Clarissa Melo Czekster

Affiliations: 
2015-2018 Chemistry University of St. Andrews, Saint Andrews, Scotland, United Kingdom 
 2018- Biology University of St Andrews, Saint Andrews, Scotland, United Kingdom 
Area:
Biochemistry
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"Clarissa Czekster"
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Parents

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Luiz Augusto Basso grad student 2006-2008 Federal University of Rio Grande do Sul
John  S. Blanchard grad student 2008-2012 Yeshiva University
 (Mechanistic characterization of enzymes involved in tetrahydrofolate biosynthesis in Mycobacterium tuberculosis.)
James H. Naismith post-doc 2015- University of St Andrews
Alanna Schepartz post-doc 2012-2014 Yale
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Publications

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Tang P, Harding CJ, Dickson AL, et al. (2024) Snapshots of the Reaction Coordinate of a Thermophilic 2'-Deoxyribonucleoside/ribonucleoside Transferase. Acs Catalysis. 14: 3090-3102
Simpson MC, Harding CJ, Czekster RM, et al. (2023) Unveiling the Catalytic Mechanism of a Processive Metalloaminopeptidase. Biochemistry. 62: 3188-3205
Harding CJ, Bischoff M, Bergkessel M, et al. (2023) An anti-biofilm cyclic peptide targets a secreted aminopeptidase from P. aeruginosa. Nature Chemical Biology
Fisher G, Pečaver E, Read BJ, et al. (2023) Catalytic Cycle of the Bifunctional Enzyme Phosphoribosyl-ATP Pyrophosphohydrolase/Phosphoribosyl-AMP Cyclohydrolase. Acs Catalysis. 13: 7669-7679
Sutherland E, Harding CJ, Czekster CM. (2022) Active site remodelling of a cyclodipeptide synthase redefines substrate scope. Communications Chemistry. 5: 101
Sweeney P, Galliford A, Kumar A, et al. (2022) Structure, dynamics, and molecular inhibition of the Staphylococcus aureus mA22-tRNA methyltransferase TrmK. The Journal of Biological Chemistry. 102040
Harding CJ, Sutherland E, Hanna JG, et al. (2021) Correction: Bypassing the requirement for aminoacyl-tRNA by a cyclodipeptide synthase enzyme. Rsc Chemical Biology. 2: 942-943
Harding CJ, Sutherland E, Hanna JG, et al. (2021) Bypassing the requirement for aminoacyl-tRNA by a cyclodipeptide synthase enzyme. Rsc Chemical Biology. 2: 230-240
Athukoralage JS, Graham S, Rouillon C, et al. (2020) The dynamic interplay of host and viral enzymes in type III CRISPR-mediated cyclic nucleotide signalling. Elife. 9
Athukoralage JS, Graham S, Rouillon C, et al. (2020) Author response: The dynamic interplay of host and viral enzymes in type III CRISPR-mediated cyclic nucleotide signalling Elife
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