Evan M. Cale, Ph.D.

Affiliations: 
2011 Harvard University, Cambridge, MA, United States 
Area:
Immunology
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"Evan Cale"

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Norman Letvin grad student 2011 Harvard
 (Mechanisms used by simian immunodeficiency viruses to evade virus-specific CD8-positive T lymphocyte responses.)
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Publications

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Krebs SJ, Kwon YD, Schramm CA, et al. (2019) Longitudinal Analysis Reveals Early Development of Three MPER-Directed Neutralizing Antibody Lineages from an HIV-1-Infected Individual. Immunity
Alam SM, Aussedat B, Vohra Y, et al. (2017) Mimicry of an HIV broadly neutralizing antibody epitope with a synthetic glycopeptide. Science Translational Medicine. 9
Kong R, Xu K, Zhou T, et al. (2016) Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody. Science (New York, N.Y.). 352: 828-33
Doria-Rose NA, Bhiman JN, Roark RS, et al. (2015) A new member of the V1V2-directed CAP256-VRC26 lineage that shows increased breadth and exceptional potency. Journal of Virology
Cale EM, Bazick HS, Rianprakaisang TA, et al. (2011) Mutations in a dominant Nef epitope of simian immunodeficiency virus diminish TCR:epitope peptide affinity but not epitope peptide:MHC class I binding. Journal of Immunology (Baltimore, Md. : 1950). 187: 3300-13
Hulot SL, Cale EM, Korber BT, et al. (2011) Vaccine-induced CD8+ T lymphocytes of rhesus monkeys recognize variant forms of an HIV epitope but do not mediate optimal functional activity. Journal of Immunology (Baltimore, Md. : 1950). 186: 5663-74
Cale EM, Hraber P, Giorgi EE, et al. (2011) Epitope-specific CD8+ T lymphocytes cross-recognize mutant simian immunodeficiency virus (SIV) sequences but fail to contain very early evolution and eventual fixation of epitope escape mutations during SIV infection. Journal of Virology. 85: 3746-57
Yeh WW, Cale EM, Jaru-Ampornpan P, et al. (2006) Compensatory substitutions restore normal core assembly in simian immunodeficiency virus isolates with Gag epitope cytotoxic T-lymphocyte escape mutations. Journal of Virology. 80: 8168-77
Eisen-Vandervelde AL, Waggoner SN, Yao ZQ, et al. (2004) Hepatitis C virus core selectively suppresses interleukin-12 synthesis in human macrophages by interfering with AP-1 activation. The Journal of Biological Chemistry. 279: 43479-86
Yao ZQ, Eisen-Vandervelde A, Waggoner SN, et al. (2004) Direct binding of hepatitis C virus core to gC1qR on CD4+ and CD8+ T cells leads to impaired activation of Lck and Akt. Journal of Virology. 78: 6409-19
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