Jesus F. Barajas, Ph.D.

Affiliations: 
2015 Biological Sciences University of California, Irvine, Irvine, CA 
Area:
Biochemistry, Molecular Biology
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"Jesus Barajas"

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Shiou-Chuan Tsai grad student 2015 UC Irvine
 (Biochemical and Structural Elucidation of Polyketide Synthase and Non-Ribosomal Peptide Synthetase Enzymes Using Novel Pantetheine Analogues.)
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Publications

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Thompson MG, Blake-Hedges JM, Pereira JH, et al. (2020) An iron (II) dependent oxygenase performs the last missing step of plant lysine catabolism. Nature Communications. 11: 2931
Zargar A, Lal R, Valencia LE, et al. (2020) Chemoinformatic-guided engineering of polyketide synthases. Journal of the American Chemical Society
Blake-Hedges JM, Pereira JH, Cruz-Morales P, et al. (2019) Structural mechanism of regioselectivity in an unusual bacterial acyl-CoA dehydrogenase. Journal of the American Chemical Society
Snoek T, Chaberski EK, Ambri F, et al. (2019) Evolution-guided engineering of small-molecule biosensors. Nucleic Acids Research
Milligan JC, Lee DJ, Jackson DR, et al. (2019) Molecular basis for interactions between an acyl carrier protein and a ketosynthase. Nature Chemical Biology
Barajas JF, McAndrew RP, Thompson MG, et al. (2019) Structural insights into dehydratase substrate selection for the borrelidin and fluvirucin polyketide synthases. Journal of Industrial Microbiology & Biotechnology
Thompson MG, Blake-Hedges JM, Cruz-Morales P, et al. (2019) Massively Parallel Fitness Profiling Reveals Multiple Novel Enzymes in Lysine Metabolism. Mbio. 10
Barajas JF, Zargar A, Pang B, et al. (2018) Biochemical Characterization of β-Amino Acid Incorporation in Fluvirucin B2 Biosynthesis. Chembiochem : a European Journal of Chemical Biology
Barajas JF, Blake-Hedges JM, Bailey CB, et al. (2017) Engineered polyketides: Synergy between protein and host level engineering. Synthetic and Systems Biotechnology. 2: 147-166
Yuzawa S, Bailey CB, Fujii T, et al. (2017) Heterologous Gene Expression of N-terminally truncated variants of LipPks1 Suggests a Functionally Critical Structural Motif in the N-terminus of Modular Polyketide Synthase. Acs Chemical Biology
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