Jelena S. Bezbradica, Ph.D.
Affiliations: | 2003-2007 | Microbiology and Immunology | Vanderbilt University, Nashville, TN |
| 2007-2013 | Immunobiology | Yale University, New Haven, CT | |
| 2014-2016 | IMB | Queensland University, Saint Lucia, Queensland, Australia | |
| 2016- | Kennedy Institute | University of Oxford, Oxford, United Kingdom |
Area:
ImmunologyWebsite:
https://www.kennedy.ox.ac.uk/research/research-groups/innate-immunity-and-inflammationGoogle:
"https://scholar.google.com/citations?user=oouz2j4AAAAJ&hl=en"Bio:
I earned my Ph.D. degree with Professor Sebastian Joyce at Vanderbilt University, USA. I continued my research training as a Damon Runyon Cancer Research Foundation and Howard Hughes Medical Institute postdoctoral fellow with Professor Ruslan Medzhitov at Yale University, USA, and with Professor Kate Schroder at The University of Queensland, Australia. I joined the Kennedy Institute at University of Oxford in 2016.
Parents
Sign in to add mentor| Sebastian Joyce | grad student | 2007 | Vanderbilt (Microtree) | |
| (Lineage commitment and functional differentiation of invariant natural T (iNKT) cells.) | ||||
| Ruslan Medzhitov | post-doc | 2007-2013 | Yale (Chemistry Tree) | |
| (postdoc) | ||||
Children
Sign in to add trainee| Madelon ME de Jong | post-doc | 2023- | Kennedy institute of Rheumatology (Neurotree) |
BETA: Related publications
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Publications
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| Bezbradica JS, Bryant CE. (2023) Inflammasomes as regulators of mechano-immunity. Embo Reports |
| Danielli S, Ma Z, Pantazi E, et al. (2023) The ion channel CALHM6 controls bacterial infection-induced cellular cross-talk at the immunological synapse. The Embo Journal. e111450 |
| Bezbradica JS, Coll RC, Boucher D. (2022) Activation of the Non-canonical Inflammasome in Mouse and Human Cells. Methods in Molecular Biology (Clifton, N.J.). 2459: 51-63 |
| Lee MSJ, Inoue T, Ise W, et al. (2022) B cell-intrinsic TBK1 is essential for germinal center formation during infection and vaccination in mice. The Journal of Experimental Medicine. 219 |
| Fischer FA, Mies LFM, Nizami S, et al. (2021) TBK1 and IKKε act like an OFF switch to limit NLRP3 inflammasome pathway activation. Proceedings of the National Academy of Sciences of the United States of America. 118 |
| Kumar A, Hill TM, Gordy LE, et al. (2020) Nur77 controls tolerance induction, terminal differentiation, and effector functions in semi-invariant natural killer T cells. Proceedings of the National Academy of Sciences of the United States of America |
| McFie M, Koneva L, Collins I, et al. (2020) Ciliary proteins specify the cell inflammatory response by tuning NFκB signaling, independently of primary cilia. Journal of Cell Science |
| Bezbradica JS, Joyce S. (2020) NKT Cells Join the Two Step for Inflammasome-Independent IL-1β Release. Cell Reports. 31: 107481 |
| Monteleone M, Stanley AC, Chen KW, et al. (2018) Interleukin-1β Maturation Triggers Its Relocation to the Plasma Membrane for Gasdermin-D-Dependent and -Independent Secretion. Cell Reports. 24: 1425-1433 |
| Chen KW, Lawlor KE, von Pein JB, et al. (2018) Cutting Edge: Blockade of Inhibitor of Apoptosis Proteins Sensitizes Neutrophils to TNF- but Not Lipopolysaccharide-Mediated Cell Death and IL-1β Secretion. Journal of Immunology (Baltimore, Md. : 1950) |