Xikui Liu, Ph.D.

Affiliations: 
2005 State University of New York, Buffalo, Buffalo, NY, United States 
Area:
Immunology, Cell Biology
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"Xikui Liu"

Parents

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Sarah L. Gaffen grad student 2005 SUNY Buffalo
 (Interleukin -17 gene regulation in T cells.)
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Publications

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Liu X, Zawidzka EM, Li H, et al. (2019) RORγ agonists enhance the sustained antitumor activity through intrinsic Tc17 cytotoxicity and Tc1 recruitment. Cancer Immunology Research
Hu X, Majchrzak K, Liu X, et al. (2018) In vitro priming of adoptively transferred T cells with a RORγ agonist confers durable memory and stemness in vivo. Cancer Research
Hu X, Liu X, Li H, et al. (2018) Novel small-molecule RORγ agonist immuno-oncology agent LYC-55716: Tumor selection and evaluation of renal cell and bladder cancer for inclusion in phase 2a expansion. Journal of Clinical Oncology. 36: 424-424
Carter L, Liu X, Li H, et al. (2018) RORγ agonist LYC-55716, a novel small molecule immunotherapy: Rationale for clinical evaluation in non-small cell lung cancer based on translational and bioinformatic evaluation. Journal of Clinical Oncology. 36: 171-171
Weems GA, Hu X, Liu X, et al. (2018) Lyc-55716: A novel small-molecule RORγ agonist immuno-oncology agent: Rationale for tumor selection and clinical evaluation of gastric and esophageal carcinoma in phase 2a expansion. Journal of Clinical Oncology. 36: 67-67
Hu X, Liu X, Li H, et al. (2018) Abstract 5566: LYC-55716, a first-in-class RORγ agonist: Rationale and preclinical data to support clinical combinations with established immunotherapies Cancer Research. 78: 5566-5566
Gaur P, Verma V, Nandre R, et al. (2018) Abstract 3773: RORγ agonist enhances antitumor effects of agonist anti-OX40 antibody Cancer Research. 78: 3773-3773
Gaur P, Verma V, Nandre R, et al. (2018) Abstract 3762: Novel RORγt agonist induces antitumor immune effect through enhancement of tumor antigen-specific CD8+ T-cell infiltration into the TME Cancer Research. 78: 3762-3762
Franchi L, Monteleone I, Hao LY, et al. (2017) Inhibiting Oxidative Phosphorylation In Vivo Restrains Th17 Effector Responses and Ameliorates Murine Colitis. Journal of Immunology (Baltimore, Md. : 1950)
Hu X, Liu X, Moisan J, et al. (2016) Synthetic RORγ agonists regulate multiple pathways to enhance antitumor immunity. Oncoimmunology. 5: e1254854
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