Mark J. Osborn, Ph.D.

Affiliations: 
2009 Microbiology, Immunology and Cancer Biology University of Minnesota, Twin Cities, Minneapolis, MN 
Area:
Genetics
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"Mark Osborn"

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Bruce R. Blazar grad student 2009 UMN
 (Gene therapy strategies for targeting the treatment refractory sites in Hurler syndrome.)
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Publications

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Saha A, Palchaudhuri R, Lanieri L, et al. (2024) Alloengraftment without significant toxicity or GVHD in CD45 antibody-drug conjugate conditioned Fanconi anemia mice. Blood
Feser CJ, Williams JM, Lammers DT, et al. (2023) Engineering Human Cells Expressing CRISPR/Cas9-Synergistic Activation Mediators for Recombinant Protein Production. International Journal of Molecular Sciences. 24
Larson JH, Jin S, Loschi M, et al. (2023) Enforced gut homing of murine regulatory T cells reduces early graft-versus-host disease severity. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Pennell CA, Campbell H, Storlie MD, et al. (2022) Human CD19-specific switchable CAR T-cells are efficacious as constitutively active CAR T-cells but cause less morbidity in a mouse model of human CD19 malignancy. Journal For Immunotherapy of Cancer. 10
Neugebauer ME, Hsu A, Arbab M, et al. (2022) Evolution of an adenine base editor into a small, efficient cytosine base editor with low off-target activity. Nature Biotechnology
Sipe CJ, Kluesner MG, Bingea SP, et al. (2022) Correction of Fanconi Anemia Mutations Using Digital Genome Engineering. International Journal of Molecular Sciences. 23
Bolivar-Wagers S, Loschi ML, Jin S, et al. (2022) Murine CAR19 Tregs suppress acute graft-versus-host disease and maintain graft-versus-tumor responses. Jci Insight
Meyer-Mueller C, Osborn MJ, Tolar J, et al. (2022) Revertant Mosaicism in Epidermolysis Bullosa. Biomedicines. 10
Knipping F, Newby GA, Eide CR, et al. (2021) Disruption of HIV-1 co-receptors CCR5 and CXCR4in primary human T cells and hematopoietic stemand progenitor cells using base editing. Molecular Therapy : the Journal of the American Society of Gene Therapy
Hippen KL, Furlan SN, Roychoudhuri R, et al. (2021) Multiply restimulated human thymic regulatory T cells express distinct signature regulatory T-cell transcription factors without evidence of exhaustion. Cytotherapy
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