Natalia Frias-Staheli, Ph.D.

2008 Icahn School of Medicine at Mount Sinai, New York, NY, United States 
Microbiology Biology, Virology Biology, Pathology
"Natalia Frias-Staheli"


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Adolfo Garcia-Sastre grad student 2008 Mount Sinai School of Medicine
 (Identification and characterization of the protease activity of the L protein of Crimean-Congo Hemorrhagic fever virus.)
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Vigil A, Frias-Staheli N, Carabeo T, et al. (2020) Airway Delivery of Anti-influenza Monoclonal Antibodies Results in Enhanced Antiviral Activities and Enables Broad-Coverage Combination Therapies. Journal of Virology. 94
Macleod JML, Marmor H, García-Sastre A, et al. (2014) Mapping of the interaction domains of the Crimean-Congo hemorrhagic fever virus nucleocapsid protein. The Journal of General Virology. 96: 524-537
Frias-Staheli N, Dorner M, Marukian S, et al. (2014) Utility of humanized BLT mice for analysis of dengue virus infection and antiviral drug testing. Journal of Virology. 88: 2205-18
van Kasteren PB, Beugeling C, Ninaber DK, et al. (2011) Arterivirus and nairovirus ovarian tumor domain-containing Deubiquitinases target activated RIG-I to control innate immune signaling. Journal of Virology. 86: 773-85
James TW, Frias-Staheli N, Bacik JP, et al. (2011) Structural basis for the removal of ubiquitin and interferon-stimulated gene 15 by a viral ovarian tumor domain-containing protease. Proceedings of the National Academy of Sciences of the United States of America. 108: 2222-7
Taylor SL, Frias-Staheli N, García-Sastre A, et al. (2008) Hantaan virus nucleocapsid protein binds to importin alpha proteins and inhibits tumor necrosis factor alpha-induced activation of nuclear factor kappa B. Journal of Virology. 83: 1271-9
Frias-Staheli N, Giannakopoulos NV, Kikkert M, et al. (2007) Ovarian tumor domain-containing viral proteases evade ubiquitin- and ISG15-dependent innate immune responses. Cell Host & Microbe. 2: 404-16
Lenschow DJ, Lai C, Frias-Staheli N, et al. (2007) IFN-stimulated gene 15 functions as a critical antiviral molecule against influenza, herpes, and Sindbis viruses. Proceedings of the National Academy of Sciences of the United States of America. 104: 1371-6
Bertolotti-Ciarlet A, Smith J, Strecker K, et al. (2005) Cellular localization and antigenic characterization of crimean-congo hemorrhagic fever virus glycoproteins. Journal of Virology. 79: 6152-61
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