Year |
Citation |
Score |
2017 |
Royer DJ, Carr MM, Gurung HR, Halford WP, Carr DJJ. The Neonatal Fc Receptor and Complement Fixation Facilitate Prophylactic Vaccine-Mediated Humoral Protection against Viral Infection in the Ocular Mucosa. Journal of Immunology (Baltimore, Md. : 1950). PMID 28760885 DOI: 10.4049/Jimmunol.1700316 |
0.392 |
|
2017 |
Royer DJ, Carr MM, Chucair-Elliott AJ, Halford WP, Carr DJ. Impact of type 1 interferon on the safety and immunogenicity of an experimental live-attenuated herpes simplex virus type 1 vaccine in mice. Journal of Virology. PMID 28122977 DOI: 10.1128/Jvi.02342-16 |
0.461 |
|
2016 |
Royer DJ, Gurung HR, Jinkins JK, Geltz JJ, Wu JL, Halford WP, Carr DJ. A Highly Efficacious HSV-1 Vaccine Blocks Viral Pathogenesis and Prevents Corneal Immunopathology Via Humoral Immunity. Journal of Virology. PMID 27030264 DOI: 10.1128/Jvi.00517-16 |
0.445 |
|
2015 |
Halford WP, Geltz J, Messer RJ, Hasenkrug KJ. Antibodies Are Required for Complete Vaccine-Induced Protection against Herpes Simplex Virus 2. Plos One. 10: e0145228. PMID 26670699 DOI: 10.1371/Journal.Pone.0145228 |
0.45 |
|
2015 |
Ariotti S, Beltman JB, Borsje R, Hoekstra ME, Halford WP, Haanen JB, de Boer RJ, Schumacher TN. Subtle CXCR3-Dependent Chemotaxis of CTLs within Infected Tissue Allows Efficient Target Localization. Journal of Immunology (Baltimore, Md. : 1950). 195: 5285-95. PMID 26525288 DOI: 10.4049/Jimmunol.1500853 |
0.387 |
|
2015 |
Gershburg S, Geltz J, Peterson KE, Halford WP, Gershburg E. The UL13 and US3 Protein Kinases of Herpes Simplex Virus 1 Cooperate to Promote the Assembly and Release of Mature, Infectious Virions. Plos One. 10: e0131420. PMID 26115119 DOI: 10.1371/Journal.Pone.0131420 |
0.479 |
|
2015 |
Chambers CB, Halford WP, Geltz J, Villamizar O, Gross J, Embalabala A, Gershburg E, Wilber A. A system for creating stable cell lines that express a gene of interest from a bidirectional and regulatable herpes simplex virus type 1 promoter. Plos One. 10: e0122253. PMID 25823013 DOI: 10.1371/Journal.Pone.0122253 |
0.374 |
|
2015 |
Geltz JJ, Gershburg E, Halford WP. Herpes simplex virus 2 (HSV-2) infected cell proteins are among the most dominant antigens of a live-attenuated HSV-2 vaccine. Plos One. 10: e0116091. PMID 25658852 DOI: 10.1371/Journal.Pone.0116091 |
0.486 |
|
2014 |
Halford WP. Antigenic breadth: a missing ingredient in HSV-2 subunit vaccines? Expert Review of Vaccines. 13: 691-710. PMID 24837838 DOI: 10.1586/14760584.2014.910121 |
0.417 |
|
2014 |
Workenhe ST, Simmons G, Pol JG, Lichty BD, Halford WP, Mossman KL. Immunogenic HSV-mediated oncolysis shapes the antitumor immune response and contributes to therapeutic efficacy. Molecular Therapy : the Journal of the American Society of Gene Therapy. 22: 123-31. PMID 24343053 DOI: 10.1038/Mt.2013.238 |
0.499 |
|
2013 |
Halford WP, Geltz J, Gershburg E. Pan-HSV-2 IgG antibody in vaccinated mice and guinea pigs correlates with protection against herpes simplex virus 2. Plos One. 8: e65523. PMID 23755244 DOI: 10.1371/Journal.Pone.0065523 |
0.466 |
|
2013 |
Nixon B, Stefanidou M, Mesquita PM, Fakioglu E, Segarra T, Rohan L, Halford W, Palmer KE, Herold BC. Griffithsin protects mice from genital herpes by preventing cell-to-cell spread. Journal of Virology. 87: 6257-69. PMID 23536670 DOI: 10.1128/Jvi.00012-13 |
0.413 |
|
2012 |
Hill JM, Nolan NM, McFerrin HE, Clement C, Foster TP, Halford WP, Kousoulas KG, Lukiw WJ, Thompson HW, Stern EM, Bhattacharjee PS. HSV-1 latent rabbits shed viral DNA into their saliva. Virology Journal. 9: 221. PMID 23021094 DOI: 10.1186/1743-422X-9-221 |
0.403 |
|
2011 |
Wuest T, Zheng M, Efstathiou S, Halford WP, Carr DJJ. The herpes simplex virus-1 transactivator infected cell protein-4 drives VEGF-A dependent Neovascularization Plos Pathogens. 7. PMID 21998580 DOI: 10.1371/Journal.Ppat.1002278 |
0.404 |
|
2011 |
Halford WP, Püschel R, Gershburg E, Wilber A, Gershburg S, Rakowski B. A live-attenuated HSV-2 ICP0 virus elicits 10 to 100 times greater protection against genital herpes than a glycoprotein D subunit vaccine. Plos One. 6: e17748. PMID 21412438 DOI: 10.1371/Journal.Pone.0017748 |
0.514 |
|
2011 |
Conrady CD, Halford WP, Carr DJ. Loss of the type I interferon pathway increases vulnerability of mice to genital herpes simplex virus 2 infection. Journal of Virology. 85: 1625-33. PMID 21147921 DOI: 10.1128/Jvi.01715-10 |
0.454 |
|
2010 |
Halford WP, Püschel R, Rakowski B. Herpes simplex virus 2 ICP0 mutant viruses are avirulent and immunogenic: implications for a genital herpes vaccine. Plos One. 5: e12251. PMID 20808928 DOI: 10.1371/Journal.Pone.0012251 |
0.556 |
|
2010 |
Liu M, Schmidt EE, Halford WP. ICP0 dismantles microtubule networks in herpes simplex virus-infected cells. Plos One. 5: e10975. PMID 20544015 DOI: 10.1371/Journal.Pone.0010975 |
0.583 |
|
2010 |
Liu M, Rakowski B, Gershburg E, Weisend CM, Lucas O, Schmidt EE, Halford WP. ICP0 antagonizes ICP4-dependent silencing of the herpes simplex virus ICP0 gene. Plos One. 5: e8837. PMID 20098619 DOI: 10.1371/Journal.Pone.0008837 |
0.579 |
|
2009 |
Imai Y, Apakupakul K, Krause PR, Halford WP, Margolis TP. Investigation of the mechanism by which herpes simplex virus type 1 LAT sequences modulate preferential establishment of latent infection in mouse trigeminal ganglia. Journal of Virology. 83: 7873-82. PMID 19493993 DOI: 10.1128/Jvi.00043-09 |
0.465 |
|
2009 |
Carr DJ, Austin BA, Halford WP, Stuart PM. Delivery of Interferon-gamma by an adenovirus vector blocks herpes simplex virus Type 1 reactivation in vitro and in vivo independent of RNase L and double-stranded RNA-dependent protein kinase pathways. Journal of Neuroimmunology. 206: 39-43. PMID 19042034 DOI: 10.1016/J.Jneuroim.2008.10.008 |
0.488 |
|
2007 |
Halford WP. Towards an effective genital herpes vaccine: past lessons and future prospects. Future Virology. 2: 1-6. PMID 23843891 DOI: 10.2217/17460794.2.1.1 |
0.446 |
|
2007 |
Austin BA, Halford WP, Williams BR, Carr DJ. Oligoadenylate synthetase/protein kinase R pathways and alphabeta TCR+ T cells are required for adenovirus vector: IFN-gamma inhibition of herpes simplex virus-1 in cornea. Journal of Immunology (Baltimore, Md. : 1950). 178: 5166-72. PMID 17404299 DOI: 10.4049/Jimmunol.178.8.5166 |
0.437 |
|
2006 |
Halford WP, Weisend C, Grace J, Soboleski M, Carr DJ, Balliet JW, Imai Y, Margolis TP, Gebhardt BM. ICP0 antagonizes Stat 1-dependent repression of herpes simplex virus: implications for the regulation of viral latency. Virology Journal. 3: 44. PMID 16764725 DOI: 10.1186/1743-422X-3-44 |
0.511 |
|
2006 |
Austin BA, Halford W, Silverman RH, Williams BR, Carr DJ. OAS and PKR are not required for the antiviral effect of Ad:IFN-gamma against acute HSV-1 in primary trigeminal ganglia cultures. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 26: 220-5. PMID 16704298 DOI: 10.1089/jir.2006.26.220 |
0.371 |
|
2005 |
Gebhardt BM, Halford WP. Evidence that spontaneous reactivation of herpes virus does not occur in mice. Virology Journal. 2: 67. PMID 16109179 DOI: 10.1186/1743-422X-2-67 |
0.515 |
|
2005 |
Pierce AT, DeSalvo J, Foster TP, Kosinski A, Weller SK, Halford WP. Beta interferon and gamma interferon synergize to block viral DNA and virion synthesis in herpes simplex virus-infected cells. The Journal of General Virology. 86: 2421-32. PMID 16099899 DOI: 10.1099/Vir.0.80979-0 |
0.505 |
|
2005 |
Halford WP, Maender JL, Gebhardt BM. Re-evaluating the role of natural killer cells in innate resistance to herpes simplex virus type 1. Virology Journal. 2: 56. PMID 16022737 DOI: 10.1186/1743-422X-2-56 |
0.499 |
|
2005 |
Halford WP, Halford KJ, Pierce AT. Mathematical analysis demonstrates that interferons-beta and -gamma interact in a multiplicative manner to disrupt herpes simplex virus replication. Journal of Theoretical Biology. 234: 439-54. PMID 15784277 DOI: 10.1016/J.Jtbi.2004.12.007 |
0.422 |
|
2005 |
Al-Khatib K, Williams BR, Silverman RH, Halford W, Carr DJ. Dichotomy between survival and lytic gene expression in RNase L- and PKR-deficient mice transduced with an adenoviral vector expressing murine IFN-beta following ocular HSV-1 infection. Experimental Eye Research. 80: 167-73. PMID 15670795 DOI: 10.1016/J.Exer.2004.08.026 |
0.487 |
|
2004 |
Halford WP, Balliet JW, Gebhardt BM. Re-evaluating natural resistance to herpes simplex virus type 1. Journal of Virology. 78: 10086-95. PMID 15331741 DOI: 10.1128/Jvi.78.18.10086-10095.2004 |
0.44 |
|
2004 |
Al-Khatib K, Williams BR, Silverman RH, Halford W, Carr DJ. Distinctive roles for 2',5'-oligoadenylate synthetases and double-stranded RNA-dependent protein kinase R in the in vivo antiviral effect of an adenoviral vector expressing murine IFN-beta. Journal of Immunology (Baltimore, Md. : 1950). 172: 5638-47. PMID 15100308 DOI: 10.4049/jimmunol.172.9.5638 |
0.407 |
|
2003 |
Al-khatib K, Williams BR, Silverman RH, Halford W, Carr DJ. The murine double-stranded RNA-dependent protein kinase PKR and the murine 2',5'-oligoadenylate synthetase-dependent RNase L are required for IFN-beta-mediated resistance against herpes simplex virus type 1 in primary trigeminal ganglion culture. Virology. 313: 126-35. PMID 12951027 DOI: 10.1016/S0042-6822(03)00298-8 |
0.456 |
|
2002 |
Al-Khatib K, Williams BR, Silverman RH, Halford WP, Carr DJ. Absence of PKR attenuates the anti-HSV-1 activity of an adenoviral vector expressing murine IFN-beta. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 22: 861-71. PMID 12396725 DOI: 10.1089/107999002760274872 |
0.461 |
|
2002 |
Sainz B, Halford WP. Alpha/Beta interferon and gamma interferon synergize to inhibit the replication of herpes simplex virus type 1. Journal of Virology. 76: 11541-50. PMID 12388715 DOI: 10.1128/Jvi.76.22.11541-11550.2002 |
0.467 |
|
2002 |
Härle P, Sainz B, Carr DJ, Halford WP. The immediate-early protein, ICP0, is essential for the resistance of herpes simplex virus to interferon-alpha/beta. Virology. 293: 295-304. PMID 11886249 DOI: 10.1006/Viro.2001.1280 |
0.473 |
|
2001 |
Halford WP, Kemp CD, Isler JA, Davido DJ, Schaffer PA. ICP0, ICP4, or VP16 expressed from adenovirus vectors induces reactivation of latent herpes simplex virus type 1 in primary cultures of latently infected trigeminal ganglion cells. Journal of Virology. 75: 6143-53. PMID 11390616 DOI: 10.1128/Jvi.75.13.6143-6153.2001 |
0.411 |
|
2001 |
Halford WP, Schaffer PA. ICP0 is required for efficient reactivation of herpes simplex virus type 1 from neuronal latency Journal of Virology. 75: 3240-3249. PMID 11238850 DOI: 10.1128/Jvi.75.7.3240-3249.2001 |
0.401 |
|
2000 |
Halford WP, Schaffer PA. Optimized viral dose and transient immunosuppression enable herpes simplex virus ICP0-null mutants to establish wild-type levels of latency in vivo Journal of Virology. 74: 5957-5967. PMID 10846077 DOI: 10.1128/Jvi.74.13.5957-5967.2000 |
0.392 |
|
1998 |
Hill JM, Wen R, Halford WP. Pathogenesis and Molecular Biology of HSV Latency and Ocular Reactivation in the Rabbit. Methods in Molecular Medicine. 10: 291-315. PMID 21374237 DOI: 10.1385/0-89603-347-3:291 |
0.344 |
|
1998 |
Carr DJ, Halford WP, Veress LA, Noisakran S, Perng GC, Wechsler SL. The persistent elevated cytokine mRNA levels in trigeminal ganglia of mice latently infected with HSV-1 are not due to the presence of latency associated transcript (LAT) RNAs. Virus Research. 54: 1-8. PMID 9660066 DOI: 10.1016/S0168-1702(98)00007-0 |
0.441 |
|
1998 |
Halford WP, Veress LA, Gebhardt BM, Carr DJ. Immunization with HSV-1 antigen rapidly protects against HSV-1-induced encephalitis and is IFN-gamma independent. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 18: 151-8. PMID 9555976 |
0.369 |
|
1997 |
Halford WP, Gebhardt BM, Carr DJJ. Acyclovir blocks cytokine gene expression in trigeminal ganglia latently infected with herpes simplex virus type 1 Virology. 238: 53-63. PMID 9375008 DOI: 10.1006/viro.1997.8806 |
0.378 |
|
1997 |
Halford WP, Veress LA, Gebhardt BM, Carr DJ. Innate and acquired immunity to herpes simplex virus type 1. Virology. 236: 328-37. PMID 9325240 DOI: 10.1006/viro.1997.8738 |
0.407 |
|
1996 |
Halford WP, Gebhardt BM, Carr DJJ. Persistent Cytokine Expression in Trigeminal Ganglion Latently Infected with Herpes Simplex Virus Type 1 Journal of Immunology. 157: 3542-3549. PMID 8871654 |
0.329 |
|
1996 |
Hill JM, Gebhardt BM, Wen R, Bouterie AM, Thompson HW, O'Callaghan RJ, Halford WP, Kaufman HE. Quantitation of herpes simplex virus type 1 DNA and latency-associated transcripts in rabbit trigeminal ganglia demonstrates a stable reservoir of viral nucleic acids during latency. Journal of Virology. 70: 3137-41. PMID 8627793 DOI: 10.1128/Jvi.70.5.3137-3141.1996 |
0.439 |
|
1996 |
Halford WP, Gebhardt BM, Carr DJJ. Active immunization blocks efficient establishment of latent herpes simplex virus type 1 infection Faseb Journal. 10. |
0.414 |
|
1995 |
Halford WP, Carr DJJ. Subversion of intracellular signal transduction by Herpes simplex virus type 1 Advances in Neuroimmunology. 5: 327-334. PMID 8748076 DOI: 10.1016/0960-5428(95)00017-V |
0.326 |
|
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