John D. Lich, Ph.D.
Affiliations: | 2000 | Indiana University, Bloomington, Bloomington, IN, United States |
Area:
ImmunologyGoogle:
"John Lich"Parents
Sign in to add mentor| Janice S. Blum | grad student | 2000 | Indiana University Bloomington | |
| (MHC class II-restricted presentation of exogenous and cytoplasmic glutamate decarboxylase.) | ||||
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Publications
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| Harris PA, Marinis JM, Lich JD, et al. (2019) Identification of a RIP1 Kinase Inhibitor Clinical Candidate (GSK3145095) for the Treatment of Pancreatic Cancer. Acs Medicinal Chemistry Letters. 10: 857-862 |
| Wang W, Marinis JM, Beal AM, et al. (2018) RIP1 Kinase Drives Macrophage-Mediated Adaptive Immune Tolerance in Pancreatic Cancer. Cancer Cell. 34: 757-774.e7 |
| Finger JN, Brusq JM, Campobasso N, et al. (2017) Identification of an antibody-based immunoassay for measuring direct target binding of RIPK1 inhibitors in cells and tissues. Pharmacology Research & Perspectives. 5 |
| Harris PA, Berger SB, Jeong JU, et al. (2017) Discovery of a First-in-Class Receptor Interacting Protein 1 (RIP1) Kinase Specific Clinical Candidate (GSK2982772) for the Treatment of Inflammatory Diseases. Journal of Medicinal Chemistry |
| Harris PA, Bandyopadhyay D, Berger SB, et al. (2013) Discovery of Small Molecule RIP1 Kinase Inhibitors for the Treatment of Pathologies Associated with Necroptosis. Acs Medicinal Chemistry Letters. 4: 1238-43 |
| Finger JN, Lich JD, Dare LC, et al. (2012) Autolytic proteolysis within the function to find domain (FIIND) is required for NLRP1 inflammasome activity. The Journal of Biological Chemistry. 287: 25030-7 |
| Allen IC, Lich JD, Arthur JC, et al. (2012) Characterization of NLRP12 during the development of allergic airway disease in mice. Plos One. 7: e30612 |
| Arthur JC, Lich JD, Ye Z, et al. (2010) Cutting edge: NLRP12 controls dendritic and myeloid cell migration to affect contact hypersensitivity. Journal of Immunology (Baltimore, Md. : 1950). 185: 4515-9 |
| O'Connor BP, Eun SY, Ye Z, et al. (2008) Semaphorin 6D regulates the late phase of CD4+ T cell primary immune responses. Proceedings of the National Academy of Sciences of the United States of America. 105: 13015-20 |
| Arthur JC, Lich JD, Aziz RK, et al. (2007) Heat shock protein 90 associates with monarch-1 and regulates its ability to promote degradation of NF-kappaB-inducing kinase. Journal of Immunology (Baltimore, Md. : 1950). 179: 6291-6 |