Sean F. Maloney, Ph.D.

Affiliations: 
2010 University of Pennsylvania, Philadelphia, PA, United States 
Area:
Chemical Engineering, Biomedical Engineering
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"Sean Maloney"

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Scott L. Diamond grad student 2010 Penn
 (Microfluidic focal injury models of thrombosis and hemostasis.)
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Publications

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Jiménez JM, Prasad V, Yu MD, et al. (2014) Macro- and microscale variables regulate stent haemodynamics, fibrin deposition and thrombomodulin expression. Journal of the Royal Society, Interface / the Royal Society. 11: 20131079
Stolla M, Stefanini L, Roden RC, et al. (2011) The kinetics of αIIbβ3 activation determines the size and stability of thrombi in mice: implications for antiplatelet therapy. Blood. 117: 1005-13
Wannemacher KM, Zhu L, Jiang H, et al. (2010) Diminished contact-dependent reinforcement of Syk activation underlies impaired thrombus growth in mice lacking Semaphorin 4D. Blood. 116: 5707-15
Maloney SF, Brass LF, Diamond SL. (2010) P2Y12 or P2Y1 inhibitors reduce platelet deposition in a microfluidic model of thrombosis while apyrase lacks efficacy under flow conditions. Integrative Biology : Quantitative Biosciences From Nano to Macro. 2: 183-92
Schmaier AA, Zou Z, Kazlauskas A, et al. (2009) Molecular priming of Lyn by GPVI enables an immune receptor to adopt a hemostatic role. Proceedings of the National Academy of Sciences of the United States of America. 106: 21167-72
Fein DE, Limberis MP, Maloney SF, et al. (2009) Cationic lipid formulations alter the in vivo tropism of AAV2/9 vector in lung. Molecular Therapy : the Journal of the American Society of Gene Therapy. 17: 2078-87
Zhu L, Stalker TJ, Fong KP, et al. (2009) Disruption of SEMA4D ameliorates platelet hypersensitivity in dyslipidemia and confers protection against the development of atherosclerosis. Arteriosclerosis, Thrombosis, and Vascular Biology. 29: 1039-45
Stefanini L, Stolla M, Maloney SF, et al. (2009) Revised Model for Platelet Adhesion to Collagen. Blood. 114: 2999-2999
Neeves KB, Maloney SF, Fong KP, et al. (2008) Microfluidic focal thrombosis model for measuring murine platelet deposition and stability: PAR4 signaling enhances shear-resistance of platelet aggregates. Journal of Thrombosis and Haemostasis : Jth. 6: 2193-201
Bur AM, Fong KP, Neeves KB, et al. (2008) Microfluidic Flow Studies of Murine Thrombus Formation and Stability on Collagen. Blood. 112: 1835-1835
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