Katherine A. Owen, Ph.D.
Affiliations: | 2007 | University of Virginia, Charlottesville, VA |
Area:
Microbiology Biology, Cell BiologyGoogle:
"Katherine Owen"Parents
Sign in to add mentorAmy H. Bouton | grad student | 2007 | UVA | |
(FAK and Pyk2 regulate the intracellular signaling networks required for integrin-mediated migration and phagocytosis by macrophages.) |
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Publications
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Thomas KS, Owen KA, Conger K, et al. (2019) Non-redundant functions of FAK and Pyk2 in intestinal epithelial repair. Scientific Reports. 9: 4497 |
Billings EA, Lee CS, Owen KA, et al. (2016) The adhesion GPCR BAI1 mediates macrophage ROS production and microbicidal activity against Gram-negative bacteria. Science Signaling. 9: ra14 |
Owen KA, Anderson CJ, Casanova JE. (2015) Salmonella Suppresses the TRIF-Dependent Type I Interferon Response in Macrophages. Mbio. 7 |
Das S, Sarkar A, Choudhury SS, et al. (2015) ELMO1 has an essential role in the internalization of Salmonella Typhimurium into enteric macrophages that impacts disease outcome. Cellular and Molecular Gastroenterology and Hepatology. 1: 311-324 |
Owen KA, Casanova JE. (2015) Salmonella Manipulates Autophagy to "Serve and Protect". Cell Host & Microbe. 18: 517-9 |
Owen KA, Meyer CB, Bouton AH, et al. (2014) Activation of focal adhesion kinase by Salmonella suppresses autophagy via an Akt/mTOR signaling pathway and promotes bacterial survival in macrophages. Plos Pathogens. 10: e1004159 |
Owen KA, Abshire MY, Tilghman RW, et al. (2011) FAK regulates intestinal epithelial cell survival and proliferation during mucosal wound healing. Plos One. 6: e23123 |
Das S, Owen KA, Ly KT, et al. (2011) Brain angiogenesis inhibitor 1 (BAI1) is a pattern recognition receptor that mediates macrophage binding and engulfment of Gram-negative bacteria. Proceedings of the National Academy of Sciences of the United States of America. 108: 2136-41 |
Abshire MY, Thomas KS, Owen KA, et al. (2011) Macrophage motility requires distinct α5β1/FAK and α4β1/paxillin signaling events. Journal of Leukocyte Biology. 89: 251-7 |
Owen KA, Pixley FJ, Thomas KS, et al. (2007) Regulation of lamellipodial persistence, adhesion turnover, and motility in macrophages by focal adhesion kinase. The Journal of Cell Biology. 179: 1275-87 |