Nathalie Y. Agar, Ph.D.

Affiliations: 
2002 Concordia University (Canada), Montreal, QC, Canada 
Area:
Biochemistry
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"Nathalie Agar"
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Parents

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Justin B. Powlowski grad student 2002 Concordia University Montreal
 (Identification of molecular determinants of substrate specificity and activity for biphenyl dioxygenase from Comamonas testosteroni B-356.)
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Publications

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Sun Y, Alberta JA, Pilarz C, et al. (2017) A brain-penetrant RAF dimer antagonist for the noncanonical BRAF oncoprotein of pediatric low-grade astrocytomas. Neuro-Oncology
Sarkaria JN, Calligaris D, Ma D, et al. (2016) Abstract B25: The critical importance of the blood-brain barrier in modulating the response to otherwise highly effective targeted therapies in patient-derived orthotopic glioblastoma xenografts Clinical Cancer Research. 22
Kieran MW, Sun Y, Pilarz C, et al. (2016) LG-47TYPE II RAF INHIBITORS INHIBIT BRAF MUTATIONS AND TRUNCATED FUSIONS IN PEDIATRIC LOW-GRADE GLIOMAS Neuro-Oncology. 18: iii89.2-iii89
Ma D, Calligaris D, Zhang S, et al. (2015) DDEL-15MANIPULATION OF THE BLOOD-BRAIN-BARRIER RESTORES THE EFFICACY OF MDM2 INHIBITION IN ORTHOTOPIC GLIOBLASTOMA MODELS Neuro-Oncology. 17: v76.3-v76
Jonas O, Sengupta S, Calligaris D, et al. (2014) ET-24 * A NOVEL TROJAN HORSE FOR IN-VIVO SENSITIVITY TESTING OF MEDULLOBLASTOMA THERAPIES Neuro-Oncology. 16: v84-v84
Colbert CL, Agar NY, Kumar P, et al. (2013) Structural characterization of Pandoraea pnomenusa B-356 biphenyl dioxygenase reveals features of potent polychlorinated biphenyl-degrading enzymes. Plos One. 8: e52550
Master ER, Agar NY, Gómez-Gil L, et al. (2008) Biphenyl dioxygenase from an arctic isolate is not cold adapted. Applied and Environmental Microbiology. 74: 3908-11
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