Phillip S. Hefty, Ph.D. - Publications

Affiliations: 
2001 University of Oklahoma Health Sciences Center, Oklahoma City, OK, United States 
Area:
Microbiology Biology

37/38 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Dimond ZE, Hefty PS. Comprehensive genome analysis and comparisons of the swine pathogen, Chlamydia suis reveals unique ORFs and candidate host-specificity factors. Pathogens and Disease. PMID 32639528 DOI: 10.1093/femspd/ftaa035  0.691
2019 Soules KR, Dmitriev A, LaBrie SD, Dimond ZE, May BH, Johnson DK, Zhang Y, Battaile KP, Lovell S, Hefty PS. Structural and ligand binding analyses of the periplasmic sensor domain of RsbU in Chlamydia trachomatis supports role in TCA cycle regulation. Molecular Microbiology. PMID 31637787 DOI: 10.1111/Mmi.14401  0.705
2019 Suchland RJ, Carrell SJ, Wang Y, Hybiske K, Kim DB, Dimond ZE, Hefty PS, Rockey DD. Chromosomal recombination targets in interspecies lateral gene transfer. Journal of Bacteriology. PMID 31501285 DOI: 10.1128/Jb.00365-19  0.657
2019 Wang Y, LaBrie SD, Carrell SJ, Suchland RJ, Dimond ZE, Kwong F, Rockey DD, Hefty PS, Hybiske K. Development of transposon mutagenesis for . Journal of Bacteriology. PMID 31501283 DOI: 10.1128/Jb.00366-19  0.682
2019 LaBrie SD, Dimond ZE, Harrison KS, Baid S, Wickstrum J, Suchland RJ, Hefty PS. Transposon Mutagenesis in Chlamydia trachomatis Identifies CT339 as a ComEC Homolog Important for DNA Uptake and Lateral Gene Transfer. Mbio. 10. PMID 31387908 DOI: 10.1128/Mbio.01343-19  0.712
2018 Cossé MM, Barta ML, Fisher DJ, Oesterlin LK, Niragire B, Perrinet S, Millot GA, Hefty PS, Subtil A. The Loss of Expression of a Single Type 3 Effector (CT622) Strongly Reduces Infectivity and Growth. Frontiers in Cellular and Infection Microbiology. 8: 145. PMID 29868501 DOI: 10.3389/Fcimb.2018.00145  0.71
2016 Brothwell JA, Muramatsu MK, Toh E, Rockey DD, Putman TE, Barta ML, Hefty PS, Suchland RJ, Nelson DE. Interrogating genes that mediate Chlamydia trachomatis survival in cell culture using conditional mutants and recombination. Journal of Bacteriology. PMID 27246568 DOI: 10.1128/Jb.00161-16  0.692
2015 Tifrea DF, Barta ML, Pal S, Hefty PS, de la Maza LM. Computational modeling of TC0583 as a putative component of the C. muridarum V-type ATP Synthase Complex and assessment of its protective capabilities as a vaccine antigen. Microbes and Infection / Institut Pasteur. PMID 26706820 DOI: 10.1016/J.Micinf.2015.12.002  0.676
2015 Barta ML, Battaile KP, Lovell S, Hefty PS. Hypothetical protein CT398 (CdsZ) interacts with σ(54) (RpoN)-holoenzyme and the type III secretion export apparatus in Chlamydia trachomatis. Protein Science : a Publication of the Protein Society. 24: 1617-32. PMID 26173998 DOI: 10.1002/Pro.2746  0.712
2015 Kemege KE, Hickey JM, Barta ML, Wickstrum J, Balwalli N, Lovell S, Battaile KP, Hefty PS. Chlamydia trachomatis protein CT009 is a structural and functional homolog to the key morphogenesis component RodZ and interacts with division septal plane localized MreB. Molecular Microbiology. 95: 365-82. PMID 25382739 DOI: 10.1111/Mmi.12855  0.693
2014 Barta ML, Thomas K, Yuan H, Lovell S, Battaile KP, Schramm VL, Hefty PS. Structural and biochemical characterization of Chlamydia trachomatis hypothetical protein CT263 supports that menaquinone synthesis occurs through the futalosine pathway. The Journal of Biological Chemistry. 289: 32214-29. PMID 25253688 DOI: 10.1074/Jbc.M114.594325  0.692
2014 Osaka I, Hefty PS. Lipopolysaccharide-binding alkylpolyamine DS-96 inhibits Chlamydia trachomatis infection by blocking attachment and entry. Antimicrobial Agents and Chemotherapy. 58: 3245-54. PMID 24663021 DOI: 10.1128/Aac.02391-14  0.684
2014 Barta ML, Hickey JM, Anbanandam A, Dyer K, Hammel M, Hefty PS. Atypical response regulator ChxR from Chlamydia trachomatis is structurally poised for DNA binding. Plos One. 9: e91760. PMID 24646934 DOI: 10.1371/Journal.Pone.0091760  0.678
2014 Barta ML, Lovell S, Sinclair AN, Battaile KP, Hefty PS. Chlamydia trachomatis CT771 (nudH) is an asymmetric Ap4A hydrolase. Biochemistry. 53: 214-24. PMID 24354275 DOI: 10.1021/Bi401473E  0.682
2013 Barta ML, Hickey J, Kemege KE, Lovell S, Battaile KP, Hefty PS. Structure of CT584 from Chlamydia trachomatis refined to 3.05 Å resolution. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 69: 1196-201. PMID 24192348 DOI: 10.1107/S1744309113027371  0.698
2013 Wickstrum J, Sammons LR, Restivo KN, Hefty PS. Conditional gene expression in Chlamydia trachomatis using the tet system. Plos One. 8: e76743. PMID 24116144 DOI: 10.1371/Journal.Pone.0076743  0.687
2013 Koppolu V, Osaka I, Skredenske JM, Kettle B, Hefty PS, Li J, Egan SM. Small-molecule inhibitor of the Shigella flexneri master virulence regulator VirF. Infection and Immunity. 81: 4220-31. PMID 24002059 DOI: 10.1128/Iai.00919-13  0.692
2013 Osaka I, Hefty PS. Simple resazurin-based microplate assay for measuring Chlamydia infections. Antimicrobial Agents and Chemotherapy. 57: 2838-40. PMID 23507273 DOI: 10.1128/Aac.00056-13  0.658
2012 Osaka I, Hills JM, Kieweg SL, Shinogle HE, Moore DS, Hefty PS. An automated image-based method for rapid analysis of Chlamydia infection as a tool for screening antichlamydial agents. Antimicrobial Agents and Chemotherapy. 56: 4184-8. PMID 22615279 DOI: 10.1128/Aac.00427-12  0.649
2011 Kemege KE, Hickey JM, Lovell S, Battaile KP, Zhang Y, Hefty PS. Ab initio structural modeling of and experimental validation for Chlamydia trachomatis protein CT296 reveal structural similarity to Fe(II) 2-oxoglutarate-dependent enzymes. Journal of Bacteriology. 193: 6517-28. PMID 21965559 DOI: 10.1128/Jb.05488-11  0.683
2011 Hickey JM, Lovell S, Battaile KP, Hu L, Middaugh CR, Hefty PS. The atypical response regulator protein ChxR has structural characteristics and dimer interface interactions that are unique within the OmpR/PhoB subfamily. The Journal of Biological Chemistry. 286: 32606-16. PMID 21775428 DOI: 10.1074/jbc.M111.220574  0.673
2011 Hickey JM, Weldon L, Hefty PS. The atypical OmpR/PhoB response regulator ChxR from Chlamydia trachomatis forms homodimers in vivo and binds a direct repeat of nucleotide sequences. Journal of Bacteriology. 193: 389-98. PMID 21057008 DOI: 10.1128/JB.00833-10  0.687
2009 Markham AP, Jaafar ZA, Kemege KE, Middaugh CR, Hefty PS. Biophysical characterization of Chlamydia trachomatis CT584 supports its potential role as a type III secretion needle tip protein. Biochemistry. 48: 10353-61. PMID 19769366 DOI: 10.1021/Bi901200Y  0.686
2009 Hickey JM, Hefty PS, Lamb AL. Expression, purification, crystallization and preliminary X-ray analysis of the DNA-binding domain of a Chlamydia trachomatis OmpR/PhoB-subfamily response regulator homolog, ChxR Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 65: 791-794. PMID 19652341 DOI: 10.1107/S1744309109025184  0.685
2009 Abromaitis S, Hefty PS, Stephens RS. Chlamydia pneumoniae encodes a functional aromatic amino acid hydroxylase. Fems Immunology and Medical Microbiology. 55: 196-205. PMID 19141112 DOI: 10.1111/J.1574-695X.2008.00511.X  0.7
2008 Alitalo A, Meri T, Lankinen H, Cheng Z, Jokiranta S, Seppälä I, Lahdenne P, Brooks C, Hefty PS, Akins DR, Meri S. Lysine-Dependent Binding of OspE to the C-terminus of Factor H Mediates Complement Resistance in Borrelia burgdorferi Scandinavian Journal of Immunology. 59: 624-625. DOI: 10.1111/J.0300-9475.2004.01423Aj.X  0.744
2007 Hefty PS, Stephens RS. Chlamydial type III secretion system is encoded on ten operons preceded by sigma 70-like promoter elements. Journal of Bacteriology. 189: 198-206. PMID 17056752 DOI: 10.1128/Jb.01034-06  0.691
2006 Koo IC, Walthers D, Hefty PS, Kenney LJ, Stephens RS. ChxR is a transcriptional activator in Chlamydia. Proceedings of the National Academy of Sciences of the United States of America. 103: 750-5. PMID 16407127 DOI: 10.1073/Pnas.0509690103  0.71
2006 Hua L, Hefty PS, Lee YJ, Lee YM, Stephens RS, Price CW. Core of the partner switching signalling mechanism is conserved in the obligate intracellular pathogen Chlamydia trachomatis. Molecular Microbiology. 59: 623-36. PMID 16390455 DOI: 10.1111/J.1365-2958.2005.04962.X  0.69
2004 Alitalo A, Meri T, Chen T, Lankinen H, Cheng ZZ, Jokiranta TS, Seppälä IJ, Lahdenne P, Hefty PS, Akins DR, Meri S. Lysine-dependent multipoint binding of the Borrelia burgdorferi virulence factor outer surface protein E to the C terminus of factor H. Journal of Immunology (Baltimore, Md. : 1950). 172: 6195-201. PMID 15128807  0.75
2003 Brooks CS, Hefty PS, Jolliff SE, Akins DR. Global analysis of Borrelia burgdorferi genes regulated by mammalian host-specific signals. Infection and Immunity. 71: 3371-83. PMID 12761121 DOI: 10.1128/Iai.71.6.3371-3383.2003  0.762
2002 Hefty PS, Brooks CS, Jett AM, White GL, Wikel SK, Kennedy RC, Akins DR. OspE-related, OspF-related, and Elp lipoproteins are immunogenic in baboons experimentally infected with Borrelia burgdorferi and in human lyme disease patients. Journal of Clinical Microbiology. 40: 4256-65. PMID 12409407 DOI: 10.1128/Jcm.40.11.4256-4265.2002  0.739
2002 Alitalo A, Meri T, Lankinen H, Seppälä I, Lahdenne P, Hefty PS, Akins D, Meri S. Complement inhibitor factor H binding to Lyme disease spirochetes is mediated by inducible expression of multiple plasmid-encoded outer surface protein E paralogs. Journal of Immunology (Baltimore, Md. : 1950). 169: 3847-53. PMID 12244181 DOI: 10.4049/Jimmunol.169.7.3847  0.763
2002 Hefty PS, Jolliff SE, Caimano MJ, Wikel SK, Akins DR. Changes in temporal and spatial patterns of outer surface lipoprotein expression generate population heterogeneity and antigenic diversity in the Lyme disease spirochete, Borrelia burgdorferi. Infection and Immunity. 70: 3468-78. PMID 12065486 DOI: 10.1128/IAI.70.7.3468-3478.2002  0.754
2001 Hefty PS, Jolliff SE, Caimano MJ, Wikel SK, Radolf JD, Akins DR. Regulation of OspE-related, OspF-related, and Elp lipoproteins of Borrelia burgdorferi strain 297 by mammalian host-specific signals. Infection and Immunity. 69: 3618-27. PMID 11349022 DOI: 10.1128/IAI.69.6.3618-3627.2001  0.794
1999 Watts AM, Stanley JR, Shearer MH, Hefty PS, Kennedy RC. Fetal immunization of baboons induces a fetal-specific antibody response. Nature Medicine. 5: 427-30. PMID 10202933 DOI: 10.1038/7426  0.643
1999 Hefty PS, Kennedy RC. Immunoglobulin variable regions as idiotype vaccines. Infectious Disease Clinics of North America. 13: 27-37, vi. PMID 10198790 DOI: 10.1016/S0891-5520(05)70041-6  0.637
Low-probability matches (unlikely to be authored by this person)
1998 Hefty PS, Benton P, Kennedy RC. Humoral immune response to an immunodominant HCV core epitope in HCV/HGV coinfected patients Faseb Journal. 12: A1069.  0.071
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