Zhenghe Wang, Ph.D.
Affiliations: | 2001 | University of Virginia, Charlottesville, VA |
Area:
Genetics, Microbiology BiologyGoogle:
"Zhenghe Wang"Parents
Sign in to add mentor| Michael F. Christman | grad student | 2001 | UVA | |
| (Pol kappa: A novel DNA polymerase required for sister chromatid cohesion and DNA repair.) | ||||
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Publications
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| Zhao Y, Feng X, Chen Y, et al. (2020) 5-fluorouracil enhances the anti-tumor activity of the glutaminase inhibitor CB-839 against PIK3CA-mutant colorectal cancers. Cancer Research |
| Zhao Y, Zhao X, Chen V, et al. (2019) Colorectal cancers utilize glutamine as an anaplerotic substrate of the TCA cycle in vivo. Scientific Reports. 9: 19180 |
| Bowler EH, Smith-Vidal A, Lester A, et al. (2019) Deep proteomic analysis of Dnmt1 mutant/hypomorphic colorectal cancer cells reveals dysregulation of epithelial-mesenchymal transition and subcellular re-localization of Beta-Catenin. Epigenetics. 1-15 |
| Zhao Y, Eads J, Bajor D, et al. (2019) Abstract LB-294: Targeting glutamine addiction of PIK3CA mutant colorectal cancers: From preclinical models to clinical trials Cancer Research. 79 |
| Eads JR, Krishnamurthi SS, Saltzman JN, et al. (2018) Phase I clinical trial of the glutaminase inhibitor CB-839 plus capecitabine in patients with advanced solid tumors. Journal of Clinical Oncology. 36: 2562-2562 |
| Zhao Y, Wang Z. (2018) Abstract 2379: PTPRT pseudo-phosphatase domain is a denitrase that contributes to its tumor suppressor function Cancer Research. 78: 2379-2379 |
| Feng X, Hao Y, Wang Z. (2016) Targeting glutamine metabolism in mutant colorectal cancers. Genes & Diseases. 3: 241-243 |
| Zhao Y, Scott A, Zhang P, et al. (2016) Regulation of paxillin-p130-PI3K-AKT signaling axis by Src and PTPRT impacts colon tumorigenesis. Oncotarget |
| Peyser ND, Wang L, Zeng Y, et al. (2016) STAT3 as a chemoprevention target in carcinogen-induced head and neck squamous cell carcinoma. Cancer Prevention Research (Philadelphia, Pa.) |
| Wang Z. (2016) Abstract B03: Oncogenic PIK3CA mutations reprogram glutamine metabolism in colorectal cancers Molecular Cancer Research. 14 |