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Marian C. Bryan, Ph.D. - Publications

Affiliations: 
2004 Scripps Research Institute, La Jolla, La Jolla, CA, United States 
Area:
organic chemistry
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23 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Rajapaksa NS, Gobbi A, Drobnick J, Do S, Kolesnikov A, Liang J, Chen Y, Sujatha-Bhaskar S, Huang Z, Brightbill H, Francis R, Yu C, Choo EF, DeMent K, Ran Y, ... ... Bryan MC, et al. Discovery of Potent Benzolactam IRAK4 Inhibitors with Robust in Vivo Activity. Acs Medicinal Chemistry Letters. 11: 327-333. PMID 32184965 DOI: 10.1021/Acsmedchemlett.9B00380  0.33
2019 Bryan MC, Drobnick J, Gobbi A, Kolesnikov A, Chen Y, Rajapaksa N, Ndubaku CO, Feng JA, Chang W, Francis R, Yu C, Choo EF, DeMent K, Ran Y, An L, et al. Development of potent and selective pyrazolopyrimidine IRAK4 inhibitors. Journal of Medicinal Chemistry. PMID 31082230 DOI: 10.1021/acs.jmedchem.9b00439  0.356
2018 Bryan MC, Rajapaksa N. Kinase Inhibitors for the Treatment of Immunological Disorders: Recent Advances. Journal of Medicinal Chemistry. PMID 29870256 DOI: 10.1021/Acs.Jmedchem.8B00667  0.326
2017 Aliagas I, Berger R, Goldberg K, Nishimura RT, Reilly J, Richardson PF, Richter DT, Sherer EC, Sparling BA, Bryan MC. Sustainable Practices in Medicinal Chemistry Part 2: Green by Design. Journal of Medicinal Chemistry. PMID 28375009 DOI: 10.1021/Acs.Jmedchem.6B01837  0.313
2016 Chan BK, Hanan EJ, Bowman K, Bryan MC, Burdick DJ, Chan EW, Chen Y, Clausen S, Dela Vega T, Dotson J, Eigenbrot C, Elliott RL, Heald RA, Jackson PS, Knight JD, et al. Discovery of a Non-Covalent, Mutant-Selective Epidermal Growth Factor Receptor Inhibitor. Journal of Medicinal Chemistry. PMID 27564586 DOI: 10.1021/Acs.Jmedchem.6B00995  0.336
2016 Bryan MC, Burdick DJ, Chan BK, Chen Y, Clausen S, Dotson J, Eigenbrot C, Elliott R, Hanan EJ, Heald R, Jackson P, La H, Lainchbury M, Malek S, Mann SE, et al. Pyridones as Highly Selective, Noncovalent Inhibitors of T790M Double Mutants of EGFR. Acs Medicinal Chemistry Letters. 7: 100-4. PMID 26819674 DOI: 10.1021/Acsmedchemlett.5B00428  0.366
2015 Hanan EJ, Baumgardner M, Bryan MC, Chen Y, Eigenbrot C, Fan P, Gu XH, La H, Malek S, Purkey HE, Schaefer G, Schmidt S, Sideris S, Yen I, Yu C, et al. 4-Aminoindazolyl-dihydrofuro[3,4-d]pyrimidines as non-covalent inhibitors of mutant epidermal growth factor receptor tyrosine kinase. Bioorganic & Medicinal Chemistry Letters. PMID 26639762 DOI: 10.1016/J.Bmcl.2015.11.078  0.308
2014 Epstein O, Bryan MC, Cheng AC, Derakhchan K, Dineen TA, Hickman D, Hua Z, Human JB, Kreiman C, Marx IE, Weiss MM, Wahl RC, Wen PH, Whittington DA, Wood S, et al. Lead optimization and modulation of hERG activity in a series of aminooxazoline xanthene β-site amyloid precursor protein cleaving enzyme (BACE1) inhibitors. Journal of Medicinal Chemistry. 57: 9796-810. PMID 25389560 DOI: 10.1021/Jm501266W  0.321
2013 Bryan MC, Hein CD, Gao H, Xia X, Eastwood H, Bruenner BA, Louie SW, Doherty EM. Disubstituted 1-aryl-4-aminopiperidine library synthesis using computational drug design and high-throughput batch and flow technologies. Acs Combinatorial Science. 15: 503-11. PMID 23927004 DOI: 10.1021/Co400078R  0.339
2013 Bryan MC, Falsey JR, Frohn M, Reichelt A, Yao G, Bartberger MD, Bailis JM, Zalameda L, Miguel TS, Doherty EM, Allen JG. N-substituted azaindoles as potent inhibitors of Cdc7 kinase. Bioorganic & Medicinal Chemistry Letters. 23: 2056-60. PMID 23481650 DOI: 10.1016/J.Bmcl.2013.02.007  0.355
2012 Bryan MC, Whittington DA, Doherty EM, Falsey JR, Cheng AC, Emkey R, Brake RL, Lewis RT. Rapid development of piperidine carboxamides as potent and selective anaplastic lymphoma kinase inhibitors. Journal of Medicinal Chemistry. 55: 1698-705. PMID 22263917 DOI: 10.1021/Jm201565S  0.345
2011 Nishimura N, Siegmund A, Liu L, Yang K, Bryan MC, Andrews KL, Bo Y, Booker SK, Caenepeel S, Freeman D, Liao H, McCarter J, Mullady EL, San Miguel T, Subramanian R, et al. Phospshoinositide 3-kinase (PI3K)/mammalian target of rapamycin (mTOR) dual inhibitors: discovery and structure-activity relationships of a series of quinoline and quinoxaline derivatives. Journal of Medicinal Chemistry. 54: 4735-51. PMID 21612232 DOI: 10.1021/Jm200386S  0.333
2004 Blixt O, Head S, Mondala T, Scanlan C, Huflejt ME, Alvarez R, Bryan MC, Fazio F, Calarese D, Stevens J, Razi N, Stevens DJ, Skehel JJ, van Die I, Burton DR, et al. Printed covalent glycan array for ligand profiling of diverse glycan binding proteins. Proceedings of the National Academy of Sciences of the United States of America. 101: 17033-8. PMID 15563589 DOI: 10.1073/Pnas.0407902101  0.471
2004 Hanson S, Best M, Bryan MC, Wong CH. Chemoenzymatic synthesis of oligosaccharides and glycoproteins. Trends in Biochemical Sciences. 29: 656-63. PMID 15544952 DOI: 10.1016/J.Tibs.2004.10.004  0.662
2004 Bryan MC, Fazio F, Lee HK, Huang CY, Chang A, Best MD, Calarese DA, Blixt O, Paulson JC, Burton D, Wilson IA, Wong CH. Covalent display of oligosaccharide arrays in microtiter plates. Journal of the American Chemical Society. 126: 8640-1. PMID 15250702 DOI: 10.1021/Ja048433F  0.657
2004 Bryan MC, Lee LV, Wong CH. High-throughput identification of fucosyltransferase inhibitors using carbohydrate microarrays. Bioorganic & Medicinal Chemistry Letters. 14: 3185-8. PMID 15149672 DOI: 10.1016/J.Bmcl.2004.04.001  0.504
2004 Bryan MC, Wong CH. Aminoglycoside array for the high-throughput analysis of small molecule-RNA interactions Tetrahedron Letters. 45: 3639-3642. DOI: 10.1016/J.Tetlet.2004.03.035  0.496
2004 Fazio F, Bryan MC, Lee HK, Chang A, Wong CH. Assembly of sugars on polystyrene plates: A new facile microarray fabrication technique Tetrahedron Letters. 45: 2689-2692. DOI: 10.1016/J.Tetlet.2004.01.159  0.461
2003 Wong CH, Bryan MC. Sugar arrays in microtiter plates. Methods in Enzymology. 362: 218-25. PMID 12968366 DOI: 10.1016/S0076-6879(03)01015-2  0.522
2003 Chapman E, Bryan MC, Wong CH. Mechanistic studies of beta-arylsulfotransferase IV. Proceedings of the National Academy of Sciences of the United States of America. 100: 910-5. PMID 12547913 DOI: 10.1073/Pnas.0337638100  0.572
2003 Wong CH, Bryan MC, Nyffeler PT, Liu H, Chapman E. Synthesis of carbohydrate-based antibiotics Pure and Applied Chemistry. 75: 179-186. DOI: 10.1351/Pac200375020179  0.572
2002 Fazio F, Bryan MC, Blixt O, Paulson JC, Wong CH. Synthesis of sugar arrays in microtiter plate. Journal of the American Chemical Society. 124: 14397-402. PMID 12452714 DOI: 10.1021/Ja020887U  0.539
2002 Bryan MC, Plettenburg O, Sears P, Rabuka D, Wacowich-Sgarbi S, Wong CH. Saccharide display on microtiter plates. Chemistry & Biology. 9: 713-20. PMID 12079783 DOI: 10.1016/S1074-5521(02)00155-2  0.681
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