Lucio Comai - Publications

Affiliations: 
Genetic, Molecular, and Cell Biology University of Southern California, Los Angeles, CA, United States 
Area:
Molecular Biology, Cell Biology, Genetics

69 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Li B, Reddy S, Comai L. The Werner syndrome helicase coordinates sequential strand displacement and FEN1-mediated flap cleavage during Polymerase δ elongation. Molecular and Cellular Biology. PMID 27849570 DOI: 10.1128/Mcb.00560-16  0.37
2016 Reddy S, Comai L. Recent advances in understanding the role of lamins in health and disease. F1000research. 5: 2536. PMID 27803806 DOI: 10.12688/F1000Research.9260.1  0.338
2016 Choi J, Dixon DM, Dansithong W, Abdallah WF, Roos KP, Jordan MC, Trac B, Lee HS, Comai L, Reddy S. Muscleblind-like 3 deficit results in a spectrum of age-associated pathologies observed in myotonic dystrophy. Scientific Reports. 6: 30999. PMID 27484195 DOI: 10.1038/Srep30999  0.341
2015 Cárdenas-Conejo Y, Carballo-Uicab V, Lieberman M, Aguilar-Espinosa M, Comai L, Rivera-Madrid R. De novo transcriptome sequencing in Bixa orellana to identify genes involved in methylerythritol phosphate, carotenoid and bixin biosynthesis. Bmc Genomics. 16: 877. PMID 26511010 DOI: 10.1186/S12864-015-2065-4  0.334
2015 Choi J, Personius KE, DiFranco M, Dansithong W, Yu C, Srivastava S, Dixon DM, Bhatt DB, Comai L, Vergara JL, Reddy S. Muscleblind-Like 1 and Muscleblind-Like 3 Depletion Synergistically Enhances Myotonia by Altering Clc-1 RNA Translation. Ebiomedicine. 2: 1034-47. PMID 26501102 DOI: 10.1016/J.Ebiom.2015.07.028  0.364
2015 Burkart-Waco D, Ngo K, Lieberman M, Comai L. Perturbation of parentally biased gene expression during interspecific hybridization. Plos One. 10: e0117293. PMID 25719202 DOI: 10.1371/Journal.Pone.0117293  0.304
2014 Li B, Iglesias-Pedraz JM, Chen LY, Yin F, Cadenas E, Reddy S, Comai L. Downregulation of the Werner syndrome protein induces a metabolic shift that compromises redox homeostasis and limits proliferation of cancer cells. Aging Cell. 13: 367-78. PMID 24757718 DOI: 10.1111/Acel.12181  0.367
2012 Jog SP, Paul S, Dansithong W, Tring S, Comai L, Reddy S. RNA splicing is responsive to MBNL1 dose. Plos One. 7: e48825. PMID 23166594 DOI: 10.1371/Journal.Pone.0048825  0.356
2012 Candelario J, Chen LY, Marjoram P, Reddy S, Comai L. A filtering strategy identifies FOXQ1 as a potential effector of lamin A dysfunction. Aging. 4: 567-77. PMID 22948034  0.746
2012 Reddy S, Comai L. Lamin A, farnesylation and aging. Experimental Cell Research. 318: 1-7. PMID 21871450 DOI: 10.1016/J.Yexcr.2011.08.009  0.379
2012 Missirian V, Henry I, Comai L, Filkov V. POPE: Pipeline of parentally-biased expression Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 7292: 177-188. DOI: 10.1007/978-3-642-30191-9_17  0.319
2011 Paul S, Dansithong W, Jog SP, Holt I, Mittal S, Brook JD, Morris GE, Comai L, Reddy S. Expanded CUG repeats Dysregulate RNA splicing by altering the stoichiometry of the muscleblind 1 complex. The Journal of Biological Chemistry. 286: 38427-38. PMID 21900255 DOI: 10.1074/Jbc.M111.255224  0.366
2011 Dansithong W, Jog SP, Paul S, Mohammadzadeh R, Tring S, Kwok Y, Fry RC, Marjoram P, Comai L, Reddy S. RNA steady-state defects in myotonic dystrophy are linked to nuclear exclusion of SHARP. Embo Reports. 12: 735-42. PMID 21637295 DOI: 10.1038/Embor.2011.86  0.463
2011 Jog SP, Reddy S, Comai L. Cell cycle-regulated association between the Werner syndrome protein and its molecular partners. Cell Cycle (Georgetown, Tex.). 10: 2038-40. PMID 21558813 DOI: 10.4161/Cc.10.12.16044  0.355
2011 Candelario J, Borrego S, Reddy S, Comai L. Accumulation of distinct prelamin A variants in human diploid fibroblasts differentially affects cell homeostasis. Experimental Cell Research. 317: 319-29. PMID 20974128 DOI: 10.1016/J.Yexcr.2010.10.014  0.763
2010 Reddy S, Li B, Comai L. Processing of human telomeres by the Werner syndrome protein. Cell Cycle (Georgetown, Tex.). 9: 3137-8. PMID 20814240 DOI: 10.4161/Cc.9.16.12952  0.384
2010 Pignatta D, Dilkes BP, Yoo SY, Henry IM, Madlung A, Doerge RW, Jeffrey Chen Z, Comai L. Differential sensitivity of the Arabidopsis thaliana transcriptome and enhancers to the effects of genome doubling. The New Phytologist. 186: 194-206. PMID 20409178 DOI: 10.1111/J.1469-8137.2010.03198.X  0.326
2009 Li B, Jog S, Candelario J, Reddy S, Comai L. Altered nuclear functions in progeroid syndromes: a paradigm for aging research. Thescientificworldjournal. 9: 1449-62. PMID 20024518 DOI: 10.1100/Tsw.2009.159  0.683
2009 Liu Y, Stanford SM, Jog SP, Fiorillo E, Orrú V, Comai L, Bottini N. Regulation of lymphoid tyrosine phosphatase activity: inhibition of the catalytic domain by the proximal interdomain. Biochemistry. 48: 7525-32. PMID 19586056 DOI: 10.1021/Bi900332F  0.339
2009 Walia H, Josefsson C, Dilkes B, Kirkbride R, Harada J, Comai L. Dosage-Dependent Deregulation of an AGAMOUS-LIKE Gene Cluster Contributes to Interspecific Incompatibility Current Biology. 19: 1128-1132. PMID 19559614 DOI: 10.1016/J.Cub.2009.05.068  0.751
2008 Dansithong W, Wolf CM, Sarkar P, Paul S, Chiang A, Holt I, Morris GE, Branco D, Sherwood MC, Comai L, Berul CI, Reddy S. Cytoplasmic CUG RNA foci are insufficient to elicit key DM1 features. Plos One. 3: e3968. PMID 19092997 DOI: 10.1371/Journal.Pone.0003968  0.403
2008 Pignatta D, Dilkes B, Wroblewski T, Michelmore RW, Comai L. Transgene-induced gene silencing is not affected by a change in ploidy level Plos One. 3. PMID 18725969 DOI: 10.1371/Journal.Pone.0003061  0.34
2008 Candelario J, Sudhakar S, Navarro S, Reddy S, Comai L. Perturbation of wild-type lamin A metabolism results in a progeroid phenotype. Aging Cell. 7: 355-67. PMID 18363904 DOI: 10.1111/J.1474-9726.2008.00393.X  0.733
2008 Li B, Jog SP, Reddy S, Comai L. WRN controls formation of extrachromosomal telomeric circles and is required for TRF2DeltaB-mediated telomere shortening. Molecular and Cellular Biology. 28: 1892-904. PMID 18212065 DOI: 10.1128/Mcb.01364-07  0.393
2008 Madia F, Gattazzo C, Wei M, Fabrizio P, Burhans WC, Weinberger M, Galbani A, Smith JR, Nguyen C, Huey S, Comai L, Longo VD. Longevity mutation in SCH9 prevents recombination errors and premature genomic instability in a Werner/Bloom model system. The Journal of Cell Biology. 180: 67-81. PMID 18195102 DOI: 10.1083/Jcb.200707154  0.322
2007 Lin CH, Platt MD, Ficarro SB, Hoofnagle MH, Shabanowitz J, Comai L, Hunt DF, Owens GK. Mass spectrometric identification of phosphorylation sites of rRNA transcription factor upstream binding factor. American Journal of Physiology. Cell Physiology. 292: C1617-24. PMID 17182730 DOI: 10.1152/Ajpcell.00176.2006  0.403
2006 Lin CY, Navarro S, Reddy S, Comai L. CK2-mediated stimulation of Pol I transcription by stabilization of UBF-SL1 interaction. Nucleic Acids Research. 34: 4752-66. PMID 16971462 DOI: 10.1093/Nar/Gkl581  0.774
2006 Paul S, Dansithong W, Kim D, Rossi J, Webster NJ, Comai L, Reddy S. Interaction of muscleblind, CUG-BP1 and hnRNP H proteins in DM1-associated aberrant IR splicing. The Embo Journal. 25: 4271-83. PMID 16946708 DOI: 10.1038/Sj.Emboj.7601296  0.341
2006 Ditt RF, Kerr KF, de Figueiredo P, Delrow J, Comai L, Nester EW. The Arabidopsis thaliana transcriptome in response to Agrobacterium tumefaciens. Molecular Plant-Microbe Interactions : Mpmi. 19: 665-81. PMID 16776300 DOI: 10.1094/Mpmi-19-0665  0.346
2006 Wang J, Tian L, Lee HS, Wei NE, Jiang H, Watson B, Madlung A, Osborn TC, Doerge RW, Comai L, Chen ZJ. Genomewide nonadditive gene regulation in Arabidopsis allotetraploids. Genetics. 172: 507-17. PMID 16172500 DOI: 10.1534/Genetics.105.047894  0.365
2005 Li B, Conway N, Navarro S, Comai L, Comai L. A conserved and species-specific functional interaction between the Werner syndrome-like exonuclease atWEX and the Ku heterodimer in Arabidopsis. Nucleic Acids Research. 33: 6861-7. PMID 16396834 DOI: 10.1093/Nar/Gki984  0.337
2005 Sheng Z, Liang Y, Lin CY, Comai L, Chirico WJ. Direct regulation of rRNA transcription by fibroblast growth factor 2. Molecular and Cellular Biology. 25: 9419-26. PMID 16227592 DOI: 10.1128/Mcb.25.21.9419-9426.2005  0.774
2005 Zhang C, Comai L, Johnson DL. PTEN represses RNA Polymerase I transcription by disrupting the SL1 complex. Molecular and Cellular Biology. 25: 6899-911. PMID 16055704 DOI: 10.1128/Mcb.25.16.6899-6911.2005  0.482
2005 Banerjee R, Weidman MK, Navarro S, Comai L, Dasgupta A. Modifications of both selectivity factor and upstream binding factor contribute to poliovirus-mediated inhibition of RNA polymerase I transcription. The Journal of General Virology. 86: 2315-22. PMID 16033979 DOI: 10.1099/Vir.0.80817-0  0.424
2005 Dansithong W, Paul S, Comai L, Reddy S. MBNL1 is the primary determinant of focus formation and aberrant insulin receptor splicing in DM1. The Journal of Biological Chemistry. 280: 5773-80. PMID 15546872 DOI: 10.1074/Jbc.M410781200  0.387
2004 Lee HS, Wang J, Tian L, Jiang H, Black MA, Madlung A, Watson B, Lukens L, Pires JC, Wang JJ, Comai L, Osborn TC, Doerge RW, Chen ZJ. Sensitivity of 70-mer oligonucleotides and cDNAs for microarray analysis of gene expression in Arabidopsis and its related species. Plant Biotechnology Journal. 2: 45-57. PMID 17166142 DOI: 10.1046/J.1467-7652.2003.00048.X  0.337
2004 Wang J, Tian L, Madlung A, Lee HS, Chen M, Lee JJ, Watson B, Kagochi T, Comai L, Chen ZJ. Stochastic and epigenetic changes of gene expression in Arabidopsis polyploids. Genetics. 167: 1961-73. PMID 15342533 DOI: 10.1534/Genetics.104.027896  0.366
2004 Comai L, Li B. The Werner syndrome protein at the crossroads of DNA repair and apoptosis. Mechanisms of Ageing and Development. 125: 521-8. PMID 15336909 DOI: 10.1016/J.Mad.2004.06.004  0.393
2004 Comai L. Mechanism of RNA polymerase I transcription. Advances in Protein Chemistry. 67: 123-55. PMID 14969726 DOI: 10.1016/S0065-3233(04)67005-7  0.444
2004 Li B, Navarro S, Kasahara N, Comai L. Identification and biochemical characterization of a Werner's syndrome protein complex with Ku70/80 and poly(ADP-ribose) polymerase-1. The Journal of Biological Chemistry. 279: 13659-67. PMID 14734561 DOI: 10.1074/Jbc.M311606200  0.417
2003 Osborn TC, Pires JC, Birchler JA, Auger DL, Chen ZJ, Lee HS, Comai L, Madlung A, Doerge RW, Colot V, Martienssen RA. Understanding mechanisms of novel gene expression in polyploids. Trends in Genetics : Tig. 19: 141-7. PMID 12615008 DOI: 10.1016/S0168-9525(03)00015-5  0.302
2002 Lin CY, Tuan J, Scalia P, Bui T, Comai L. The cell cycle regulatory factor TAF1 stimulates ribosomal DNA transcription by binding to the activator UBF. Current Biology : Cb. 12: 2142-6. PMID 12498690 DOI: 10.1016/S0960-9822(02)01389-1  0.782
2001 Holmes-Davis R, Comai L. The matrix attachment regions (MARS) associated with the Heat Shock Cognate 80 gene (HSC80) of tomato represent specific regulatory elements Molecular Genetics and Genomics. 266: 891-898. PMID 11810265 DOI: 10.1007/S00438-001-0613-X  0.367
2001 Ditt RF, Nester EW, Comai L. Plant gene expression response to Agrobacterium tumefaciens Proceedings of the National Academy of Sciences of the United States of America. 98: 10954-10959. PMID 11535836 DOI: 10.1073/Pnas.191383498  0.314
2001 Li B, Comai L. Requirements for the Nucleolytic Processing of DNA Ends by the Werner Syndrome Protein-Ku70/80 Complex Journal of Biological Chemistry. 276: 9896-9902. PMID 11152456 DOI: 10.1074/Jbc.M008575200  0.373
2001 Holmes-Davis R, Payne SR, Comai L. The effects of kinetin and hydroxyurea on the expression of the endogenous and transgenic Heat Shock Cognate 80 (HSC80) Plant Cell Reports. 20: 744-748. DOI: 10.1007/S002990100391  0.322
2000 Zhai W, Comai L. Repression of RNA polymerase I transcription by the tumor suppressor p53 Molecular and Cellular Biology. 20: 5930-5938. PMID 10913176 DOI: 10.1128/Mcb.20.16.5930-5938.2000  0.442
2000 Li B, Comai L. Functional interaction between Ku and the Werner syndrome protein in DNA end processing Journal of Biological Chemistry. 275: 28349-28352. PMID 10880505 DOI: 10.1074/Jbc.C000289200  0.35
2000 Comai L, Song Y, Tan C, Bui T. Inhibition of RNA polymerase I transcription in differentiated myeloid leukemia cells by inactivation of selectivity factor 1 Cell Growth and Differentiation. 11: 63-70. PMID 10672904  0.367
1999 Comai L. The nucleolus: A paradigm for cell proliferation and aging Brazilian Journal of Medical and Biological Research. 32: 1473-1478. PMID 10585627 DOI: 10.1590/S0100-879X1999001200004  0.453
1999 Tuan JC, Zhai W, Comai L. Recruitment of TATA-binding protein-TAF(I) complex SL1 to the human ribosomal DNA promoter is mediated by the carboxy-terminal activation domain of upstream binding factor (UBF) and is regulated by UBF phosphorylation Molecular and Cellular Biology. 19: 2872-2879. PMID 10082553 DOI: 10.1128/Mcb.19.4.2872  0.446
1999 Zhai W, Comai L. A kinase activity associated with Simian virus 40 large T antigen phosphorylates upstream binding factor (UBF) and promotes formation of a stable initiation complex between UBF and SL1 Molecular and Cellular Biology. 19: 2791-2802. PMID 10082545 DOI: 10.1128/Mcb.19.4.2791  0.394
1998 Chen J, Comai L, Pikaard CS. Gene dosage and stochastic effects determine the severity and direction of uniparental ribosomal RNA gene silencing (nucleolar dominance) in Arabidopsis allopolyploids Proceedings of the National Academy of Sciences of the United States of America. 95: 14891-14896. PMID 9843986 DOI: 10.1073/Pnas.95.25.14891  0.364
1997 Li HP, Zhang X, Duncan R, Comai L, Lai MMC. Heterogeneous nuclear ribonucleoprotein A1 binds to the transcription- regulatory region of mouse hepatitis virus RNA Proceedings of the National Academy of Sciences of the United States of America. 94: 9544-9549. PMID 9275159 DOI: 10.1073/Pnas.94.18.9544  0.363
1997 Zhai W, Tuan J, Comai L. SV40 large T antigen binds to the TBP-TAF(I) complex SL1 and coactivates ribosomal RNA transcription Genes and Development. 11: 1605-1617. PMID 9203586 DOI: 10.1101/Gad.11.12.1605  0.413
1996 Chinn AM, Comai L. The heat shock cognate 80 gene of tomato is flanked by matrix attachment regions Plant Molecular Biology. 32: 959-968. PMID 8980546 DOI: 10.1007/Bf00020492  0.309
1996 Chinn AM, Payne SR, Comai L. Variegation and silencing of the Heat Shock Cognate 80 gene are relieved by a bipartite downstream regulatory element. The Plant Journal : For Cell and Molecular Biology. 9: 325-39. PMID 8919910 DOI: 10.1046/J.1365-313X.1996.09030325.X  0.314
1996 Roussel P, André C, Comai L, Hernandez-Verdun D. The rDNA transcription machinery is assembled during mitosis in active NORs and absent in inactive NORs Journal of Cell Biology. 133: 235-246. PMID 8609158 DOI: 10.1083/Jcb.133.2.235  0.479
1994 Zhang JZ, Laudencia-Chingcuanco DL, Comai L, Li M, Harada JJ. Isocitrate lyase and malate synthase genes from Brassica napus L. are active in pollen Plant Physiology. 104: 857-864. PMID 8165259 DOI: 10.1104/Pp.104.3.857  0.761
1994 Zomerdijk JCBM, Beckmann H, Comai L, Tjian R. Assembly of transcriptionally active RNA polymerase I initiation factor SL1 from recombinant subunits Science. 266: 2015-2018. PMID 7801130 DOI: 10.1126/Science.7801130  0.428
1994 Comai L, Zomerdijk JCBM, Beckmann H, Zhou S, Admon A, Tjian R. Reconstitution of transcription factor SL1: Exclusive binding of TBP by SL1 or TFIID subunits Science. 266: 1966-1972. PMID 7801123 DOI: 10.1126/Science.7801123  0.399
1992 Koning A, Jones A, Fillatti JJ, Comai L, Lassner MW. Arrest of embryo development in Brassica napus mediated by modified Pseudomonas aeruginosa exotoxin A Plant Molecular Biology. 18: 247-258. PMID 1731987 DOI: 10.1007/Bf00034953  0.31
1992 Comai L, Tanese N, Tjian R. The TATA-binding protein and associated factors are integral components of the RNA polymerase I transcription factor, SL1. Cell. 68: 965-76. PMID 1547496 DOI: 10.1016/0092-8674(92)90039-F  0.443
1991 Koning AJ, Tanimoto EY, Kiehne K, Rost T, Comai L. Cell-specific expression of plant histone H2A genes Plant Cell. 3: 657-665. PMID 1841722 DOI: 10.1105/Tpc.3.7.657  0.323
1991 Lassner MW, Jones A, Daubert S, Comai L. Targeting of T7 RNA polymerase to tobacco nuclei mediated by an SV40 nuclear location signal Plant Molecular Biology. 17: 229-234. PMID 1650616 DOI: 10.1007/Bf00039497  0.302
1990 Comai L, Harada JJ. Transcriptional activities in dry seed nuclei indicate the timing of the transition from embryogeny to germination Proceedings of the National Academy of Sciences of the United States of America. 87: 2671-2674. PMID 2320581 DOI: 10.1073/Pnas.87.7.2671  0.677
1989 Comai L, Baden CS, Harada JJ. Deduced sequence of a malate synthase polypeptide encoded by a subclass of the gene family Journal of Biological Chemistry. 264: 2778-2782. PMID 2914930  0.615
1989 Comai L, Dietrich RA, Maslyar DJ, Baden CS, Harada JJ. Coordinate expression of transcriptionally regulated isocitrate lyase and malate synthase genes in Brassica napus L The Plant Cell. 1: 293-300. PMID 2535504 DOI: 10.1105/Tpc.1.3.293  0.779
1988 Harada JJ, Baden CS, Comai L. Spatially regulated genes expressed during seed germination and postgerminative development are activated during embryogeny Mgg Molecular &Amp; General Genetics. 212: 466-473. DOI: 10.1007/Bf00330851  0.66
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