Rajendra Uprety, Ph.D.

Affiliations: 
2013 Chemistry North Carolina State University, Raleigh, NC 
Area:
Biochemistry, Microbiology Biology
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"Rajendra Uprety"

Parents

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Alexander Deiters grad student 2013 NCSU
 (Synthesis of Light-Activated Nucleotides and Unnatural Amino Acids for Biological Applications.)
Alexander Deiters grad student 2008-2013 NCSU
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Publications

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Luo J, Arbely E, Zhang J, et al. (2016) Genetically encoded optical activation of DNA recombination in human cells. Chemical Communications (Cambridge, England)
Hemphill J, Liu Q, Uprety R, et al. (2015) Conditional control of alternative splicing through light-triggered splice-switching oligonucleotides. Journal of the American Chemical Society. 137: 3656-62
Luo J, Uprety R, Naro Y, et al. (2014) Genetically encoded optochemical probes for simultaneous fluorescence reporting and light activation of protein function with two-photon excitation. Journal of the American Chemical Society. 136: 15551-8
Uprety R, Luo J, Liu J, et al. (2014) Genetic encoding of caged cysteine and caged homocysteine in bacterial and mammalian cells Chembiochem. 15: 1793-1799
Engelke H, Chou C, Uprety R, et al. (2014) Control of protein function through optochemical translocation. Acs Synthetic Biology. 3: 731-6
Hemphill J, Govan J, Uprety R, et al. (2014) Site-specific promoter caging enables optochemical gene activation in cells and animals. Journal of the American Chemical Society. 136: 7152-8
Govan JM, Uprety R, Thomas M, et al. (2013) Cellular delivery and photochemical activation of antisense agents through a nucleobase caging strategy. Acs Chemical Biology. 8: 2272-82
Connelly CM, Uprety R, Hemphill J, et al. (2012) Spatiotemporal control of microRNA function using light-activated antagomirs. Molecular Biosystems. 8: 2987-93
Govan JM, Uprety R, Hemphill J, et al. (2012) Regulation of transcription through light-activation and light-deactivation of triplex-forming oligonucleotides in mammalian cells. Acs Chemical Biology. 7: 1247-56
Chou C, Uprety R, Davis L, et al. (2011) Genetically encoding an aliphatic diazirine for protein photocrosslinking Chemical Science. 2: 480-483
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