Juan I. Sbodio, Ph.D.

2009 Johns Hopkins University, Baltimore, MD 
Cell Biology
"Juan Sbodio"


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Carolyn Machamer grad student 2009 Johns Hopkins
 (Protein -protein interactions at the Golgi complex and their roles in apoptosis and mitosis.)
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Ahmed I, Sbodio JI, Harraz MM, et al. (2015) Huntington's disease: Neural dysfunction linked to inositol polyphosphate multikinase Proceedings of the National Academy of Sciences of the United States of America. 112: 9751-9756
Paul BD, Sbodio JI, Xu R, et al. (2014) Cystathionine γ-lyase deficiency mediates neurodegeneration in Huntington's disease. Nature. 509: 96-100
Sbodio JI, Paul BD, Machamer CE, et al. (2013) Golgi protein ACBD3 mediates neurotoxicity associated with Huntington's disease. Cell Reports. 4: 890-7
Sbodio JI, Machamer CE. (2007) Identification of a redox-sensitive cysteine in GCP60 that regulates its interaction with golgin-160. The Journal of Biological Chemistry. 282: 29874-81
Yeh TY, Sbodio JI, Tsun ZY, et al. (2007) Insulin-stimulated exocytosis of GLUT4 is enhanced by IRAP and its partner tankyrase. The Biochemical Journal. 402: 279-90
Yeh TY, Sbodio JI, Chi NW. (2006) Mitotic phosphorylation of tankyrase, a PARP that promotes spindle assembly, by GSK3. Biochemical and Biophysical Research Communications. 350: 574-9
Sbodio JI, Hicks SW, Simon D, et al. (2006) GCP60 preferentially interacts with a caspase-generated golgin-160 fragment. The Journal of Biological Chemistry. 281: 27924-31
Yeh TY, Sbodio JI, Nguyen MT, et al. (2005) Tankyrase-1 overexpression reduces genotoxin-induced cell death by inhibiting PARP1. Molecular and Cellular Biochemistry. 276: 183-92
Nguyen MT, Satoh H, Favelyukis S, et al. (2005) JNK and tumor necrosis factor-alpha mediate free fatty acid-induced insulin resistance in 3T3-L1 adipocytes. The Journal of Biological Chemistry. 280: 35361-71
Deng Z, Atanasiu C, Zhao K, et al. (2005) Inhibition of Epstein-Barr virus OriP function by tankyrase, a telomere-associated poly-ADP ribose polymerase that binds and modifies EBNA1. Journal of Virology. 79: 4640-50
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