Year |
Citation |
Score |
2023 |
Centa JL, Stratton MP, Pratt MA, Osterlund Oltmanns JR, Wallace DG, Miller SA, Weimer JM, Hastings ML. Protracted CLN3 Batten disease in mice that genetically model an exon-skipping therapeutic approach. Molecular Therapy. Nucleic Acids. 33: 15-27. PMID 37359347 DOI: 10.1016/j.omtn.2023.05.025 |
0.326 |
|
2023 |
Hastings ML, Krainer AR. RNA therapeutics. Rna (New York, N.Y.). 29: 393-395. PMID 36928165 DOI: 10.1261/rna.079626.123 |
0.494 |
|
2022 |
Michaels WE, Pena-Rasgado C, Kotaria R, Bridges RJ, Hastings ML. Open reading frame correction using splice-switching antisense oligonucleotides for the treatment of cystic fibrosis. Proceedings of the National Academy of Sciences of the United States of America. 119. PMID 35017302 DOI: 10.1073/pnas.2114886119 |
0.366 |
|
2020 |
Frederiksen SB, Holm LL, Larsen MR, Doktor TK, Andersen HS, Hastings ML, Hua Y, Krainer AR, Andresen BS. Identification of SRSF10 as a regulator of SMN2 ISS-N1. Human Mutation. PMID 33300159 DOI: 10.1002/humu.24149 |
0.563 |
|
2020 |
Moissoglu K, Stueland M, Gasparski AN, Wang T, Jenkins LM, Hastings ML, Mili S. RNA localization and co-translational interactions control RAB13 GTPase function and cell migration. The Embo Journal. e2020104958. PMID 32946136 DOI: 10.15252/embj.2020104958 |
0.343 |
|
2016 |
Havens MA, Hastings ML. Splice-switching antisense oligonucleotides as therapeutic drugs. Nucleic Acids Research. PMID 27288447 DOI: 10.1093/nar/gkw533 |
0.459 |
|
2014 |
Wee CD, Havens MA, Jodelka FM, Hastings ML. Targeting SR proteins improves SMN expression in spinal muscular atrophy cells. Plos One. 9: e115205. PMID 25506695 DOI: 10.1371/Journal.Pone.0115205 |
0.407 |
|
2013 |
Havens MA, Duelli DM, Hastings ML. Targeting RNA splicing for disease therapy. Wiley Interdisciplinary Reviews. Rna. 4: 247-66. PMID 23512601 DOI: 10.1002/Wrna.1158 |
0.391 |
|
2010 |
Jodelka FM, Ebert AD, Duelli DM, Hastings ML. A feedback loop regulates splicing of the spinal muscular atrophy-modifying gene, SMN2. Human Molecular Genetics. 19: 4906-17. PMID 20884664 DOI: 10.1093/Hmg/Ddq425 |
0.461 |
|
2010 |
Salato VK, Rediske NW, Zhang C, Hastings ML, Munroe SH. An exonic splicing enhancer within a bidirectional coding sequence regulates alternative splicing of an antisense mRNA. Rna Biology. 7: 179-90. PMID 20200494 DOI: 10.4161/rna.7.2.11182 |
0.353 |
|
2009 |
Hastings ML, Berniac J, Liu YH, Abato P, Jodelka FM, Barthel L, Kumar S, Dudley C, Nelson M, Larson K, Edmonds J, Bowser T, Draper M, Higgins P, Krainer AR. Tetracyclines that promote SMN2 exon 7 splicing as therapeutics for spinal muscular atrophy. Science Translational Medicine. 1: 5ra12. PMID 20161659 DOI: 10.1126/Scitranslmed.3000208 |
0.53 |
|
2009 |
Martins de Araújo M, Bonnal S, Hastings ML, Krainer AR, Valcárcel J. Differential 3' splice site recognition of SMN1 and SMN2 transcripts by U2AF and U2 snRNP. Rna (New York, N.Y.). 15: 515-23. PMID 19244360 DOI: 10.1261/rna.1273209 |
0.642 |
|
2007 |
Zhang C, Hastings ML, Krainer AR, Zhang MQ. Dual-specificity splice sites function alternatively as 5' and 3' splice sites. Proceedings of the National Academy of Sciences of the United States of America. 104: 15028-33. PMID 17848517 DOI: 10.1073/Pnas.0703773104 |
0.632 |
|
2007 |
Hastings ML, Allemand E, Duelli DM, Myers MP, Krainer AR. Control of pre-mRNA splicing by the general splicing factors PUF60 and U2AF(65). Plos One. 2: e538. PMID 17579712 DOI: 10.1371/Journal.Pone.0000538 |
0.662 |
|
2007 |
Allemand E, Hastings ML, Murray MV, Myers MP, Krainer AR. Alternative splicing regulation by interaction of phosphatase PP2Cgamma with nucleic acid-binding protein YB-1. Nature Structural & Molecular Biology. 14: 630-8. PMID 17572683 DOI: 10.1038/Nsmb1257 |
0.585 |
|
2006 |
Sheth N, Roca X, Hastings ML, Roeder T, Krainer AR, Sachidanandam R. Comprehensive splice-site analysis using comparative genomics. Nucleic Acids Research. 34: 3955-67. PMID 16914448 DOI: 10.1093/Nar/Gkl556 |
0.602 |
|
2006 |
Cartegni L, Hastings ML, Calarco JA, de Stanchina E, Krainer AR. Determinants of exon 7 splicing in the spinal muscular atrophy genes, SMN1 and SMN2. American Journal of Human Genetics. 78: 63-77. PMID 16385450 DOI: 10.1086/498853 |
0.63 |
|
2005 |
Hastings ML, Resta N, Traum D, Stella A, Guanti G, Krainer AR. An LKB1 AT-AC intron mutation causes Peutz-Jeghers syndrome via splicing at noncanonical cryptic splice sites. Nature Structural & Molecular Biology. 12: 54-9. PMID 15608654 DOI: 10.1038/Nsmb873 |
0.632 |
|
2001 |
Hastings ML, Wilson CM, Munroe SH. A purine-rich intronic element enhances alternative splicing of thyroid hormone receptor mRNA Rna. 7: 859-874. PMID 11421362 DOI: 10.1017/S1355838201002084 |
0.516 |
|
2001 |
Hastings ML, Krainer AR. Pre-mRNA splicing in the new millennium. Current Opinion in Cell Biology. 13: 302-9. PMID 11343900 DOI: 10.1016/S0955-0674(00)00212-X |
0.592 |
|
2001 |
Hastings ML, Krainer AR. Functions of SR proteins in the U12-dependent AT-AC pre-mRNA splicing pathway. Rna (New York, N.Y.). 7: 471-82. PMID 11333026 DOI: 10.1017/S1355838201002552 |
0.607 |
|
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