Catharine L. Smith

Affiliations: 
Chemistry University of Arizona, Tucson, AZ 
Area:
Pharmacology, Molecular Biology
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"Catharine Smith"
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Children

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Erin Brettmann research assistant 2007-2010 (Microtree)
Vineela Kadiyala grad student 2013 University of Arizona
Ana A. Tula-Sanchez grad student 2013 University of Arizona
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Publications

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Havas AP, Tula-Sanchez AA, Steenhoek HM, et al. (2023) Defining cellular responses to HDAC-selective inhibitors reveals that efficient targeting of HDAC3 is required to elicit cytotoxicity and overcome naïve resistance to pan-HDACi in diffuse large B cell lymphoma. Translational Oncology. 39: 101779
Griggs CA, Malm SW, Jaime-Frias R, et al. (2017) Valproic acid disrupts the oscillatory expression of core circadian rhythm transcription factors. Toxicology and Applied Pharmacology. 339: 110-120
Lake AD, Chaput AL, Novak P, et al. (2016) Transcription factor binding site enrichment analysis predicts drivers of altered gene expression in nonalcoholic steatohepatitis. Biochemical Pharmacology
Havas AP, Rodrigues KB, Bhakta A, et al. (2016) Belinostat and Vincristine demonstrate mutually synergistic cytotoxicity associated with mitotic arrest and inhibition of polyploidy in a preclinical model of aggressive diffuse large B cell lymphoma. Cancer Biology & Therapy. 0
Patrick NM, Griggs CA, Icenogle AL, et al. (2016) Class I Lysine Deacetylases Promote Glucocorticoid-induced Transcriptional Repression through Functional Interaction with LSD1. The Journal of Steroid Biochemistry and Molecular Biology
Havas AP, Bhakta A, Rodrigues K, et al. (2016) Abstract 275: Combining low dose microtubule targeting agents with belinostat potentiates cytotoxic response in HDACi resistant diffuse large b-cell lymphoma Cancer Research. 76: 275-275
Dickinson SE, Rusche JJ, Bec SL, et al. (2014) The effect of sulforaphane on histone deacetylase activity in keratinocytes: Differences between in vitro and in vivo analyses. Molecular Carcinogenesis
Kadiyala V, Smith CL. (2014) Minireview: The versatile roles of lysine deacetylases in steroid receptor signaling. Molecular Endocrinology (Baltimore, Md.). 28: 607-21
Tula-Sanchez AA, Havas AP, Alonge PJ, et al. (2013) A model of sensitivity and resistance to histone deacetylase inhibitors in diffuse large B cell lymphoma: Role of cyclin-dependent kinase inhibitors. Cancer Biology & Therapy. 14: 949-61
Kadiyala V, Patrick NM, Mathieu W, et al. (2013) Class I lysine deacetylases facilitate glucocorticoid-induced transcription. The Journal of Biological Chemistry. 288: 28900-12
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