Sehoon Keum, Ph.D.

Affiliations: 
2010 Genetics and Genomics Duke University, Durham, NC 
Area:
Genetics
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"Sehoon Keum"

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Douglas Marchuk grad student 2010 Duke
 (Genetic modifiers in response to ischemia.)
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Publications

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McClung JM, McCord TJ, Ryan TE, et al. (2017) A BAG3 Coding Variant in Mice Determines Susceptibility to Ischemic Limb Muscle Myopathy by Directing Autophagy. Circulation
Lee HK, Keum S, Sheng H, et al. (2016) Natural allelic variation of the IL-21 receptor modulates ischemic stroke infarct volume. The Journal of Clinical Investigation
Keum S, Park J, Kim A, et al. (2015) Variability in empathic fear response among eleven inbred strains of mice. Genes, Brain, and Behavior
Keum S, Lee HK, Chu PL, et al. (2013) Natural genetic variation of integrin alpha L (Itgal) modulates ischemic brain injury in stroke. Plos Genetics. 9: e1003807
Chu PL, Keum S, Marchuk DA. (2013) A novel genetic locus modulates infarct volume independently of the extent of collateral circulation. Physiological Genomics. 45: 751-63
McClung JM, McCord TJ, Keum S, et al. (2012) Skeletal muscle-specific genetic determinants contribute to the differential strain-dependent effects of hindlimb ischemia in mice. The American Journal of Pathology. 180: 2156-69
Ahn SH, Deshmukh H, Johnson N, et al. (2010) Two genes on A/J chromosome 18 are associated with susceptibility to Staphylococcus aureus infection by combined microarray and QTL analyses. Plos Pathogens. 6: e1001088
Keum S, Marchuk DA. (2009) A locus mapping to mouse chromosome 7 determines infarct volume in a mouse model of ischemic stroke. Circulation. Cardiovascular Genetics. 2: 591-8
Zhang H, Keum S, Marchuk D, et al. (2009) Analysis of 19 mouse strains demonstrates that genetic variations in pial collateral dimensions are the major determinants of severity of infarct volume after middle cerebral artery occlusion (MCAO) Cardiovascular Revascularization Medicine. 10: 273-274
Dokun AO, Keum S, Hazarika S, et al. (2008) A quantitative trait locus (LSq-1) on mouse chromosome 7 is linked to the absence of tissue loss after surgical hindlimb ischemia. Circulation. 117: 1207-15
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