Edmond H. Fischer
Affiliations: | University of Washington, Seattle, Seattle, WA |
Area:
structure and regulation of enzymes, control of cellular processes by hormones and growth factors, role of protein tyrosine phosphatases in signal transduction, cell cycle, and transformationWebsite:
http://www.nobelprize.org/nobel_prizes/medicine/laureates/1992/fischer-bio.htmlGoogle:
"Edmond H. Fischer"Bio:
The Nobel Prize in Physiology or Medicine 1992 was awarded jointly to Edmond H. Fischer and Edwin G. Krebs "for their discoveries concerning reversible protein phosphorylation as a biological regulatory mechanism"
http://www.nasonline.org/member-directory/members/55748.html
http://depts.washington.edu/biowww/pages/faculty-Fischer.shtml
http://www.washington.edu/alumni/columns/march98/fischer.html
Mean distance: 9 | S | N | B | C | P |
Parents
Sign in to add mentor| Kurt Heinrich Meyer | grad student | 1947 | University of Geneva | |
| (La purification et l'isolement de l'alpha-amylase de pancréas) | ||||
Children
Sign in to add trainee| Alvin Markovitz | grad student | 1955 | University of Washington (Microtree) |
| Donald John Graves | grad student | 1959 | University of Washington |
| Jerry Leo Hedrick | post-doc | 1962-1965 | University of Washington (DevTree) |
| Robert S. Adelstein | post-doc | 1966-1968 | University of Washington |
| Philip Cohen | post-doc | 1971 | University of Washington |
Collaborators
Sign in to add collaborator| Kurt Heinrich Meyer | collaborator | 1949-1953 | University of Geneva |
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Publications
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| Fischer EH. (2013) Cellular regulation by protein phosphorylation Biochemical and Biophysical Research Communications. 430: 865-867 |
| Fischer EH. (2011) Biochemistry without boundaries. Nature. 478: S5 |
| Fischer EH. (2010) Phosphorylase and the origin of reversible protein phosphorylation Biological Chemistry. 391: 131-137 |
| Arrow KJ, Axelrod J, Benacerraf B, et al. (2001) Nobel laureates' letter to President Bush. The Washington Post. A02 |
| Fischer EH. (1999) Cell signaling by protein tyrosine phosphorylation. Advances in Enzyme Regulation. 39: 359-69 |
| Fischer EH. (1997) Cellular regulation by protein phosphorylation: a historical overview. Biofactors (Oxford, England). 6: 367-74 |
| Reszka AA, Bulinski JC, Krebs EG, et al. (1997) Mitogen-activated protein kinase/extracellular signal-regulated kinase 2 regulates cytoskeletal organization and chemotaxis via catalytic and microtubule-specific interactions. Molecular Biology of the Cell. 8: 1219-32 |
| Eldar-Finkelman H, Argast GM, Foord O, et al. (1996) Expression and characterization of glycogen synthase kinase-3 mutants and their effect on glycogen synthase activity in intact cells. Proceedings of the National Academy of Sciences of the United States of America. 93: 10228-33 |
| Zhao Z, Tan Z, Diltz CD, et al. (1996) Activation of mitogen-activated protein (MAP) kinase pathway by pervanadate, a potent inhibitor of tyrosine phosphatases. The Journal of Biological Chemistry. 271: 22251-5 |
| Law CL, Sidorenko SP, Chandran KA, et al. (1996) CD22 associates with protein tyrosine phosphatase 1C, Syk, and phospholipase C-gamma(1) upon B cell activation. The Journal of Experimental Medicine. 183: 547-60 |