Colin M. Exline, Ph.D.

Affiliations: 
2009 Microbiology University of Iowa, Iowa City, IA 
Area:
Microbiology Biology, Virology Biology
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"Colin Exline"

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C Martin Stoltzfus grad student 2009 University of Iowa
 (The positive regulation of HIV-1 Vif mRNA splicing is required for efficient virus replication.)
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Publications

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DiGiusto DL, Cannon PM, Holmes MC, et al. (2016) Preclinical development and qualification of ZFN-mediated CCR5 disruption in human hematopoietic stem/progenitor cells. Molecular Therapy. Methods & Clinical Development. 3: 16067
Stan R, DiGiusto D, Cannon P, et al. (2016) 734. Pre-Clinical Development and Qualification of ZFN-Mediated Disruption of CCR5 in Human Hematopoietic Stem and Progenitor Cells Molecular Therapy. 24: S289-S290
Wang J, Exline CM, DeClercq JJ, et al. (2015) Homology-driven genome editing in hematopoietic stem and progenitor cells using ZFN mRNA and AAV6 donors. Nature Biotechnology
Exline CM, Yang SJ, Haworth KG, et al. (2015) Determinants in HIV-2 Env and tetherin required for functional interaction. Retrovirology. 12: 67
Wang J, Exline CM, DeClercq J, et al. (2015) 478. Highly Efficient Targeted Gene Addition in CD34+ Hematopoietic Stem/Progenitor Cells by Combining ZFN mRNA and AAV6 Donor Delivery Molecular Therapy. 23: S190
Hofer U, Henley JE, Exline CM, et al. (2013) Pre-clinical modeling of CCR5 knockout in human hematopoietic stem cells by zinc finger nucleases using humanized mice. The Journal of Infectious Diseases. 208: S160-4
Lopez LA, Yang SJ, Exline CM, et al. (2012) Anti-tetherin activities of HIV-1 Vpu and Ebola virus glycoprotein do not involve removal of tetherin from lipid rafts. Journal of Virology. 86: 5467-80
Droniou-Bonzom ME, Reignier T, Oldenburg JE, et al. (2011) Substitutions in the glycoprotein (GP) of the Candid#1 vaccine strain of Junin virus increase dependence on human transferrin receptor 1 for entry and destabilize the metastable conformation of GP. Journal of Virology. 85: 13457-62
Yang SJ, Lopez LA, Exline CM, et al. (2011) Lack of adaptation to human tetherin in HIV-1 group O and P. Retrovirology. 8: 78
Hauser H, Lopez LA, Yang SJ, et al. (2011) Correction: HIV-1 Vpu and HIV-2 Env counteract BST-2/tetherin by sequestration in a perinuclear compartment Retrovirology. 85
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