| Year |
Citation |
Score |
| 2018 |
Karagiannis GS, Sharma VP, Brizio S, Burt J, Wang Y, Entenberg D, Smith B, Flynn D, Oktay MH, Condeelis J. Abstract B030: Neoadjuvant chemotherapy promotes macrophage-induced MenaINV-dependent pro-metastatic changes in breast tumors Molecular Cancer Therapeutics. 17. DOI: 10.1158/1535-7163.Targ-17-B030 |
0.322 |
|
| 2017 |
Groot Jd, George S, Razak A, Gordon M, Janku F, Ligon K, Wen P, Friedlander S, Flynn D, Kaufman M, Pitman J, Ruiz-Soto R, Smith B, Westwood D, Rosen O, et al. ACTR-02. DCC-2618, A NOVEL pan-KIT AND PDGFRa KINASE SWITCH CONTROL INHIBITOR, SHOWS ENCOURAGING SIGNAL IN A PATIENT (PT) WITH GLIOBLASTOMA (GBM) Neuro-Oncology. 19. DOI: 10.1093/Neuonc/Nox168.002 |
0.312 |
|
| 2015 |
Cunnick JM, Kim S, Hadsell J, Collins S, Cerra C, Reiser P, Flynn DC, Cho Y. Actin filament-associated protein 1 is required for cSrc activity and secretory activation in the lactating mammary gland. Oncogene. 34: 2640-9. PMID 25043309 DOI: 10.1038/Onc.2014.205 |
0.395 |
|
| 2015 |
Leung E, Wang Y, Smith B, Flynn D, Condeelis J. Abstract 5091: Inhibiting endothelium directed tumor cell streaming by targeting the HGF/C-Met and EGF/CSF-1 signaling pathways Cancer Research. 75: 5091-5091. DOI: 10.1158/1538-7445.Am2015-5091 |
0.325 |
|
| 2015 |
Pignatelli J, Jones J, Chen X, Smith B, Flynn D, Condeelis J, Oktay M. Abstract 4112: Mechanisms of transendothelial migration by invasive breast carcinoma cells from patients Cancer Research. 75: 4112-4112. DOI: 10.1158/1538-7445.Am2015-4112 |
0.309 |
|
| 2014 |
Sims-Mourtada J, Opdenaker LM, Davis J, Arnold KM, Flynn D. Taxane-induced hedgehog signaling is linked to expansion of breast cancer stem-like populations after chemotherapy. Molecular Carcinogenesis. PMID 25263583 DOI: 10.1002/Mc.22225 |
0.302 |
|
| 2011 |
Snyder BN, Cho Y, Qian Y, Coad JE, Flynn DC, Cunnick JM. AFAP1L1 is a novel adaptor protein of the AFAP family that interacts with cortactin and localizes to invadosomes. European Journal of Cell Biology. 90: 376-89. PMID 21333378 DOI: 10.1016/J.Ejcb.2010.11.016 |
0.764 |
|
| 2010 |
Clump DA, Yu JJ, Cho Y, Gao R, Jett J, Zot H, Cunnick JM, Snyder B, Clump AC, Dodrill M, Gannett P, Coad JE, Shurina R, Figg WD, Reed E, ... Flynn DC, et al. A Polymorphic Variant of AFAP-110 Enhances cSrc Activity. Translational Oncology. 3: 276-85. PMID 20689769 DOI: 10.1593/Tlo.10106 |
0.71 |
|
| 2009 |
Xu X, Harder J, Flynn DC, Lanier LM. AFAP120 regulates actin organization during neuronal differentiation. Differentiation; Research in Biological Diversity. 77: 38-47. PMID 19281763 DOI: 10.1016/j.diff.2008.09.006 |
0.399 |
|
| 2008 |
Dorfleutner A, Cho Y, Vincent D, Cunnick J, Lin H, Weed SA, Stehlik C, Flynn DC. Phosphorylation of AFAP-110 affects podosome lifespan in A7r5 cells. Journal of Cell Science. 121: 2394-405. PMID 18577577 DOI: 10.1242/Jcs.026187 |
0.383 |
|
| 2007 |
Zhang J, Park SI, Artime MC, Summy JM, Shah AN, Bomser JA, Dorfleutner A, Flynn DC, Gallick GE. AFAP-110 is overexpressed in prostate cancer and contributes to tumorigenic growth by regulating focal contacts. The Journal of Clinical Investigation. 117: 2962-73. PMID 17885682 DOI: 10.1172/Jci30710 |
0.711 |
|
| 2007 |
Walker VG, Ammer A, Cao Z, Clump AC, Jiang BH, Kelley LC, Weed SA, Zot H, Flynn DC. PI3K activation is required for PMA-directed activation of cSrc by AFAP-110. American Journal of Physiology. Cell Physiology. 293: C119-32. PMID 17360811 DOI: 10.1152/Ajpcell.00525.2006 |
0.749 |
|
| 2007 |
Dorfleutner A, Bryan NB, Talbott SJ, Funya KN, Rellick SL, Reed JC, Shi X, Rojanasakul Y, Flynn DC, Stehlik C. Cellular pyrin domain-only protein 2 is a candidate regulator of inflammasome activation. Infection and Immunity. 75: 1484-92. PMID 17178784 DOI: 10.1128/Iai.01315-06 |
0.345 |
|
| 2005 |
Clump DA, Qazi IH, Sudol M, Flynn DC. c-Yes response to growth factor activation. Growth Factors (Chur, Switzerland). 23: 263-72. PMID 16338789 DOI: 10.1080/08977190500199360 |
0.663 |
|
| 2005 |
Qian Y, Zhong X, Flynn DC, Zheng JZ, Qiao M, Wu C, Dedhar S, Shi X, Jiang BH. ILK mediates actin filament rearrangements and cell migration and invasion through PI3K/Akt/Rac1 signaling. Oncogene. 24: 3154-65. PMID 15735674 DOI: 10.1038/Sj.Onc.1208525 |
0.416 |
|
| 2005 |
Qian Y, Liu KJ, Chen Y, Flynn DC, Castranova V, Shi X. Cdc42 regulates arsenic-induced NADPH oxidase activation and cell migration through actin filament reorganization. The Journal of Biological Chemistry. 280: 3875-84. PMID 15492012 DOI: 10.1074/jbc.M403788200 |
0.335 |
|
| 2004 |
Gatesman A, Walker VG, Baisden JM, Weed SA, Flynn DC. Protein kinase Calpha activates c-Src and induces podosome formation via AFAP-110. Molecular and Cellular Biology. 24: 7578-97. PMID 15314167 DOI: 10.1128/Mcb.24.17.7578-7597.2004 |
0.798 |
|
| 2004 |
Gao N, Flynn DC, Zhang Z, Zhong XS, Walker V, Liu KJ, Shi X, Jiang BH. G1 cell cycle progression and the expression of G1 cyclins are regulated by PI3K/AKT/mTOR/p70S6K1 signaling in human ovarian cancer cells. American Journal of Physiology. Cell Physiology. 287: C281-91. PMID 15028555 DOI: 10.1152/Ajpcell.00422.2003 |
0.707 |
|
| 2004 |
Qian Y, Gatesman AS, Baisden JM, Zot HG, Cherezova L, Qazi I, Mazloum N, Lee MY, Guappone-Koay A, Flynn DC. Analysis of the role of the leucine zipper motif in regulating the ability of AFAP-110 to alter actin filament integrity. Journal of Cellular Biochemistry. 91: 602-20. PMID 14755689 DOI: 10.1002/Jcb.10725 |
0.779 |
|
| 2004 |
Qian Y, Corum L, Meng Q, Blenis J, Zheng JZ, Shi X, Flynn DC, Jiang BH. PI3K induced actin filament remodeling through Akt and p70S6K1: implication of essential role in cell migration. American Journal of Physiology. Cell Physiology. 286: C153-63. PMID 12967912 DOI: 10.1152/Ajpcell.00142.2003 |
0.393 |
|
| 2003 |
Summy JM, Qian Y, Jiang BH, Guappone-Koay A, Gatesman A, Shi X, Flynn DC. The SH4-Unique-SH3-SH2 domains dictate specificity in signaling that differentiate c-Yes from c-Src. Journal of Cell Science. 116: 2585-98. PMID 12734402 DOI: 10.1242/Jcs.00466 |
0.751 |
|
| 2003 |
Clump DA, Clem R, Qian Y, Guappone-Koay A, Berrebi AS, Flynn DC. Protein expression levels of the Src activating protein AFAP are developmentally regulated in brain. Journal of Neurobiology. 54: 473-85. PMID 12532398 DOI: 10.1002/Neu.10143 |
0.651 |
|
| 2003 |
Summy JM, Sudol M, Eck MJ, Monteiro AN, Gatesman A, Flynn DC. Specificity in signaling by c-Yes. Frontiers in Bioscience : a Journal and Virtual Library. 8: s185-205. PMID 12456296 DOI: 10.2741/1011 |
0.719 |
|
| 2002 |
Berwanger B, Hartmann O, Bergmann E, Bernard S, Nielsen D, Krause M, Kartal A, Flynn D, Wiedemeyer R, Schwab M, Schäfer H, Christiansen H, Eilers M. Loss of a FYN-regulated differentiation and growth arrest pathway in advanced stage neuroblastoma. Cancer Cell. 2: 377-86. PMID 12450793 DOI: 10.1016/S1535-6108(02)00179-4 |
0.378 |
|
| 2002 |
Qian Y, Baisden JM, Cherezova L, Summy JM, Guappone-Koay A, Shi X, Mast T, Pustula J, Zot HG, Mazloum N, Lee MY, Flynn DC. PC phosphorylation increases the ability of AFAP-110 to cross-link actin filaments. Molecular Biology of the Cell. 13: 2311-22. PMID 12134071 DOI: 10.1091/Mbc.E01-12-0148 |
0.801 |
|
| 2002 |
Cherezova L, Gatesman A, Flynn DC. The effects of phosphorylation on adaptor protein function. Frontiers in Bioscience : a Journal and Virtual Library. 7: d164-203. PMID 11779691 |
0.318 |
|
| 2001 |
Baisden JM, Gatesman AS, Cherezova L, Jiang BH, Flynn DC. The intrinsic ability of AFAP-110 to alter actin filament integrity is linked with its ability to also activate cellular tyrosine kinases. Oncogene. 20: 6607-16. PMID 11641786 DOI: 10.1038/Sj.Onc.1204802 |
0.806 |
|
| 2001 |
Baisden JM, Qian Y, Zot HM, Flynn DC. The actin filament-associated protein AFAP-110 is an adaptor protein that modulates changes in actin filament integrity. Oncogene. 20: 6435-47. PMID 11607843 DOI: 10.1038/Sj.Onc.1204784 |
0.804 |
|
| 2001 |
Hoey JG, Summy J, Flynn DC. Chimeric constructs containing the SH4/Unique domains of cYes can restrict the ability of Src(527F) to upregulate heme oxygenase-1 expression efficiently. Cellular Signalling. 12: 691-701. PMID 11080622 DOI: 10.1016/S0898-6568(00)00116-9 |
0.742 |
|
| 2001 |
Hoey JG, Summy J, Flynn DC. Erratum to “Chimeric construct containing the SH4/Unique domains of cYes can restrict the ability of Src527F to upregulate heme oxygenese-1 expression efficiently” [Cell. Signal. 12 (2000) 691–701] Cellular Signalling. 13: 71. DOI: 10.1016/S0898-6568(01)00128-0 |
0.723 |
|
| 2000 |
Qian Y, Baisden JM, Zot HG, Van Winkle WB, Flynn DC. The carboxy terminus of AFAP-110 modulates direct interactions with actin filaments and regulates its ability to alter actin filament integrity and induce lamellipodia formation. Experimental Cell Research. 255: 102-13. PMID 10666339 DOI: 10.1006/Excr.1999.4795 |
0.789 |
|
| 2000 |
Summy JM, Guappone AC, Sudol M, Flynn DC. The SH3 and SH2 domains are capable of directing specificity in protein interactions between the non-receptor tyrosine kinases cSrc and cYes. Oncogene. 19: 155-60. PMID 10644991 DOI: 10.1038/Sj.Onc.1203265 |
0.755 |
|
| 1999 |
Qian Y, Guappone AC, Baisden JM, Hill MW, Summy JM, Flynn DC. Monoclonal antibodies directed against AFAP-110 recognize species- specific and conserved epitopes Hybridoma. 18: 167-175. PMID 10380016 |
0.782 |
|
| 1998 |
Guappone AC, Weimer T, Flynn DC. Formation of a stable src-AFAP-110 complex through either an amino-terminal or a carboxy-terminal SH2-binding motif. Molecular Carcinogenesis. 22: 110-9. PMID 9655255 DOI: 10.1002/(SICI)1098-2744(199806)22:2<110::AID-MC6>3.0.CO;2-Q |
0.389 |
|
| 1998 |
Qian Y, Baisden JM, Westin EH, Guappone AC, Koay TC, Flynn DC. Src can regulate carboxy terminal interactions with AFAP-110, which influence self-association, cell localization and actin filament integrity. Oncogene. 16: 2185-95. PMID 9619827 DOI: 10.1038/Sj.Onc.1201753 |
0.779 |
|
| 1997 |
Guappone AC, Flynn DC. The integrity of the SH3 binding motif of AFAP-110 is required to facilitate tyrosine phosphorylation by, and stable complex formation with, Src. Molecular and Cellular Biochemistry. 175: 243-52. PMID 9350057 DOI: 10.1023/A:1006840104666 |
0.388 |
|
| 1993 |
Schaller MD, Bouton AH, Flynn DC, Parsons JT. Identification and characterization of novel substrates for protein tyrosine kinases Progress in Nucleic Acid Research and Molecular Biology. 44: 205-227. PMID 8434124 DOI: 10.1016/S0079-6603(08)60221-4 |
0.333 |
|
| 1993 |
Flynn DC, Leu TH, Reynolds AB, Parsons JT. Identification and sequence analysis of cDNAs encoding a 110-kilodalton actin filament-associated pp60src substrate. Molecular and Cellular Biology. 13: 7892-900. PMID 8247004 DOI: 10.1128/mcb.13.12.7892-7900.1993 |
0.422 |
|
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