Brian A. Kidd, Ph.D.

Affiliations: 
2009 University of Washington, Seattle, Seattle, WA 
Area:
Biomedical Engineering
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"Brian Kidd"

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Wendy Thomas grad student 2009 University of Washington
 (Computational modeling and design of conformational change in allosteric proteins.)
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Publications

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Perumal D, Lagana' A, Melnekoff D, et al. (2016) Network Modeling Reveals CDC42BPA and CLEC11A As Novel Driver Genes of t(4; 14) Multiple Myeloma Blood. 128: 802-802
Rodriguez VB, Kidd BA, Interlandi G, et al. (2013) Allosteric coupling in the bacterial adhesive protein FimH. The Journal of Biological Chemistry. 288: 24128-39
Aprikian P, Interlandi G, Kidd BA, et al. (2011) The bacterial fimbrial tip acts as a mechanical force sensor. Plos Biology. 9: e1000617
Le Trong I, Aprikian P, Kidd BA, et al. (2010) Donor strand exchange and conformational changes during E. coli fimbrial formation. Journal of Structural Biology. 172: 380-8
Le Trong I, Aprikian P, Kidd BA, et al. (2010) Structural basis for mechanical force regulation of the adhesin FimH via finger trap-like beta sheet twisting. Cell. 141: 645-55
Tchesnokova V, McVeigh AL, Kidd B, et al. (2010) Shear-enhanced binding of intestinal colonization factor antigen I of enterotoxigenic Escherichia coli. Molecular Microbiology. 76: 489-502
Kidd BA, Baker D, Thomas WE. (2009) Computation of conformational coupling in allosteric proteins. Plos Computational Biology. 5: e1000484
Thomas WE, Le Trong I, Aprikian P, et al. (2009) Allosteric Regulation Across a β-Sandwich Protein: How a Bacterial Adhesive Protein is Activated by Mechanical Force Biophysical Journal. 96: 548a
Yakovenko O, Sharma S, Forero M, et al. (2008) FimH forms catch bonds that are enhanced by mechanical force due to allosteric regulation. The Journal of Biological Chemistry. 283: 11596-605
Tchesnokova V, Aprikian P, Yakovenko O, et al. (2008) Integrin-like allosteric properties of the catch bond-forming FimH adhesin of Escherichia coli. The Journal of Biological Chemistry. 283: 7823-33
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