Laurent Sabbagh, Ph.D.

Affiliations: 
2004 McGill University, Montreal, QC, Canada 
Area:
Immunology, Molecular Biology
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"Laurent Sabbagh"

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Rafick P. Sekaly grad student 2004 McGill
 (Transcriptional regulation of the murine caspase-3 gene during T cell activation.)
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Publications

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Gavegnano C, Brehm JH, Dupuy FP, et al. (2017) Novel mechanisms to inhibit HIV reservoir seeding using Jak inhibitors. Plos Pathogens. 13: e1006740
Oussa NA, Dahmani A, Gomis M, et al. (2016) VEGF Requires the Receptor NRP-1 To Inhibit Lipopolysaccharide-Dependent Dendritic Cell Maturation. Journal of Immunology (Baltimore, Md. : 1950). 197: 3927-3935
Hwang SH, Jung SH, Lee S, et al. (2015) Leukocyte-specific protein 1 regulates T-cell migration in rheumatoid arthritis. Proceedings of the National Academy of Sciences of the United States of America
Pike KA, Hutchins AP, Vinette V, et al. (2014) Protein tyrosine phosphatase 1B is a regulator of the interleukin-10-induced transcriptional program in macrophages. Science Signaling. 7: ra43
Sabbagh L, Andreeva D, Laramée GD, et al. (2013) Leukocyte-specific protein 1 links TNF receptor-associated factor 1 to survival signaling downstream of 4-1BB in T cells. Journal of Leukocyte Biology. 93: 713-21
Oussa NA, Soumounou Y, Sabbagh L. (2013) TRAF1 phosphorylation on Serine 139 modulates NF-κB activity downstream of 4-1BB in T cells. Biochemical and Biophysical Research Communications. 432: 129-34
Watts TH, Lin GH, Wang C, et al. (2011) Role of 4-1BBL and TRAF1 in the CD8 T cell response to influenza virus and HIV. Advances in Experimental Medicine and Biology. 691: 177-86
Sabbagh L, Pulle G, Liu Y, et al. (2008) ERK-dependent Bim modulation downstream of the 4-1BB-TRAF1 signaling axis is a critical mediator of CD8 T cell survival in vivo. Journal of Immunology (Baltimore, Md. : 1950). 180: 8093-101
Sabbagh L, Srokowski CC, Pulle G, et al. (2006) A critical role for TNF receptor-associated factor 1 and Bim down-regulation in CD8 memory T cell survival. Proceedings of the National Academy of Sciences of the United States of America. 103: 18703-8
Moldovan MC, Sabbagh L, Breton G, et al. (2006) Triggering of T cell activation via CD4 dimers. Journal of Immunology (Baltimore, Md. : 1950). 176: 5438-45
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