Cynthia J. Sakofsky, Ph.D.

Affiliations: 
2011 Biological Sciences University of Cincinnati, Cincinnati, OH 
Area:
Genetics, Microbiology Biology, Molecular Biology
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"Cynthia Sakofsky"

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Dennis Grogan grad student 2011 University of Cincinnati
 (Mechanisms Of Genome Stability In The Hyperthermophilic Archaeon Sulfolobus acidocaldarius.)
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Publications

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Sui Y, Qi L, Zhang K, et al. (2020) Analysis of APOBEC-induced mutations in yeast strains with low levels of replicative DNA polymerases. Proceedings of the National Academy of Sciences of the United States of America
Saini N, Sterling JF, Sakofsky CJ, et al. (2020) Mutation signatures specific to DNA alkylating agents in yeast and cancers. Nucleic Acids Research
Sakofsky CJ, Saini N, Klimczak LJ, et al. (2019) Repair of multiple simultaneous double-strand breaks causes bursts of genome-wide clustered hypermutation. Plos Biology. 17: e3000464
Klein HL, Bačinskaja G, Che J, et al. (2019) Guidelines for DNA recombination and repair studies: Cellular assays of DNA repair pathways. Microbial Cell (Graz, Austria). 6: 1-64
Elango R, Sheng Z, Jackson J, et al. (2017) Break-induced replication promotes formation of lethal joint molecules dissolved by Srs2. Nature Communications. 8: 1790
Sakofsky CJ, Malkova A. (2017) Break induced replication in eukaryotes: mechanisms, functions, and consequences. Critical Reviews in Biochemistry and Molecular Biology. 1-19
Sakofsky CJ, Ayyar S, Deem AK, et al. (2015) Translesion Polymerases Drive Microhomology-Mediated Break-Induced Replication Leading to Complex Chromosomal Rearrangements. Molecular Cell
Segar MW, Sakofsky CJ, Malkova A, et al. (2015) MMBIRFinder: A Tool to Detect Microhomology-Mediated Break-Induced Replication. Ieee/Acm Transactions On Computational Biology and Bioinformatics / Ieee, Acm. 12: 799-806
Sakofsky CJ, Grogan DW. (2015) Lesion-Induced Mutation in the Hyperthermophilic Archaeon Sulfolobus acidocaldarius and Its Avoidance by the Y-Family DNA Polymerase Dbh. Genetics. 201: 513-23
Sakofsky CJ, Roberts SA, Malc E, et al. (2014) Break-induced replication is a source of mutation clusters underlying kataegis. Cell Reports. 7: 1640-8
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