Melina A. Agosto, Ph.D.

Affiliations: 
2008 Harvard University, Cambridge, MA, United States 
Area:
Virology Biology, Microbiology Biology
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"Melina Agosto"

Parents

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Max L. Nibert grad student 2008 Harvard
 (Reovirus outer-capsid disassembly and the mechanism of membrane penetration.)
Theodore G. Wensel post-doc 2008-2015 Baylor College of Medicine (Chemistry Tree)
 (Currently Faculty Member, Baylor College of Medicine)
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Publications

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Moye AR, Robichaux MA, Agosto MA, et al. (2025) Ciliopathy-associated protein, CEP290, is required for ciliary necklace and outer segment membrane formation in retinal photoreceptors. Biorxiv : the Preprint Server For Biology
Haggerty KN, Eshelman SC, Sexton LA, et al. (2024) Super-resolution mapping in rod photoreceptors identifies rhodopsin trafficking through the inner segment plasma membrane as an essential subcellular pathway. Plos Biology. 22: e3002467
Zhang Z, Moye AR, He F, et al. (2024) Centriole and transition zone structures in photoreceptor cilia revealed by cryo-electron tomography. Life Science Alliance. 7
Konecki DM, Hamrick S, Wang C, et al. (2023) CovET: A Covariation-Evolutionary Trace method that Identifies Protein Structure-Function Modules. The Journal of Biological Chemistry. 104896
Haggerty KN, Eshelman SC, Sexton LA, et al. (2023) Mapping rhodopsin trafficking in rod photoreceptors with quantitative super-resolution microscopy. Biorxiv : the Preprint Server For Biology
Huh E, Agosto MA, Wensel TG, et al. (2023) Co-evolutionary Signals in Metabotropic Glutamate Receptors Capture Residue Contacts and Long-Range Functional Interactions. The Journal of Biological Chemistry. 103030
Huh E, Gallion J, Agosto MA, et al. (2021) Recurrent high-impact mutations at cognate structural positions in class A G protein-coupled receptors expressed in tumors. Proceedings of the National Academy of Sciences of the United States of America. 118
Agosto MA, Adeosun AAR, Kumar N, et al. (2021) The mGluR6 ligand-binding domain, but not the C-terminal domain, is required for synaptic localization in retinal ON-bipolar cells. The Journal of Biological Chemistry. 101418
Agosto MA, Wensel TG. (2020) LRRTM4 is a member of the transsynaptic complex between rod photoreceptors and bipolar cells. The Journal of Comparative Neurology
Terrón-Díaz ME, Wright SJ, Agosto MA, et al. (2019) Residues and residue pairs of evolutionary importance differentially direct signaling bias of D2 dopamine receptors. The Journal of Biological Chemistry
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