI: 10.1016/J.Kint.2018.01.014  0.32
2018 Jing P, Liu Y, Keeler EG, Cruz NM, Freedman BS, Lin LY. Optical tweezers system for live stem cell organization at the single-cell level. Biomedical Optics Express. 9: 771-779. PMID 29552411 DOI: 10.1364/Boe.9.000771  0.308
2017 Freedman BS. Hopes and Difficulties for Blastocyst Complementation. Nephron. PMID 29017167 DOI: 10.1159/000480370  0.302
2017 Cruz NM, Song X, Czerniecki SM, Gulieva RE, Churchill AJ, Kim YK, Winston K, Tran LM, Diaz MA, Fu H, Finn LS, Pei Y, Himmelfarb J, Freedman BS. Organoid cystogenesis reveals a critical role of microenvironment in human polycystic kidney disease. Nature Materials. PMID 28967916 DOI: 10.1038/Nmat4994  0.37
2017 Kim YK, Refaeli I, Brooks CR, Jing P, Gulieva RE, Hughes MR, Cruz NM, Liu Y, Churchill AJ, Wang Y, Fu H, Pippin JW, Lin LY, Shankland SJ, Vogl AW, ... ... Freedman BS, et al. Gene-edited Human Kidney Organoids Reveal Mechanisms of Disease in Podocyte Development. Stem Cells (Dayton, Ohio). PMID 28905451 DOI: 10.1002/Stem.2707  0.398
2017 Shankland SJ, Freedman BS, Pippin JW. Can podocytes be regenerated in adults? Current Opinion in Nephrology and Hypertension. PMID 28306565 DOI: 10.1097/Mnh.0000000000000311  0.321
2017 Tögel F, Valerius MT, Freedman BS, Latrino R, Grinstein M, Bonventre JV. Repair after nephron ablation reveals limitations of neonatal neonephrogenesis. Jci Insight. 2: e88848. PMID 28138555 DOI: 10.1172/Jci.Insight.88848  0.331
2016 Pang P, Abbott M, Chang SL, Abdi M, Chauhan N, Mistri M, Ghofrani J, Fucci QA, Walker C, Leonardi C, Grady S, Halim A, Hoffman R, Lu T, Cao H, ... ... Freedman BS, et al. Human vascular progenitor cells derived from renal arteries are endothelial-like and assist in the repair of injured renal capillary networks. Kidney International. PMID 27692806 DOI: 10.1016/J.Kint.2016.07.037  0.329
2016 Freedman BS, Steinman TI, Zhou J, Bonventre JV. Modeling Polycystic Kidney Disease Cystogenesis with Genome-Modified Human Pluripotent Stem Cells Biophysical Journal. 110: 146a. DOI: 10.1016/J.Bpj.2015.11.824  0.406
2015 Freedman BS. Modeling Kidney Disease with iPS Cells. Biomarker Insights. 10: 153-69. PMID 26740740 DOI: 10.4137/Bmi.S20054  0.39
2015 Freedman BS, Brooks CR, Lam AQ, Fu H, Morizane R, Agrawal V, Saad AF, Li MK, Hughes MR, Werff RV, Peters DT, Lu J, Baccei A, Siedlecki AM, Valerius MT, et al. Modelling kidney disease with CRISPR-mutant kidney organoids derived from human pluripotent epiblast spheroids. Nature Communications. 6: 8715. PMID 26493500 DOI: 10.1038/Ncomms9715  0.411
2014 Lam AQ, Freedman BS, Bonventre JV. Directed differentiation of pluripotent stem cells to kidney cells. Seminars in Nephrology. 34: 445-61. PMID 25217273 DOI: 10.1016/J.Semnephrol.2014.06.011  0.405
2013 Freedman BS, Lam AQ, Sundsbak JL, Iatrino R, Su X, Koon SJ, Wu M, Daheron L, Harris PC, Zhou J, Bonventre JV. Reduced ciliary polycystin-2 in induced pluripotent stem cells from polycystic kidney disease patients with PKD1 mutations. Journal of the American Society of Nephrology : Jasn. 24: 1571-86. PMID 24009235 DOI: 10.1681/Asn.2012111089  0.321
2012 Xiao B, Freedman BS, Miller KE, Heald R, Marko JF. Histone H1 compacts DNA under force and during chromatin assembly. Molecular Biology of the Cell. 23: 4864-71. PMID 23097493 DOI: 10.1091/Mbc.E12-07-0518  0.547
2011 Fu H, Freedman BS, Lim CT, Heald R, Yan J. Atomic force microscope imaging of chromatin assembled in Xenopus laevis egg extract. Chromosoma. 120: 245-54. PMID 21369955 DOI: 10.1007/S00412-010-0307-4  0.534
2010 Freedman BS, Miller KE, Heald R. Xenopus egg extracts increase dynamics of histone H1 on sperm chromatin. Plos One. 5. PMID 20927327 DOI: 10.1371/Journal.Pone.0013111  0.57
2010 Freedman BS, Heald R. Functional comparison of H1 histones in Xenopus reveals isoform-specific regulation by Cdk1 and RanGTP. Current Biology : Cb. 20: 1048-52. PMID 20471264 DOI: 10.1016/J.Cub.2010.04.025  0.592
2005 Maresca TJ, Freedman BS, Heald R. Histone H1 is essential for mitotic chromosome architecture and segregation in Xenopus laevis egg extracts. The Journal of Cell Biology. 169: 859-69. PMID 15967810 DOI: 10.1083/Jcb.200503031  0.628
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