Mark J. Osborn, Ph.D.

Affiliations: 
2009 Microbiology, Immunology and Cancer Biology University of Minnesota, Twin Cities, Minneapolis, MN 
Area:
Genetics
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"Mark Osborn"

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Bruce R. Blazar grad student 2009 UMN
 (Gene therapy strategies for targeting the treatment refractory sites in Hurler syndrome.)
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Publications

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Webber BR, Lonetree CL, Kluesner MG, et al. (2019) Author Correction: Highly efficient multiplex human T cell engineering without double-strand breaks using Cas9 base editors. Nature Communications. 10: 5659
Kang E, Kim YM, Seo GH, et al. (2019) Phenotype categorization of neurofibromatosis type I and correlation to NF1 mutation types. Journal of Human Genetics
Webber BR, Lonetree CL, Kluesner MG, et al. (2019) Highly efficient multiplex human T cell engineering without double-strand breaks using Cas9 base editors. Nature Communications. 10: 5222
Kim YM, Yum MS, Heo SH, et al. (2019) Pharmacologic properties of high-dose ambroxol in four patients with Gaucher disease and myoclonic epilepsy. Journal of Medical Genetics
Saha A, Taylor PA, Lees CJ, et al. (2019) Donor and host B7-H4 expression negatively regulates acute graft-versus-host disease lethality. Jci Insight. 4
Osborn MJ, Newby GA, McElroy AN, et al. (2019) Base editor correction of COL7A1 in recessive dystrophic epidermolysis bullosa patient-derived fibroblasts and iPSCs. The Journal of Investigative Dermatology
McDonald-Hyman C, Muller JT, Loschi M, et al. (2018) The vimentin intermediate filament network restrains regulatory T-cell suppression of graft-versus-host disease. The Journal of Clinical Investigation
Pennell CA, Barnum JL, McDonald-Hyman CS, et al. (2018) Human CD19-Targeted Mouse T Cells Induce B Cell Aplasia and Toxicity in Human CD19 Transgenic Mice. Molecular Therapy : the Journal of the American Society of Gene Therapy
Vanden Oever M, Twaroski K, Osborn MJ, et al. (2018) Inside out: regenerative medicine for recessive dystrophic epidermolysis bullosa. Pediatric Research. 83: 318-324
Osborn MJ, Lees CJ, McElroy AN, et al. (2018) CRISPR/Cas9-Based Cellular Engineering for Targeted Gene Overexpression. International Journal of Molecular Sciences. 19
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