Jean-Francois Giguere, Ph.D.

Affiliations: 
2004 Universite Laval (Canada) 
Area:
Microbiology Biology
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"Jean-Francois Giguere"

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Michel J. Tremblay grad student 2004 Universite Laval (Canada)
 (Acquisition des molecules de co-stimulation CD28, CD152, CD80 et CD86 par le virus de l'immunodeficience humaine de type 1 (VIH-1).)
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Publications

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Jung D, Cayer M, Proulx M, et al. (2007) Effects of c-Src Overexpression in CD40-Activated Human B Lymphocytes. Blood. 110: 3868-3868
Gilbert C, Bergeron M, Méthot S, et al. (2005) Statins could be used to control replication of some viruses, including HIV-1. Viral Immunology. 18: 474-89
Giguere JF, Diou J, Madrenas J, et al. (2005) Virus attachment and replication are promoted after acquisition of host CD28 and CD152 by HIV-1. The Journal of Infectious Diseases. 192: 1265-8
Roy J, Martin G, Giguère JF, et al. (2005) HIV type 1 can act as an APC upon acquisition from the host cell of peptide-loaded HLA-DR and CD86 molecules. Journal of Immunology (Baltimore, Md. : 1950). 174: 4779-88
Giguère JF, Tremblay MJ. (2004) Statin compounds reduce human immunodeficiency virus type 1 replication by preventing the interaction between virion-associated host intercellular adhesion molecule 1 and its natural cell surface ligand LFA-1. Journal of Virology. 78: 12062-5
Bounou S, Giguere JF, Cantin R, et al. (2004) The importance of virus-associated host ICAM-1 in human immunodeficiency virus type 1 dissemination depends on the cellular context. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 1294-6
Giguère JF, Bounou S, Paquette JS, et al. (2004) Insertion of host-derived costimulatory molecules CD80 (B7.1) and CD86 (B7.2) into human immunodeficiency virus type 1 affects the virus life cycle. Journal of Virology. 78: 6222-32
Giguère JF, Paquette JS, Bounou S, et al. (2002) New insights into the functionality of a virion-anchored host cell membrane protein: CD28 versus HIV type 1. Journal of Immunology (Baltimore, Md. : 1950). 169: 2762-71
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