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Jacqueline Sharon

Affiliations: 
Boston University, Boston, MA, United States 
Area:
Microbiology Biology, Immunology
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"Jacqueline Sharon"
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Marly I. Roche Pabon grad student 2009 Boston University
Louis J. Vaickus grad student 2010 Boston University

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Publications

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Lu Z, Rynkiewicz MJ, Yang CY, et al. (2014) Functional and structural characterization of Francisella tularensis O-antigen antibodies at the low end of antigen reactivity. Monoclonal Antibodies in Immunodiagnosis and Immunotherapy. 33: 235-45
Lu Z, Rynkiewicz MJ, Madico G, et al. (2014) B-cell epitopes in GroEL of Francisella tularensis. Plos One. 9: e99847
Lu Z, Perkins HM, Sharon J. (2014) Antibodies to both terminal and internal B-cell epitopes of Francisella tularensis O-polysaccharide produced by patients with tularemia. Clinical and Vaccine Immunology : Cvi. 21: 227-33
Sharon J, Rynkiewicz MJ, Lu Z, et al. (2014) Discovery of protective B-cell epitopes for development of antimicrobial vaccines and antibody therapeutics. Immunology. 142: 1-23
Lu Z, Rynkiewicz MJ, Yang CY, et al. (2013) The binding sites of monoclonal antibodies to the non-reducing end of Francisella tularensis O-antigen accommodate mainly the terminal saccharide. Immunology. 140: 374-89
Rynkiewicz MJ, Lu Z, Hui JH, et al. (2012) Structural analysis of a protective epitope of the Francisella tularensis O-polysaccharide. Biochemistry. 51: 5684-94
Lu Z, Madico G, Roche MI, et al. (2012) Protective B-cell epitopes of Francisella tularensis O-polysaccharide in a mouse model of respiratory tularaemia. Immunology. 136: 352-60
Wang Q, Shi X, Leymarie N, et al. (2011) A typical preparation of Francisella tularensis O-antigen yields a mixture of three types of saccharides. Biochemistry. 50: 10941-50
Roche MI, Lu Z, Hui JH, et al. (2011) Characterization of monoclonal antibodies to terminal and internal O-antigen epitopes of Francisella tularensis lipopolysaccharide. Hybridoma (2005). 30: 19-28
Roche MI, Lu Z, Hui JH, et al. (2008) Monoclonal antibodies identify different antigenic epitopes on the lipopolysaccharide of Francisella tularensis for potential use in immunotherapy of tularemia The Faseb Journal. 22: 499-499
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