Year |
Citation |
Score |
2022 |
Fan M, Lu W, Che J, Kwiatkowski NP, Gao Y, Seo HS, Ficarro SB, Gokhale PC, Liu Y, Geffken EA, Lakhani J, Song K, Kuljanin M, Ji W, Jiang J, et al. Covalent disruptor of YAP-TEAD association suppresses defective hippo signaling. Elife. 11. PMID 36300789 DOI: 10.7554/eLife.78810 |
0.301 |
|
2020 |
Pinch BJ, Doctor ZM, Nabet B, Browne CM, Seo HS, Mohardt ML, Kozono S, Lian X, Manz TD, Chun Y, Kibe S, Zaidman D, Daitchman D, Yeoh ZC, Vangos NE, et al. Identification of a potent and selective covalent Pin1 inhibitor. Nature Chemical Biology. PMID 32483379 DOI: 10.1038/S41589-020-0550-9 |
0.344 |
|
2020 |
Harvey EP, Hauseman ZJ, Cohen DT, Rettenmaier TJ, Lee S, Huhn AJ, Wales TE, Seo HS, Luccarelli J, Newman CE, Guerra RM, Bird GH, Dhe-Paganon S, Engen JR, Wells JA, et al. Identification of a Covalent Molecular Inhibitor of Anti-apoptotic BFL-1 by Disulfide Tethering. Cell Chemical Biology. PMID 32413285 DOI: 10.1016/J.Chembiol.2020.04.004 |
0.399 |
|
2020 |
Ben-Nun Y, Seo HS, Harvey EP, Hauseman ZJ, Wales TE, Newman CE, Cathcart AM, Engen JR, Dhe-Paganon S, Walensky LD. Identification of a Structural Determinant for Selective Targeting of HDMX. Structure (London, England : 1993). PMID 32359398 DOI: 10.1016/J.Str.2020.04.011 |
0.369 |
|
2020 |
Manz TD, Sivakumaren SC, Ferguson FM, Zhang T, Yasgar A, Seo HS, Ficarro SB, Card JD, Shim H, Miduturu CV, Simeonov A, Shen M, Marto JA, Dhe-Paganon S, Hall MD, et al. Discovery and Structure-Activity Relationship Study of (Z)-5-Methylenethiazolidin-4-one Derivatives as Potent and Selective Pan-phosphatidylinositol 5-Phosphate 4-Kinase Inhibitors. Journal of Medicinal Chemistry. PMID 32298120 DOI: 10.1021/Acs.Jmedchem.0C00227 |
0.361 |
|
2020 |
Manz TD, Sivakumaren SC, Yasgar A, Hall MD, Davis MI, Seo HS, Card JD, Ficarro SB, Shim H, Marto JA, Dhe-Paganon S, Sasaki AT, Boxer MB, Simeonov A, Cantley LC, et al. Structure-Activity Relationship Study of Covalent Pan-phosphatidylinositol 5-Phosphate 4-Kinase Inhibitors. Acs Medicinal Chemistry Letters. 11: 346-352. PMID 32184968 DOI: 10.1021/Acsmedchemlett.9B00402 |
0.368 |
|
2020 |
Sivakumaren SC, Shim H, Zhang T, Ferguson FM, Lundquist MR, Browne CM, Seo HS, Paddock MN, Manz TD, Jiang B, Hao MF, Krishnan P, Wang DG, Yang TJ, Kwiatkowski NP, et al. Targeting the PI5P4K Lipid Kinase Family in Cancer Using Covalent Inhibitors. Cell Chemical Biology. PMID 32130941 DOI: 10.1016/J.Chembiol.2020.02.003 |
0.342 |
|
2019 |
Blus BJ, Koh J, Krolak A, Seo HS, Coutavas E, Blobel G. Allosteric modulation of nucleoporin assemblies by intrinsically disordered regions. Science Advances. 5: eaax1836. PMID 31807700 DOI: 10.1126/Sciadv.Aax1836 |
0.362 |
|
2019 |
Valencia AM, Collings CK, Dao HT, St Pierre R, Cheng YC, Huang J, Sun ZY, Seo HS, Mashtalir N, Comstock DE, Bolonduro O, Vangos NE, Yeoh ZC, Dornon MK, Hermawan C, et al. Recurrent SMARCB1 Mutations Reveal a Nucleosome Acidic Patch Interaction Site That Potentiates mSWI/SNF Complex Chromatin Remodeling. Cell. PMID 31759698 DOI: 10.1016/J.Cell.2019.10.044 |
0.388 |
|
2019 |
de Araujo ED, Orlova A, Neubauer HA, Bajusz D, Seo HS, Dhe-Paganon S, Keserű GM, Moriggl R, Gunning PT. Structural Implications of STAT3 and STAT5 SH2 Domain Mutations. Cancers. 11. PMID 31717342 DOI: 10.3390/Cancers11111757 |
0.339 |
|
2019 |
Remillard D, Buckley DL, Seo HS, Ferguson FM, Dhe-Paganon S, Bradner JE, Gray NS. Dual Inhibition of TAF1 and BET Bromodomains from the BI-2536 Kinase Inhibitor Scaffold. Acs Medicinal Chemistry Letters. 10: 1443-1449. PMID 31620231 DOI: 10.1021/Acsmedchemlett.9B00243 |
0.382 |
|
2019 |
Blus BJ, Hashimoto H, Seo HS, Krolak A, Debler EW. Substrate Affinity and Specificity of the ScSth1p Bromodomain Are Fine-Tuned for Versatile Histone Recognition. Structure (London, England : 1993). PMID 31327661 DOI: 10.1016/J.Str.2019.06.009 |
0.388 |
|
2019 |
de Araujo ED, Erdogan F, Neubauer HA, Meneksedag-Erol D, Manaswiyoungkul P, Eram MS, Seo HS, Qadree AK, Israelian J, Orlova A, Suske T, Pham HTT, Boersma A, Tangermann S, Kenner L, et al. Structural and functional consequences of the STAT5B driver mutation. Nature Communications. 10: 2517. PMID 31175292 DOI: 10.1038/S41467-019-10422-7 |
0.314 |
|
2019 |
Pinch B, Doctor Z, Browne CM, Seo H, Nabet B, Kozono S, Lian X, Zaidman D, Daitchman D, London N, Gong L, Manz T, Chun Y, Tan L, Marto J, et al. Abstract 2757: Discovery and characterization of covalent Pin1 inhibitors targeted to an active site cysteine Cancer Research. 79: 2757-2757. DOI: 10.1158/1538-7445.Am2019-2757 |
0.405 |
|
2018 |
Kozono S, Lin YM, Seo HS, Pinch B, Lian X, Qiu C, Herbert MK, Chen CH, Tan L, Gao ZJ, Massefski W, Doctor ZM, Jackson BP, Chen Y, Dhe-Paganon S, et al. Arsenic targets Pin1 and cooperates with retinoic acid to inhibit cancer-driving pathways and tumor-initiating cells. Nature Communications. 9: 3069. PMID 30093655 DOI: 10.1038/S41467-018-05402-2 |
0.348 |
|
2018 |
Gechijian LN, Buckley DL, Lawlor MA, Reyes JM, Paulk J, Ott CJ, Winter GE, Erb MA, Scott TG, Xu M, Seo HS, Dhe-Paganon S, Kwiatkowski NP, Perry JA, Qi J, et al. Functional TRIM24 degrader via conjugation of ineffectual bromodomain and VHL ligands. Nature Chemical Biology. PMID 29507391 DOI: 10.1038/S41589-018-0010-Y |
0.371 |
|
2018 |
Harvey EP, Seo HS, Guerra RM, Bird GH, Dhe-Paganon S, Walensky LD. Crystal Structures of Anti-apoptotic BFL-1 and Its Complex with a Covalent Stapled Peptide Inhibitor. Structure (London, England : 1993). 26: 153-160.e4. PMID 29276033 DOI: 10.1016/J.Str.2017.11.016 |
0.405 |
|
2018 |
Harvey EP, Seo H, Guerra RM, Bird GH, Dhe-Paganon S, Walensky LD. Abstract 1901: Structural basis for selective therapeutic targeting of BFL-1 in cancer by a covalent stapled peptide inhibitor Cancer Research. 78: 1901-1901. DOI: 10.1158/1538-7445.Am2018-1901 |
0.426 |
|
2017 |
Lamberto I, Liu X, Seo HS, Schauer NJ, Iacob RE, Hu W, Das D, Mikhailova T, Weisberg EL, Engen JR, Anderson KC, Chauhan D, Dhe-Paganon S, Buhrlage SJ. Structure-Guided Development of a Potent and Selective Non-covalent Active-Site Inhibitor of USP7. Cell Chemical Biology. PMID 29056421 DOI: 10.1016/J.Chembiol.2017.09.003 |
0.392 |
|
2017 |
Huang HT, Seo HS, Zhang T, Wang Y, Jiang B, Li Q, Buckley DL, Nabet B, Roberts JM, Paulk J, Dastjerdi S, Winter GE, McLauchlan H, Moran J, Bradner JE, et al. MELK is not necessary for the proliferation of basal-like breast cancer cells. Elife. 6. PMID 28926338 DOI: 10.7554/Elife.26693 |
0.354 |
|
2017 |
Remillard D, Buckley DL, Paulk J, Brien GL, Sonnett M, Seo HS, Dastierdi S, Wühr M, Dhe-Paganon S, Armstrong SA, Bradner JE. Degradation of the BAF Complex Factor BRD9 by Heterobifunctional Ligands. Angewandte Chemie (International Ed. in English). PMID 28418626 DOI: 10.1002/Anie.201611281 |
0.406 |
|
2017 |
Erb MA, Scott TG, Li BE, Xie H, Paulk J, Seo HS, Souza A, Roberts JM, Dastjerdi S, Buckley DL, Sanjana NE, Shalem O, Nabet B, Zeid R, Offei-Addo NK, et al. Transcription control by the ENL YEATS domain in acute leukaemia. Nature. PMID 28241139 DOI: 10.1038/Nature21688 |
0.335 |
|
2017 |
Hideshima T, Cottini F, Nozawa Y, Seo HS, Ohguchi H, Samur MK, Cirstea D, Mimura N, Iwasawa Y, Richardson PG, Munshi NC, Chauhan D, Massefski W, Utsugi T, Dhe-Paganon S, et al. p53-related protein kinase confers poor prognosis and represents a novel therapeutic target in multiple myeloma. Blood. PMID 28082445 DOI: 10.1182/Blood-2016-09-738500 |
0.346 |
|
2016 |
Tanaka M, Roberts JM, Seo HS, Souza A, Paulk J, Scott TG, DeAngelo SL, Dhe-Paganon S, Bradner JE. Design and characterization of bivalent BET inhibitors. Nature Chemical Biology. PMID 27775715 DOI: 10.1038/Nchembio.2209 |
0.42 |
|
2014 |
Quan B, Seo HS, Blobel G, Ren Y. Vesiculoviral matrix (M) protein occupies nucleic acid binding site at nucleoporin pair (Rae1 • Nup98). Proceedings of the National Academy of Sciences of the United States of America. 111: 9127-32. PMID 24927547 DOI: 10.1073/Pnas.1409076111 |
0.351 |
|
2013 |
Seo HS, Blus BJ, Jankovic NZ, Blobel G. Structure and nucleic acid binding activity of the nucleoporin Nup157. Proceedings of the National Academy of Sciences of the United States of America. 110: 16450-5. PMID 24062435 DOI: 10.1073/Pnas.1316607110 |
0.354 |
|
2011 |
Yoshida K, Seo HS, Debler EW, Blobel G, Hoelz A. Structural and functional analysis of an essential nucleoporin heterotrimer on the cytoplasmic face of the nuclear pore complex. Proceedings of the National Academy of Sciences of the United States of America. 108: 16571-6. PMID 21930948 DOI: 10.1073/Pnas.1112846108 |
0.432 |
|
2010 |
Ren Y, Seo HS, Blobel G, Hoelz A. Structural and functional analysis of the interaction between the nucleoporin Nup98 and the mRNA export factor Rae1. Proceedings of the National Academy of Sciences of the United States of America. 107: 10406-11. PMID 20498086 DOI: 10.1073/Pnas.1005389107 |
0.399 |
|
2009 |
Seo HS, Ma Y, Debler EW, Wacker D, Kutik S, Blobel G, Hoelz A. Structural and functional analysis of Nup120 suggests ring formation of the Nup84 complex. Proceedings of the National Academy of Sciences of the United States of America. 106: 14281-6. PMID 19706512 DOI: 10.1073/Pnas.0907453106 |
0.362 |
|
2006 |
Seo HS, Abedin S, Kamp D, Wilson DN, Nierhaus KH, Cooperman BS. EF-G-dependent GTPase on the ribosome. conformational change and fusidic acid inhibition. Biochemistry. 45: 2504-14. PMID 16489743 DOI: 10.1021/Bi0516677 |
0.553 |
|
2004 |
Seo HS, Kiel M, Pan D, Raj VS, Kaji A, Cooperman BS. Kinetics and thermodynamics of RRF, EF-G, and thiostrepton interaction on the Escherichia coli ribosome. Biochemistry. 43: 12728-40. PMID 15461445 DOI: 10.1021/Bi048927P |
0.61 |
|
2002 |
Seo HS, Cooperman BS. Large-scale motions within ribosomal 50S subunits as demonstrated using photolabile oligonucleotides. Bioorganic Chemistry. 30: 163-87. PMID 12406702 DOI: 10.1006/Bioo.2002.1255 |
0.572 |
|
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