Ting-Wan Lin, Ph.D.

Affiliations: 
2006 University of California, Irvine, Irvine, CA 
Area:
Biochemistry, Molecular Biology
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"Ting-Wan Lin"

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Shiou-Chuan Tsai grad student 2006 UC Irvine
 (Characterization of the carboxyltransferase domain in acyl -CoA carboxylase (ACCase) from Streptomyces coelicolor and Mycobacterium tuberculosis.)
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Publications

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Arabolaza A, Shillito ME, Lin TW, et al. (2010) Crystal structures and mutational analyses of acyl-CoA carboxylase beta subunit of Streptomyces coelicolor. Biochemistry. 49: 7367-76
Kurth DG, Gago GM, de la Iglesia A, et al. (2009) ACCase 6 is the essential acetyl-CoA carboxylase involved in fatty acid and mycolic acid biosynthesis in mycobacteria. Microbiology (Reading, England). 155: 2664-75
Swamidass SJ, Azencott CA, Lin TW, et al. (2009) Influence relevance voting: an accurate and interpretable virtual high throughput screening method. Journal of Chemical Information and Modeling. 49: 756-66
Lin TW, Melgar MM, Kurth D, et al. (2006) Structure-based inhibitor design of AccD5, an essential acyl-CoA carboxylase carboxyltransferase domain of Mycobacterium tuberculosis. Proceedings of the National Academy of Sciences of the United States of America. 103: 3072-7
Lin T, Mitchell D, Pham H, et al. (2005) Engineering the substrate specificity and catalysis from crystal structures of the beta-subunit of Acyl-CoA carboxylase Acta Crystallographica Section a Foundations of Crystallography. 61: c228-c228
Chu HM, Guo RT, Lin TW, et al. (2004) Structures of Selenomonas ruminantium phytase in complex with persulfated phytate: DSP phytase fold and mechanism for sequential substrate hydrolysis. Structure (London, England : 1993). 12: 2015-24
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