Sharmistha Ghosh, Ph.D.

Affiliations: 
2004 Louisiana State University, Baton Rouge, LA, United States 
Area:
Molecular Biology
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"Sharmistha Ghosh"

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Anne Grove grad student 2004 Louisiana State
 (DNA binding properties of histone -like protein HU from Deinococcus radiodurans suggest involvement in DNA recombination.)
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Publications

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Lengsfeld BM, Berry KN, Ghosh S, et al. (2012) A Polycomb complex remains bound through DNA replication in the absence of other eukaryotic proteins. Scientific Reports. 2: 661
Satapathy AK, Kulczyk AW, Ghosh S, et al. (2011) Coupling dTTP hydrolysis with DNA unwinding by the DNA helicase of bacteriophage T7. The Journal of Biological Chemistry. 286: 34468-78
Ghosh S, Hamdan SM, Richardson CC. (2010) Two modes of interaction of the single-stranded DNA-binding protein of bacteriophage T7 with the DNA polymerase-thioredoxin complex. The Journal of Biological Chemistry. 285: 18103-12
Ghosh S, Marintcheva B, Takahashi M, et al. (2009) C-terminal phenylalanine of bacteriophage T7 single-stranded DNA-binding protein is essential for strand displacement synthesis by T7 DNA polymerase at a nick in DNA. The Journal of Biological Chemistry. 284: 30339-49
Ghosh S, Hamdan SM, Cook TE, et al. (2008) Interactions of Escherichia coli thioredoxin, the processivity factor, with bacteriophage T7 DNA polymerase and helicase. The Journal of Biological Chemistry. 283: 32077-84
Ghosh S, Hamdan SM, Richardson CC. (2007) Interaction of Escherichia coli Thioredoxin with the Bacteriophage T7 Polymerase, Helicase/Primase at the Replication Fork The Faseb Journal. 21
Ghosh S, Grove A. (2006) The Deinococcus radiodurans-encoded HU protein has two DNA-binding domains. Biochemistry. 45: 1723-33
Chen C, Ghosh S, Grove A. (2004) Substrate specificity of Helicobacter pylori histone-like HU protein is determined by insufficient stabilization of DNA flexure points. The Biochemical Journal. 383: 343-51
Ghosh S, Grove A. (2004) Histone-like protein HU from Deinococcus radiodurans binds preferentially to four-way DNA junctions. Journal of Molecular Biology. 337: 561-71
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