Evan M. Cale, Ph.D.
Affiliations: | 2011 | Harvard University, Cambridge, MA, United States |
Area:
ImmunologyGoogle:
"Evan Cale"Parents
Sign in to add mentor| Norman Letvin | grad student | 2011 | Harvard | |
| (Mechanisms used by simian immunodeficiency viruses to evade virus-specific CD8-positive T lymphocyte responses.) | ||||
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Publications
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| Cale EM, Shen CH, Olia AS, et al. (2024) A multidonor class of highly glycan-dependent HIV-1 gp120-gp41 interface-targeting broadly neutralizing antibodies. Cell Reports. 43: 115010 |
| Casazza JP, Cale EM, Narpala S, et al. (2022) Safety and tolerability of AAV8 delivery of a broadly neutralizing antibody in adults living with HIV: a phase 1, dose-escalation trial. Nature Medicine |
| Crooks ET, Almanza F, D'Addabbo A, et al. (2021) Engineering well-expressed, V2-immunofocusing HIV-1 envelope glycoprotein membrane trimers for use in heterologous prime-boost vaccine regimens. Plos Pathogens. 17: e1009807 |
| Simonich C, Shipley MM, Doepker L, et al. (2021) A diverse collection of B cells responded to HIV infection in infant BG505. Cell Reports. Medicine. 2: 100314 |
| Cale EM, Bai H, Bose M, et al. (2020) Neutralizing antibody VRC01 failed to select for HIV-1 mutations upon viral rebound. The Journal of Clinical Investigation |
| Krebs SJ, Kwon YD, Schramm CA, et al. (2019) Longitudinal Analysis Reveals Early Development of Three MPER-Directed Neutralizing Antibody Lineages from an HIV-1-Infected Individual. Immunity |
| Crooks ET, Grimley SL, Cully M, et al. (2018) Glycoengineering HIV-1 Env creates 'supercharged' and 'hybrid' glycans to increase neutralizing antibody potency, breadth and saturation. Plos Pathogens. 14: e1007024 |
| Cale EM, Gorman J, Radakovich NA, et al. (2017) Virus-like Particles Identify an HIV V1V2 Apex-Binding Neutralizing Antibody that Lacks a Protruding Loop. Immunity. 46: 777-791.e10 |
| Alam SM, Aussedat B, Vohra Y, et al. (2017) Mimicry of an HIV broadly neutralizing antibody epitope with a synthetic glycopeptide. Science Translational Medicine. 9 |
| Kong R, Xu K, Zhou T, et al. (2016) Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody. Science (New York, N.Y.). 352: 828-33 |